$54+ Cheap flights from Knoxville (TYS) to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Jul 20 — Jul 271
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IndianaExplore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/121:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Sun 7/192:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$159
This Super.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Thu 7/232:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:23 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Sun 8/92:49 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$194
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Sun 7/192:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- MDW
2 stops16h 22m
Multiple Airlines
Thu 8/132:49 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:56 pm
TYS
- MDW
2 stops24h 03m
Allegiant Air
Sun 8/162:49 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$215
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
TYS
- MDW
1 stop5h 37m
Delta
Sun 9/136:00 am
MDW
- TYS
1 stop6h 24m
Delta
Deal found 6/18![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:12 pm
TYS
- ORD
1 stop6h 45m
Delta
Fri 8/289:54 am
ORD
- TYS
1 stop6h 25m
Delta
Deal found 6/19![Delta logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:40 pm
TYS
- MDW
2 stops34h 23m
Multiple Airlines
Thu 7/162:48 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:09 pm
TYS
- MDW
1 stop20h 39m
Allegiant Air
Mon 11/94:31 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$224
This Mytrip deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/282:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:38 pm
TYS
- CVG
1 stop4h 50m
Allegiant Air
Sun 9/276:15 am
CVG
- TYS
1 stop16h 21m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$230
Best flights from Knoxville to IndianaDiscover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 20, 2026.
Discover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
TYS
- CVG
1 stop16h 45m
Multiple Airlines
Fri 7/1012:53 pm
CVG
- TYS
2 stops9h 07m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$240
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:45 pm
TYS
- MDW
1 stop5h 55m
Southwest
Sat 8/296:45 am
MDW
- TYS
1 stop5h 30m
Southwest
Deal found 6/15![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sun 7/265:59 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 6/15![United Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:23 pm
TYS
- CVG
1 stop7h 23m
Allegiant Air
Wed 7/228:00 am
CVG
- TYS
1 stop9h 59m
Allegiant Air
Deal found 6/17![Allegiant Air logo]()
$254
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/133:59 pm
TYS
- SBN
1 stop4h 50m
Delta
Wed 7/293:09 pm
SBN
- TYS
1 stop6h 29m
Delta
Deal found 6/16![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:13 pm
TYS
- ORD
Nonstop2h 02m
American Airlines
Sun 7/55:00 am
ORD
- TYS
1 stop5h 27m
American Airlines
Deal found 6/19![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
TYS
- ORD
Nonstop1h 57m
United Airlines
Sun 8/236:06 pm
ORD
- TYS
Nonstop1h 47m
United Airlines
Deal found 6/16![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:55 pm
TYS
- MDW
1 stop3h 15m
Southwest
Fri 7/105:20 pm
MDW
- TYS
1 stop4h 15m
Southwest
Deal found 6/15![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:40 am
TYS
- MDW
1 stop4h 45m
Delta
Sun 9/136:00 am
MDW
- TYS
1 stop4h 05m
Delta
Deal found 6/15![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:17 pm
TYS
- CVG
2 stops18h 26m
Multiple Airlines
Sun 9/276:15 am
CVG
- TYS
1 stop16h 21m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$280
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:45 pm
TYS
- MDW
1 stop3h 25m
Southwest
Mon 8/105:30 am
MDW
- TYS
1 stop6h 55m
Southwest
Deal found 6/19![Southwest logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:34 pm
TYS
- CVG
1 stop7h 21m
Allegiant Air
Sun 10/1112:52 pm
CVG
- TYS
1 stop9h 31m
Allegiant Air
Deal found 6/17![Allegiant Air logo]()
$295
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:15 am
TYS
- MDW
1 stop6h 24m
Delta
Tue 8/1112:46 pm
MDW
- TYS
1 stop6h 24m
Delta
Deal found 6/19![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
TYS
- SBN
1 stop5h 06m
United Airlines
Tue 7/149:54 am
SBN
- TYS
1 stop4h 33m
United Airlines
Deal found 6/17![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:05 pm
TYS
- IND
1 stop11h 53m
Multiple Airlines
Sun 7/1911:00 am
IND
- TYS
1 stop12h 03m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:10 am
TYS
- MDW
2 stops6h 05m
Southwest
Thu 8/208:10 am
MDW
- TYS
2 stops8h 00m
Southwest
Deal found 6/16![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:40 am
TYS
- MDW
1 stop5h 19m
Delta
Tue 8/116:05 am
MDW
- TYS
1 stop4h 06m
Delta
Deal found 6/19![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:53 pm
TYS
- CVG
1 stop7h 36m
Allegiant Air
Fri 7/173:08 pm
CVG
- TYS
1 stop18h 54m
Allegiant Air
Deal found 6/17![Allegiant Air logo]()
$315
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sun 7/56:55 am
ORD
- TYS
Nonstop1h 48m
United Airlines
Deal found 6/19![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:40 am
TYS
- ORD
1 stop6h 24m
Delta
Mon 9/215:30 am
ORD
- TYS
1 stop4h 35m
Delta
Deal found 6/17![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:01 am
TYS
- ORD
1 stop6h 42m
American Airlines
Sun 6/288:05 am
ORD
- TYS
Nonstop1h 53m
American Airlines
Deal found 6/19![American Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:25 am
TYS
- MDW
2 stops7h 30m
Southwest
Sun 9/205:10 am
MDW
- TYS
1 stop8h 50m
Southwest
Deal found 6/16![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:38 pm
TYS
- ORD
1 stop5h 17m
Delta
Sat 8/88:05 am
ORD
- TYS
1 stop6h 25m
Delta
Deal found 6/19![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:10 am
TYS
- MDW
2 stops6h 55m
Southwest
Wed 7/227:45 am
MDW
- TYS
2 stops8h 15m
Southwest
Deal found 6/17![Southwest logo]()
$278
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:15 pm
TYS
- AZO
1 stop4h 22m
American Airlines
Sat 9/196:00 am
AZO
- TYS
2 stops11h 46m
American Airlines
Deal found 6/18![American Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Mon 8/35:55 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 6/18![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:15 am
TYS
- ORD
1 stop6h 53m
Delta
Sun 8/165:30 am
ORD
- TYS
1 stop4h 41m
Delta
Deal found 6/18![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:10 am
TYS
- MDW
1 stop6h 50m
Southwest
Sat 8/86:35 am
MDW
- TYS
2 stops11h 45m
Southwest
Deal found 6/19![Southwest logo]()
$283
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1311:03 am
TYS
- AZO
2 stops12h 37m
American Airlines
Mon 7/203:39 pm
AZO
- TYS
2 stops8h 12m
American Airlines
Deal found 6/15![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am
TYS
- IND
1 stop4h 20m
United Airlines
Wed 11/46:00 am
IND
- TYS
1 stop3h 59m
United Airlines
Deal found 6/17![United Airlines logo]()
$335
Last-minute flights from Knoxville to IndianaDiscover last-minute flight deals from Knoxville to Indiana. Data last updated June 20, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Indiana. Data last updated June 20, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/282:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
TYS
- CVG
1 stop16h 45m
Multiple Airlines
Fri 7/1012:53 pm
CVG
- TYS
2 stops9h 07m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$240
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:35 am
TYS
- ORD
Nonstop2h 03m
American Airlines
Mon 7/139:40 am
ORD
- TYS
Nonstop1h 50m
American Airlines
Deal found 6/17![American Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
- MDW
2 stops31h 19m
Multiple Airlines
Thu 7/162:48 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:40 pm
TYS
- MDW
2 stops34h 23m
Multiple Airlines
Thu 7/162:48 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:40 pm
TYS
- MDW
2 stops23h 27m
Multiple Airlines
Sun 7/122:48 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$233
This Cheapflightsfares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/121:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Sun 7/192:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$159
This Super.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Thu 7/232:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$173
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Sun 7/192:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:11 pm
TYS
- MDW
2 stops25h 52m
Multiple Airlines
Thu 7/232:48 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:53 pm
TYS
- ORD
2 stops24h 22m
Multiple Airlines
Wed 7/228:05 am
ORD
- TYS
1 stop8h 54m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:22 pm
TYS
- MDW
Nonstop1h 36m
Multiple Airlines
Mon 8/36:05 am
MDW
- TYS
2 stops14h 55m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$238
One-way flights from Knoxville to IndianaSearch for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated June 20, 2026.
Search for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated June 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$54
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/91:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$63
This Trip.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/121:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 6/16![Allegiant Air logo]()
$64
This Cheapflightsfares deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$82
This Cheapflightsfares deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:05 pm
TYS
- IND
1 stop25h 00m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:21 pm
TYS
- CVG
1 stop19h 53m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:00 pm
TYS
- ORD
1 stop20h 15m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:26 am
TYS
- ORD
1 stop27h 49m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:53 pm
TYS
- CVG
1 stop7h 36m
Allegiant Air
Deal found 6/16![Allegiant Air logo]()
$116
Find flight deals from Knoxville to Indiana
Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated June 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $159 (Cheapflightsfares) |
One-way from | $54 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $655 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Knoxville to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleCincinnati
TYS - CVG
TYSCVG
Knoxville McGhee Tyson
Sat 7/4
6:00 am-10:45 pm
1 stop16h 45m
Cincinnati Cinci./N. Kentucky
Fri 7/10
12:53 pm-10:00 pm
2 stops9h 07m
$240
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Wed 8/26
12:45 pm-5:40 pm
1 stop5h 55m
Chicago Midway
Sat 8/29
6:45 am-1:15 pm
1 stop5h 30m
$247
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Fri 7/24
6:00 am-6:59 am
Nonstop1h 59m
Chicago O'Hare Intl
Sun 7/26
5:59 pm-8:48 pm
Nonstop1h 49m
$249
Quickest round-trip
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Thu 8/20
7:00 am-7:57 am
Nonstop1h 57m
Chicago O'Hare Intl
Sun 8/23
6:06 pm-8:53 pm
Nonstop1h 47m
$249
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Tue 7/7
6:55 pm-9:10 pm
1 stop3h 15m
Chicago Midway
Fri 7/10
5:20 pm-10:35 pm
1 stop4h 15m
$253
KnoxvilleCincinnati
TYS - CVG
TYSCVG
Knoxville McGhee Tyson
Wed 7/15
2:23 pm-9:46 pm
1 stop7h 23m
Cincinnati Cinci./N. Kentucky
Wed 7/22
8:00 am-5:59 pm
1 stop9h 59m
$254
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Thu 8/6
5:45 pm-8:10 pm
1 stop3h 25m
Chicago Midway
Mon 8/10
5:30 am-1:25 pm
1 stop6h 55m
$257
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Mon 8/17
7:10 am-12:15 pm
2 stops6h 05m
Chicago Midway
Thu 8/20
8:10 am-5:10 pm
2 stops8h 00m
$267
KnoxvilleSouth Bend
TYS - SBN
TYSSBN
Knoxville McGhee Tyson
Mon 7/13
3:59 pm-8:49 pm
1 stop4h 50m
South Bend/Michiana
Wed 7/29
3:09 pm-9:38 pm
1 stop6h 29m
$269
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Thu 9/10
11:40 am-3:25 pm
1 stop4h 45m
Chicago Midway
Sun 9/13
6:00 am-11:05 am
1 stop4h 05m
$269
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
TYS-MDW
TYS-ORD
TYS-CVG
TYS-SBN
TYS-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Indiana
TYS-USIN
TYS-MDW
TYS-ORD
TYS-CVG
TYS-SBN
What is the cheapest month to book a flight from Knoxville to Indiana?
Currently, June is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $41). Flying from Knoxville to Indiana in January is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to IN?
Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 20, 2026.
It’s optimal to fly from Knoxville to Indiana at noon. By choosing this option you can save up to 86% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Knoxville to Indiana?
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated June 20, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Indiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Indiana
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Complete your trip
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Knoxville and Indiana flights
Browse other Knoxville and Indiana flight options. Last updated on June 20, 2026.
Popular flight searches
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Knoxville to Indiana flights
Consider these flights traveling from Knoxville to Indiana.
Top 4 airlines flying from Knoxville to Indiana
Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$31 | Average$76 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$213 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$278 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$273 | FlexibilityNo cancel fee | On-time71% |