$122+ Cheap flights from Knoxville (TYS) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Jul 18 — Jul 251
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to LouisianaExplore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:31 pm
TYS
- MSY
1 stop4h 58m
American Airlines
Wed 7/156:53 am
MSY
- TYS
1 stop4h 41m
American Airlines
Deal found 6/15![American Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:55 pm
TYS
- MSY
1 stop5h 25m
Southwest
Wed 7/1510:30 am
MSY
- TYS
2 stops8h 55m
Southwest
Deal found 6/15![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:35 am
TYS
- LFT
1 stop4h 17m
Delta
Wed 7/156:00 am
LFT
- TYS
1 stop6h 16m
Delta
Deal found 6/15![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am
TYS
- MSY
2 stops7h 30m
Southwest
Tue 10/278:00 am
MSY
- TYS
2 stops9h 30m
Southwest
Deal found 6/14![Southwest logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:20 pm
TYS
- MSY
1 stop24h 22m
Multiple Airlines
Fri 7/314:35 pm
MSY
- TYS
1 stop5h 58m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:40 am
TYS
- MSY
1 stop3h 24m
Delta
Wed 7/156:20 am
MSY
- TYS
1 stop5h 56m
Delta
Deal found 6/15![Delta logo]()
$290
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:37 pm
TYS
- BTR
1 stop4h 13m
Delta
Wed 7/156:19 am
BTR
- TYS
1 stop3h 51m
Delta
Deal found 6/15![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:43 pm
TYS
- MSY
1 stop5h 00m
Delta
Tue 7/146:20 am
MSY
- TYS
1 stop3h 50m
Delta
Deal found 6/17![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:20 pm
TYS
- MSY
1 stop20h 31m
Multiple Airlines
Wed 7/155:12 pm
MSY
- TYS
2 stops26h 09m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:55 pm
TYS
- MSY
2 stops9h 05m
Southwest
Mon 8/177:30 am
MSY
- TYS
1 stop4h 55m
Southwest
Deal found 6/17![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:53 pm
TYS
- MSY
2 stops28h 34m
Multiple Airlines
Mon 7/204:45 pm
MSY
- TYS
1 stop5h 48m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:35 am
TYS
- LFT
1 stop4h 17m
Delta
Sun 7/125:03 pm
LFT
- TYS
1 stop5h 49m
Delta
Deal found 6/14![Delta logo]()
$309
Best flights from Knoxville to LouisianaDiscover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
Discover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:35 am
TYS
- LFT
1 stop4h 17m
Delta
Wed 7/156:00 am
LFT
- TYS
1 stop6h 16m
Delta
Deal found 6/15![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:05 pm
TYS
- MSY
2 stops7h 05m
Southwest
Mon 8/317:40 am
MSY
- TYS
1 stop3h 20m
Southwest
Deal found 6/13![Southwest logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:40 pm
TYS
- MSY
2 stops28h 47m
Multiple Airlines
Fri 7/244:35 pm
MSY
- TYS
1 stop5h 58m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:21 pm
TYS
- LFT
1 stop7h 41m
United Airlines
Sat 8/295:20 am
LFT
- TYS
1 stop5h 32m
United Airlines
Deal found 6/17![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:00 pm
TYS
- AEX
2 stops11h 24m
American Airlines
Mon 7/66:00 am
AEX
- TYS
1 stop5h 53m
American Airlines
Deal found 6/17![American Airlines logo]()
$482
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:37 pm
TYS
- BTR
1 stop4h 13m
Delta
Wed 7/156:19 am
BTR
- TYS
1 stop3h 51m
Delta
Deal found 6/15![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:30 pm
TYS
- MSY
2 stops6h 10m
Southwest
Sun 10/255:40 am
MSY
- TYS
1 stop8h 45m
Southwest
Deal found 6/14![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:35 am
TYS
- LFT
1 stop4h 17m
Delta
Sun 7/125:03 pm
LFT
- TYS
1 stop5h 49m
Delta
Deal found 6/14![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:00 pm
TYS
- MSY
2 stops6h 35m
Southwest
Mon 10/2610:50 am
MSY
- TYS
1 stop4h 55m
Southwest
Deal found 6/14![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:15 am
TYS
- MSY
1 stop4h 51m
United Airlines
Wed 8/199:53 am
MSY
- TYS
1 stop7h 24m
United Airlines
Deal found 6/13![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:40 am
TYS
- MSY
1 stop5h 22m
Delta
Mon 9/149:05 am
MSY
- TYS
1 stop5h 20m
Delta
Deal found 6/17![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:55 am
TYS
- MSY
1 stop4h 55m
Southwest
Sun 11/15:10 am
MSY
- TYS
2 stops6h 00m
Southwest
Deal found 6/16![Southwest logo]()
$342
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:40 pm
TYS
- AEX
1 stop5h 20m
United Airlines
Sat 8/224:08 pm
AEX
- TYS
1 stop4h 37m
United Airlines
Deal found 6/17![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:35 am
TYS
- BTR
1 stop6h 12m
Delta
Wed 7/156:19 am
BTR
- TYS
1 stop3h 51m
Delta
Deal found 6/15![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:40 am
TYS
- MSY
2 stops6h 20m
Southwest
Mon 7/201:45 pm
MSY
- TYS
2 stops6h 30m
Southwest
Deal found 6/15![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
TYS
- LFT
2 stops8h 20m
American Airlines
Sun 7/125:36 pm
LFT
- TYS
1 stop5h 15m
American Airlines
Deal found 6/14![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:40 am
TYS
- BTR
1 stop4h 59m
Delta
Wed 7/156:19 am
BTR
- TYS
1 stop5h 57m
Delta
Deal found 6/15![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:21 pm
TYS
- AEX
1 stop6h 39m
United Airlines
Sat 9/54:08 pm
AEX
- TYS
1 stop4h 37m
United Airlines
Deal found 6/16![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:05 pm
TYS
- MSY
2 stops7h 05m
Southwest
Sun 9/205:40 am
MSY
- TYS
2 stops5h 45m
Southwest
Deal found 6/16![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:08 pm
TYS
- LFT
1 stop4h 37m
Delta
Wed 7/1511:37 am
LFT
- TYS
1 stop6h 14m
Delta
Deal found 6/17![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:15 am
TYS
- LFT
1 stop5h 00m
United Airlines
Sat 9/54:04 pm
LFT
- TYS
1 stop4h 41m
United Airlines
Deal found 6/16![United Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:00 am
TYS
- BTR
2 stops8h 45m
American Airlines
Thu 7/96:28 pm
BTR
- TYS
1 stop4h 23m
American Airlines
Deal found 6/16![American Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 am
TYS
- MSY
1 stop3h 36m
Delta
Mon 10/265:30 am
MSY
- TYS
1 stop4h 36m
Delta
Deal found 6/14![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:40 am
TYS
- BTR
1 stop5h 02m
Delta
Wed 7/157:06 pm
BTR
- TYS
1 stop3h 46m
Delta
Deal found 6/15![Delta logo]()
$389
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:35 am
TYS
- BTR
1 stop6h 12m
Delta
Tue 7/147:06 pm
BTR
- TYS
1 stop3h 46m
Delta
Deal found 6/17![Delta logo]()
$391
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:26 am
TYS
- BTR
1 stop5h 43m
Delta
Sun 7/191:27 pm
BTR
- TYS
1 stop5h 38m
Delta
Deal found 6/17![Delta logo]()
$432
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:26 am
TYS
- BTR
1 stop6h 02m
Delta
Tue 7/146:19 am
BTR
- TYS
1 stop3h 51m
Delta
Deal found 6/17![Delta logo]()
$439
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:40 am
TYS
- AEX
1 stop6h 22m
Delta
Mon 7/611:46 am
AEX
- TYS
1 stop4h 29m
Delta
Deal found 6/17![Delta logo]()
$476
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:05 am
TYS
- BTR
1 stop5h 45m
Delta
Sun 10/256:00 am
BTR
- TYS
1 stop4h 06m
Delta
Deal found 6/14![Delta logo]()
$485
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:40 am
TYS
- BTR
1 stop5h 02m
Delta
Sat 7/114:07 pm
BTR
- TYS
1 stop6h 37m
Delta
Deal found 6/13![Delta logo]()
$535
Last-minute flights from Knoxville to LouisianaDiscover last-minute flight deals from Knoxville to Louisiana. Data last updated June 18, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Louisiana. Data last updated June 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:37 pm
TYS
- BTR
1 stop4h 13m
Delta
Wed 7/156:19 am
BTR
- TYS
1 stop3h 51m
Delta
Deal found 6/15![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:31 pm
TYS
- MSY
1 stop4h 58m
American Airlines
Wed 7/156:53 am
MSY
- TYS
1 stop4h 41m
American Airlines
Deal found 6/15![American Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:55 pm
TYS
- MSY
1 stop5h 25m
Southwest
Wed 7/1510:30 am
MSY
- TYS
2 stops8h 55m
Southwest
Deal found 6/15![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:35 am
TYS
- LFT
1 stop4h 17m
Delta
Wed 7/156:00 am
LFT
- TYS
1 stop6h 16m
Delta
Deal found 6/15![Delta logo]()
$285
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:40 am
TYS
- MSY
1 stop3h 24m
Delta
Wed 7/156:20 am
MSY
- TYS
1 stop5h 56m
Delta
Deal found 6/15![Delta logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:20 pm
TYS
- MSY
1 stop20h 31m
Multiple Airlines
Wed 7/155:12 pm
MSY
- TYS
2 stops26h 09m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:35 am
TYS
- BTR
1 stop6h 12m
Delta
Wed 7/156:19 am
BTR
- TYS
1 stop3h 51m
Delta
Deal found 6/15![Delta logo]()
$341
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:43 pm
TYS
- MSY
1 stop5h 00m
Delta
Tue 7/146:20 am
MSY
- TYS
1 stop3h 50m
Delta
Deal found 6/17![Delta logo]()
$293
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:35 am
TYS
- LFT
1 stop4h 17m
Delta
Sun 7/125:03 pm
LFT
- TYS
1 stop5h 49m
Delta
Deal found 6/14![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:38 pm
TYS
- MSY
2 stops25h 49m
Multiple Airlines
Mon 7/204:45 pm
MSY
- TYS
1 stop5h 48m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:53 pm
TYS
- MSY
2 stops28h 34m
Multiple Airlines
Mon 7/204:45 pm
MSY
- TYS
1 stop5h 48m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:20 pm
TYS
- MSY
1 stop24h 22m
Multiple Airlines
Fri 7/314:35 pm
MSY
- TYS
1 stop5h 58m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$289
One-way flights from Knoxville to LouisianaSearch for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
Search for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:50 pm
TYS
- MSY
2 stops30h 12m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$122
This Booking.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:19 pm
TYS
- MSY
1 stop25h 44m
Frontier
Deal found 6/17![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1311:00 am
TYS
- MSY
1 stop8h 53m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- MSY
1 stop18h 22m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:19 pm
TYS
- MSY
2 stops11h 18m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:19 pm
TYS
- MSY
2 stops11h 18m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:50 pm
TYS
- MSY
2 stops28h 37m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$138
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
TYS
- MSY
1 stop7h 55m
United Airlines
Deal found 6/17![United Airlines logo]()
$139
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:30 am
TYS
- BTR
1 stop5h 11m
Delta
Deal found 6/16![Delta logo]()
$204
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:40 am
TYS
- BTR
1 stop4h 59m
Delta
Deal found 6/16![Delta logo]()
$207
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:38 pm
TYS
- BTR
1 stop6h 23m
Delta
Deal found 6/16![Delta logo]()
$220
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/132:30 pm
TYS
- BTR
1 stop5h 00m
Delta
Deal found 6/16![Delta logo]()
$244
Find flight deals from Knoxville to Louisiana
Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated June 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $277 (American Airlines) |
One-way from | $122 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $388 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Tue 7/7
7:35 am-10:52 am
1 stop4h 17m
Lafayette Regional
Wed 7/15
6:00 am-1:16 pm
1 stop6h 16m
$285
Quickest round-trip
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
Sat 7/4
5:37 pm-8:50 pm
1 stop4h 13m
Baton Rouge Ryan
Wed 7/15
6:19 am-11:10 am
1 stop3h 51m
$291
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Wed 7/8
7:35 am-10:52 am
1 stop4h 17m
Lafayette Regional
Sun 7/12
5:03 pm-11:52 pm
1 stop5h 49m
$309
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Thu 8/27
2:05 pm-8:10 pm
2 stops7h 05m
New Orleans Louis Armstrong
Mon 8/31
7:40 am-12:00 pm
1 stop3h 20m
$316
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Wed 10/21
5:30 pm-10:40 pm
2 stops6h 10m
New Orleans Louis Armstrong
Sun 10/25
5:40 am-3:25 pm
1 stop8h 45m
$322
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 7/17
12:40 pm-4:27 pm
2 stops28h 47m
New Orleans Louis Armstrong
Fri 7/24
4:35 pm-11:33 pm
1 stop5h 58m
$331
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 10/23
4:00 pm-9:35 pm
2 stops6h 35m
New Orleans Louis Armstrong
Mon 10/26
10:50 am-4:45 pm
1 stop4h 55m
$335
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 9/11
11:40 am-4:02 pm
1 stop5h 22m
New Orleans Louis Armstrong
Mon 9/14
9:05 am-3:25 pm
1 stop5h 20m
$335
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Wed 8/26
2:21 pm-9:02 pm
1 stop7h 41m
Lafayette Regional
Sat 8/29
5:20 am-11:52 am
1 stop5h 32m
$341
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
Tue 7/7
7:35 am-12:47 pm
1 stop6h 12m
Baton Rouge Ryan
Wed 7/15
6:19 am-11:10 am
1 stop3h 51m
$341
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
TYS-MSY
TYS-LFT
TYS-BTR
TYS-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Louisiana
TYS-USLA
TYS-MSY
TYS-LFT
TYS-BTR
TYS-AEX
What is the cheapest month to book a flight from Knoxville to Louisiana?
Currently, April is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $198). Flying from Knoxville to Louisiana in March is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Louisiana?
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated June 18, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Louisiana
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Complete your trip
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Find flights from Knoxville to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Louisiana flights
Browse other Knoxville and Louisiana flight options. Last updated on June 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Louisiana flights
Consider these flights traveling from Knoxville to Louisiana.
Top 3 airlines flying from Knoxville to Louisiana
Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$294 | Average$376 | FlexibilityNo cancel fee | On-time63% |