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$52+ Cheap flights from Knoxville (TYS) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Knoxville to Indiana

Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated August 14, 2025.

Round-trip from

$80
(Cheapflightsfares)

One-way from

$52
(Kiwi.com)

Popular in

March

Cheapest in

April

Average price

$248

Good round-trip deal

$56 or less

Good one-way deal

$40 or less
From Knoxville McGhee Tyson to Indiana
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One-way flight from Knoxville McGhee Tyson to Indiana
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Highest demand for flights based on searches. 6% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Indiana.
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Price to beat on a one-way flight from Knoxville McGhee Tyson to Indiana.
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Find flight deals from Knoxville to Indiana

Cheapest flights from Knoxville to Indiana
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Mon 9/227:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Deal found 8/12$80
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Mon 9/293:16 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Deal found 8/12$82
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/222:29 pmTYS - MDW
Nonstop1h 33mAllegiant Air
Mon 8/253:52 pmMDW - TYS
Nonstop1h 28mAllegiant Air
Deal found 8/12$86
This Cheapflightsfares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Fri 9/197:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Deal found 8/13$90
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Fri 9/197:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Deal found 8/12$95
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/252:29 pmTYS - MDW
Nonstop1h 33mAllegiant Air
Mon 9/13:52 pmMDW - TYS
Nonstop1h 28mAllegiant Air
Deal found 8/12$103
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Mon 9/227:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Deal found 8/13$107
This Cheapflightsfares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:46 amTYS - MDW
Nonstop1h 32mAllegiant Air
Fri 10/1712:06 pmMDW - TYS
Nonstop1h 24mAllegiant Air
Deal found 8/13$112
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:44 amTYS - MDW
Nonstop1h 32mAllegiant Air
Mon 10/1312:08 pmMDW - TYS
Nonstop1h 24mAllegiant Air
Deal found 8/12$120
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:44 amTYS - MDW
Nonstop1h 32mAllegiant Air
Mon 10/612:08 pmMDW - TYS
Nonstop1h 24mAllegiant Air
Deal found 8/12$130
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/151:31 pmTYS - MDW
Nonstop1h 33mAllegiant Air
Mon 8/182:54 pmMDW - TYS
Nonstop1h 28mAllegiant Air
Deal found 8/12$144
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/289:12 pmTYS - SBN
1 stop14h 47mAllegiant Air
Mon 9/17:50 pmSBN - TYS
Nonstop1h 20mAllegiant Air
Deal found 8/13$174

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Knoxville to Indiana that are best for you.

Fly from

Knoxville

Fly to

Indiana

Route

Depart

Return

Price

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/12

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/15

7:50 pm-10:21 pm

Nonstop1h 31m

$80

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/12

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/22

7:50 pm-10:21 pm

Nonstop1h 31m

$80

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/19

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/22

7:50 pm-10:21 pm

Nonstop1h 31m

$82

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/26

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/29

3:16 pm-5:47 pm

Nonstop1h 31m

$82

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/5

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/8

7:50 pm-10:21 pm

Nonstop1h 31m

$86

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 10/24

1:23 pm-1:55 pm

Nonstop1h 32m

Chicago Midway

Mon 10/27

8:24 pm-10:48 pm

Nonstop1h 24m

$90

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/12

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Fri 9/19

7:50 pm-10:21 pm

Nonstop1h 31m

$90

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 9/15

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Fri 9/19

7:50 pm-10:21 pm

Nonstop1h 31m

$95

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 8/25

2:29 pm-3:02 pm

Nonstop1h 33m

Chicago Midway

Mon 9/1

3:52 pm-6:20 pm

Nonstop1h 28m

$103

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 10/13

10:46 am-11:18 am

Nonstop1h 32m

Chicago Midway

Fri 10/17

12:06 pm-2:30 pm

Nonstop1h 24m

$112

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Indiana

What is the cheapest month to book a flight from Knoxville to Indiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $297). Flying from Knoxville to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IN?

Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Knoxville to Indiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated August 14, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Indiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
702 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Indiana?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Indiana. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Indiana one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $52. Frontier flights start at $82 while deals on American Airlines start at $100 one-way.

  • What are the most popular routes from Knoxville to Indiana?

    When deciding which route to take from Knoxville to Indiana consider Knoxville McGhee Tyson - Chicago O'Hare Intl, Knoxville McGhee Tyson - Chicago Midway or Knoxville McGhee Tyson - Indianapolis as they are the most popular.

  • Can I find deals for flights from Knoxville to Indiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Indiana.

  • Can I find deals for business class flights from Knoxville to Indiana?

    Yes. Cheapflights offers flight deals from Knoxville to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $297). Flying from Knoxville to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Indiana

Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$31Average$76FlexibilityNo cancel feeOn-time88%
DeltaCheapest$208Average$258FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$305FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$278FlexibilityNo cancel feeOn-time69%

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