$96+ Cheap flights from Louisiana to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Cheapest flights from Louisiana to KnoxvilleExplore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:45 pm -
1 stop6h 47m
Sat 11/75:32 pm -
1 stop6h 25m
Deal found 9/14![American Airlines logo]()
$191
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:00 pm -
1 stop5h 05m
Wed 11/45:15 pm -
1 stop6h 10m
Deal found 9/13![Southwest logo]()
$192
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 am -
2 stops9h 20m
Mon 11/165:15 pm -
1 stop6h 10m
Deal found 9/15![Southwest logo]()
$208
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:20 am -
1 stop3h 50m
Mon 11/161:00 pm -
1 stop5h 35m
Deal found 9/14![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:35 am -
1 stop8h 05m
Thu 10/227:25 pm -
1 stop5h 30m
Deal found 9/16![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:21 pm -
1 stop4h 36m
Mon 12/147:28 pm -
1 stop5h 39m
Deal found 9/16![Delta logo]()
$247
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:39 am -
1 stop7h 26m
Sun 11/225:30 am -
1 stop5h 35m
Deal found 9/16![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:20 am -
1 stop3h 40m
Sat 11/216:30 am -
1 stop3h 40m
Deal found 9/13![Southwest logo]()
$280
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:07 pm -
1 stop4h 48m
Tue 10/273:45 pm -
1 stop4h 58m
Deal found 9/16![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:09 pm -
1 stop4h 13m
Sat 10/175:40 am -
1 stop5h 34m
Deal found 9/13![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:03 am -
1 stop6h 28m
Mon 11/95:40 am -
1 stop4h 59m
Deal found 9/17![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:29 pm -
1 stop4h 26m
Wed 10/214:49 pm -
1 stop6h 19m
Deal found 9/15![American Airlines logo]()
$335
Best flights from Louisiana to KnoxvilleDiscover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:21 pm -
1 stop4h 36m
Mon 12/147:28 pm -
1 stop5h 39m
Deal found 9/16![Delta logo]()
$247
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop6h 52m
Sat 10/315:40 pm -
1 stop7h 14m
Deal found 9/16![United Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:30 am -
1 stop5h 30m
Sun 1/102:40 pm -
2 stops8h 10m
Deal found 9/14![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:16 am -
2 stops8h 24m
Sun 12/275:30 am -
1 stop4h 58m
Deal found 9/13![American Airlines logo]()
$498
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:07 pm -
1 stop4h 48m
Tue 10/273:45 pm -
1 stop4h 58m
Deal found 9/16![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:09 pm -
1 stop4h 13m
Sat 10/175:40 am -
1 stop5h 34m
Deal found 9/15![Delta logo]()
$332
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:00 am -
1 stop9h 40m
Sun 12/207:00 am -
2 stops9h 15m
Deal found 9/15![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:30 am -
2 stops9h 15m
Sat 11/77:10 am -
2 stops8h 35m
Deal found 9/13![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
1 stop4h 06m
Fri 1/157:07 am -
1 stop4h 26m
Deal found 9/12![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:25 pm -
2 stops6h 40m
Wed 11/42:40 pm -
2 stops8h 10m
Deal found 9/12![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/32:00 pm -
1 stop7h 14m
Sat 2/65:20 pm -
1 stop5h 16m
Deal found 9/14![United Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:17 pm -
1 stop5h 38m
Sat 10/311:39 am -
1 stop4h 34m
Deal found 9/14![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:08 pm -
1 stop5h 06m
Sat 2/65:38 pm -
1 stop5h 47m
Deal found 9/16![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 am -
2 stops9h 20m
Sun 11/157:05 am -
2 stops7h 25m
Deal found 9/12![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:50 am -
1 stop8h 45m
Wed 10/75:15 pm -
1 stop5h 55m
Deal found 9/14![Southwest logo]()
$396
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/88:10 am -
1 stop4h 50m
Sat 2/132:30 pm -
1 stop7h 15m
Deal found 9/16![Southwest logo]()
$426
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:00 am -
2 stops13h 17m
Wed 2/37:00 am -
1 stop5h 15m
Deal found 9/14![United Airlines logo]()
$555
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:15 pm -
2 stops21h 44m
Mon 11/237:00 am -
1 stop5h 21m
Deal found 9/16![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:15 pm -
2 stops14h 52m
Sun 11/227:00 am -
1 stop5h 21m
Deal found 9/15![United Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:20 am -
2 stops14h 29m
Wed 10/217:15 am -
1 stop7h 05m
Deal found 9/15![United Airlines logo]()
$606
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:55 pm -
1 stop5h 19m
Tue 1/126:15 am -
3 stops16h 16m
Deal found 9/13![United Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:00 am -
2 stops11h 15m
Mon 12/216:30 am -
1 stop5h 53m
Deal found 9/13![United Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am -
2 stops16h 32m
Sun 11/227:00 am -
1 stop5h 21m
Deal found 9/15![United Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:15 pm -
2 stops14h 59m
Thu 12/311:53 am -
1 stop6h 45m
Deal found 9/16![United Airlines logo]()
$696
Last-minute flights from Louisiana to KnoxvilleDiscover last-minute flight deals from Louisiana to Knoxville. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Knoxville. Data last updated September 17, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:09 pm -
1 stop4h 13m
Sat 10/175:40 am -
1 stop5h 34m
Deal found 9/13![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:29 pm -
1 stop4h 26m
Wed 10/214:49 pm -
1 stop6h 19m
Deal found 9/15![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:20 am -
1 stop4h 20m
Wed 10/214:11 pm -
1 stop4h 48m
Deal found 9/14![Delta logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:05 pm -
2 stops47h 16m
Fri 10/238:00 am -
1 stop13h 10m
Deal found 9/16![Multiple Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:07 pm -
1 stop4h 48m
Tue 10/273:45 pm -
1 stop4h 58m
Deal found 9/16![United Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:35 am -
1 stop8h 05m
Thu 10/227:25 pm -
1 stop5h 30m
Deal found 9/16![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:20 am -
1 stop4h 34m
Mon 10/2610:29 am -
1 stop6h 21m
Deal found 9/14![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:06 am -
1 stop7h 30m
Wed 11/47:14 pm -
1 stop4h 45m
Deal found 9/12![American Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:55 am -
1 stop3h 25m
Wed 11/42:40 pm -
2 stops8h 10m
Deal found 9/12![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:00 pm -
1 stop5h 05m
Wed 11/45:15 pm -
1 stop6h 10m
Deal found 9/13![Southwest logo]()
$192
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop6h 52m
Sat 10/315:40 pm -
1 stop7h 14m
Deal found 9/16![United Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops9h 18m
Fri 11/65:30 am -
1 stop4h 57m
Deal found 9/14![American Airlines logo]()
$337
One-way flights from Louisiana to KnoxvilleSearch for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:18 pm -
2 stops14h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$99
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:30 am -
1 stop3h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$100
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:55 am -
2 stops7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:18 pm -
2 stops22h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$103
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/169:30 am -
2 stops9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$105
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:50 am -
1 stop4h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$106
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:40 am -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:08 pm -
2 stops27h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:40 am -
1 stop11h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$115
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am -
1 stop3h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$118
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:49 pm -
1 stop5h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$156
Find flight deals from Louisiana to Knoxville
Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $191 (American Airlines) |
One-way from | $96 (Southwest) |
Popular in | July |
Cheapest in | February |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Mon 11/16
7:30 pm-11:59 pm
1 stop3h 29m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$140
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Tue 3/9
9:05 am-3:05 pm
1 stop5h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$150
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Wed 12/9
6:20 am-1:50 pm
1 stop6h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$150
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Tue 10/13
6:25 am-1:40 pm
1 stop6h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$150
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Wed 11/18
8:00 am-7:36 pm
2 stops10h 36m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$151
Quickest round-trip
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Tue 3/16
1:05 pm-5:13 pm
1 stop3h 08m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$156
Baton RougeKnoxville
BTR Baton Rouge Ryan - TYS Knoxville McGhee Tyson
BTRTYS
Baton Rouge Ryan
Sat 10/17
4:26 pm-10:22 pm
1 stop4h 56m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$156
Baton RougeKnoxville
BTR Baton Rouge Ryan - TYS Knoxville McGhee Tyson
BTRTYS
Baton Rouge Ryan
Sat 11/14
1:38 pm-8:09 pm
1 stop5h 31m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$156
Baton RougeKnoxville
BTR Baton Rouge Ryan - TYS Knoxville McGhee Tyson
BTRTYS
Baton Rouge Ryan
Tue 12/15
1:52 pm-8:14 pm
1 stop5h 22m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$156
Baton RougeKnoxville
BTR Baton Rouge Ryan - TYS Knoxville McGhee Tyson
BTRTYS
Baton Rouge Ryan
Thu 11/12
6:00 am-11:28 am
1 stop4h 28m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$168
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Louisiana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
MSY-TYS
BTR-TYS
SHV-TYS
LFT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Knoxville
USLA-TYS
MSY-TYS
BTR-TYS
SHV-TYS
LFT-TYS
What is the cheapest month to book a flight from Louisiana to Knoxville?
Currently, February is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $364). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $599). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisiana to Knoxville?
Airfare is below average for this route at the moment.
Louisiana to Knoxville flights typically cost between $336 and $466 in November.The cheapest round-trip price found within the last 5 days was $191 on American Airlines (Nov 3-Nov 7).
Related info for your journey
Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Louisiana to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisiana to Knoxville by cabin class
Find flights from Louisiana to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Louisiana and Knoxville flights
Browse other Louisiana and Knoxville flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisiana to Knoxville flights
Consider these flights traveling from Louisiana to Knoxville.
Top 3 airlines flying from Louisiana to Knoxville
Discover the top 3 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$263 | Average$424 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$294 | Average$438 | FlexibilityNo cancel fee | On-time63% |