$733+ Cheap flights from Houston to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — FLO
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest
Best
Last-minute
Cheapest flights from Houston to FlorenceExplore the most affordable flight options available from Houston to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Houston to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:31 am -
2 stops10h 27m
Sat 9/266:24 am -
2 stops10h 19m
Deal found 9/7![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:31 am -
2 stops10h 27m
Thu 9/246:24 am -
2 stops10h 19m
Deal found 9/9![American Airlines logo]()
$973
Best flights from Houston to FlorenceDiscover carefully curated flight deals from Houston to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Houston to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:31 am -
2 stops10h 27m
Sat 9/266:24 am -
2 stops10h 19m
Deal found 9/7![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:31 am -
2 stops10h 27m
Thu 9/246:24 am -
2 stops10h 19m
Deal found 9/9![American Airlines logo]()
$973
Last-minute flights from Houston to FlorenceDiscover last-minute flight deals from Houston to Florence. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Florence. Data last updated September 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:31 am -
2 stops10h 27m
Sat 9/266:24 am -
2 stops10h 19m
Deal found 9/7![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:31 am -
2 stops10h 27m
Thu 9/246:24 am -
2 stops10h 19m
Deal found 9/9![American Airlines logo]()
$973
Find flight deals from Houston to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Round-trip from | $733 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Houston to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
HoustonFlorence
HOU Houston Hobby - FLO Florence
HOUFLO
Houston Hobby
Tue 9/22
11:31 am-10:58 pm
2 stops10h 27m
Florence
Sat 9/26
6:24 am-3:43 pm
2 stops10h 19m
$733
HoustonFlorence
HOU Houston Hobby - FLO Florence
HOUFLO
Houston Hobby
Wed 9/23
11:31 am-10:58 pm
2 stops10h 27m
Florence
Thu 9/24
6:24 am-3:43 pm
2 stops10h 19m
$973
Sorted by cheapest first
Best time to book a flight from Houston to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Houston with our price prediction graph.
HO1-FLO
HOU-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Florence
HO1-FLO
HOU-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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