$105+ Cheap flights from Knoxville (TYS) to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IndianaExplore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:10 am
TYS
- MDW
1 stop6h 50m
Multiple Airlines
Thu 5/282:47 pm
MDW
- TYS
Nonstop1h 26m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
- ORD
1 stop26h 17m
Multiple Airlines
Tue 5/191:27 pm
ORD
- TYS
1 stop27h 32m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$207
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:48 pm
TYS
- ORD
Nonstop2h 09m
American Airlines
Sun 5/105:24 pm
ORD
- TYS
Nonstop1h 54m
American Airlines
Deal found 3/9![American Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- SBN
1 stop12h 27m
Allegiant Air
Sun 4/196:41 pm
SBN
- TYS
1 stop27h 07m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$223
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:40 am
TYS
- ORD
Nonstop2h 08m
American Airlines
Sun 4/58:05 am
ORD
- TYS
Nonstop1h 43m
American Airlines
Deal found 3/8![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:10 am
TYS
- MDW
1 stop6h 50m
Multiple Airlines
Thu 5/212:47 pm
MDW
- TYS
Nonstop1h 26m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:56 pm
TYS
- ORD
1 stop21h 21m
Multiple Airlines
Tue 4/146:08 pm
ORD
- TYS
2 stops44h 33m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 am
TYS
- SBN
1 stop4h 04m
United Airlines
Tue 4/144:45 pm
SBN
- TYS
1 stop5h 58m
United Airlines
Deal found 3/8![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:45 am
TYS
- MDW
1 stop6h 25m
Southwest
Tue 5/123:00 pm
MDW
- TYS
1 stop3h 40m
Southwest
Deal found 3/9![Southwest logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:55 pm
TYS
- ORD
Nonstop1h 55m
United Airlines
Sun 5/107:15 am
ORD
- TYS
Nonstop1h 51m
United Airlines
Deal found 3/10![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
TYS
- MDW
2 stops7h 30m
Southwest
Sat 5/162:15 pm
MDW
- TYS
1 stop3h 15m
Southwest
Deal found 3/9![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:45 am
TYS
- ORD
2 stops8h 45m
Southwest
Sat 5/161:55 pm
ORD
- TYS
1 stop3h 35m
Southwest
Deal found 3/9![Southwest logo]()
$234
Best flights from Knoxville to IndianaDiscover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:57 pm
TYS
- ORD
Nonstop2h 02m
United Airlines
Mon 5/2510:30 am
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 3/8![United Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- SBN
1 stop12h 27m
Allegiant Air
Sun 4/196:41 pm
SBN
- TYS
1 stop27h 07m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$223
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:45 am
TYS
- MDW
1 stop6h 25m
Southwest
Sun 4/126:00 am
MDW
- TYS
1 stop8h 15m
Southwest
Deal found 3/7![Southwest logo]()
$229
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:50 am
TYS
- ORD
1 stop5h 59m
Delta
Mon 4/209:48 am
ORD
- TYS
1 stop6h 20m
Delta
Deal found 3/8![Delta logo]()
$229
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
TYS
- CVG
1 stop4h 25m
American Airlines
Wed 4/227:53 pm
CVG
- TYS
1 stop4h 02m
American Airlines
Deal found 3/8![American Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/232:06 pm
TYS
- CVG
1 stop10h 35m
Multiple Airlines
Tue 3/247:43 pm
CVG
- TYS
2 stops17h 08m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:55 pm
TYS
- SBN
1 stop5h 28m
United Airlines
Fri 5/296:26 pm
SBN
- TYS
1 stop6h 04m
United Airlines
Deal found 3/9![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:50 pm
TYS
- MDW
1 stop5h 25m
Southwest
Wed 4/151:00 pm
MDW
- TYS
1 stop6h 50m
Southwest
Deal found 3/11![Southwest logo]()
$229
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:44 am
TYS
- ORD
1 stop5h 45m
Delta
Mon 5/117:07 am
ORD
- TYS
1 stop6h 26m
Delta
Deal found 3/9![Delta logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:01 pm
TYS
- SBN
1 stop5h 22m
United Airlines
Thu 5/286:26 pm
SBN
- TYS
1 stop6h 04m
United Airlines
Deal found 3/9![United Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:24 pm
TYS
- ORD
1 stop4h 16m
Delta
Sun 5/31:36 pm
ORD
- TYS
1 stop6h 44m
Delta
Deal found 3/8![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 am
TYS
- MDW
1 stop9h 00m
Southwest
Mon 4/612:25 pm
MDW
- TYS
1 stop5h 20m
Southwest
Deal found 3/7![Southwest logo]()
$234
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:00 am
TYS
- ORD
Nonstop1h 55m
United Airlines
Sun 4/197:50 pm
ORD
- TYS
Nonstop1h 44m
United Airlines
Deal found 3/11![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:50 pm
TYS
- MDW
1 stop5h 25m
Southwest
Mon 5/115:30 am
MDW
- TYS
1 stop7h 40m
Southwest
Deal found 3/11![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:30 am
TYS
- SBN
1 stop24h 30m
Allegiant Air
Sun 3/299:10 pm
SBN
- TYS
1 stop26h 22m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$290
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:54 pm
TYS
- MDW
1 stop5h 34m
Delta
Sat 5/99:22 am
MDW
- TYS
1 stop3h 58m
Delta
Deal found 3/12![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:00 am
TYS
- IND
1 stop6h 07m
American Airlines
Sun 5/39:40 am
IND
- TYS
1 stop7h 00m
American Airlines
Deal found 3/8![American Airlines logo]()
$302
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:01 pm
TYS
- ORD
Nonstop1h 54m
United Airlines
Mon 5/186:00 pm
ORD
- TYS
Nonstop1h 45m
United Airlines
Deal found 3/12![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:55 pm
TYS
- MDW
1 stop6h 25m
Southwest
Mon 5/115:30 am
MDW
- TYS
1 stop7h 40m
Southwest
Deal found 3/11![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:05 pm
TYS
- MDW
1 stop4h 28m
Delta
Tue 6/26:23 am
MDW
- TYS
1 stop5h 47m
Delta
Deal found 3/10![Delta logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:15 am
TYS
- IND
1 stop16h 00m
Multiple Airlines
Tue 3/315:08 pm
IND
- TYS
1 stop19h 37m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:00 am
TYS
- ORD
Nonstop1h 56m
United Airlines
Sat 5/236:07 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 3/10![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:45 pm
TYS
- SBN
1 stop7h 32m
Allegiant Air
Sun 4/199:16 pm
SBN
- TYS
1 stop25h 08m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$324
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:25 pm
TYS
- MDW
1 stop5h 40m
Southwest
Thu 4/93:50 pm
MDW
- TYS
1 stop3h 30m
Southwest
Deal found 3/11![Southwest logo]()
$249
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:05 pm
TYS
- ORD
1 stop6h 09m
Delta
Mon 5/187:07 am
ORD
- TYS
1 stop6h 26m
Delta
Deal found 3/9![Delta logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:20 am
TYS
- CVG
1 stop6h 00m
Multiple Airlines
Sun 5/107:43 pm
CVG
- TYS
2 stops21h 47m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:49 am
TYS
- ORD
Nonstop2h 04m
United Airlines
Wed 4/157:15 am
ORD
- TYS
Nonstop1h 53m
United Airlines
Deal found 3/11![United Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:30 pm
TYS
- IND
1 stop5h 41m
American Airlines
Sat 6/1312:11 pm
IND
- TYS
1 stop6h 12m
American Airlines
Deal found 3/7![American Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:05 am
TYS
- MDW
2 stops6h 05m
Southwest
Sun 5/106:00 am
MDW
- TYS
1 stop8h 15m
Southwest
Deal found 3/11![Southwest logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:05 pm
TYS
- CVG
1 stop27h 11m
Allegiant Air
Sun 3/296:01 pm
CVG
- TYS
1 stop14h 22m
Allegiant Air
Deal found 3/10![Allegiant Air logo]()
$343
Last-minute flights from Knoxville to IndianaDiscover last-minute flight deals from Knoxville to Indiana. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Indiana. Data last updated March 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:02 pm
TYS
- ORD
Nonstop2h 02m
American Airlines
Mon 3/231:52 pm
ORD
- TYS
Nonstop1h 39m
American Airlines
Deal found 3/9![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:50 am
TYS
- MDW
2 stops7h 00m
Southwest
Mon 4/612:25 pm
MDW
- TYS
1 stop5h 20m
Southwest
Deal found 3/7![Southwest logo]()
$234
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:02 am
TYS
- SBN
1 stop4h 13m
American Airlines
Mon 4/67:35 pm
SBN
- TYS
1 stop4h 15m
American Airlines
Deal found 3/8![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:30 am
TYS
- MDW
1 stop6h 25m
Southwest
Sat 4/44:35 pm
MDW
- TYS
1 stop3h 30m
Southwest
Deal found 3/11![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 am
TYS
- SBN
1 stop4h 04m
United Airlines
Tue 4/144:45 pm
SBN
- TYS
1 stop5h 58m
United Airlines
Deal found 3/8![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:50 pm
TYS
- MDW
1 stop5h 25m
Southwest
Tue 4/143:00 pm
MDW
- TYS
1 stop3h 40m
Southwest
Deal found 3/10![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:05 am
TYS
- MDW
2 stops6h 05m
Southwest
Sun 4/126:00 am
MDW
- TYS
1 stop8h 15m
Southwest
Deal found 3/11![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:45 pm
TYS
- MDW
2 stops5h 00m
Southwest
Mon 4/135:30 am
MDW
- TYS
1 stop5h 10m
Southwest
Deal found 3/11![Southwest logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- SBN
1 stop12h 27m
Allegiant Air
Sun 4/196:41 pm
SBN
- TYS
1 stop27h 07m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$223
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:05 am
TYS
- MDW
1 stop5h 00m
Southwest
Sun 4/196:00 am
MDW
- TYS
1 stop8h 15m
Southwest
Deal found 3/9![Southwest logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- CVG
2 stops21h 04m
Multiple Airlines
Mon 4/203:47 pm
CVG
- TYS
1 stop6h 37m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:20 pm
TYS
- IND
1 stop15h 29m
Multiple Airlines
Sun 4/197:36 pm
IND
- TYS
1 stop26h 48m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$244
One-way flights from Knoxville to IndianaSearch for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
- ORD
1 stop27h 19m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- ORD
1 stop26h 22m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$110
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:45 pm
TYS
- MDW
1 stop7h 30m
Southwest
Deal found 3/10![Southwest logo]()
$115
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:50 pm
TYS
- ORD
1 stop6h 35m
Southwest
Deal found 3/7![Southwest logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:40 pm
TYS
- ORD
1 stop26h 17m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$116
This CheapOair deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:08 pm
TYS
- ORD
1 stop18h 29m
Frontier
Deal found 3/11![Frontier logo]()
$117
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 am
TYS
- MDW
1 stop9h 00m
Southwest
Deal found 3/11![Southwest logo]()
$120
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 am
TYS
- ORD
1 stop7h 15m
Southwest
Deal found 3/11![Southwest logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:10 am
TYS
- ORD
1 stop5h 32m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:40 am
TYS
- CVG
1 stop7h 32m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:15 pm
TYS
- MDW
2 stops31h 16m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:15 pm
TYS
- ORD
2 stops34h 24m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$124
Find flight deals from Knoxville to Indiana
Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated March 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $207 (Kiwi.com) |
One-way from | $105 (Kiwi.com) |
Popular in | January |
Cheapest in | May |
Average price | $422 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Knoxville to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Sat 5/23
5:57 pm-6:59 pm
Nonstop2h 02m
Chicago O'Hare Intl
Mon 5/25
10:30 am-1:19 pm
Nonstop1h 49m
$209
KnoxvilleSouth Bend
TYS - SBN
TYSSBN
Knoxville McGhee Tyson
Thu 4/16
9:32 pm-9:59 am
1 stop12h 27m
South Bend/Michiana
Sun 4/19
6:41 pm-9:48 pm
1 stop27h 07m
$223
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Sat 4/11
7:45 am-1:10 pm
1 stop6h 25m
Chicago Midway
Sun 4/12
6:00 am-3:15 pm
1 stop8h 15m
$229
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Sat 4/18
7:50 am-12:49 pm
1 stop5h 59m
Chicago O'Hare Intl
Mon 4/20
9:48 am-5:08 pm
1 stop6h 20m
$229
KnoxvilleSouth Bend
TYS - SBN
TYSSBN
Knoxville McGhee Tyson
Sat 5/9
5:55 pm-11:23 pm
1 stop5h 28m
South Bend/Michiana
Fri 5/29
6:26 pm-12:30 am
1 stop6h 04m
$229
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Wed 4/8
5:50 pm-10:15 pm
1 stop5h 25m
Chicago Midway
Wed 4/15
1:00 pm-8:50 pm
1 stop6h 50m
$229
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Fri 5/8
11:44 am-4:29 pm
1 stop5h 45m
Chicago O'Hare Intl
Mon 5/11
7:07 am-2:33 pm
1 stop6h 26m
$229
KnoxvilleSouth Bend
TYS - SBN
TYSSBN
Knoxville McGhee Tyson
Mon 5/11
6:01 pm-11:23 pm
1 stop5h 22m
South Bend/Michiana
Thu 5/28
6:26 pm-12:30 am
1 stop6h 04m
$229
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Fri 5/1
5:24 pm-8:40 pm
1 stop4h 16m
Chicago O'Hare Intl
Sun 5/3
1:36 pm-9:20 pm
1 stop6h 44m
$229
Quickest round-trip
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Thu 4/16
7:00 am-7:55 am
Nonstop1h 55m
Chicago O'Hare Intl
Sun 4/19
7:50 pm-10:34 pm
Nonstop1h 44m
$229
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
TYS-ORD
TYS-MDW
TYS-CVG
TYS-SBN
TYS-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Indiana
TYS-USIN
TYS-ORD
TYS-MDW
TYS-CVG
TYS-SBN
What is the cheapest month to book a flight from Knoxville to Indiana?
Currently, July is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $31). Flying from Knoxville to Indiana in January is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to IN?
Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 12, 2026.
It’s optimal to fly from Knoxville to Indiana at noon. By choosing this option you can save up to 86% on the cost of your flight, compared to a flight in the morning.
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated March 12, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Indiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Indiana
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Complete your trip
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Knoxville and Indiana flights
Browse other Knoxville and Indiana flight options. Last updated on March 12, 2026.
Popular flight searches
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Knoxville to Indiana flights
Consider these flights traveling from Knoxville to Indiana.
Top 4 airlines flying from Knoxville to Indiana
Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$31 | Average$76 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$208 | Average$273 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$208 | Average$258 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$258 | FlexibilityNo cancel fee | On-time71% |