HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$390+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:14 am
STL
-
GYE
1 stop16h 27m
American Airlines
Fri 3/132:30 pm
GYE
-
STL
1 stop9h 28m
American Airlines
Deal found 1/20$625
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:20 pm
STL
-
GYE
1 stop19h 10m
American Airlines
Sun 3/152:30 pm
GYE
-
STL
1 stop20h 02m
American Airlines
Deal found 1/22$685
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/810:05 am
STL
-
GYE
2 stops55h 28m
United Airlines
Sun 3/152:35 pm
GYE
-
STL
2 stops42h 46m
United Airlines
Deal found 1/22$744
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/314:42 pm
STL
-
GYE
2 stops30h 00m
United Airlines
Wed 2/48:34 am
GYE
-
STL
2 stops38h 26m
United Airlines
Deal found 1/21$873
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:05 pm
STL
-
GYE
2 stops21h 25m
Multiple Airlines
Thu 3/123:30 am
GYE
-
STL
3 stops35h 59m
Multiple Airlines
Deal found 1/20$1,350

Find flight deals from St. Louis to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$625
(American Airlines)

One-way from

$390
(United Airlines)
Provider with most accurate pricing for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Fly from

St. Louis

Fly to

Guayaquil

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 3/6

5:14 am-10:41 pm

1 stop16h 27m

Guayaquil Jose Joaquin de Olmedo

Fri 3/13

2:30 pm-11:58 pm

1 stop9h 28m

$625

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 3/8

6:20 pm-1:30 pm

1 stop19h 10m

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

2:30 pm-10:32 am

1 stop20h 02m

$685

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 3/8

10:05 am-5:33 pm

2 stops55h 28m

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

2:35 pm-9:21 am

2 stops42h 46m

$744

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 3/6

4:05 pm-2:30 pm

2 stops21h 25m

Guayaquil Jose Joaquin de Olmedo

Thu 3/12

3:30 am-3:29 pm

3 stops35h 59m

$1,350

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 4/26

6:00 am-8:53 pm

2 stops14h 53m

$390

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 4/25

6:00 am-8:53 pm

2 stops14h 53m

$390

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 4/26

11:06 am-1:31 pm

1 stop26h 25m

$398

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 4/25

5:24 am-1:31 pm

1 stop8h 07m

$402

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 4/25

8:13 pm-10:13 am

3 stops38h 00m

$413

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Compare providers for flights from St. Louis to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guayaquil in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated January 22, 2026.
See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,174 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,174 reviews
American Airlines
7.2
Good
11,174 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Guayaquil?

    For as low as $625, American Airlines can have you in Guayaquil from St. Louis in 16h 27m. Airlines will cover a distance of 2902 mi.

  • What is the cheapest airline to fly from St. Louis to Guayaquil round-trip?

    American Airlines, at $516, was found to be the cheapest airline from St. Louis to Guayaquil..

  • Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

    Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.

  • Can I find deals for business class flights from St. Louis to Guayaquil?

    Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Kansas City to Quito flights
St. Louis to Quito flights
Kansas City to Guayaquil flights
Kansas City to Cuenca flights
St. Louis to Baltra flights
St. Louis to San Cristobal flights

Top airline flying from St. Louis to Guayaquil

Discover the top airline that operate flights from St. Louis to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$516Average$996FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights