$275+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Nov 21 — Nov 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 am -
1 stop8h 29m
Sun 10/256:00 am -
1 stop15h 59m
Deal found 10/21![American Airlines logo]()
$707
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop8h 35m
Mon 11/306:00 am -
1 stop12h 25m
Deal found 10/20![American Airlines logo]()
$807
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/216:00 am -
1 stop17h 35m
Deal found 10/19![American Airlines logo]()
$852
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Sun 12/206:00 am -
2 stops17h 32m
Deal found 10/19![American Airlines logo]()
$856
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:34 pm -
3 stops47h 11m
Tue 11/1710:10 am -
3 stops32h 32m
Deal found 10/20![Multiple Airlines logo]()
$891
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops34h 36m
Mon 12/212:45 pm -
2 stops30h 38m
Deal found 10/19![United Airlines logo]()
$939
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops13h 57m
Sun 12/208:25 am -
2 stops39h 34m
Deal found 10/19![United Airlines logo]()
$949
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:15 pm -
3 stops29h 20m
Sun 11/293:30 am -
2 stops21h 29m
Deal found 10/20![Multiple Airlines logo]()
$1,015
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:46 pm -
2 stops20h 44m
Wed 12/303:30 pm -
2 stops19h 49m
Deal found 10/20![American Airlines logo]()
$1,037
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:01 am -
2 stops17h 15m
Tue 11/176:00 am -
2 stops15h 19m
Deal found 10/20![American Airlines logo]()
$711
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:34 pm -
3 stops47h 11m
Tue 11/1710:10 am -
3 stops32h 32m
Deal found 10/20![Multiple Airlines logo]()
$891
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops34h 36m
Mon 12/212:45 pm -
2 stops30h 38m
Deal found 10/19![United Airlines logo]()
$939
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
2 stops16h 26m
Mon 11/306:00 am -
2 stops16h 59m
Deal found 10/20![American Airlines logo]()
$811
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/216:00 am -
2 stops18h 25m
Deal found 10/19![American Airlines logo]()
$856
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops13h 57m
Sun 12/208:25 am -
2 stops39h 34m
Deal found 10/19![United Airlines logo]()
$949
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:15 am -
2 stops16h 28m
Wed 1/272:44 pm -
2 stops32h 46m
Deal found 10/16![United Airlines logo]()
$1,060
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:46 pm -
2 stops20h 44m
Wed 12/303:30 pm -
2 stops19h 49m
Deal found 10/18![American Airlines logo]()
$1,037
Last-minute flights from St. Louis to GuayaquilDiscover last-minute flight deals from St. Louis to Guayaquil. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated October 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 am -
1 stop8h 29m
Sun 10/256:00 am -
1 stop15h 59m
Deal found 10/21![American Airlines logo]()
$707
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:34 pm -
3 stops47h 11m
Tue 11/1710:10 am -
3 stops32h 32m
Deal found 10/20![Multiple Airlines logo]()
$891
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop8h 35m
Mon 11/306:00 am -
1 stop12h 25m
Deal found 10/20![American Airlines logo]()
$807
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:15 pm -
3 stops29h 20m
Sun 11/293:30 am -
2 stops21h 29m
Deal found 10/20![Multiple Airlines logo]()
$1,015
One-way flights from St. Louis to GuayaquilSearch for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:34 pm -
3 stops28h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:15 pm -
3 stops26h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:09 pm -
2 stops25h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:20 pm -
2 stops27h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$445
This KAYAK deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
2 stops16h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Copa Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:00 am -
1 stop17h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/288:12 pm -
2 stops17h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![American Airlines logo]()
$478
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 22, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $707 (American Airlines) |
One-way from | $275 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Wed 11/11
6:34 pm-11:40 pm
3 stops28h 06m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$275
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Tue 11/24
5:15 pm-8:56 pm
3 stops26h 41m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$317
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Fri 11/27
6:00 am-11:55 pm
2 stops16h 55m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$471
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Tue 11/24
6:15 pm-2:35 pm
1 stop19h 20m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$472
Quickest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Thu 11/26
5:00 am-2:35 pm
1 stop8h 35m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$472
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Wed 11/11
5:00 am-11:16 pm
1 stop17h 16m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$472
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sat 11/28
8:12 pm-2:35 pm
2 stops17h 23m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$478
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Fri 11/27
6:35 pm-5:35 pm
3 stops22h 00m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$484
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Fri 11/27
5:00 am-11:26 pm
1 stop17h 26m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$510
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Wed 11/11
5:01 am-11:16 pm
2 stops17h 15m
Guayaquil Jose Joaquin de Olmedo
Tue 11/17
6:00 am-8:19 pm
2 stops15h 19m
$711
Showing 1-10 of 17 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Guayaquil flight routes
Other flight options
Other flights from St. Louis
Popular flights