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Knoxville

$93+ Cheap flights from Louisiana to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Louisiana to Knoxville

Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated July 3, 2025.

Round-trip from

$196
(Mytrip)

One-way from

$93
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$318
From Louisiana to Knoxville McGhee Tyson
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One-way flight from Louisiana to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Louisiana to Knoxville

Cheapest flights from Louisiana to Knoxville
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/318:15 pmMSY - TYS
1 stop12h 56mMultiple Airlines
Sun 8/38:54 pmTYS - MSY
1 stop12h 11mMultiple Airlines
Deal found 7/3$196
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:05 amLFT - TYS
1 stop6h 03mDelta
Wed 8/205:45 amTYS - LFT
1 stop5h 54mDelta
Deal found 7/2$249
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/307:25 amMSY - TYS
1 stop5h 26mDelta
Sat 8/25:30 amTYS - MSY
1 stop4h 54mDelta
Deal found 7/3$249
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:32 pmBTR - TYS
1 stop4h 35mAmerican Airlines
Mon 9/157:45 pmTYS - BTR
1 stop4h 21mAmerican Airlines
Deal found 7/2$249
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/138:16 amLFT - TYS
1 stop5h 59mAmerican Airlines
Wed 8/201:29 pmTYS - LFT
2 stops10h 37mAmerican Airlines
Deal found 7/2$254
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:35 pmMSY - TYS
1 stop4h 46mAmerican Airlines
Sun 9/148:31 pmTYS - MSY
1 stop4h 44mAmerican Airlines
Deal found 7/3$254
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:40 pmBTR - TYS
1 stop3h 33mDelta
Sun 10/265:30 amTYS - BTR
1 stop5h 06mDelta
Deal found 7/2$274
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:25 pmSHV - TYS
1 stop4h 27mAmerican Airlines
Tue 7/292:02 pmTYS - SHV
1 stop4h 53mAmerican Airlines
Deal found 7/3$308
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1912:00 pmSHV - TYS
1 stop6h 53mUnited Airlines
Fri 8/227:20 amTYS - SHV
1 stop4h 51mUnited Airlines
Deal found 6/30$364
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/178:23 amSHV - TYS
1 stop14h 14mMultiple Airlines
Sun 7/208:54 pmTYS - SHV
3 stops25h 20mMultiple Airlines
Deal found 7/2$459
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:45 pmSHV - TYS
1 stop4h 28mDelta
Fri 12/126:10 pmTYS - SHV
1 stop6h 18mDelta
Deal found 7/1$477
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:20 amLFT - TYS
3 stops16h 01mUnited Airlines
Sat 11/297:00 amTYS - LFT
2 stops16h 43mUnited Airlines
Deal found 7/1$800

Cheapflights Fare Finder

Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Louisiana

Fly to

Knoxville

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 7/31

8:15 pm-10:11 am

1 stop12h 56m

Knoxville McGhee Tyson

Sun 8/3

8:54 pm-8:05 am

1 stop12h 11m

$196

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 8/13

5:40 pm-11:48 pm

1 stop5h 08m

Knoxville McGhee Tyson

Wed 8/20

5:45 am-10:39 am

1 stop5h 54m

$249

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 7/25

6:22 pm-11:59 pm

1 stop4h 37m

Knoxville McGhee Tyson

Sun 7/27

8:22 pm-11:59 pm

1 stop4h 37m

$249

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Thu 9/11

6:32 pm-12:07 am

1 stop4h 35m

Knoxville McGhee Tyson

Mon 9/15

7:45 pm-11:06 pm

1 stop4h 21m

$249

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 8/13

8:16 am-3:15 pm

1 stop5h 59m

Knoxville McGhee Tyson

Wed 8/20

1:29 pm-11:06 pm

2 stops10h 37m

$254

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 7/16

6:25 am-11:08 am

1 stop3h 43m

Knoxville McGhee Tyson

Sun 7/20

5:30 am-7:55 am

1 stop3h 25m

$259

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Wed 10/22

1:40 pm-6:13 pm

1 stop3h 33m

Knoxville McGhee Tyson

Sun 10/26

5:30 am-9:36 am

1 stop5h 06m

$274

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Fri 7/25

6:25 pm-11:52 pm

1 stop4h 27m

Knoxville McGhee Tyson

Tue 7/29

2:02 pm-5:55 pm

1 stop4h 53m

$308

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Tue 8/19

12:00 pm-7:53 pm

1 stop6h 53m

Knoxville McGhee Tyson

Fri 8/22

7:20 am-11:11 am

1 stop4h 51m

$364

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Thu 7/17

8:23 am-11:37 pm

1 stop14h 14m

Knoxville McGhee Tyson

Sun 7/20

8:54 pm-9:14 pm

3 stops25h 20m

$459

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 24 results
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Best time to book a flight from Louisiana to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Knoxville

What is the cheapest month to book a flight from Louisiana to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $296). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LA to TYS?

Find hourly flight availability from Louisiana to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from Louisiana to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Louisiana to Knoxville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Louisiana?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Louisiana to Knoxville. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • What are the cheapest airlines to fly from Louisiana to Knoxville one-way?

    One-way options have recently been found by users for as low as $126 on American Airlines. Other airlines that offer cheap prices include Delta from $155 and United Airlines from $311 one-way.

  • What are the most popular routes from Louisiana to Knoxville?

    The most popular route from Louisiana to Knoxville is New Orleans Louis Armstrong - Knoxville McGhee Tyson. You may also consider Baton Rouge Ryan - Knoxville McGhee Tyson or Shreveport - Knoxville McGhee Tyson.

  • Can I find deals for flights from Louisiana to Knoxville that include hotel bookings?

    Yes. In addition to deals on Louisiana to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Knoxville.

  • Can I find deals for business class flights from Louisiana to Knoxville?

    Yes. Cheapflights offers flight deals from Louisiana to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $296). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisiana?

Book flights to Louisiana if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Louisiana to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Knoxville

Discover the top 3 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$104Average$360FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$382FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$216Average$383FlexibilityNo cancel feeOn-time71%

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