$339+ Cheap flights from Florence, SC (FLO) to Houston
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — HOU
Oct 11 — Oct 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Florence to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Houston
Cheapest
Best
Last-minute
Cheapest flights from Florence to HoustonExplore the most affordable flight options available from Florence to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Florence to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:19 pm -
1 stop7h 45m
Tue 10/136:12 am -
1 stop7h 42m
Deal found 9/7![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:24 am -
1 stop4h 40m
Wed 9/306:50 am -
1 stop5h 28m
Deal found 9/11![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:09 am -
1 stop4h 49m
Mon 10/125:51 pm -
1 stop5h 06m
Deal found 9/7![American Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:30 am -
2 stops11h 06m
Tue 10/139:51 am -
2 stops12h 21m
Deal found 9/7![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:09 am -
2 stops12h 22m
Tue 11/109:11 am -
2 stops12h 48m
Deal found 9/7![American Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:24 am -
2 stops10h 19m
Wed 9/3011:31 am -
2 stops10h 27m
Deal found 9/10![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:09 am -
2 stops9h 28m
Tue 11/106:00 am -
2 stops8h 16m
Deal found 9/7![American Airlines logo]()
$809
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:43 pm -
1 stop6h 41m
Thu 9/106:50 am -
1 stop5h 28m
Deal found 9/9![American Airlines logo]()
$897
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:43 pm -
2 stops20h 13m
Thu 9/1011:31 am -
2 stops10h 27m
Deal found 9/9![American Airlines logo]()
$1,178
Best flights from Florence to HoustonDiscover carefully curated flight deals from Florence to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Florence to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:09 am -
1 stop4h 54m
Tue 11/107:25 am -
1 stop6h 51m
Deal found 9/7![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:19 pm -
1 stop7h 45m
Tue 10/136:12 am -
1 stop7h 42m
Deal found 9/7![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:24 am -
2 stops13h 01m
Wed 9/304:16 pm -
1 stop5h 42m
Deal found 9/11![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:34 pm -
1 stop6h 47m
Mon 10/1211:55 am -
2 stops11h 02m
Deal found 9/7![American Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:30 am -
2 stops11h 06m
Tue 10/139:51 am -
2 stops12h 21m
Deal found 9/7![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:24 am -
2 stops10h 19m
Wed 9/3011:31 am -
2 stops10h 27m
Deal found 9/10![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:09 am -
2 stops9h 28m
Tue 11/106:00 am -
2 stops8h 16m
Deal found 9/7![American Airlines logo]()
$809
Last-minute flights from Florence to HoustonDiscover last-minute flight deals from Florence to Houston. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Houston. Data last updated September 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:24 am -
1 stop4h 40m
Wed 9/306:50 am -
1 stop5h 28m
Deal found 9/11![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:24 am -
2 stops10h 19m
Wed 9/3011:31 am -
2 stops10h 27m
Deal found 9/10![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:09 am -
1 stop4h 49m
Mon 10/125:51 pm -
1 stop5h 06m
Deal found 9/7![American Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:19 pm -
1 stop7h 45m
Tue 10/136:12 am -
1 stop7h 42m
Deal found 9/7![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:30 am -
2 stops11h 06m
Tue 10/139:51 am -
2 stops12h 21m
Deal found 9/7![American Airlines logo]()
$691
Find flight deals from Florence to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Round-trip from | $339 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Florence to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
FlorenceHouston
FLO Florence - IAH Houston George Bush Intcntl
FLOIAH
Florence
Sun 11/1
5:09 am-9:03 am
1 stop4h 54m
Houston George Bush Intcntl
Tue 11/10
7:25 am-3:16 pm
1 stop6h 51m
$339
FlorenceHouston
FLO Florence - IAH Houston George Bush Intcntl
FLOIAH
Florence
Tue 10/6
3:19 pm-10:04 pm
1 stop7h 45m
Houston George Bush Intcntl
Tue 10/13
6:12 am-2:54 pm
1 stop7h 42m
$339
FlorenceHouston
FLO Florence - IAH Houston George Bush Intcntl
FLOIAH
Florence
Sat 9/26
6:24 am-6:25 pm
2 stops13h 01m
Houston George Bush Intcntl
Wed 9/30
4:16 pm-10:58 pm
1 stop5h 42m
$606
FlorenceHouston
FLO Florence - IAH Houston George Bush Intcntl
FLOIAH
Florence
Mon 10/5
2:34 pm-8:21 pm
1 stop6h 47m
Houston George Bush Intcntl
Mon 10/12
11:55 am-11:57 pm
2 stops11h 02m
$623
FlorenceHouston
FLO Florence - HOU Houston Hobby
FLOHOU
Florence
Tue 10/6
6:30 am-4:36 pm
2 stops11h 06m
Houston Hobby
Tue 10/13
9:51 am-11:12 pm
2 stops12h 21m
$691
FlorenceHouston
FLO Florence - HOU Houston Hobby
FLOHOU
Florence
Sat 9/26
6:24 am-3:43 pm
2 stops10h 19m
Houston Hobby
Wed 9/30
11:31 am-10:58 pm
2 stops10h 27m
$733
FlorenceHouston
FLO Florence - HOU Houston Hobby
FLOHOU
Florence
Sun 11/1
5:09 am-1:37 pm
2 stops9h 28m
Houston Hobby
Tue 11/10
6:00 am-3:16 pm
2 stops8h 16m
$809
Sorted by cheapest first
Best time to book a flight from Florence to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Florence with our price prediction graph.
FLO-HO1
FLO-IAH
FLO-HOU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Houston
FLO-HO1
FLO-IAH
FLO-HOU
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated September 11, 2026.
See what other customers who have flown with American Airlines from Florence to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.1
Crew
7.9
Entertainment
6.8
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Food
6.4
Overall
7.1
Crew
7.9
Entertainment
6.8
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from Florence to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Florence
Popular flights
Top destinations
Alternative routes for Florence to Houston
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Houston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Florence to Houston by cabin class
Find flights from Florence to Houston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Florence and Houston flights
Browse other Florence and Houston flight options. Last updated on September 11, 2026.
Other flights from Florence
Browse through other flights departing from Florence. Flights are based on user searches made on Cheapflights and were last updated on September 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Florence to Houston flights
Consider these flights traveling from Florence to Houston.
Top airline flying from Florence to Houston
Discover the top airline that operate flights from Florence to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$318 | FlexibilityNo cancel fee | On-time71% |