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$272+ Cheap flights from Panama to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from Panama to Indiana

Cheapest flights from Panama to Indiana
Explore the most affordable flight options available from Panama to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:55 amPTY - IND
1 stop25h 55mUnited Airlines
Fri 2/206:10 pmIND - PTY
2 stops22h 57mUnited Airlines
Deal found 12/29$592
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:00 amPTY - SDF
2 stops12h 30mUnited Airlines
Sun 1/113:30 pmSDF - PTY
1 stop25h 37mUnited Airlines
Deal found 12/29$636
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:00 amPTY - IND
1 stop9h 56mUnited Airlines
Sun 1/45:05 pmIND - PTY
1 stop24h 02mUnited Airlines
Deal found 12/29$636
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:53 pmPTY - IND
1 stop9h 06mAmerican Airlines
Fri 1/96:00 amIND - PTY
1 stop9h 38mAmerican Airlines
Deal found 12/28$645
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:00 amPTY - SDF
2 stops12h 30mUnited Airlines
Fri 1/99:15 amSDF - PTY
1 stop7h 52mUnited Airlines
Deal found 12/29$657
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:55 pmPTY - IND
1 stop17h 48mAmerican Airlines
Fri 1/96:00 amIND - PTY
1 stop9h 38mAmerican Airlines
Deal found 12/28$666
This Avianca deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:55 amPTY - ORD
1 stop18h 25mAvianca
Thu 1/294:10 pmORD - PTY
1 stop17h 20mAvianca
Deal found 12/28$697
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:45 amPTY - ORD
1 stop11h 35mMultiple Airlines
Sun 1/117:20 amORD - PTY
2 stops26h 10mMultiple Airlines
Deal found 12/27$702
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:53 pmPTY - SDF
1 stop9h 06mAmerican Airlines
Fri 1/96:00 amSDF - PTY
1 stop9h 38mAmerican Airlines
Deal found 12/29$703
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:28 pmPTY - ORD
1 stop17h 22mMultiple Airlines
Mon 1/57:30 amORD - PTY
2 stops26h 00mMultiple Airlines
Deal found 12/28$719
This Trip.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:55 amPTY - ORD
1 stop18h 25mAvianca
Sat 1/34:10 pmORD - PTY
1 stop17h 20mAvianca
Deal found 12/28$736
This Gotogate deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:50 pmPTY - IND
2 stops14h 39mAvianca
Sun 1/45:45 amIND - PTY
3 stops37h 10mAvianca
Deal found 12/29$753

Find flight deals from Panama to Indiana

Keep the following information in mind while searching for Panama to Indiana flight deals. Data was last updated December 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$449
(United Airlines)

One-way from

$272
(Kiwi.com)

Popular in

August

Cheapest in

December

Average price

$516
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
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From Panama to Indiana
Search Deals
One-way flight from Panama to Indiana
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Panama to Indiana that are best for you.

Fly from

Panama

Fly to

Indiana

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 5/1

10:55 pm-1:00 pm

2 stops13h 05m

Louisville Intl

Mon 5/11

7:20 pm-2:14 pm

2 stops19h 54m

$449

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 1/31

4:41 pm-1:14 pm

1 stop20h 33m

Louisville Intl

Mon 3/9

3:30 pm-6:38 pm

1 stop28h 08m

$451

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 3/3

4:41 pm-10:48 am

1 stop18h 07m

Indianapolis

Wed 3/18

9:00 am-4:07 pm

1 stop8h 07m

$505

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 1/25

2:55 am-6:16 pm

2 stops16h 21m

Chicago O'Hare Intl

Mon 2/2

9:23 am-10:30 am

3 stops24h 07m

$528

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 3/3

2:40 pm-10:25 am

2 stops19h 45m

Indianapolis

Wed 3/18

5:30 pm-12:40 pm

2 stops20h 10m

$528

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 2/12

2:55 am-7:23 pm

2 stops16h 28m

Indianapolis

Fri 2/20

5:45 am-12:40 am

2 stops18h 55m

$539

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 2/12

10:26 am-10:34 pm

1 stop13h 08m

Chicago Midway

Thu 2/19

6:15 am-1:00 am

2 stops17h 45m

$563

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/30

2:55 am-6:16 pm

2 stops16h 21m

Chicago O'Hare Intl

Thu 2/5

9:23 am-1:00 am

2 stops14h 37m

$563

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Fri 2/13

10:00 am-11:26 am

2 stops25h 26m

Indianapolis

Fri 2/20

5:08 pm-5:07 pm

1 stop23h 59m

$569

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 1/27

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Sat 1/31

10:20 pm-8:50 am

1 stop9h 30m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 53 results
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Best time to book a flight from Panama to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indiana

What is the cheapest month to book a flight from Panama to Indiana?

Currently, February is the cheapest month in which you can book a flight from Panama to Indiana (average of $298). Flying from Panama to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated December 30, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Panama to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,017 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,017 reviews
Delta
7.9
Good
8,017 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,122 reviews
Delta
7.9
Good
8,017 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Indiana?

    There are many flights that can get you from Panama to Indiana in 8h 02m. Fly via United Airlines, Avianca, or Delta to get the fastest option. The distance from Panama to Indiana is about 2316 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Indiana that include hotel bookings?

    Yes. In addition to deals on Panama to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indiana.

  • Can I find deals for business class flights from Panama to Indiana?

    Yes. Cheapflights offers flight deals from Panama to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indiana?

    Currently, February is the cheapest month in which you can book a flight from Panama to Indiana (average of $298). Flying from Panama to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Indiana

Discover the top 2 airlines that operate flights from Panama to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$344Average$590FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$659FlexibilityNo cancel feeOn-time69%

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