$112+ Cheap flights from Knoxville (TYS) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
May 28 — Jun 41
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to LouisianaExplore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:20 pm
TYS
- MSY
1 stop22h 05m
Multiple Airlines
Thu 7/165:52 pm
MSY
- TYS
1 stop28h 41m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:20 pm
TYS
- MSY
1 stop16h 47m
Multiple Airlines
Sun 7/195:52 pm
MSY
- TYS
1 stop28h 41m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:00 am
TYS
- MSY
1 stop26h 31m
Multiple Airlines
Tue 6/165:29 pm
MSY
- TYS
1 stop23h 52m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:02 pm
TYS
- MSY
1 stop22h 46m
Multiple Airlines
Sun 5/315:21 pm
MSY
- TYS
2 stops27h 40m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:03 pm
TYS
- MSY
1 stop19h 30m
Multiple Airlines
Tue 5/265:29 pm
MSY
- TYS
1 stop23h 53m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:02 pm
TYS
- MSY
1 stop6h 17m
Multiple Airlines
Thu 6/185:21 pm
MSY
- TYS
2 stops27h 29m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:11 pm
TYS
- MSY
2 stops24h 10m
Multiple Airlines
Tue 6/27:00 am
MSY
- TYS
1 stop8h 15m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:23 pm
TYS
- MSY
1 stop21h 44m
Multiple Airlines
Mon 7/208:00 am
MSY
- TYS
1 stop14h 33m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:55 am
TYS
- MSY
1 stop12h 14m
Multiple Airlines
Sat 11/146:03 pm
MSY
- TYS
1 stop25h 40m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:25 am
TYS
- BTR
1 stop5h 42m
Delta
Tue 5/267:04 pm
BTR
- TYS
1 stop3h 52m
Delta
Deal found 4/26![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:25 pm
TYS
- AEX
1 stop5h 30m
United Airlines
Tue 5/264:00 pm
AEX
- TYS
1 stop6h 12m
United Airlines
Deal found 4/26![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:59 pm
TYS
- LFT
1 stop4h 48m
Delta
Wed 5/205:15 pm
LFT
- TYS
1 stop5h 41m
Delta
Deal found 4/23![Delta logo]()
$329
Best flights from Knoxville to LouisianaDiscover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:50 pm
TYS
- MSY
1 stop3h 35m
Southwest
Tue 5/2610:35 am
MSY
- TYS
2 stops8h 05m
Southwest
Deal found 4/24![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am
TYS
- MSY
1 stop5h 47m
Delta
Mon 9/147:10 pm
MSY
- TYS
1 stop3h 37m
Delta
Deal found 4/23![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:25 pm
TYS
- AEX
1 stop5h 30m
United Airlines
Tue 5/264:00 pm
AEX
- TYS
1 stop6h 12m
United Airlines
Deal found 4/26![United Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
TYS
- LFT
1 stop5h 19m
American Airlines
Tue 9/88:10 am
LFT
- TYS
1 stop6h 47m
American Airlines
Deal found 4/28![American Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:25 am
TYS
- BTR
1 stop5h 42m
Delta
Tue 5/267:04 pm
BTR
- TYS
1 stop3h 52m
Delta
Deal found 4/26![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:55 pm
TYS
- MSY
1 stop7h 05m
Southwest
Thu 9/177:30 am
MSY
- TYS
1 stop4h 55m
Southwest
Deal found 4/27![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:57 pm
TYS
- MSY
1 stop5h 44m
United Airlines
Sat 6/278:00 am
MSY
- TYS
1 stop5h 27m
United Airlines
Deal found 4/26![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:45 pm
TYS
- MSY
2 stops8h 00m
Southwest
Tue 5/2610:35 am
MSY
- TYS
2 stops8h 05m
Southwest
Deal found 4/25![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:20 pm
TYS
- BTR
1 stop3h 38m
Delta
Sun 9/201:40 pm
BTR
- TYS
1 stop3h 37m
Delta
Deal found 4/27![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:40 am
TYS
- MSY
2 stops6h 50m
Southwest
Tue 6/210:40 am
MSY
- TYS
2 stops8h 00m
Southwest
Deal found 4/24![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:40 am
TYS
- MSY
2 stops6h 35m
Southwest
Thu 7/162:30 pm
MSY
- TYS
2 stops5h 40m
Southwest
Deal found 4/25![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:37 am
TYS
- LFT
2 stops8h 56m
American Airlines
Wed 5/137:05 am
LFT
- TYS
1 stop6h 19m
American Airlines
Deal found 4/24![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
TYS
- LFT
1 stop5h 55m
Delta
Wed 5/135:15 pm
LFT
- TYS
1 stop3h 33m
Delta
Deal found 4/24![Delta logo]()
$413
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:30 am
TYS
- MSY
2 stops8h 20m
Southwest
Sun 6/712:30 pm
MSY
- TYS
2 stops7h 45m
Southwest
Deal found 4/27![Southwest logo]()
$367
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:40 am
TYS
- MSY
2 stops6h 35m
Southwest
Wed 7/812:50 pm
MSY
- TYS
2 stops6h 30m
Southwest
Deal found 4/28![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:40 pm
TYS
- AEX
2 stops8h 52m
American Airlines
Wed 6/310:44 am
AEX
- TYS
2 stops12h 15m
American Airlines
Deal found 4/26![American Airlines logo]()
$590
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:30 am
TYS
- LFT
3 stops17h 25m
United Airlines
Tue 9/85:25 am
LFT
- TYS
2 stops17h 32m
United Airlines
Deal found 4/28![United Airlines logo]()
$675
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:54 pm
TYS
- BTR
1 stop4h 57m
American Airlines
Sun 5/174:53 pm
BTR
- TYS
1 stop6h 03m
American Airlines
Deal found 4/28![American Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:08 pm
TYS
- AEX
1 stop4h 17m
Delta
Fri 6/126:05 am
AEX
- TYS
1 stop6h 14m
Delta
Deal found 4/25![Delta logo]()
$604
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:08 pm
TYS
- AEX
1 stop4h 17m
Delta
Fri 6/126:05 am
AEX
- TYS
1 stop4h 04m
Delta
Deal found 4/25![Delta logo]()
$604
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:56 pm
TYS
- AEX
2 stops27h 59m
United Airlines
Fri 6/124:00 pm
AEX
- TYS
1 stop6h 12m
United Airlines
Deal found 4/25![United Airlines logo]()
$764
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:56 pm
TYS
- BTR
2 stops19h 24m
United Airlines
Tue 5/264:09 pm
BTR
- TYS
1 stop6h 03m
United Airlines
Deal found 4/26![United Airlines logo]()
$771
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:00 am
TYS
- LFT
2 stops10h 33m
American Airlines
Wed 5/202:03 pm
LFT
- TYS
2 stops8h 56m
American Airlines
Deal found 4/23![American Airlines logo]()
$819
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:01 pm
TYS
- BTR
2 stops20h 22m
United Airlines
Fri 5/226:09 pm
BTR
- TYS
1 stop22h 58m
United Airlines
Deal found 4/28![United Airlines logo]()
$782
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:35 am
TYS
- BTR
1 stop26h 48m
United Airlines
Sun 5/176:15 pm
BTR
- TYS
2 stops25h 30m
United Airlines
Deal found 4/28![United Airlines logo]()
$881
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:56 pm
TYS
- AEX
2 stops22h 54m
United Airlines
Fri 6/124:00 pm
AEX
- TYS
2 stops20h 19m
United Airlines
Deal found 4/25![United Airlines logo]()
$891
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:57 pm
TYS
- BTR
2 stops18h 20m
United Airlines
Sun 9/206:14 pm
BTR
- TYS
2 stops29h 11m
United Airlines
Deal found 4/27![United Airlines logo]()
$898
Last-minute flights from Knoxville to LouisianaDiscover last-minute flight deals from Knoxville to Louisiana. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Louisiana. Data last updated April 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:02 pm
TYS
- MSY
1 stop22h 46m
Multiple Airlines
Sun 5/315:21 pm
MSY
- TYS
2 stops27h 40m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$258
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:20 pm
TYS
- LFT
1 stop5h 22m
American Airlines
Sat 5/95:42 am
LFT
- TYS
1 stop5h 48m
American Airlines
Deal found 4/24![American Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:25 pm
TYS
- MSY
1 stop23h 23m
Multiple Airlines
Sat 5/95:18 pm
MSY
- TYS
2 stops42h 58m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:56 am
TYS
- MSY
1 stop11h 23m
Multiple Airlines
Sun 5/175:29 pm
MSY
- TYS
1 stop23h 01m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:56 am
TYS
- MSY
2 stops30h 16m
Multiple Airlines
Tue 5/127:00 am
MSY
- TYS
1 stop26h 36m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:59 pm
TYS
- LFT
1 stop4h 48m
Delta
Wed 5/205:15 pm
LFT
- TYS
1 stop5h 41m
Delta
Deal found 4/23![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:50 pm
TYS
- MSY
1 stop3h 35m
Southwest
Tue 5/267:30 am
MSY
- TYS
1 stop3h 30m
Southwest
Deal found 4/24![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:25 am
TYS
- BTR
1 stop5h 42m
Delta
Tue 5/267:04 pm
BTR
- TYS
1 stop3h 52m
Delta
Deal found 4/26![Delta logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:03 pm
TYS
- MSY
1 stop19h 30m
Multiple Airlines
Tue 5/265:29 pm
MSY
- TYS
1 stop23h 53m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$260
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:25 pm
TYS
- AEX
1 stop5h 30m
United Airlines
Tue 5/264:00 pm
AEX
- TYS
1 stop6h 12m
United Airlines
Deal found 4/26![United Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:19 pm
TYS
- MSY
1 stop26h 00m
Multiple Airlines
Sun 5/315:21 pm
MSY
- TYS
2 stops27h 40m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:11 pm
TYS
- MSY
2 stops24h 10m
Multiple Airlines
Tue 6/27:00 am
MSY
- TYS
1 stop8h 15m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$271
One-way flights from Knoxville to LouisianaSearch for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:03 pm
TYS
- MSY
1 stop19h 21m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:26 pm
TYS
- MSY
1 stop16h 41m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:22 pm
TYS
- MSY
1 stop22h 10m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1912:40 pm
TYS
- MSY
2 stops28h 46m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:20 pm
TYS
- MSY
1 stop22h 05m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:01 pm
TYS
- MSY
1 stop20h 48m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:02 pm
TYS
- MSY
2 stops28h 24m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:24 pm
TYS
- MSY
1 stop22h 00m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/259:38 pm
TYS
- MSY
1 stop25h 11m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:01 pm
TYS
- MSY
1 stop10h 18m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$139
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:59 pm
TYS
- BTR
1 stop5h 01m
Delta
Deal found 4/24![Delta logo]()
$216
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:40 am
TYS
- BTR
1 stop5h 05m
Delta
Deal found 4/24![Delta logo]()
$229
Find flight deals from Knoxville to Louisiana
Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Kiwi.com) |
One-way from | $112 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $390 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Tue 5/19
5:50 pm-8:25 pm
1 stop3h 35m
New Orleans Louis Armstrong
Tue 5/26
10:35 am-7:40 pm
2 stops8h 05m
$308
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 9/11
5:30 am-10:17 am
1 stop5h 47m
New Orleans Louis Armstrong
Mon 9/14
7:10 pm-11:47 pm
1 stop3h 37m
$315
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
Thu 5/21
10:25 am-3:07 pm
1 stop5h 42m
Baton Rouge Ryan
Tue 5/26
7:04 pm-11:56 pm
1 stop3h 52m
$317
KnoxvilleAlexandria
TYS - AEX
TYSAEX
Knoxville McGhee Tyson
Sat 5/23
3:25 pm-7:55 pm
1 stop5h 30m
Alexandria
Tue 5/26
4:00 pm-11:12 pm
1 stop6h 12m
$318
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Tue 9/15
1:55 pm-8:00 pm
1 stop7h 05m
New Orleans Louis Armstrong
Thu 9/17
7:30 am-1:25 pm
1 stop4h 55m
$326
KnoxvilleLafayette
TYS - LFT
TYSLFT
Knoxville McGhee Tyson
Tue 9/1
6:00 am-10:19 am
1 stop5h 19m
Lafayette Regional
Tue 9/8
8:10 am-3:57 pm
1 stop6h 47m
$346
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Sat 6/20
5:57 pm-10:41 pm
1 stop5h 44m
New Orleans Louis Armstrong
Sat 6/27
8:00 am-2:27 pm
1 stop5h 27m
$357
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 5/22
2:45 pm-9:45 pm
2 stops8h 00m
New Orleans Louis Armstrong
Tue 5/26
10:35 am-7:40 pm
2 stops8h 05m
$362
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Sat 5/23
6:40 am-12:30 pm
2 stops6h 50m
New Orleans Louis Armstrong
Tue 6/2
10:40 am-7:40 pm
2 stops8h 00m
$362
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
Fri 7/10
6:40 am-12:15 pm
2 stops6h 35m
New Orleans Louis Armstrong
Thu 7/16
2:30 pm-9:10 pm
2 stops5h 40m
$367
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
TYS-MSY
TYS-AEX
TYS-LFT
TYS-BTR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Louisiana
TYS-USLA
TYS-MSY
TYS-AEX
TYS-LFT
TYS-BTR
How far ahead should I book a flight from Knoxville to Louisiana?
The price you pay for your flight from Knoxville to Louisiana may vary depending on when you book. For the best chance of a lower fare, look to book 15 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Knoxville to Louisiana?
Currently, April is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $198). Flying from Knoxville to Louisiana in March is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Louisiana?
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated April 28, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Louisiana
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Complete your trip
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Knoxville and Louisiana flights
Browse other Knoxville and Louisiana flight options. Last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Louisiana flights
Consider these flights traveling from Knoxville to Louisiana.
Top 3 airlines flying from Knoxville to Louisiana
Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$362 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$294 | Average$376 | FlexibilityNo cancel fee | On-time63% |