$48+ Cheap flights from Knoxville (TYS) to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Jun 20 — Jun 271
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IndianaExplore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/142:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Fri 6/59:23 pm
MDW
- TYS
1 stop23h 15m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$180
This Cheapflightsfares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Sun 7/262:48 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:00 am
TYS
- MDW
2 stops15h 08m
Multiple Airlines
Thu 8/62:49 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:00 am
TYS
- MDW
1 stop24h 18m
Allegiant Air
Thu 8/62:49 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 5/20![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Fri 6/59:23 pm
MDW
- TYS
1 stop23h 15m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:09 pm
TYS
- MDW
1 stop20h 39m
Allegiant Air
Mon 11/94:31 pm
MDW
- TYS
Nonstop1h 30m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Fri 6/59:23 pm
MDW
- TYS
1 stop23h 15m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Thu 6/182:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/20![Allegiant Air logo]()
$205
This Cheapflightsfares deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/141:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/212:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:40 pm
TYS
- CVG
2 stops22h 34m
Multiple Airlines
Mon 6/226:30 am
CVG
- TYS
1 stop16h 13m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:22 pm
TYS
- CVG
1 stop18h 03m
Multiple Airlines
Sun 6/216:10 pm
CVG
- TYS
1 stop28h 33m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$214
Best flights from Knoxville to IndianaDiscover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
Discover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:22 pm
TYS
- CVG
1 stop18h 03m
Multiple Airlines
Sun 6/216:10 pm
CVG
- TYS
1 stop28h 33m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$214
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sat 6/206:07 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 5/18![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:30 am
TYS
- MDW
1 stop6h 03m
Delta
Mon 10/266:00 am
MDW
- TYS
1 stop4h 06m
Delta
Deal found 5/20![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:45 pm
TYS
- MDW
2 stops8h 50m
Southwest
Thu 8/65:15 am
MDW
- TYS
1 stop7h 10m
Southwest
Deal found 5/17![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:07 pm
TYS
- SBN
1 stop5h 27m
American Airlines
Mon 6/227:18 pm
SBN
- TYS
1 stop4h 29m
American Airlines
Deal found 5/17![American Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sat 6/136:07 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 5/19![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:45 am
TYS
- MDW
1 stop5h 14m
Delta
Sat 8/81:27 pm
MDW
- TYS
1 stop4h 59m
Delta
Deal found 5/19![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:45 pm
TYS
- MDW
1 stop3h 10m
Southwest
Wed 7/88:20 am
MDW
- TYS
2 stops7h 40m
Southwest
Deal found 5/20![Southwest logo]()
$272
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sat 6/206:07 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 5/16![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:40 am
TYS
- MDW
1 stop5h 25m
Delta
Thu 8/66:05 am
MDW
- TYS
1 stop4h 06m
Delta
Deal found 5/17![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:49 pm
TYS
- IND
2 stops46h 30m
Multiple Airlines
Sun 6/219:19 pm
IND
- TYS
1 stop14h 53m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:45 pm
TYS
- MDW
1 stop5h 20m
Southwest
Thu 8/67:25 am
MDW
- TYS
1 stop5h 00m
Southwest
Deal found 5/20![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sun 6/287:45 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 5/17![United Airlines logo]()
$262
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:15 am
TYS
- MDW
1 stop6h 31m
Delta
Tue 6/306:00 am
MDW
- TYS
1 stop4h 09m
Delta
Deal found 5/19![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:45 pm
TYS
- MDW
1 stop3h 10m
Southwest
Mon 6/225:05 pm
MDW
- TYS
1 stop3h 05m
Southwest
Deal found 5/18![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
TYS
- SBN
1 stop5h 06m
United Airlines
Tue 7/219:54 am
SBN
- TYS
1 stop4h 33m
United Airlines
Deal found 5/16![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:15 am
TYS
- ORD
1 stop4h 13m
Delta
Fri 8/75:28 am
ORD
- TYS
1 stop4h 43m
Delta
Deal found 5/20![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:07 pm
TYS
- IND
1 stop5h 59m
American Airlines
Sun 6/146:11 am
IND
- TYS
1 stop4h 25m
American Airlines
Deal found 5/20![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:45 pm
TYS
- MDW
2 stops10h 05m
Southwest
Mon 10/267:45 am
MDW
- TYS
2 stops8h 00m
Southwest
Deal found 5/20![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/183:42 pm
TYS
- SBN
1 stop17h 07m
Multiple Airlines
Thu 6/259:08 pm
SBN
- TYS
1 stop26h 26m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:15 am
TYS
- ORD
1 stop6h 48m
Delta
Thu 8/65:28 am
ORD
- TYS
1 stop4h 43m
Delta
Deal found 5/17![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:45 pm
TYS
- MDW
2 stops8h 10m
Southwest
Wed 7/89:00 am
MDW
- TYS
1 stop8h 20m
Southwest
Deal found 5/16![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:15 am
TYS
- ORD
1 stop6h 48m
Delta
Thu 8/65:28 am
ORD
- TYS
1 stop4h 43m
Delta
Deal found 5/17![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:35 pm
TYS
- SBN
1 stop7h 09m
United Airlines
Sat 6/133:15 pm
SBN
- TYS
1 stop5h 41m
United Airlines
Deal found 5/18![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:50 pm
TYS
- MDW
2 stops8h 25m
Southwest
Mon 10/267:45 am
MDW
- TYS
2 stops8h 00m
Southwest
Deal found 5/20![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:40 am
TYS
- ORD
1 stop3h 55m
Delta
Thu 8/65:28 am
ORD
- TYS
1 stop4h 43m
Delta
Deal found 5/17![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:15 am
TYS
- ORD
1 stop6h 49m
Delta
Sat 6/136:10 pm
ORD
- TYS
1 stop4h 52m
Delta
Deal found 5/19![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:43 pm
TYS
- AZO
1 stop5h 48m
American Airlines
Fri 6/193:46 pm
AZO
- TYS
2 stops8h 09m
American Airlines
Deal found 5/19![American Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:42 am
TYS
- CVG
1 stop6h 16m
United Airlines
Sun 10/185:30 am
CVG
- TYS
1 stop4h 15m
United Airlines
Deal found 5/18![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:45 pm
TYS
- CVG
1 stop3h 15m
Southwest
Wed 7/17:00 am
CVG
- TYS
2 stops10h 00m
Southwest
Deal found 5/19![Southwest logo]()
$323
Last-minute flights from Knoxville to IndianaDiscover last-minute flight deals from Knoxville to Indiana. Data last updated May 21, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Indiana. Data last updated May 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Fri 6/59:23 pm
MDW
- TYS
1 stop23h 15m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Fri 6/59:23 pm
MDW
- TYS
1 stop23h 15m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Fri 6/59:23 pm
MDW
- TYS
1 stop23h 15m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$180
This Cheapflightsfares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/72:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:22 pm
TYS
- MDW
Nonstop1h 34m
Multiple Airlines
Thu 6/2512:27 pm
MDW
- TYS
2 stops32h 23m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:22 pm
TYS
- MDW
Nonstop1h 34m
Multiple Airlines
Wed 6/1012:04 pm
MDW
- TYS
2 stops31h 26m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$216
This Cheapflightsfares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/142:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Thu 6/182:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/20![Allegiant Air logo]()
$205
This Cheapflightsfares deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/141:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Sun 6/212:46 pm
MDW
- TYS
Nonstop1h 28m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:40 pm
TYS
- CVG
2 stops22h 34m
Multiple Airlines
Mon 6/226:30 am
CVG
- TYS
1 stop16h 13m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:22 pm
TYS
- CVG
1 stop18h 03m
Multiple Airlines
Sun 6/216:10 pm
CVG
- TYS
1 stop28h 33m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:37 am
TYS
- SBN
1 stop6h 29m
American Airlines
Mon 6/227:18 pm
SBN
- TYS
1 stop4h 29m
American Airlines
Deal found 5/19![American Airlines logo]()
$269
One-way flights from Knoxville to IndianaSearch for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
Search for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 5/18![Allegiant Air logo]()
$48
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 5/20![Allegiant Air logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 5/16![Allegiant Air logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/141:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/211:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 5/19![Allegiant Air logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/281:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:11 pm
TYS
- ORD
1 stop16h 14m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:49 pm
TYS
- ORD
2 stops44h 14m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:23 pm
TYS
- SBN
1 stop18h 23m
Allegiant Air
Deal found 5/16![Allegiant Air logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:36 pm
TYS
- ORD
1 stop23h 49m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 pm
TYS
- ORD
2 stops20h 23m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:49 pm
TYS
- MDW
2 stops34h 22m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$122
Find flight deals from Knoxville to Indiana
Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated May 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $174 (Cheapflightsfares) |
One-way from | $48 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $439 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Knoxville to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleCincinnati
TYS - CVG
TYSCVG
Knoxville McGhee Tyson
Mon 6/15
7:22 pm-1:25 pm
1 stop18h 03m
Cincinnati Cinci./N. Kentucky
Sun 6/21
6:10 pm-10:43 pm
1 stop28h 33m
$214
Quickest round-trip
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Fri 6/19
6:00 am-6:59 am
Nonstop1h 59m
Chicago O'Hare Intl
Sat 6/20
6:07 pm-8:56 pm
Nonstop1h 49m
$249
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Wed 6/10
6:00 am-6:59 am
Nonstop1h 59m
Chicago O'Hare Intl
Sat 6/13
6:07 pm-8:56 pm
Nonstop1h 49m
$249
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Sat 6/13
6:00 am-6:59 am
Nonstop1h 59m
Chicago O'Hare Intl
Sat 6/20
6:07 pm-8:56 pm
Nonstop1h 49m
$249
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Thu 6/25
6:00 am-6:59 am
Nonstop1h 59m
Chicago O'Hare Intl
Sun 6/28
7:45 pm-10:34 pm
Nonstop1h 49m
$262
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Wed 10/21
7:30 am-12:33 pm
1 stop6h 03m
Chicago Midway
Mon 10/26
6:00 am-11:06 am
1 stop4h 06m
$269
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Mon 8/3
5:45 am-9:59 am
1 stop5h 14m
Chicago Midway
Sat 8/8
1:27 pm-7:26 pm
1 stop4h 59m
$269
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Tue 7/28
5:40 am-10:05 am
1 stop5h 25m
Chicago Midway
Thu 8/6
6:05 am-11:11 am
1 stop4h 06m
$269
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Tue 6/23
7:15 am-12:46 pm
1 stop6h 31m
Chicago Midway
Tue 6/30
6:00 am-11:09 am
1 stop4h 09m
$269
KnoxvilleSouth Bend
TYS - SBN
TYSSBN
Knoxville McGhee Tyson
Wed 6/24
6:00 am-11:06 am
1 stop5h 06m
South Bend/Michiana
Tue 7/21
9:54 am-2:27 pm
1 stop4h 33m
$269
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
TYS-MDW
TYS-ORD
TYS-SBN
TYS-CVG
TYS-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Indiana
TYS-USIN
TYS-MDW
TYS-ORD
TYS-SBN
TYS-CVG
What is the cheapest month to book a flight from Knoxville to Indiana?
Currently, July is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $31). Flying from Knoxville to Indiana in January is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to IN?
Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 21, 2026.
It’s optimal to fly from Knoxville to Indiana at noon. By choosing this option you can save up to 86% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Knoxville to Indiana?
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 21, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Indiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Indiana
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Complete your trip
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Knoxville and Indiana flights
Browse other Knoxville and Indiana flight options. Last updated on May 21, 2026.
Popular flight searches
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Knoxville to Indiana flights
Consider these flights traveling from Knoxville to Indiana.
Top 4 airlines flying from Knoxville to Indiana
Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$31 | Average$76 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$213 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$273 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$218 | Average$278 | FlexibilityNo cancel fee | On-timeN/A |