$48+ Cheap flights from Knoxville (TYS) to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
May 25 — Jun 11
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IndianaExplore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:30 am
TYS
- CVG
1 stop7h 05m
Allegiant Air
Sun 7/199:32 pm
CVG
- TYS
1 stop16h 44m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:24 pm
TYS
- ORD
2 stops25h 27m
Multiple Airlines
Sat 6/67:52 pm
ORD
- TYS
1 stop23h 37m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2612:40 pm
TYS
- MDW
2 stops10h 31m
Multiple Airlines
Sun 6/282:46 pm
MDW
- TYS
Nonstop1h 28m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$211
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:05 pm
TYS
- ORD
1 stop6h 09m
Delta
Sat 5/161:44 pm
ORD
- TYS
1 stop6h 41m
Delta
Deal found 4/22![Delta logo]()
$213
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:05 pm
TYS
- MDW
1 stop4h 28m
Delta
Tue 6/26:23 am
MDW
- TYS
1 stop3h 46m
Delta
Deal found 4/21![Delta logo]()
$214
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:30 pm
TYS
- ORD
1 stop5h 56m
Delta
Tue 6/27:07 am
ORD
- TYS
1 stop6h 26m
Delta
Deal found 4/21![Delta logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/281:22 pm
TYS
- MDW
Nonstop1h 34m
Multiple Airlines
Mon 6/296:00 am
MDW
- TYS
2 stops14h 50m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2612:40 pm
TYS
- MDW
2 stops10h 31m
Multiple Airlines
Thu 7/22:48 pm
MDW
- TYS
Nonstop1h 30m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:25 pm
TYS
- SBN
1 stop12h 34m
Allegiant Air
Sun 5/36:41 pm
SBN
- TYS
1 stop27h 07m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:22 pm
TYS
- MDW
Nonstop1h 35m
Multiple Airlines
Sat 5/3011:59 am
MDW
- TYS
3 stops31h 30m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:45 pm
TYS
- MDW
1 stop5h 45m
Southwest
Tue 6/212:50 pm
MDW
- TYS
2 stops7h 00m
Southwest
Deal found 4/22![Southwest logo]()
$220
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:27 am
TYS
- IND
1 stop5h 29m
Delta
Wed 5/2711:20 am
IND
- TYS
1 stop3h 13m
Delta
Deal found 4/20![Delta logo]()
$221
Best flights from Knoxville to IndianaDiscover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
Discover carefully curated flight deals from Knoxville to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:27 am
TYS
- IND
1 stop5h 29m
Delta
Wed 5/2711:20 am
IND
- TYS
1 stop3h 13m
Delta
Deal found 4/20![Delta logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:00 am
TYS
- CVG
1 stop6h 48m
Multiple Airlines
Thu 5/149:30 pm
CVG
- TYS
1 stop24h 54m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:40 pm
TYS
- CVG
1 stop10h 57m
Allegiant Air
Sun 6/73:07 pm
CVG
- TYS
1 stop20h 45m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$242
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:57 pm
TYS
- ORD
Nonstop1h 57m
United Airlines
Sun 8/302:12 pm
ORD
- TYS
Nonstop1h 47m
United Airlines
Deal found 4/23![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:20 pm
TYS
- MDW
1 stop8h 50m
Southwest
Tue 6/165:05 am
MDW
- TYS
1 stop8h 00m
Southwest
Deal found 4/21![Southwest logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:11 pm
TYS
- IND
1 stop5h 19m
American Airlines
Thu 5/712:19 pm
IND
- TYS
1 stop4h 20m
American Airlines
Deal found 4/22![American Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:30 pm
TYS
- ORD
1 stop5h 56m
Delta
Sun 5/247:00 am
ORD
- TYS
1 stop6h 20m
Delta
Deal found 4/20![Delta logo]()
$225
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:55 pm
TYS
- ORD
Nonstop2h 10m
United Airlines
Sun 7/56:45 am
ORD
- TYS
Nonstop1h 48m
United Airlines
Deal found 4/24![United Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:48 pm
TYS
- CVG
1 stop21h 29m
Multiple Airlines
Thu 5/1412:12 pm
CVG
- TYS
2 stops8h 38m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:00 pm
TYS
- ORD
1 stop6h 20m
Delta
Sun 8/307:10 am
ORD
- TYS
1 stop5h 14m
Delta
Deal found 4/23![Delta logo]()
$258
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:45 pm
TYS
- MDW
1 stop3h 10m
Southwest
Sat 6/205:00 am
MDW
- TYS
1 stop8h 05m
Southwest
Deal found 4/24![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:51 am
TYS
- ORD
1 stop3h 38m
Delta
Mon 6/17:07 am
ORD
- TYS
1 stop5h 03m
Delta
Deal found 4/22![Delta logo]()
$266
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:30 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sun 6/285:50 pm
ORD
- TYS
Nonstop1h 49m
United Airlines
Deal found 4/21![United Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:00 am
TYS
- IND
2 stops15h 58m
Multiple Airlines
Sun 5/34:18 pm
IND
- TYS
1 stop4h 56m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:05 pm
TYS
- MDW
1 stop7h 15m
Southwest
Sun 8/306:05 am
MDW
- TYS
1 stop6h 55m
Southwest
Deal found 4/23![Southwest logo]()
$305
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:30 am
TYS
- ORD
Nonstop1h 59m
United Airlines
Sat 6/209:30 pm
ORD
- TYS
Nonstop2h 00m
United Airlines
Deal found 4/24![United Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:56 am
TYS
- SBN
1 stop4h 25m
Delta
Mon 5/256:00 am
SBN
- TYS
1 stop5h 09m
Delta
Deal found 4/22![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:35 pm
TYS
- MDW
2 stops10h 45m
Southwest
Sat 8/157:40 am
MDW
- TYS
2 stops9h 00m
Southwest
Deal found 4/21![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:26 am
TYS
- MDW
1 stop6h 14m
Delta
Wed 7/85:10 pm
MDW
- TYS
1 stop5h 42m
Delta
Deal found 4/24![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:00 am
TYS
- CVG
1 stop9h 58m
Allegiant Air
Wed 5/1312:12 pm
CVG
- TYS
1 stop22h 25m
Allegiant Air
Deal found 4/24![Allegiant Air logo]()
$395
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:11 am
TYS
- MDW
1 stop6h 25m
Delta
Mon 6/299:17 am
MDW
- TYS
1 stop4h 39m
Delta
Deal found 4/23![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:17 pm
TYS
- IND
1 stop12h 09m
Allegiant Air
Sun 6/78:45 am
IND
- TYS
2 stops13h 31m
Allegiant Air
Deal found 4/24![Allegiant Air logo]()
$408
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:45 pm
TYS
- MDW
1 stop5h 30m
Southwest
Mon 7/131:00 pm
MDW
- TYS
2 stops8h 30m
Southwest
Deal found 4/21![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:32 am
TYS
- MDW
1 stop6h 35m
Delta
Tue 7/75:10 pm
MDW
- TYS
1 stop5h 42m
Delta
Deal found 4/25![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:00 am
TYS
- IND
1 stop5h 58m
United Airlines
Mon 5/186:00 am
IND
- TYS
1 stop4h 06m
United Airlines
Deal found 4/22![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:50 pm
TYS
- IND
1 stop10h 55m
Southwest
Wed 5/279:35 am
IND
- TYS
2 stops10h 05m
Southwest
Deal found 4/20![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:05 pm
TYS
- ORD
1 stop5h 03m
Delta
Mon 7/132:07 pm
ORD
- TYS
1 stop6h 31m
Delta
Deal found 4/21![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:00 am
TYS
- CVG
1 stop6h 07m
United Airlines
Mon 5/182:03 pm
CVG
- TYS
1 stop6h 42m
United Airlines
Deal found 4/23![United Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:40 am
TYS
- ORD
1 stop3h 59m
Delta
Sat 8/12:31 pm
ORD
- TYS
1 stop6h 07m
Delta
Deal found 4/20![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:00 am
TYS
- SBN
1 stop5h 31m
United Airlines
Mon 5/113:14 pm
SBN
- TYS
1 stop5h 31m
United Airlines
Deal found 4/23![United Airlines logo]()
$369
Last-minute flights from Knoxville to IndianaDiscover last-minute flight deals from Knoxville to Indiana. Data last updated April 25, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Indiana. Data last updated April 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:25 pm
TYS
- SBN
1 stop12h 34m
Allegiant Air
Sun 5/36:41 pm
SBN
- TYS
1 stop27h 07m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$219
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:30 pm
TYS
- ORD
1 stop5h 56m
Delta
Thu 5/2811:09 am
ORD
- TYS
1 stop5h 18m
Delta
Deal found 4/21![Delta logo]()
$225
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:05 pm
TYS
- ORD
1 stop6h 09m
Delta
Sat 5/161:44 pm
ORD
- TYS
1 stop6h 41m
Delta
Deal found 4/22![Delta logo]()
$213
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:27 am
TYS
- IND
1 stop5h 29m
Delta
Wed 5/2711:20 am
IND
- TYS
1 stop3h 13m
Delta
Deal found 4/20![Delta logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:22 pm
TYS
- MDW
Nonstop1h 35m
Multiple Airlines
Sun 5/246:00 am
MDW
- TYS
3 stops13h 29m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:22 pm
TYS
- MDW
Nonstop1h 35m
Multiple Airlines
Sat 5/3011:59 am
MDW
- TYS
3 stops31h 30m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:45 pm
TYS
- MDW
1 stop5h 45m
Southwest
Sat 5/302:15 pm
MDW
- TYS
1 stop3h 15m
Southwest
Deal found 4/22![Southwest logo]()
$226
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:05 pm
TYS
- MDW
1 stop4h 28m
Delta
Tue 6/26:23 am
MDW
- TYS
1 stop3h 46m
Delta
Deal found 4/21![Delta logo]()
$214
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:30 pm
TYS
- ORD
1 stop5h 56m
Delta
Tue 6/27:07 am
ORD
- TYS
1 stop6h 26m
Delta
Deal found 4/21![Delta logo]()
$214
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:45 pm
TYS
- MDW
1 stop5h 45m
Southwest
Tue 6/212:50 pm
MDW
- TYS
2 stops7h 00m
Southwest
Deal found 4/22![Southwest logo]()
$220
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:05 pm
TYS
- MDW
1 stop4h 28m
Delta
Mon 6/16:23 am
MDW
- TYS
1 stop5h 47m
Delta
Deal found 4/22![Delta logo]()
$230
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:05 pm
TYS
- ORD
1 stop6h 09m
Delta
Mon 6/17:07 am
ORD
- TYS
1 stop6h 26m
Delta
Deal found 4/22![Delta logo]()
$230
One-way flights from Knoxville to IndianaSearch for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
Search for one-way flight options from Knoxville to Indiana. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$48
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:22 pm
TYS
- MDW
Nonstop1h 35m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$52
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:22 pm
TYS
- MDW
Nonstop1h 34m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:22 pm
TYS
- MDW
Nonstop1h 36m
Allegiant Air
Deal found 4/20![Allegiant Air logo]()
$76
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:50 pm
TYS
- ORD
1 stop6h 35m
Southwest
Deal found 4/22![Southwest logo]()
$91
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:59 pm
TYS
- MDW
1 stop4h 10m
Delta
Deal found 4/20![Delta logo]()
$94
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:33 pm
TYS
- ORD
1 stop5h 26m
Delta
Deal found 4/20![Delta logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:27 am
TYS
- ORD
1 stop26h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$99
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:05 am
TYS
- ORD
1 stop6h 45m
Southwest
Deal found 4/23![Southwest logo]()
$100
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:04 pm
TYS
- MDW
Nonstop1h 32m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:40 pm
TYS
- CVG
1 stop10h 57m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 pm
TYS
- MDW
2 stops23h 32m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$108
Find flight deals from Knoxville to Indiana
Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated April 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $200 (Kiwi.com) |
One-way from | $48 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $353 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Knoxville to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Wed 5/20
7:27 am-12:56 pm
1 stop5h 29m
Indianapolis
Wed 5/27
11:20 am-2:33 pm
1 stop3h 13m
$221
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Wed 5/20
3:30 pm-8:26 pm
1 stop5h 56m
Chicago O'Hare Intl
Sun 5/24
7:00 am-2:20 pm
1 stop6h 20m
$225
KnoxvilleCincinnati
TYS - CVG
TYSCVG
Knoxville McGhee Tyson
Mon 5/11
8:00 am-2:48 pm
1 stop6h 48m
Cincinnati Cinci./N. Kentucky
Thu 5/14
9:30 pm-10:24 pm
1 stop24h 54m
$241
KnoxvilleCincinnati
TYS - CVG
TYSCVG
Knoxville McGhee Tyson
Fri 6/5
12:40 pm-11:37 pm
1 stop10h 57m
Cincinnati Cinci./N. Kentucky
Sun 6/7
3:07 pm-11:52 am
1 stop20h 45m
$242
Quickest round-trip
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Fri 8/28
5:57 pm-6:54 pm
Nonstop1h 57m
Chicago O'Hare Intl
Sun 8/30
2:12 pm-4:59 pm
Nonstop1h 47m
$249
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Mon 6/29
5:55 pm-7:05 pm
Nonstop2h 10m
Chicago O'Hare Intl
Sun 7/5
6:45 am-9:33 am
Nonstop1h 48m
$249
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Fri 8/28
4:00 pm-9:20 pm
1 stop6h 20m
Chicago O'Hare Intl
Sun 8/30
7:10 am-1:24 pm
1 stop5h 14m
$258
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Thu 5/28
7:51 am-10:29 am
1 stop3h 38m
Chicago O'Hare Intl
Mon 6/1
7:07 am-1:10 pm
1 stop5h 03m
$266
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Fri 6/12
4:20 pm-12:10 am
1 stop8h 50m
Chicago Midway
Tue 6/16
5:05 am-2:05 pm
1 stop8h 00m
$269
KnoxvilleSouth Bend
TYS - SBN
TYSSBN
Knoxville McGhee Tyson
Thu 5/21
11:56 am-4:21 pm
1 stop4h 25m
South Bend/Michiana
Mon 5/25
6:00 am-11:09 am
1 stop5h 09m
$269
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
TYS-ORD
TYS-MDW
TYS-SBN
TYS-IND
TYS-CVG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Indiana
TYS-USIN
TYS-ORD
TYS-MDW
TYS-SBN
TYS-IND
What is the cheapest month to book a flight from Knoxville to Indiana?
Currently, July is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $31). Flying from Knoxville to Indiana in January is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to IN?
Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2026.
It’s optimal to fly from Knoxville to Indiana at noon. By choosing this option you can save up to 86% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Knoxville to Indiana?
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated April 25, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Indiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Indiana
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Complete your trip
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Knoxville and Indiana flights
Browse other Knoxville and Indiana flight options. Last updated on April 25, 2026.
Popular flight searches
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Knoxville to Indiana flights
Consider these flights traveling from Knoxville to Indiana.
Top 4 airlines flying from Knoxville to Indiana
Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$31 | Average$76 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$208 | Average$263 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$213 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$258 | FlexibilityNo cancel fee | On-time71% |