$96+ Cheap flights from Knoxville (TYS) to Louisiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Oct 20 — Oct 271
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Louisiana with Cheapflights
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Cheapest flights from Knoxville to LouisianaExplore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:55 pm -
1 stop5h 45m
Tue 10/137:35 am -
1 stop8h 05m
Deal found 9/15![Southwest logo]()
$196
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:00 pm -
1 stop8h 40m
Wed 10/217:35 am -
1 stop8h 05m
Deal found 9/16![Southwest logo]()
$202
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:00 pm -
1 stop8h 40m
Sat 12/55:45 am -
1 stop7h 25m
Deal found 9/16![Southwest logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:00 am -
1 stop8h 53m
Thu 12/109:40 am -
1 stop9h 51m
Deal found 9/17![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:51 pm -
1 stop24h 48m
Sat 10/176:18 pm -
2 stops22h 03m
Deal found 9/18![Multiple Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:58 pm -
1 stop5h 01m
Sat 10/246:50 pm -
1 stop4h 05m
Deal found 9/19![American Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:23 pm -
1 stop6h 12m
Mon 10/267:22 pm -
1 stop3h 37m
Deal found 9/17![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:35 pm -
1 stop7h 12m
Sat 10/172:16 pm -
1 stop6h 39m
Deal found 9/18![United Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:58 pm -
1 stop5h 01m
Tue 10/273:45 pm -
1 stop6h 33m
Deal found 9/16![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:09 am -
1 stop4h 39m
Sat 10/244:00 pm -
1 stop5h 22m
Deal found 9/19![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:06 pm -
1 stop5h 26m
Sun 10/186:10 am -
1 stop3h 39m
Deal found 9/16![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
1 stop5h 05m
Mon 10/195:27 pm -
1 stop4h 51m
Deal found 9/19![American Airlines logo]()
$339
Best flights from Knoxville to LouisianaDiscover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/178:47 am -
1 stop4h 18m
Sat 2/209:05 am -
1 stop5h 00m
Deal found 9/15![Delta logo]()
$205
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:20 pm -
2 stops7h 45m
Wed 10/217:35 am -
1 stop8h 05m
Deal found 9/16![Southwest logo]()
$239
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:05 pm -
1 stop4h 25m
Sun 10/44:05 pm -
1 stop4h 50m
Deal found 9/15![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:35 pm -
1 stop6h 04m
Wed 10/76:00 am -
1 stop7h 07m
Deal found 9/18![American Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:55 pm -
1 stop5h 45m
Tue 10/137:35 am -
1 stop8h 05m
Deal found 9/19![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:09 am -
1 stop4h 39m
Sat 10/244:00 pm -
1 stop5h 22m
Deal found 9/19![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:15 pm -
2 stops5h 50m
Sat 10/315:40 am -
2 stops8h 50m
Deal found 9/18![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:06 pm -
1 stop5h 26m
Sun 10/186:10 am -
1 stop3h 39m
Deal found 9/15![Delta logo]()
$356
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:00 am -
1 stop5h 15m
Mon 1/112:06 pm -
1 stop7h 08m
Deal found 9/16![United Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:25 pm -
1 stop5h 30m
Sun 11/16:00 am -
2 stops8h 00m
Deal found 9/18![Southwest logo]()
$378
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:45 pm -
1 stop5h 22m
Wed 11/44:06 pm -
1 stop4h 51m
Deal found 9/15![United Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:06 pm -
1 stop4h 56m
Fri 10/232:17 pm -
2 stops8h 38m
Deal found 9/16![American Airlines logo]()
$508
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:00 pm -
1 stop8h 40m
Sun 10/185:20 am -
2 stops5h 50m
Deal found 9/16![Southwest logo]()
$390
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
2 stops11h 47m
Sun 10/185:17 pm -
1 stop5h 01m
Deal found 9/16![American Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:06 pm -
1 stop5h 26m
Sun 10/116:10 am -
1 stop6h 30m
Deal found 9/17![Delta logo]()
$508
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:45 pm -
1 stop6h 52m
Sat 10/1011:46 am -
2 stops32h 03m
Deal found 9/17![United Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:15 am -
2 stops11h 27m
Sun 10/410:56 am -
2 stops9h 57m
Deal found 9/15![American Airlines logo]()
$535
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:45 pm -
2 stops6h 50m
Wed 12/210:40 am -
2 stops8h 10m
Deal found 9/15![Southwest logo]()
$445
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:45 pm -
1 stop6h 58m
Thu 10/298:00 am -
1 stop5h 48m
Deal found 9/19![United Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:04 pm -
1 stop4h 53m
Fri 11/136:15 pm -
1 stop4h 43m
Deal found 9/16![American Airlines logo]()
$573
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:50 pm -
2 stops7h 05m
Sun 10/255:20 am -
2 stops5h 50m
Deal found 9/17![Southwest logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:57 am -
2 stops8h 59m
Sat 10/2410:40 am -
2 stops10h 09m
Deal found 9/19![American Airlines logo]()
$589
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:50 pm -
2 stops7h 05m
Wed 10/141:25 pm -
2 stops6h 40m
Deal found 9/19![Southwest logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:15 am -
1 stop7h 07m
Thu 10/222:10 pm -
2 stops18h 35m
Deal found 9/15![United Airlines logo]()
$640
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 pm -
1 stop5h 30m
Fri 10/91:55 pm -
1 stop6h 40m
Deal found 9/19![Southwest logo]()
$547
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:25 pm -
2 stops18h 57m
Fri 10/234:10 pm -
2 stops21h 32m
Deal found 9/16![United Airlines logo]()
$669
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:15 am -
1 stop6h 54m
Fri 9/254:10 pm -
2 stops16h 35m
Deal found 9/19![United Airlines logo]()
$747
Last-minute flights from Knoxville to LouisianaDiscover last-minute flight deals from Knoxville to Louisiana. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Louisiana. Data last updated September 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:58 pm -
1 stop5h 01m
Tue 10/273:45 pm -
1 stop6h 33m
Deal found 9/16![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:55 pm -
1 stop5h 45m
Tue 10/137:35 am -
1 stop8h 05m
Deal found 9/15![Southwest logo]()
$196
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:00 pm -
1 stop8h 40m
Wed 10/217:35 am -
1 stop8h 05m
Deal found 9/16![Southwest logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:51 pm -
1 stop24h 48m
Sat 10/176:18 pm -
2 stops22h 03m
Deal found 9/18![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:35 pm -
1 stop7h 12m
Sat 10/172:16 pm -
1 stop6h 39m
Deal found 9/18![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:06 pm -
1 stop5h 26m
Sun 10/186:10 am -
1 stop3h 39m
Deal found 9/17![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:06 pm -
1 stop6h 53m
Mon 10/196:50 pm -
1 stop4h 05m
Deal found 9/17![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:58 pm -
1 stop5h 01m
Sat 10/246:50 pm -
1 stop4h 05m
Deal found 9/19![American Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:09 am -
1 stop4h 39m
Sat 10/244:00 pm -
1 stop5h 22m
Deal found 9/19![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
1 stop5h 05m
Mon 10/195:27 pm -
1 stop4h 51m
Deal found 9/19![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:23 pm -
1 stop6h 12m
Mon 10/267:22 pm -
1 stop3h 37m
Deal found 9/17![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:25 pm -
1 stop5h 30m
Mon 11/27:30 am -
1 stop8h 20m
Deal found 9/16![Southwest logo]()
$308
One-way flights from Knoxville to LouisianaSearch for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:50 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$96
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:00 pm -
1 stop3h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$100
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:00 pm -
1 stop8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$101
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:00 pm -
1 stop8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$105
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:23 pm -
1 stop5h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$106
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:25 pm -
1 stop5h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:21 pm -
2 stops26h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$114
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:22 pm -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:17 pm -
2 stops27h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$121
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:40 am -
1 stop4h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$156
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:22 pm -
1 stop3h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$168
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop4h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$171
Find flight deals from Knoxville to Louisiana
Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated September 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $196 (Southwest) |
One-way from | $96 (Southwest) |
Popular in | March |
Cheapest in | November |
Average price | $343 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Wed 10/14
6:23 pm-10:25 pm
1 stop5h 02m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$100
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Wed 12/16
12:32 pm-3:57 pm
1 stop4h 25m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$100
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Wed 10/14
1:00 pm-8:40 pm
1 stop8h 40m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$101
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Wed 12/16
1:00 pm-8:35 pm
1 stop8h 35m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$105
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Tue 10/13
6:23 pm-10:25 pm
1 stop5h 02m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$106
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Thu 10/15
7:25 pm-11:55 pm
1 stop5h 30m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$108
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Mon 10/19
7:45 pm-11:35 pm
1 stop4h 50m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$146
KnoxvilleNew Orleans
TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong
TYSMSY
Knoxville McGhee Tyson
Sat 11/14
6:07 pm-9:37 pm
1 stop4h 30m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$146
KnoxvilleBaton Rouge
TYS Knoxville McGhee Tyson - BTR Baton Rouge Ryan
TYSBTR
Knoxville McGhee Tyson
Sat 11/14
3:45 pm-9:50 pm
1 stop7h 05m
Baton Rouge Ryan
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$156
KnoxvilleBaton Rouge
TYS Knoxville McGhee Tyson - BTR Baton Rouge Ryan
TYSBTR
Knoxville McGhee Tyson
Wed 12/16
8:25 am-1:12 pm
1 stop5h 47m
Baton Rouge Ryan
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$156
Showing 1-10 of 49 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
TYS-MSY
TYS-AEX
TYS-LFT
TYS-BTR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Louisiana
TYS-USLA
TYS-MSY
TYS-AEX
TYS-LFT
TYS-BTR
What is the cheapest month to book a flight from Knoxville to Louisiana?
Currently, November is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $313). Flying from Knoxville to Louisiana in March is currently the most expensive (average of $476). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Louisiana?
Airfare is below average for this route at the moment.
Knoxville to Louisiana flights typically cost between $324 and $456 in October.The cheapest round-trip price found within the last 5 days was $196 on Southwest (Oct 10-Oct 13).
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated September 20, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Louisiana
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Complete your trip
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Search flights from Knoxville to Louisiana by cabin class
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Knoxville and Louisiana flights
Browse other Knoxville and Louisiana flight options. Last updated on September 20, 2026.
Popular flight searches
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Knoxville to Louisiana flights
Consider these flights traveling from Knoxville to Louisiana.
Top 3 airlines flying from Knoxville to Louisiana
Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$410 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$252 | Average$464 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$376 | FlexibilityNo cancel fee | On-time63% |