$109+ Cheap flights from Knoxville (TYS) to Louisiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Louisiana with Cheapflights
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Cheapest flights from Knoxville to LouisianaExplore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:50 am -
1 stop6h 00m
Fri 11/279:15 am -
1 stop6h 21m
Deal found 11/1![American Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am -
2 stops6h 20m
Tue 12/87:20 am -
1 stop5h 45m
Deal found 11/1![Southwest logo]()
$292
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:15 pm -
2 stops5h 45m
Mon 1/45:10 am -
2 stops6h 00m
Deal found 10/30![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:07 pm -
1 stop5h 20m
Fri 11/276:30 am -
1 stop6h 25m
Deal found 10/30![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:15 pm -
1 stop6h 10m
Fri 1/110:25 am -
1 stop8h 25m
Deal found 10/30![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:40 pm -
2 stops8h 10m
Tue 12/85:40 am -
1 stop7h 25m
Deal found 11/3![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:32 pm -
1 stop5h 08m
Wed 12/96:07 am -
1 stop4h 20m
Deal found 11/4![Delta logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:53 am -
1 stop4h 34m
Sat 12/124:08 pm -
1 stop4h 49m
Deal found 10/30![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:46 pm -
1 stop7h 14m
Sat 12/126:00 am -
1 stop7h 02m
Deal found 11/1![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:15 pm -
1 stop6h 10m
Mon 1/47:45 am -
2 stops6h 15m
Deal found 10/30![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:40 am -
1 stop4h 56m
Tue 12/83:59 pm -
1 stop5h 18m
Deal found 11/3![Delta logo]()
$350
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:04 pm -
1 stop5h 08m
Fri 11/277:35 am -
1 stop5h 29m
Deal found 11/1![American Airlines logo]()
$352
Best flights from Knoxville to LouisianaDiscover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:25 pm -
1 stop6h 40m
Wed 12/169:30 am -
2 stops9h 20m
Deal found 10/31![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:52 pm -
1 stop3h 55m
Sat 12/265:15 am -
1 stop3h 16m
Deal found 10/31![Delta logo]()
$322
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:53 am -
1 stop4h 34m
Sat 12/124:08 pm -
1 stop4h 49m
Deal found 10/30![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:46 pm -
1 stop7h 14m
Sat 12/126:00 am -
1 stop7h 02m
Deal found 11/1![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:15 pm -
2 stops5h 45m
Mon 1/46:50 am -
1 stop7h 10m
Deal found 10/30![Southwest logo]()
$292
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/12:40 pm -
1 stop5h 55m
Fri 2/1212:45 pm -
1 stop8h 30m
Deal found 11/3![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:19 pm -
1 stop6h 28m
Sat 12/265:15 am -
1 stop3h 16m
Deal found 10/31![Delta logo]()
$322
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am -
1 stop5h 21m
Wed 12/92:05 pm -
1 stop6h 52m
Deal found 11/4![United Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:15 pm -
1 stop6h 10m
Fri 1/110:25 am -
1 stop8h 25m
Deal found 10/30![Southwest logo]()
$312
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:05 pm -
1 stop7h 07m
Fri 11/279:44 am -
1 stop5h 56m
Deal found 11/2![American Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
1 stop5h 08m
Tue 11/246:05 am -
1 stop4h 23m
Deal found 11/1![Delta logo]()
$363
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:57 am -
1 stop5h 10m
Fri 12/2512:50 pm -
1 stop5h 59m
Deal found 11/1![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:47 pm -
2 stops8h 09m
Tue 12/85:28 pm -
1 stop5h 12m
Deal found 11/3![American Airlines logo]()
$428
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:15 pm -
1 stop6h 10m
Mon 12/215:20 am -
2 stops5h 45m
Deal found 11/2![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/911:53 am -
1 stop6h 37m
Tue 1/122:00 pm -
1 stop6h 59m
Deal found 11/3![United Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:10 am -
1 stop10h 00m
Fri 12/47:20 am -
1 stop5h 45m
Deal found 10/30![Southwest logo]()
$357
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:15 pm -
2 stops5h 45m
Tue 12/86:40 am -
2 stops6h 25m
Deal found 11/3![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:20 am -
2 stops10h 04m
Wed 12/95:27 pm -
1 stop5h 13m
Deal found 11/4![American Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:53 am -
1 stop6h 38m
Mon 1/112:10 pm -
1 stop6h 49m
Deal found 10/30![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:19 pm -
1 stop4h 54m
Sat 12/266:59 pm -
1 stop15h 32m
Deal found 10/31![Delta logo]()
$537
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
2 stops6h 20m
Sat 12/1911:30 am -
1 stop9h 10m
Deal found 10/31![Southwest logo]()
$387
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:19 pm -
1 stop4h 54m
Sun 12/276:16 am -
1 stop10h 39m
Deal found 10/31![Delta logo]()
$537
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:11 am -
1 stop5h 45m
Sun 12/276:16 am -
1 stop14h 08m
Deal found 10/31![Delta logo]()
$577
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:33 am -
2 stops12h 07m
Fri 11/206:00 pm -
2 stops19h 48m
Deal found 10/30![United Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:40 am -
1 stop5h 32m
Mon 11/3012:41 pm -
1 stop6h 28m
Deal found 11/3![Delta logo]()
$642
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/276:55 am -
1 stop14h 17m
Sat 1/309:15 am -
1 stop24h 57m
Deal found 10/30![United Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:45 am -
2 stops13h 46m
Wed 11/184:03 pm -
1 stop4h 54m
Deal found 10/30![United Airlines logo]()
$693
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:45 pm -
1 stop6h 46m
Sat 11/219:15 am -
1 stop24h 57m
Deal found 11/2![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:45 am -
2 stops14h 12m
Mon 11/3012:00 pm -
1 stop22h 12m
Deal found 11/3![United Airlines logo]()
$882
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop5h 07m
Fri 11/205:54 pm -
2 stops22h 05m
Deal found 11/1![United Airlines logo]()
$982
Last-minute flights from Knoxville to LouisianaDiscover last-minute flight deals from Knoxville to Louisiana. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Louisiana. Data last updated November 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:07 pm -
1 stop5h 20m
Fri 11/276:30 am -
1 stop6h 25m
Deal found 10/30![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:50 am -
1 stop6h 00m
Fri 11/279:15 am -
1 stop6h 21m
Deal found 11/1![American Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:04 pm -
1 stop5h 08m
Fri 11/277:35 am -
1 stop5h 29m
Deal found 11/1![American Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:40 pm -
2 stops8h 10m
Tue 12/85:40 am -
1 stop7h 25m
Deal found 11/3![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:40 am -
1 stop4h 56m
Tue 12/83:59 pm -
1 stop5h 18m
Deal found 11/3![Delta logo]()
$350
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am -
2 stops6h 20m
Tue 12/87:20 am -
1 stop5h 45m
Deal found 11/1![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:32 pm -
1 stop5h 08m
Wed 12/96:07 am -
1 stop4h 20m
Deal found 11/4![Delta logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:53 am -
1 stop4h 34m
Sat 12/124:08 pm -
1 stop4h 49m
Deal found 10/30![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:46 pm -
1 stop7h 14m
Sat 12/126:00 am -
1 stop7h 02m
Deal found 11/1![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:15 pm -
1 stop6h 10m
Fri 1/110:25 am -
1 stop8h 25m
Deal found 10/30![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:15 pm -
1 stop6h 10m
Mon 1/47:45 am -
2 stops6h 15m
Deal found 10/30![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:15 pm -
2 stops5h 45m
Mon 1/45:10 am -
2 stops6h 00m
Deal found 10/30![Southwest logo]()
$297
One-way flights from Knoxville to LouisianaSearch for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:55 pm -
1 stop15h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Allegiant Air logo]()
$109
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:00 pm -
1 stop5h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:58 pm -
2 stops43h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:10 am -
1 stop5h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$168
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:15 pm -
1 stop6h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$169
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:40 am -
1 stop3h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Delta logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:08 pm -
2 stops29h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1612:25 pm -
3 stops27h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$197
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:40 am -
1 stop4h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Delta logo]()
$203
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:04 pm -
1 stop5h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![American Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:04 pm -
1 stop4h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
3 stops26h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Multiple Airlines logo]()
$266
Find flight deals from Knoxville to Louisiana
Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (American Airlines) |
One-way from | $109 (Kiwi.com) |
Popular in | November |
Cheapest in | April |
Average price | $557 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleShreveport
TYS Knoxville McGhee Tyson - SHV Shreveport
TYSSHV
Knoxville McGhee Tyson
Sat 11/14
4:55 pm-7:49 am
1 stop15h 54m
Shreveport
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$109
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Wed 12/16
7:05 am-1:40 pm
2 stops7h 35m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$149
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Mon 11/16
9:10 am-1:42 pm
1 stop5h 32m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$168
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Fri 12/4
5:15 pm-10:25 pm
1 stop6h 10m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$169
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Sun 11/22
5:40 am-8:03 am
1 stop3h 23m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$178
KnoxvilleBaton Rouge
TYS Knoxville McGhee Tyson - BTR Baton Rouge Ryan
TYSBTR
Knoxville McGhee Tyson
Fri 11/20
5:40 am-9:18 am
1 stop4h 38m
Baton Rouge Ryan
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$203
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Sun 11/22
8:04 pm-12:12 am
1 stop5h 08m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$209
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Tue 11/17
7:14 pm-10:59 pm
1 stop4h 45m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$244
KnoxvilleLafayette
TYS Knoxville McGhee Tyson - LFT Lafayette Regional
TYSLFT
Knoxville McGhee Tyson
Wed 11/25
6:10 pm-10:42 pm
1 stop5h 32m
Lafayette Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$289
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Fri 12/11
5:25 pm-11:05 pm
1 stop6h 40m
New Orleans Louis Armstrong
Wed 12/16
9:30 am-7:50 pm
2 stops9h 20m
$292
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
TYS-MSY
TYS-LFT
TYS-SHV
TYS-BTR
TYS-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Louisiana
TYS-USLA
TYS-MSY
TYS-LFT
TYS-SHV
TYS-BTR
What is the cheapest month to book a flight from Knoxville to Louisiana?
Currently, April is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $336). Flying from Knoxville to Louisiana in November is currently the most expensive (average of $557). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Louisiana?
Airfare is below average for this route at the moment.
Knoxville to Louisiana flights typically cost between $406 and $564 in January.The cheapest round-trip price found within the last 5 days was $287 on American Airlines (Jan 4-Jan 12).
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated November 4, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
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Alternative routes for Knoxville to Louisiana
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Complete your trip
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Knoxville and Louisiana flights
Browse other Knoxville and Louisiana flight options. Last updated on November 4, 2026.
Popular flight searches
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Knoxville to Louisiana flights
Consider these flights traveling from Knoxville to Louisiana.
Top 4 airlines flying from Knoxville to Louisiana
Discover the top 4 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$252 | Average$465 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$258 | Average$455 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$377 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$289 | Average$382 | FlexibilityNo cancel fee | On-time63% |