$119+ Cheap flights from Indiana to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Nov 25 — Dec 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Indiana to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Indiana to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Indiana to KnoxvilleExplore the most affordable flight options available from Indiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Indiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:20 pm -
1 stop6h 50m
Mon 12/71:58 pm -
2 stops28h 36m
Deal found 10/26![Multiple Airlines logo]()
$222
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:24 pm -
1 stop4h 19m
Thu 11/196:05 pm -
1 stop6h 31m
Deal found 10/22![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:30 am -
1 stop12h 01m
Mon 12/141:58 pm -
2 stops28h 36m
Deal found 10/21![Multiple Airlines logo]()
$241
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:50 am -
1 stop10h 50m
Tue 1/57:55 am -
1 stop4h 10m
Deal found 10/23![Southwest logo]()
$244
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 am -
2 stops14h 05m
Thu 11/197:55 am -
1 stop4h 10m
Deal found 10/22![Southwest logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:20 pm -
1 stop19h 07m
Wed 12/239:49 pm -
1 stop13h 40m
Deal found 10/25![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:39 pm -
1 stop17h 28m
Thu 12/249:08 pm -
1 stop20h 47m
Deal found 10/25![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:31 am -
1 stop7h 15m
Mon 12/71:58 pm -
2 stops28h 36m
Deal found 10/24![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:39 pm -
1 stop17h 28m
Tue 12/229:04 pm -
1 stop13h 46m
Deal found 10/25![Allegiant Air logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:39 pm -
1 stop17h 28m
Wed 12/239:49 pm -
1 stop13h 40m
Deal found 10/25![Allegiant Air logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:15 am -
1 stop25h 52m
Thu 12/109:00 pm -
1 stop13h 25m
Deal found 10/23![Allegiant Air logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:15 am -
1 stop25h 52m
Thu 12/1011:00 am -
2 stops23h 25m
Deal found 10/23![Multiple Airlines logo]()
$311
Best flights from Indiana to KnoxvilleDiscover carefully curated flight deals from Indiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Indiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:47 pm -
1 stop4h 03m
Tue 1/54:00 pm -
1 stop5h 03m
Deal found 10/22![Delta logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2411:25 am -
1 stop22h 22m
Thu 1/289:20 am -
1 stop9h 44m
Deal found 10/26![Allegiant Air logo]()
$249
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:05 pm -
1 stop6h 00m
Wed 12/1611:32 am -
1 stop4h 33m
Deal found 10/25![American Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:33 pm -
1 stop22h 33m
Fri 11/209:13 pm -
1 stop20h 07m
Deal found 10/21![Multiple Airlines logo]()
$288
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:45 am -
2 stops5h 35m
Wed 12/161:00 pm -
1 stop6h 10m
Deal found 10/25![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:33 pm -
1 stop5h 21m
Mon 11/161:55 pm -
1 stop6h 52m
Deal found 10/21![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:18 am -
1 stop4h 55m
Mon 12/216:00 am -
1 stop5h 48m
Deal found 10/25![Delta logo]()
$287
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:54 am -
1 stop5h 32m
Mon 12/288:01 pm -
1 stop4h 30m
Deal found 10/25![American Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:33 pm -
1 stop22h 33m
Thu 11/195:52 pm -
1 stop5h 09m
Deal found 10/21![Allegiant Air logo]()
$325
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:27 pm -
1 stop4h 20m
Thu 12/176:00 am -
1 stop4h 45m
Deal found 10/23![United Airlines logo]()
$329
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:08 pm -
1 stop3h 51m
Thu 11/125:40 am -
1 stop3h 28m
Deal found 10/22![Delta logo]()
$304
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:24 pm -
1 stop6h 23m
Tue 12/87:44 am -
1 stop6h 27m
Deal found 10/25![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:35 am -
1 stop4h 18m
Tue 11/246:45 am -
1 stop4h 09m
Deal found 10/25![United Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:06 pm -
1 stop3h 43m
Sun 11/155:10 pm -
1 stop3h 37m
Deal found 10/22![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop3h 55m
Sat 11/145:40 am -
1 stop6h 45m
Deal found 10/26![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:18 pm -
1 stop6h 29m
Tue 12/18:50 pm -
1 stop4h 22m
Deal found 10/25![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:02 am -
1 stop4h 28m
Mon 11/97:14 pm -
1 stop4h 28m
Deal found 10/21![American Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 pm -
1 stop5h 59m
Thu 11/265:40 am -
1 stop6h 20m
Deal found 10/22![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:47 pm -
1 stop6h 12m
Thu 11/268:50 am -
1 stop4h 24m
Deal found 10/22![American Airlines logo]()
$488
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:02 am -
1 stop5h 25m
Fri 12/259:00 am -
2 stops11h 50m
Deal found 10/26![Delta logo]()
$448
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:02 am -
1 stop3h 59m
Fri 12/259:00 am -
1 stop4h 04m
Deal found 10/26![Delta logo]()
$449
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:14 am -
1 stop6h 31m
Thu 12/106:50 am -
1 stop4h 23m
Deal found 10/21![American Airlines logo]()
$547
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:02 am -
1 stop5h 25m
Thu 12/249:00 am -
2 stops11h 50m
Deal found 10/26![Delta logo]()
$462
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:06 pm -
2 stops9h 53m
Tue 11/247:00 am -
1 stop5h 25m
Deal found 10/25![Delta logo]()
$522
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:36 pm -
1 stop5h 57m
Thu 12/107:00 am -
2 stops7h 56m
Deal found 10/25![Delta logo]()
$591
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:06 pm -
2 stops7h 50m
Fri 11/135:40 am -
2 stops7h 45m
Deal found 10/24![Delta logo]()
$732
Last-minute flights from Indiana to KnoxvilleDiscover last-minute flight deals from Indiana to Knoxville. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to Knoxville. Data last updated October 26, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:08 pm -
1 stop3h 51m
Thu 11/125:40 am -
1 stop3h 28m
Deal found 10/22![Delta logo]()
$304
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:05 am -
1 stop4h 53m
Sun 11/156:48 am -
1 stop5h 20m
Deal found 10/22![American Airlines logo]()
$287
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:33 pm -
1 stop5h 21m
Mon 11/161:55 pm -
1 stop6h 52m
Deal found 10/21![United Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:41 pm -
1 stop7h 56m
Sun 11/156:30 am -
1 stop8h 38m
Deal found 10/24![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:06 pm -
1 stop3h 52m
Sun 11/158:04 pm -
1 stop4h 34m
Deal found 10/22![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:24 pm -
1 stop4h 19m
Thu 11/196:05 pm -
1 stop6h 31m
Deal found 10/22![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 am -
2 stops14h 05m
Thu 11/197:55 am -
1 stop4h 10m
Deal found 10/22![Southwest logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:33 pm -
1 stop22h 33m
Fri 11/209:13 pm -
1 stop20h 07m
Deal found 10/21![Multiple Airlines logo]()
$288
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 am -
2 stops5h 35m
Thu 11/191:00 pm -
1 stop6h 10m
Deal found 10/24![Southwest logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:33 pm -
1 stop22h 33m
Thu 11/195:52 pm -
1 stop5h 09m
Deal found 10/21![Allegiant Air logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:54 am -
1 stop5h 32m
Mon 12/288:01 pm -
1 stop4h 30m
Deal found 10/25![American Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop4h 33m
Mon 11/308:04 pm -
1 stop4h 32m
Deal found 10/25![American Airlines logo]()
$327
One-way flights from Indiana to KnoxvilleSearch for one-way flight options from Indiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Indiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:05 pm -
2 stops25h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$119
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:10 pm -
1 stop5h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$120
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:30 pm -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:30 pm -
2 stops26h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:30 am -
1 stop28h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Allegiant Air logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:18 pm -
1 stop26h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Allegiant Air logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:12 pm -
1 stop18h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Allegiant Air logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/134:42 pm -
1 stop21h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3112:38 pm -
2 stops22h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$184
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:30 pm -
1 stop5h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:30 am -
1 stop5h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Allegiant Air logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:18 pm -
2 stops25h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$211
Find flight deals from Indiana to Knoxville
Keep the following information in mind while searching for Indiana to Knoxville flight deals. Data was last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $239 (American Airlines) |
One-way from | $119 (Kiwi.com) |
Popular in | April |
Cheapest in | December |
Average price | $435 |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Indiana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IndianapolisKnoxville
IND Indianapolis - TYS Knoxville McGhee Tyson
INDTYS
Indianapolis
Tue 11/17
1:10 pm-6:46 pm
1 stop5h 36m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
Quickest round-trip
IndianapolisKnoxville
IND Indianapolis - TYS Knoxville McGhee Tyson
INDTYS
Indianapolis
Fri 11/13
5:30 pm-9:45 pm
1 stop4h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$123
IndianapolisKnoxville
IND Indianapolis - TYS Knoxville McGhee Tyson
INDTYS
Indianapolis
Thu 10/29
7:30 am-12:07 pm
1 stop28h 37m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$135
EvansvilleKnoxville
EVV Evansville Dress Regional - TYS Knoxville McGhee Tyson
EVVTYS
Evansville Dress Regional
Sun 12/20
8:18 pm-11:22 pm
1 stop26h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$161
South BendKnoxville
SBN South Bend/Michiana - TYS Knoxville McGhee Tyson
SBNTYS
South Bend/Michiana
Wed 11/25
9:12 pm-3:42 pm
1 stop18h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$175
EvansvilleKnoxville
EVV Evansville Dress Regional - TYS Knoxville McGhee Tyson
EVVTYS
Evansville Dress Regional
Wed 1/13
4:42 pm-2:57 pm
1 stop21h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$183
IndianapolisKnoxville
IND Indianapolis - TYS Knoxville McGhee Tyson
INDTYS
Indianapolis
Mon 12/14
6:30 pm-11:57 pm
1 stop5h 27m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$185
IndianapolisKnoxville
IND Indianapolis - TYS Knoxville McGhee Tyson
INDTYS
Indianapolis
Sat 11/21
7:30 pm-10:04 pm
3 stops26h 34m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$211
EvansvilleKnoxville
EVV Evansville Dress Regional - TYS Knoxville McGhee Tyson
EVVTYS
Evansville Dress Regional
Sun 12/20
8:18 pm-10:40 pm
2 stops25h 22m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$211
IndianapolisKnoxville
IND Indianapolis - TYS Knoxville McGhee Tyson
INDTYS
Indianapolis
Wed 12/23
7:47 pm-11:50 pm
1 stop4h 03m
Knoxville McGhee Tyson
Tue 1/5
4:00 pm-9:03 pm
1 stop5h 03m
$239
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Indiana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indiana with our price prediction graph.
IND-TYS
FWA-TYS
SBN-TYS
EVV-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to Knoxville
USIN-TYS
IND-TYS
FWA-TYS
SBN-TYS
EVV-TYS
What is the cheapest month to book a flight from Indiana to Knoxville?
Currently, November is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $173). Flying from Indiana to Knoxville in January is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Indiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Indiana to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to Knoxville by cabin class
Find flights from Indiana to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
Indiana and Knoxville flights
Browse other Indiana and Knoxville flight options. Last updated on October 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Indiana to Knoxville flights
Consider these flights traveling from Indiana to Knoxville.
Top 3 airlines flying from Indiana to Knoxville
Discover the top 3 airlines that operate flights from Indiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$361 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$217 | Average$383 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$373 | FlexibilityNo cancel fee | On-timeN/A |