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Indiana

$243+ Cheap flights from Panama to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
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Cheap flight deals from Panama to Indiana

Cheapest flights from Panama to Indiana
Explore the most affordable flight options available from Panama to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This Trip.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:10 am
PTY
-
ORD
2 stops13h 49m
Multiple Airlines
Thu 4/2311:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/18$353
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:55 am
PTY
-
ORD
2 stops16h 23m
Multiple Airlines
Sun 3/811:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Deal found 2/19$357
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:55 pm
PTY
-
ORD
2 stops15h 55m
Multiple Airlines
Sun 4/1911:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/19$372
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:50 pm
PTY
-
ORD
2 stops20h 58m
Multiple Airlines
Thu 4/211:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/18$375
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:10 pm
PTY
-
ORD
2 stops32h 49m
Multiple Airlines
Sun 5/1011:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/18$376
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:55 pm
PTY
-
ORD
2 stops19h 44m
Multiple Airlines
Sat 3/710:20 pm
ORD
-
PTY
1 stop17h 35m
Multiple Airlines
Deal found 2/18$378
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:05 am
PTY
-
ORD
2 stops15h 26m
Multiple Airlines
Thu 4/1611:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/19$379
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:05 am
PTY
-
ORD
2 stops18h 12m
Multiple Airlines
Tue 5/1211:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/18$393
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/212:55 am
PTY
-
ORD
2 stops29h 30m
Multiple Airlines
Sun 3/2911:20 pm
ORD
-
PTY
1 stop17h 40m
Multiple Airlines
Deal found 2/20$395
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:20 pm
PTY
-
CVG
2 stops21h 47m
American Airlines
Tue 9/156:49 am
CVG
-
PTY
2 stops8h 21m
American Airlines
Deal found 2/18$436
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:49 pm
PTY
-
IND
1 stop9h 10m
American Airlines
Thu 5/217:27 pm
IND
-
PTY
1 stop17h 47m
American Airlines
Deal found 2/19$476
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:45 am
PTY
-
SDF
1 stop11h 37m
United Airlines
Mon 5/113:30 pm
SDF
-
PTY
1 stop23h 44m
United Airlines
Deal found 2/17$482

Find flight deals from Panama to Indiana

Keep the following information in mind while searching for Panama to Indiana flight deals. Data was last updated February 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$353
(Trip.com)

One-way from

$243
(Kiwi.com)

Popular in

August

Cheapest in

March

Average price

$644
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
Search Deals
From Panama to Indiana
Search Deals
One-way flight from Panama to Indiana
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Panama to Indiana that are best for you.

Fly from

Panama

Fly to

Indiana

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 4/13

6:34 pm-9:50 am

1 stop15h 16m

Chicago O'Hare Intl

Sun 4/19

11:20 pm-9:15 am

1 stop9h 55m

$411

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 5/2

9:33 pm-11:59 pm

1 stop26h 26m

Chicago O'Hare Intl

Thu 5/7

11:20 pm-9:15 am

1 stop9h 55m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 4/9

3:00 pm-2:00 pm

1 stop23h 00m

Chicago O'Hare Intl

Thu 4/16

11:20 pm-5:00 pm

1 stop17h 40m

$448

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 3/30

5:55 pm-9:20 pm

1 stop27h 25m

Chicago O'Hare Intl

Thu 4/2

11:20 pm-9:15 am

1 stop9h 55m

$475

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 4/16

1:49 pm-11:59 pm

1 stop9h 10m

Indianapolis

Thu 5/21

7:27 pm-12:14 pm

1 stop17h 47m

$476

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 5/1

10:55 pm-2:54 pm

2 stops14h 59m

Louisville Intl

Mon 5/11

7:36 pm-2:14 pm

2 stops19h 38m

$482

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 5/26

7:55 am-10:15 pm

1 stop13h 20m

Louisville Intl

Thu 5/28

9:30 am-4:12 pm

1 stop7h 42m

$491

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/16

7:55 am-11:56 pm

2 stops15h 01m

Louisville Intl

Sun 5/24

7:37 pm-2:14 pm

2 stops19h 37m

$496

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 5/28

1:14 pm-6:32 pm

1 stop28h 18m

Indianapolis

Thu 6/4

7:27 pm-12:14 pm

1 stop17h 47m

$521

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 3/3

2:40 pm-10:44 pm

1 stop8h 04m

Indianapolis

Wed 3/18

8:04 pm-2:20 pm

2 stops19h 16m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 60 results
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Best time to book a flight from Panama to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indiana

What is the cheapest month to book a flight from Panama to Indiana?

Currently, February is the cheapest month in which you can book a flight from Panama to Indiana (average of $301). Flying from Panama to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 20, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Panama to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,215 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,215 reviews
Delta
7.9
Good
8,215 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,325 reviews
Delta
7.9
Good
8,215 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Indiana?

    There are many flights that can get you from Panama to Indiana in 9h 10m. Fly via Avianca, American Airlines, or United Airlines to get the fastest option. The distance from Panama to Indiana is about 2158 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Indiana that include hotel bookings?

    Yes. In addition to deals on Panama to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indiana.

  • Can I find deals for business class flights from Panama to Indiana?

    Yes. Cheapflights offers flight deals from Panama to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indiana?

    Currently, February is the cheapest month in which you can book a flight from Panama to Indiana (average of $301). Flying from Panama to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Indiana

Discover the top 2 airlines that operate flights from Panama to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$311Average$568FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$458Average$665FlexibilityNo cancel feeOn-time69%

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