HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$374+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$708
(United Airlines)

One-way from

$374
(United Airlines)
From Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo
Search Deals

Find flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:15 amSTL - GYE
2 stops28h 03mUnited Airlines
Fri 2/2012:20 pmGYE - STL
2 stops22h 22mUnited Airlines
Deal found 8/18$708
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:25 amSTL - GYE
1 stop15h 40mAmerican Airlines
Fri 2/207:35 amGYE - STL
2 stops25h 31mAmerican Airlines
Deal found 8/18$787

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Fly from

St. Louis

Fly to

Guayaquil

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

6:15 am-11:18 am

2 stops28h 03m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

12:20 pm-9:42 am

2 stops22h 22m

$708

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

5:25 am-10:05 pm

1 stop15h 40m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

7:35 am-8:06 am

2 stops25h 31m

$787

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 11/19

8:20 am-1:34 pm

2 stops28h 14m

$374

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 11/19

1:00 pm-9:15 am

3 stops43h 15m

$379

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 1/9

6:15 am-10:20 am

2 stops27h 05m

$403

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 11/19

5:21 am-10:40 pm

1 stop16h 19m

$452

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 1/9

5:02 pm-10:05 pm

1 stop28h 03m

$453

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 11/7

1:30 pm-10:23 pm

2 stops31h 53m

$515

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 11/7

8:20 am-1:34 pm

2 stops28h 14m

$564

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 11/7

5:21 am-10:40 pm

1 stop16h 19m

$581

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 20, 2025.
See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Comfort

7.2

Boarding

7.5

Crew

8.0

Entertainment

6.9

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Comfort

7.2

Boarding

7.5

Crew

8.0

Entertainment

6.9

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Guayaquil?

    For as low as $787, United Airlines can have you in Guayaquil from St. Louis in 15h 40m. Airlines will cover a distance of 2902 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from St. Louis to Guayaquil round-trip?

    American Airlines, at $516, was found to be the cheapest airline from St. Louis to Guayaquil..

  • Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

    Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.

  • Can I find deals for business class flights from St. Louis to Guayaquil?

    Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Guayaquil (average of $440). Flying from St. Louis to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Quito flights
Kansas City to Quito flights
Kansas City to Guayaquil flights
Kansas City to Cuenca flights
St. Louis to Baltra flights
St. Louis to San Cristobal flights

Top airline flying from St. Louis to Guayaquil

Discover the top airline that operate flights from St. Louis to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$516Average$996FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.