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Guayaquil

$606+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Aug 30 — Sep 61
Sun 8/30
Sun 9/6
1 adult, Economy
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Cheap flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2026.

This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 am
STL
-
GYE
1 stop17h 45m
American Airlines
Sun 10/256:00 am
GYE
-
STL
1 stop15h 56m
American Airlines
Deal found 7/28$606
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:00 am
STL
-
GYE
1 stop17h 10m
American Airlines
Thu 9/176:00 am
GYE
-
STL
1 stop17h 59m
American Airlines
Deal found 7/26$700
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:20 am
STL
-
GYE
2 stops33h 10m
United Airlines
Wed 9/168:28 am
GYE
-
STL
2 stops38h 02m
United Airlines
Deal found 7/28$970
This Mytrip deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:55 am
STL
-
GYE
3 stops22h 19m
Multiple Airlines
Thu 9/179:10 am
GYE
-
STL
2 stops28h 50m
Multiple Airlines
Deal found 7/26$1,380

Find flight deals from St. Louis to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$606
(American Airlines)
Provider with most accurate pricing for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 10/22

6:00 am-10:45 pm

2 stops16h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

2:29 pm-10:51 am

2 stops20h 22m

$611
Quickest round-trip

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 9/10

5:00 am-10:10 pm

1 stop17h 10m

Guayaquil Jose Joaquin de Olmedo

Thu 9/17

6:00 am-11:59 pm

1 stop17h 59m

$700

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 9/13

7:00 am-11:37 pm

2 stops16h 37m

Guayaquil Jose Joaquin de Olmedo

Wed 9/16

8:28 am-8:47 pm

2 stops36h 19m

$970

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Guayaquil?

    For as low as $611, American Airlines can have you in Guayaquil from St. Louis in 16h 45m. Airlines will cover a distance of 2902 mi.

  • Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

    Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.

  • Can I find deals for business class flights from St. Louis to Guayaquil?

    Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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