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$403+ Cheap flights from Florence, SC (FLO) to Houston

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/14. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — HOU
May 12 — May 191
Tue 5/12
Tue 5/19
1 adult, Economy
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Cheap flight deals from Florence to Houston

Cheapest flights from Florence to Houston
Explore the most affordable flight options available from Florence to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.

This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:05 am
FLO
-
IAH
1 stop5h 21m
American Airlines
Sat 6/205:40 am
IAH
-
FLO
1 stop7h 30m
American Airlines
Deal found 4/9$403
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:16 pm
FLO
-
IAH
1 stop5h 20m
American Airlines
Sat 4/253:22 pm
IAH
-
FLO
1 stop5h 25m
American Airlines
Deal found 4/8$419
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:16 pm
FLO
-
HOU
2 stops8h 31m
American Airlines
Sat 4/2512:42 pm
HOU
-
FLO
2 stops8h 05m
American Airlines
Deal found 4/8$429
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
-
IAH
1 stop6h 59m
American Airlines
Sat 4/183:22 pm
IAH
-
FLO
1 stop5h 25m
American Airlines
Deal found 4/7$479
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
-
HOU
2 stops7h 52m
American Airlines
Sat 4/1812:42 pm
HOU
-
FLO
2 stops8h 05m
American Airlines
Deal found 4/7$489
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:20 am
FLO
-
IAH
1 stop6h 59m
American Airlines
Sat 4/115:00 am
IAH
-
FLO
2 stops9h 50m
American Airlines
Deal found 4/7$589
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:20 am
FLO
-
HOU
2 stops11h 28m
American Airlines
Sat 4/116:01 am
HOU
-
FLO
2 stops8h 49m
American Airlines
Deal found 4/7$595
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:20 am
FLO
-
IAH
1 stop6h 59m
American Airlines
Mon 4/203:22 pm
IAH
-
FLO
1 stop5h 25m
American Airlines
Deal found 4/11$603
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:16 pm
FLO
-
HOU
2 stops8h 31m
American Airlines
Mon 4/2012:42 pm
HOU
-
FLO
2 stops8h 05m
American Airlines
Deal found 4/11$613
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:05 am
FLO
-
HOU
2 stops11h 40m
American Airlines
Sat 6/206:03 am
HOU
-
FLO
2 stops7h 07m
American Airlines
Deal found 4/9$660

Find flight deals from Florence to Houston

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 12, 2026.

Round-trip from

$403
(American Airlines)
From Florence to Houston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Florence to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sun 6/14

5:05 am-9:26 am

1 stop5h 21m

Houston George Bush Intcntl

Sat 6/20

5:40 am-2:10 pm

1 stop7h 30m

$403

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Sun 6/14

5:05 am-3:45 pm

2 stops11h 40m

Houston Hobby

Sat 6/20

6:03 am-2:10 pm

2 stops7h 07m

$660

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/9

Sorted by cheapest first

Best time to book a flight from Florence to Houston

Have a flexible travel schedule? Discover the best time to fly to Houston from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Houston

What is the cheapest month to book a flight from Florence, South Carolina to Houston?

Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $44). Flying from Florence, South Carolina to Houston in March is currently the most expensive (average of $153). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Houston

Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated April 12, 2026.
See what other customers who have flown with American Airlines from Florence to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,569 reviews

Food

6.4

Crew

7.9

Overall

7.1

Entertainment

6.9

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.1
Good
11,569 reviews
American Airlines
7.1
Good
11,569 reviews

Food

6.4

Crew

7.9

Overall

7.1

Entertainment

6.9

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Florence to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Houston?

    For a flight from Florence to Houston, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city. Florence is the only Florence airport and it handles 0 outbound flights to Houston per day. 1 airline has flights to Houston from Florence on a regular basis.

  • How long is the flight from Florence, South Carolina to Houston?

    Airlines like American Airlines fly from Florence, South Carolina to Houston in about 5h 21m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 957 mi.

  • Can I find deals for flights from Florence to Houston that include hotel bookings?

    Yes. In addition to deals on Florence to Houston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Houston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Houston.

  • Can I find deals for business class flights from Florence to Houston?

    Yes. Cheapflights offers flight deals from Florence to Houston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Houston?

    Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $44). Flying from Florence, South Carolina to Houston in March is currently the most expensive (average of $153). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Florence to Houston

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Florence to Houston

Discover the top airline that operate flights from Florence to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$428FlexibilityNo cancel feeOn-time71%

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