$115+ Cheap flights from Knoxville (TYS) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Sep 2 — Sep 91
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to LouisianaExplore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Sun 8/236:17 pm
MSY
- TYS
1 stop22h 20m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Fri 8/286:17 pm
MSY
- TYS
1 stop24h 45m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- MSY
1 stop18h 22m
Multiple Airlines
Wed 8/1212:36 pm
MSY
- TYS
1 stop28h 00m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Mon 8/318:00 am
MSY
- TYS
1 stop10h 03m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:51 pm
TYS
- MSY
1 stop23h 09m
Multiple Airlines
Thu 8/277:11 pm
MSY
- TYS
2 stops22h 54m
Multiple Airlines
Deal found 8/3![Multiple Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:15 am
TYS
- MSY
1 stop5h 19m
American Airlines
Sat 9/52:02 pm
MSY
- TYS
1 stop6h 48m
American Airlines
Deal found 8/1![American Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:33 am
TYS
- MSY
1 stop14h 22m
Multiple Airlines
Sat 10/245:02 pm
MSY
- TYS
2 stops15h 42m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:00 am
TYS
- MSY
2 stops12h 07m
Multiple Airlines
Sun 9/208:03 pm
MSY
- TYS
1 stop23h 36m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 pm
TYS
- MSY
1 stop5h 30m
Southwest
Mon 10/56:35 am
MSY
- TYS
1 stop5h 35m
Southwest
Deal found 7/30![Southwest logo]()
$293
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:19 am
TYS
- LFT
1 stop7h 22m
American Airlines
Mon 9/75:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:40 am
TYS
- LFT
1 stop6h 20m
Delta
Sun 8/235:10 pm
LFT
- TYS
1 stop3h 50m
Delta
Deal found 7/31![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
TYS
- BTR
1 stop6h 48m
United Airlines
Sun 8/237:15 am
BTR
- TYS
1 stop5h 05m
United Airlines
Deal found 7/31![United Airlines logo]()
$319
Best flights from Knoxville to LouisianaDiscover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
Discover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:25 pm
TYS
- MSY
1 stop5h 30m
Southwest
Sat 10/248:15 am
MSY
- TYS
1 stop7h 30m
Southwest
Deal found 7/30![Southwest logo]()
$287
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:19 am
TYS
- LFT
1 stop7h 22m
American Airlines
Mon 9/75:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:45 pm
TYS
- MSY
1 stop3h 23m
Delta
Mon 9/145:07 pm
MSY
- TYS
1 stop3h 43m
Delta
Deal found 7/30![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:40 pm
TYS
- BTR
1 stop6h 48m
United Airlines
Wed 8/199:35 am
BTR
- TYS
1 stop7h 42m
United Airlines
Deal found 7/31![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:50 am
TYS
- MSY
2 stops7h 10m
Southwest
Sat 9/55:50 am
MSY
- TYS
1 stop6h 25m
Southwest
Deal found 8/1![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:03 am
TYS
- LFT
1 stop5h 12m
American Airlines
Sun 9/65:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:40 am
TYS
- LFT
1 stop6h 20m
Delta
Sun 8/235:10 pm
LFT
- TYS
1 stop3h 50m
Delta
Deal found 7/31![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:50 pm
TYS
- MSY
1 stop6h 35m
Southwest
Mon 11/27:45 am
MSY
- TYS
2 stops6h 15m
Southwest
Deal found 8/1![Southwest logo]()
$318
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:19 am
TYS
- LFT
1 stop7h 22m
American Airlines
Sun 8/305:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:00 am
TYS
- BTR
1 stop5h 04m
United Airlines
Sat 1/94:04 pm
BTR
- TYS
1 stop6h 15m
United Airlines
Deal found 7/31![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:40 am
TYS
- AEX
1 stop6h 36m
Delta
Thu 11/1211:55 am
AEX
- TYS
1 stop5h 31m
Delta
Deal found 8/1![Delta logo]()
$350
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:10 am
TYS
- MSY
1 stop3h 25m
Southwest
Sat 8/297:25 am
MSY
- TYS
2 stops9h 15m
Southwest
Deal found 8/2![Southwest logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:03 am
TYS
- LFT
1 stop5h 12m
American Airlines
Mon 8/175:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:50 am
TYS
- AEX
1 stop5h 52m
Delta
Thu 11/125:27 pm
AEX
- TYS
1 stop5h 30m
Delta
Deal found 8/1![Delta logo]()
$350
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:05 pm
TYS
- MSY
2 stops7h 05m
Southwest
Thu 9/37:30 am
MSY
- TYS
1 stop4h 55m
Southwest
Deal found 7/30![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:12 pm
TYS
- AEX
1 stop4h 29m
Delta
Fri 9/45:07 pm
AEX
- TYS
1 stop5h 45m
Delta
Deal found 7/31![Delta logo]()
$350
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:09 am
TYS
- AEX
1 stop5h 39m
Delta
Thu 11/126:10 am
AEX
- TYS
1 stop4h 19m
Delta
Deal found 8/1![Delta logo]()
$350
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:05 pm
TYS
- MSY
2 stops7h 05m
Southwest
Sat 9/56:30 am
MSY
- TYS
1 stop11h 55m
Southwest
Deal found 8/3![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 am
TYS
- AEX
1 stop9h 15m
United Airlines
Tue 10/274:06 pm
AEX
- TYS
1 stop4h 51m
United Airlines
Deal found 7/31![United Airlines logo]()
$500
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:12 pm
TYS
- BTR
1 stop4h 49m
Delta
Sun 8/2310:26 am
BTR
- TYS
1 stop4h 04m
Delta
Deal found 7/30![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:50 am
TYS
- MSY
2 stops8h 40m
Southwest
Tue 9/2910:20 am
MSY
- TYS
2 stops7h 40m
Southwest
Deal found 8/2![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/125:20 pm
TYS
- LFT
1 stop5h 11m
United Airlines
Sat 1/164:08 pm
LFT
- TYS
2 stops16h 51m
United Airlines
Deal found 8/2![United Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:40 am
TYS
- AEX
2 stops12h 07m
American Airlines
Mon 12/76:00 am
AEX
- TYS
1 stop4h 19m
American Airlines
Deal found 7/29![American Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:34 pm
TYS
- AEX
1 stop5h 12m
Delta
Mon 12/76:10 am
AEX
- TYS
1 stop4h 19m
Delta
Deal found 7/29![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:45 pm
TYS
- MSY
1 stop5h 45m
Southwest
Sun 9/205:40 am
MSY
- TYS
2 stops7h 20m
Southwest
Deal found 7/31![Southwest logo]()
$385
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:21 pm
TYS
- AEX
1 stop26h 09m
United Airlines
Fri 9/44:08 pm
AEX
- TYS
1 stop25h 09m
United Airlines
Deal found 7/31![United Airlines logo]()
$546
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:05 pm
TYS
- MSY
2 stops7h 05m
Southwest
Fri 10/23:20 pm
MSY
- TYS
2 stops6h 20m
Southwest
Deal found 7/30![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:50 am
TYS
- AEX
1 stop10h 52m
Delta
Thu 11/1211:55 am
AEX
- TYS
1 stop5h 31m
Delta
Deal found 8/1![Delta logo]()
$393
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:05 pm
TYS
- MSY
2 stops7h 05m
Southwest
Sun 8/235:40 am
MSY
- TYS
2 stops7h 20m
Southwest
Deal found 7/31![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:06 pm
TYS
- BTR
1 stop3h 58m
Delta
Sun 10/186:00 am
BTR
- TYS
1 stop3h 49m
Delta
Deal found 7/29![Delta logo]()
$408
Last-minute flights from Knoxville to LouisianaDiscover last-minute flight deals from Knoxville to Louisiana. Data last updated August 3, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Louisiana. Data last updated August 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- MSY
1 stop18h 22m
Multiple Airlines
Wed 8/1212:36 pm
MSY
- TYS
1 stop28h 00m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:03 am
TYS
- LFT
1 stop5h 12m
American Airlines
Mon 8/175:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Sun 8/236:17 pm
MSY
- TYS
1 stop22h 20m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Fri 8/286:17 pm
MSY
- TYS
1 stop24h 45m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:51 pm
TYS
- MSY
1 stop23h 09m
Multiple Airlines
Thu 8/277:11 pm
MSY
- TYS
2 stops22h 54m
Multiple Airlines
Deal found 8/3![Multiple Airlines logo]()
$286
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:40 am
TYS
- LFT
1 stop6h 20m
Delta
Sun 8/235:10 pm
LFT
- TYS
1 stop3h 50m
Delta
Deal found 7/31![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
TYS
- BTR
1 stop6h 48m
United Airlines
Sun 8/237:15 am
BTR
- TYS
1 stop5h 05m
United Airlines
Deal found 7/31![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
TYS
- MSY
1 stop3h 19m
Delta
Thu 9/39:05 am
MSY
- TYS
1 stop5h 25m
Delta
Deal found 7/30![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Mon 8/318:00 am
MSY
- TYS
1 stop10h 03m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:00 pm
TYS
- MSY
1 stop7h 48m
United Airlines
Sat 8/295:05 am
MSY
- TYS
1 stop5h 47m
United Airlines
Deal found 8/2![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:08 am
TYS
- LFT
2 stops10h 32m
American Airlines
Sun 8/305:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Deal found 7/29![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:15 am
TYS
- MSY
1 stop5h 19m
American Airlines
Sat 9/52:02 pm
MSY
- TYS
1 stop6h 48m
American Airlines
Deal found 8/1![American Airlines logo]()
$287
One-way flights from Knoxville to LouisianaSearch for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
Search for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:19 pm
TYS
- MSY
2 stops28h 03m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:01 pm
TYS
- MSY
2 stops27h 02m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:55 pm
TYS
- MSY
2 stops30h 07m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:00 am
TYS
- MSY
2 stops10h 32m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am
TYS
- MSY
2 stops10h 02m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$128
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm
TYS
- BTR
1 stop4h 46m
Delta
Deal found 8/3![Delta logo]()
$151
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:28 am
TYS
- BTR
1 stop5h 40m
Delta
Deal found 7/30![Delta logo]()
$200
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:40 am
TYS
- BTR
1 stop4h 59m
Delta
Deal found 8/3![Delta logo]()
$202
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am
TYS
- BTR
1 stop4h 39m
Delta
Deal found 7/30![Delta logo]()
$208
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:06 pm
TYS
- BTR
1 stop6h 06m
Delta
Deal found 7/31![Delta logo]()
$209
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:23 pm
TYS
- BTR
1 stop5h 42m
Delta
Deal found 7/31![Delta logo]()
$215
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:28 am
TYS
- BTR
1 stop5h 40m
Delta
Deal found 7/30![Delta logo]()
$227
Find flight deals from Knoxville to Louisiana
Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated August 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $256 (Kiwi.com) |
One-way from | $115 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $298 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Thu 10/22
7:25 pm-11:55 pm
1 stop5h 30m
New Orleans Louis Armstrong
Sat 10/24
8:15 am-4:45 pm
1 stop7h 30m
$287
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Sat 8/29
6:50 am-1:00 pm
2 stops7h 10m
New Orleans Louis Armstrong
Sat 9/5
5:50 am-1:15 pm
1 stop6h 25m
$292
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Wed 9/2
7:19 am-1:41 pm
1 stop7h 22m
Lafayette Regional
Mon 9/7
5:27 pm-11:18 pm
1 stop4h 51m
$295
Quickest round-trip
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 9/11
5:45 pm-8:08 pm
1 stop3h 23m
New Orleans Louis Armstrong
Mon 9/14
5:07 pm-9:50 pm
1 stop3h 43m
$305
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Thu 10/29
12:50 pm-6:25 pm
1 stop6h 35m
New Orleans Louis Armstrong
Mon 11/2
7:45 am-3:00 pm
2 stops6h 15m
$318
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Fri 9/4
6:03 am-10:15 am
1 stop5h 12m
Lafayette Regional
Sun 9/6
5:27 pm-11:18 pm
1 stop4h 51m
$319
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Fri 8/21
5:40 am-11:00 am
1 stop6h 20m
Lafayette Regional
Sun 8/23
5:10 pm-10:00 pm
1 stop3h 50m
$319
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Fri 8/28
7:19 am-1:41 pm
1 stop7h 22m
Lafayette Regional
Sun 8/30
5:27 pm-11:18 pm
1 stop4h 51m
$319
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 8/28
7:10 am-9:35 am
1 stop3h 25m
New Orleans Louis Armstrong
Sat 8/29
7:25 am-5:40 pm
2 stops9h 15m
$319
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Thu 8/27
2:05 pm-8:10 pm
2 stops7h 05m
New Orleans Louis Armstrong
Thu 9/3
7:30 am-1:25 pm
1 stop4h 55m
$332
Showing 1-10 of 46 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
TYS-MSY
TYS-LFT
TYS-BTR
TYS-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Louisiana
TYS-USLA
TYS-MSY
TYS-LFT
TYS-BTR
TYS-AEX
What is the cheapest month to book a flight from Knoxville to Louisiana?
Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $298). Flying from Knoxville to Louisiana in February is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Louisiana?
Airfare is below average for this route at the moment.
Knoxville to Louisiana flights typically cost between $293 and $668 in August.The cheapest round-trip price found within the last 5 days was $256 on Multiple Airlines (Aug 21-Aug 23).
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated August 3, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Louisiana
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Complete your trip
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Find flights from Knoxville to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Louisiana flights
Browse other Knoxville and Louisiana flight options. Last updated on August 3, 2026.
Popular flight searches
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Knoxville to Louisiana flights
Consider these flights traveling from Knoxville to Louisiana.
Top 3 airlines flying from Knoxville to Louisiana
Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$400 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$384 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$363 | FlexibilityNo cancel fee | On-time63% |