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$56+ Cheap flights from Knoxville (TYS) to Indiana

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Knoxville to Indiana

Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$56
(Booking.com)

Popular in

March

Cheapest in

July

Average price

$273

Good round-trip deal

$78 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Indianapolis flights.
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From Knoxville McGhee Tyson to Indiana
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Highest demand for flights based on searches. 10% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Indiana.
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Find flight deals from Knoxville to Indiana

Cheapest flights from Knoxville to Indiana
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/227:00 amTYS - SBN
1 stop25h 57mAllegiant Air
Fri 6/277:49 pmSBN - TYS
Nonstop1h 20mAllegiant Air
Deal found 4/30$190
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/127:00 amTYS - ORD
Nonstop1h 57mUnited Airlines
Mon 5/197:58 pmORD - TYS
Nonstop1h 47mUnited Airlines
Deal found 4/28$194
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:37 pmTYS - MDW
Nonstop1h 33mAllegiant Air
Sun 6/111:03 amMDW - TYS
1 stop26h 52mAllegiant Air
Deal found 4/29$195
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:05 amTYS - ORD
Nonstop2h 03mAmerican Airlines
Sun 5/1811:54 amORD - TYS
Nonstop1h 40mAmerican Airlines
Deal found 4/29$199
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/215:45 amTYS - IND
1 stop3h 11mDelta
Wed 5/286:00 amIND - TYS
1 stop3h 40mDelta
Deal found 4/29$209
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/145:30 amTYS - MDW
1 stop5h 21mDelta
Sun 8/176:00 amMDW - TYS
1 stop4h 07mDelta
Deal found 4/29$209
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/117:46 amTYS - ORD
1 stop6h 09mDelta
Sun 6/155:35 amORD - TYS
1 stop4h 33mDelta
Deal found 4/29$209
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/147:00 amTYS - CVG
1 stop6h 02mUnited Airlines
Sat 6/215:56 pmCVG - TYS
1 stop5h 09mUnited Airlines
Deal found 4/30$219
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/57:46 amTYS - AZO
1 stop3h 20mDelta
Fri 7/1811:46 amAZO - TYS
1 stop5h 46mDelta
Deal found 4/29$224
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/26:20 amTYS - ORD
1 stop13h 49mMultiple Airlines
Fri 6/69:08 pmORD - TYS
1 stop14h 42mMultiple Airlines
Deal found 4/29$225
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:51 amTYS - SBN
1 stop4h 42mAmerican Airlines
Wed 6/412:39 pmSBN - TYS
1 stop7h 17mAmerican Airlines
Deal found 4/29$234
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/254:15 pmTYS - IND
1 stop8h 44mMultiple Airlines
Thu 7/39:28 pmIND - TYS
1 stop16h 50mMultiple Airlines
Deal found 4/30$244

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Knoxville to Indiana that are best for you.

Fly from

Knoxville

Fly to

Indiana

Route

Depart

Return

Price

KnoxvilleSouth Bend

TYS - SBN

TYSSBN

Knoxville McGhee Tyson

Fri 5/30

1:31 pm-2:54 pm

Nonstop1h 23m

South Bend/Michiana

Mon 6/2

3:44 pm-5:04 pm

Nonstop1h 20m

$56

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Mon 6/2

5:38 pm-6:42 pm

Nonstop2h 04m

Chicago O'Hare Intl

Mon 6/16

7:55 pm-10:40 pm

Nonstop1h 45m

$194

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 5/30

5:37 pm-6:10 pm

Nonstop1h 33m

Chicago Midway

Sun 6/1

11:03 am-2:55 pm

1 stop26h 52m

$195

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 5/14

5:05 am-6:08 am

Nonstop2h 03m

Chicago O'Hare Intl

Sat 5/17

4:44 pm-7:25 pm

Nonstop1h 41m

$199

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Wed 5/21

5:45 am-8:56 am

1 stop3h 11m

Indianapolis

Wed 5/28

6:00 am-9:40 am

1 stop3h 40m

$209

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 8/14

5:30 am-9:51 am

1 stop5h 21m

Chicago Midway

Sun 8/17

6:00 am-11:07 am

1 stop4h 07m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 6/11

5:45 am-8:39 am

1 stop3h 54m

Chicago O'Hare Intl

Sun 6/15

5:35 am-11:08 am

1 stop4h 33m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 5/28

6:50 am-11:04 pm

2 stops17h 14m

Chicago O'Hare Intl

Thu 6/12

9:28 pm-11:50 am

1 stop13h 22m

$218

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Sat 6/14

7:00 am-1:02 pm

1 stop6h 02m

Cincinnati Cinci./N. Kentucky

Sat 6/21

5:56 pm-11:05 pm

1 stop5h 09m

$219

KnoxvilleKalamazoo

TYS - AZO

TYSAZO

Knoxville McGhee Tyson

Sat 7/5

7:46 am-11:06 am

1 stop3h 20m

Kalamazoo Intl

Wed 7/16

11:46 am-5:32 pm

1 stop5h 46m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 38 results
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Best time to book a flight from Knoxville to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Indiana

What is the cheapest month to book a flight from Knoxville to Indiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $297). Flying from Knoxville to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IN?

Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Knoxville to Indiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 1, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Knoxville to Indiana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,287 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Indiana?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Indiana. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Indiana one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $58. Frontier flights start at $108 while deals on American Airlines start at $120 one-way.

  • What are the most popular routes from Knoxville to Indiana?

    When deciding which route to take from Knoxville to Indiana consider Knoxville McGhee Tyson - Chicago O'Hare Intl, Knoxville McGhee Tyson - Chicago Midway or Knoxville McGhee Tyson - Indianapolis as they are the most popular.

  • Can I find deals for flights from Knoxville to Indiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Indiana.

  • Can I find deals for business class flights from Knoxville to Indiana?

    Yes. Cheapflights offers flight deals from Knoxville to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $297). Flying from Knoxville to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Indiana

Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$67Average$78FlexibilityNo cancel feeOn-time88%
DeltaCheapest$217Average$258FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$296FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$278FlexibilityNo cancel feeOn-time69%

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