$86+ Cheap flights from Louisiana to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
May 21 — May 281
Round-trip
1 adult, Economy
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Cheapest flights from Louisiana to KnoxvilleExplore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:38 pm
MSY
- TYS
1 stop18h 20m
Multiple Airlines
Fri 5/81:15 pm
TYS
- MSY
1 stop28h 18m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:00 am
MSY
- TYS
1 stop8h 15m
Multiple Airlines
Tue 6/95:02 pm
TYS
- MSY
1 stop6h 17m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:49 pm
MSY
- TYS
1 stop20h 18m
Multiple Airlines
Sat 6/135:56 pm
TYS
- MSY
1 stop21h 53m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:25 pm
MSY
- TYS
1 stop16h 15m
Multiple Airlines
Tue 5/123:48 pm
TYS
- MSY
1 stop25h 36m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:50 pm
MSY
- TYS
1 stop18h 40m
Multiple Airlines
Sun 5/38:25 pm
TYS
- MSY
1 stop23h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:21 pm
MSY
- TYS
2 stops22h 19m
Multiple Airlines
Mon 6/17:24 pm
TYS
- MSY
1 stop22h 00m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:25 pm
MSY
- TYS
1 stop24h 05m
Multiple Airlines
Mon 5/181:15 pm
TYS
- MSY
1 stop22h 58m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:00 am
MSY
- TYS
1 stop14h 39m
Multiple Airlines
Fri 6/127:22 pm
TYS
- MSY
1 stop20h 27m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:25 pm
MSY
- TYS
1 stop24h 38m
Multiple Airlines
Fri 5/2210:03 pm
TYS
- MSY
1 stop19h 30m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:27 pm
LFT
- TYS
1 stop4h 51m
American Airlines
Mon 8/246:00 am
TYS
- LFT
1 stop5h 19m
American Airlines
Deal found 4/20![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:45 pm
SHV
- TYS
1 stop4h 32m
Delta
Sat 9/265:30 am
TYS
- SHV
1 stop5h 32m
Delta
Deal found 4/17![Delta logo]()
$295
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:27 pm
BTR
- TYS
1 stop5h 24m
American Airlines
Sun 11/225:12 pm
TYS
- BTR
1 stop5h 33m
American Airlines
Deal found 4/20![American Airlines logo]()
$320
Best flights from Louisiana to KnoxvilleDiscover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
Discover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:45 pm
SHV
- TYS
1 stop4h 32m
Delta
Sat 9/265:30 am
TYS
- SHV
1 stop5h 32m
Delta
Deal found 4/17![Delta logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:20 am
MSY
- TYS
2 stops29h 30m
Multiple Airlines
Mon 5/41:15 pm
TYS
- MSY
1 stop5h 51m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:45 am
MSY
- TYS
2 stops9h 45m
Southwest
Mon 5/256:35 am
TYS
- MSY
2 stops6h 10m
Southwest
Deal found 4/17![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:30 pm
LFT
- TYS
1 stop5h 26m
American Airlines
Sat 7/48:11 pm
TYS
- LFT
1 stop4h 46m
American Airlines
Deal found 4/16![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:00 pm
BTR
- TYS
1 stop6h 30m
United Airlines
Wed 9/27:15 am
TYS
- BTR
1 stop7h 00m
United Airlines
Deal found 4/16![United Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:00 pm
BTR
- TYS
1 stop4h 58m
Delta
Sat 8/86:00 am
TYS
- BTR
1 stop4h 39m
Delta
Deal found 4/19![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:50 am
MSY
- TYS
1 stop12h 45m
Southwest
Tue 5/197:05 am
TYS
- MSY
2 stops6h 20m
Southwest
Deal found 4/21![Southwest logo]()
$356
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:16 pm
BTR
- TYS
1 stop4h 40m
American Airlines
Mon 6/15:33 pm
TYS
- BTR
1 stop5h 36m
American Airlines
Deal found 4/18![American Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:27 pm
BTR
- TYS
1 stop5h 45m
Delta
Thu 7/305:40 am
TYS
- BTR
1 stop4h 59m
Delta
Deal found 4/16![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:50 am
MSY
- TYS
2 stops8h 30m
Southwest
Tue 5/127:05 am
TYS
- MSY
2 stops6h 20m
Southwest
Deal found 4/20![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:00 am
SHV
- TYS
1 stop5h 33m
Delta
Wed 6/105:40 am
TYS
- SHV
1 stop5h 08m
Delta
Deal found 4/17![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:05 am
MSY
- TYS
1 stop6h 05m
Southwest
Thu 5/282:45 pm
TYS
- MSY
1 stop7h 15m
Southwest
Deal found 4/17![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:32 pm
BTR
- TYS
1 stop4h 38m
American Airlines
Sun 9/278:39 pm
TYS
- BTR
1 stop4h 07m
American Airlines
Deal found 4/19![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:30 pm
MSY
- TYS
2 stops6h 10m
Southwest
Tue 6/92:45 pm
TYS
- MSY
2 stops8h 55m
Southwest
Deal found 4/18![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:17 pm
MSY
- TYS
1 stop3h 40m
Delta
Sun 6/285:40 am
TYS
- MSY
1 stop3h 28m
Delta
Deal found 4/20![Delta logo]()
$371
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:53 am
SHV
- TYS
2 stops11h 02m
American Airlines
Sat 5/91:20 pm
TYS
- SHV
1 stop5h 40m
American Airlines
Deal found 4/18![American Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:25 pm
MSY
- TYS
1 stop7h 50m
Southwest
Sun 5/317:35 pm
TYS
- MSY
1 stop5h 30m
Southwest
Deal found 4/19![Southwest logo]()
$371
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:35 pm
SHV
- TYS
2 stops8h 12m
American Airlines
Sat 6/135:36 am
TYS
- SHV
1 stop5h 10m
American Airlines
Deal found 4/20![American Airlines logo]()
$455
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:04 pm
BTR
- TYS
1 stop3h 52m
Delta
Sun 5/245:40 am
TYS
- BTR
1 stop5h 05m
Delta
Deal found 4/16![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:30 pm
MSY
- TYS
2 stops5h 40m
Southwest
Sun 6/217:00 pm
TYS
- MSY
1 stop3h 35m
Southwest
Deal found 4/17![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:09 pm
BTR
- TYS
1 stop6h 03m
United Airlines
Mon 6/225:57 pm
TYS
- BTR
2 stops20h 32m
United Airlines
Deal found 4/17![United Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:04 pm
BTR
- TYS
1 stop3h 52m
Delta
Sun 6/75:40 am
TYS
- BTR
1 stop5h 02m
Delta
Deal found 4/19![Delta logo]()
$415
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:30 pm
LFT
- TYS
1 stop5h 26m
American Airlines
Sun 6/285:36 am
TYS
- LFT
1 stop5h 45m
American Airlines
Deal found 4/17![American Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:56 pm
SHV
- TYS
1 stop4h 16m
United Airlines
Wed 6/106:30 am
TYS
- SHV
3 stops17h 14m
United Airlines
Deal found 4/17![United Airlines logo]()
$673
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:11 am
BTR
- TYS
1 stop3h 58m
Delta
Thu 6/185:40 am
TYS
- BTR
1 stop5h 02m
Delta
Deal found 4/20![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:09 pm
BTR
- TYS
2 stops21h 42m
United Airlines
Mon 6/16:30 am
TYS
- BTR
2 stops29h 50m
United Airlines
Deal found 4/18![United Airlines logo]()
$694
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:13 pm
SHV
- TYS
1 stop5h 43m
American Airlines
Sun 5/245:36 am
TYS
- SHV
1 stop4h 53m
American Airlines
Deal found 4/20![American Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:35 pm
SHV
- TYS
1 stop6h 37m
United Airlines
Sat 6/136:30 am
TYS
- SHV
3 stops17h 14m
United Airlines
Deal found 4/17![United Airlines logo]()
$734
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:11 am
BTR
- TYS
1 stop3h 54m
Delta
Sun 7/193:54 pm
TYS
- BTR
1 stop3h 30m
Delta
Deal found 4/19![Delta logo]()
$579
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:00 am
SHV
- TYS
1 stop5h 33m
Delta
Tue 5/265:40 am
TYS
- SHV
1 stop5h 23m
Delta
Deal found 4/20![Delta logo]()
$587
Last-minute flights from Louisiana to KnoxvilleDiscover last-minute flight deals from Louisiana to Knoxville. Data last updated April 21, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Knoxville. Data last updated April 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:50 pm
MSY
- TYS
1 stop18h 40m
Multiple Airlines
Sun 5/38:25 pm
TYS
- MSY
1 stop23h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:04 pm
MSY
- TYS
1 stop19h 59m
Multiple Airlines
Sun 5/312:37 pm
TYS
- MSY
1 stop4h 54m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:39 pm
MSY
- TYS
1 stop27h 56m
Multiple Airlines
Wed 5/64:25 pm
TYS
- MSY
1 stop6h 54m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
SHV
- TYS
1 stop5h 30m
American Airlines
Sat 5/95:57 pm
TYS
- SHV
1 stop6h 00m
American Airlines
Deal found 4/18![American Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:38 pm
MSY
- TYS
1 stop18h 20m
Multiple Airlines
Fri 5/81:15 pm
TYS
- MSY
1 stop28h 18m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:25 pm
MSY
- TYS
1 stop16h 15m
Multiple Airlines
Tue 5/123:48 pm
TYS
- MSY
1 stop25h 36m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$216
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:33 pm
BTR
- TYS
1 stop4h 52m
American Airlines
Sat 5/168:00 am
TYS
- BTR
1 stop4h 31m
American Airlines
Deal found 4/19![American Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:25 pm
MSY
- TYS
1 stop24h 05m
Multiple Airlines
Mon 5/181:15 pm
TYS
- MSY
1 stop22h 58m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:25 pm
MSY
- TYS
1 stop24h 38m
Multiple Airlines
Fri 5/2210:03 pm
TYS
- MSY
1 stop19h 30m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:14 am
BTR
- TYS
1 stop8h 34m
American Airlines
Sat 5/305:36 am
TYS
- BTR
1 stop6h 16m
American Airlines
Deal found 4/17![American Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:21 pm
MSY
- TYS
2 stops22h 19m
Multiple Airlines
Mon 6/17:24 pm
TYS
- MSY
1 stop22h 00m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:25 pm
MSY
- TYS
1 stop6h 12m
Multiple Airlines
Sun 5/311:22 pm
TYS
- MSY
2 stops27h 59m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$258
One-way flights from Louisiana to KnoxvilleSearch for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.
Search for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:38 pm
MSY
- TYS
1 stop18h 20m
Allegiant Air
Deal found 4/17![Allegiant Air logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:50 pm
MSY
- TYS
1 stop18h 40m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:25 pm
MSY
- TYS
1 stop24h 05m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:44 pm
MSY
- TYS
1 stop6h 50m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:13 pm
MSY
- TYS
1 stop20h 17m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:21 pm
MSY
- TYS
2 stops45h 20m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:00 am
MSY
- TYS
1 stop9h 58m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:44 pm
MSY
- TYS
1 stop6h 54m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$114
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:30 am
MSY
- TYS
1 stop6h 00m
American Airlines
Deal found 4/21![American Airlines logo]()
$117
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:04 pm
BTR
- TYS
1 stop3h 52m
Delta
Deal found 4/21![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:11 am
BTR
- TYS
1 stop3h 58m
Delta
Deal found 4/20![Delta logo]()
$229
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:03 am
BTR
- TYS
1 stop6h 07m
Delta
Deal found 4/17![Delta logo]()
$249
Find flight deals from Louisiana to Knoxville
Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated April 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $172 (Kiwi.com) |
One-way from | $86 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $373 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ShreveportKnoxville
SHV - TYS
SHVTYS
Shreveport
Sat 9/19
12:45 pm-6:17 pm
1 stop4h 32m
Knoxville McGhee Tyson
Sat 9/26
5:30 am-10:02 am
1 stop5h 32m
$295
Baton RougeKnoxville
BTR - TYS
BTRTYS
Baton Rouge Ryan
Sun 8/2
4:00 pm-9:58 pm
1 stop4h 58m
Knoxville McGhee Tyson
Sat 8/8
6:00 am-9:39 am
1 stop4h 39m
$321
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Sat 5/2
8:20 am-2:50 pm
2 stops29h 30m
Knoxville McGhee Tyson
Mon 5/4
1:15 pm-6:06 pm
1 stop5h 51m
$341
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Sat 5/23
7:45 am-6:30 pm
2 stops9h 45m
Knoxville McGhee Tyson
Mon 5/25
6:35 am-11:45 am
2 stops6h 10m
$349
Baton RougeKnoxville
BTR - TYS
BTRTYS
Baton Rouge Ryan
Mon 7/13
1:27 pm-8:12 pm
1 stop5h 45m
Knoxville McGhee Tyson
Thu 7/30
5:40 am-9:39 am
1 stop4h 59m
$351
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Sat 5/16
5:50 am-7:35 pm
1 stop12h 45m
Knoxville McGhee Tyson
Tue 5/19
7:05 am-12:25 pm
2 stops6h 20m
$356
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Mon 5/11
10:50 am-8:20 pm
2 stops8h 30m
Knoxville McGhee Tyson
Tue 5/12
7:05 am-12:25 pm
2 stops6h 20m
$357
ShreveportKnoxville
SHV - TYS
SHVTYS
Shreveport
Wed 6/3
8:00 am-2:33 pm
1 stop5h 33m
Knoxville McGhee Tyson
Wed 6/10
5:40 am-9:48 am
1 stop5h 08m
$357
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Mon 5/25
7:05 am-2:10 pm
1 stop6h 05m
Knoxville McGhee Tyson
Thu 5/28
2:45 pm-9:00 pm
1 stop7h 15m
$359
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Tue 6/2
12:30 pm-7:40 pm
2 stops6h 10m
Knoxville McGhee Tyson
Tue 6/9
2:45 pm-10:40 pm
2 stops8h 55m
$367
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Louisiana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
MSY-TYS
BTR-TYS
SHV-TYS
LFT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Knoxville
USLA-TYS
MSY-TYS
BTR-TYS
SHV-TYS
LFT-TYS
What is the cheapest month to book a flight from Louisiana to Knoxville?
Currently, May is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $108). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisiana to Knoxville?
Related info for your journey
Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Louisiana to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisiana to Knoxville by cabin class
Find flights from Louisiana to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 21, 2026.
Louisiana and Knoxville flights
Browse other Louisiana and Knoxville flight options. Last updated on April 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisiana to Knoxville flights
Consider these flights traveling from Louisiana to Knoxville.
Top 3 airlines flying from Louisiana to Knoxville
Discover the top 3 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$405 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$364 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$294 | Average$446 | FlexibilityNo cancel fee | On-time63% |