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Guayaquil

$379+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Spirit Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:47 pmSTL - GYE
1 stop7h 56mSpirit Airlines
Wed 12/1012:49 amGYE - STL
1 stop14h 03mSpirit Airlines
Deal found 11/19$458
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:12 pmSTL - GYE
2 stops31h 28mDelta
Thu 12/118:40 pmGYE - STL
2 stops20h 26mDelta
Deal found 11/19$838
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:15 amSTL - GYE
2 stops37h 28mUnited Airlines
Fri 2/202:35 pmGYE - STL
2 stops43h 48mUnited Airlines
Deal found 11/19$1,003
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:45 pmSTL - GYE
2 stops28h 56mUnited Airlines
Tue 1/2012:20 pmGYE - STL
2 stops22h 02mUnited Airlines
Deal found 11/20$1,216
This Avianca deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:30 amSTL - GYE
2 stops14h 05mAvianca
Thu 2/193:30 amGYE - STL
2 stops17h 53mAvianca
Deal found 11/19$1,314
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:10 amSTL - GYE
1 stop16h 56mAmerican Airlines
Fri 2/207:11 amGYE - STL
1 stop15h 54mAmerican Airlines
Deal found 11/19$1,342
This oojo deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:55 amSTL - GYE
2 stops30h 50mAvianca
Mon 1/193:30 amGYE - STL
2 stops31h 43mAvianca
Deal found 11/20$1,989
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:55 pmSTL - GYE
1 stop13h 25mDelta
Tue 1/204:30 pmGYE - STL
2 stops20h 24mDelta
Deal found 11/20$2,857

Cheap flight deals from St. Louis to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$372
(Spirit Airlines)
Provider with most accurate pricing for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Fly from

St. Louis

Fly to

Guayaquil

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 12/7

2:47 pm-11:43 pm

1 stop7h 56m

Guayaquil Jose Joaquin de Olmedo

Wed 12/10

12:49 am-1:52 pm

1 stop14h 03m

$458

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 12/7

5:12 pm-1:40 am

2 stops31h 28m

Guayaquil Jose Joaquin de Olmedo

Thu 12/11

8:40 pm-4:06 pm

2 stops20h 26m

$838

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

6:15 am-8:43 pm

2 stops37h 28m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

2:35 pm-9:23 am

2 stops43h 48m

$1,003

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 1/3

6:35 pm-11:42 pm

2 stops28h 07m

Guayaquil Jose Joaquin de Olmedo

Sat 1/10

8:34 am-9:22 am

2 stops25h 48m

$1,271

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

8:30 am-11:35 pm

2 stops14h 05m

Guayaquil Jose Joaquin de Olmedo

Thu 2/19

3:30 am-8:23 pm

2 stops17h 53m

$1,314

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

5:10 am-11:06 pm

1 stop16h 56m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

7:11 am-10:05 pm

1 stop15h 54m

$1,342

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 1/3

6:00 pm-11:50 pm

1 stop28h 50m

Guayaquil Jose Joaquin de Olmedo

Sat 1/10

7:15 am-10:44 pm

2 stops16h 29m

$1,769

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 4/26

2:18 pm-7:20 am

2 stops17h 02m

$379

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 4/25

6:00 am-11:42 pm

2 stops17h 42m

$380

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 4/25

11:51 am-7:20 am

2 stops19h 29m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 14 results
1
2

Compare providers for flights from St. Louis to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guayaquil in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated November 20, 2025.
See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,047 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.
American Airlines
7.2
Good
11,047 reviews
American Airlines
7.2
Good
11,047 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Guayaquil?

    For as low as $458, Spirit Airlines can have you in Guayaquil from St. Louis in 7h 56m. Airlines will cover a distance of 2902 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from St. Louis to Guayaquil round-trip?

    American Airlines, at $516, was found to be the cheapest airline from St. Louis to Guayaquil..

  • Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

    Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.

  • Can I find deals for business class flights from St. Louis to Guayaquil?

    Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for St. Louis to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from St. Louis to Guayaquil

Discover the top airline that operate flights from St. Louis to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$516Average$996FlexibilityNo cancel feeOn-time71%

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