$755+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Jul 5 — Jul 121
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
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Best
Last-minute
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:29 pm
STL
- GYE
1 stop18h 56m
American Airlines
Mon 7/276:00 am
GYE
- STL
1 stop16h 54m
American Airlines
Deal found 6/5![American Airlines logo]()
$755
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
STL
- GYE
2 stops17h 23m
Copa Airlines
Fri 8/2112:22 pm
GYE
- STL
2 stops32h 05m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$770
This Trip.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:57 pm
STL
- GYE
3 stops30h 33m
Multiple Airlines
Sat 8/86:50 pm
GYE
- STL
3 stops22h 47m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$802
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:33 am
STL
- GYE
1 stop8h 00m
American Airlines
Sun 10/258:25 am
GYE
- STL
1 stop14h 50m
American Airlines
Deal found 6/4![American Airlines logo]()
$808
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:15 am
STL
- GYE
2 stops12h 23m
Copa Airlines
Wed 8/198:28 am
GYE
- STL
2 stops25h 42m
Copa Airlines
Deal found 6/2![Copa Airlines logo]()
$811
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:35 am
STL
- GYE
1 stop10h 04m
American Airlines
Fri 8/216:00 am
GYE
- STL
1 stop16h 40m
American Airlines
Deal found 6/4![American Airlines logo]()
$835
This KAYAK deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:14 am
STL
- GYE
2 stops11h 17m
Copa Airlines
Sat 8/86:00 am
GYE
- STL
2 stops16h 45m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$920
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:00 am
STL
- GYE
1 stop16h 39m
American Airlines
Wed 8/196:00 am
GYE
- STL
1 stop16h 40m
American Airlines
Deal found 6/2![American Airlines logo]()
$956
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:29 pm
STL
- GYE
1 stop18h 56m
American Airlines
Mon 7/276:00 am
GYE
- STL
1 stop16h 54m
American Airlines
Deal found 6/5![American Airlines logo]()
$755
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
STL
- GYE
2 stops17h 23m
Copa Airlines
Fri 8/2112:22 pm
GYE
- STL
2 stops32h 05m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$770
This Trip.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:57 pm
STL
- GYE
3 stops30h 33m
Multiple Airlines
Sat 8/86:50 pm
GYE
- STL
3 stops22h 47m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$802
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:15 am
STL
- GYE
2 stops12h 23m
Copa Airlines
Wed 8/198:28 am
GYE
- STL
2 stops25h 42m
Copa Airlines
Deal found 6/2![Copa Airlines logo]()
$811
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:35 am
STL
- GYE
1 stop10h 04m
American Airlines
Fri 8/216:00 am
GYE
- STL
1 stop16h 40m
American Airlines
Deal found 6/4![American Airlines logo]()
$835
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:00 am
STL
- GYE
1 stop16h 39m
American Airlines
Wed 8/196:00 am
GYE
- STL
1 stop16h 40m
American Airlines
Deal found 6/2![American Airlines logo]()
$956
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:18 am
STL
- GYE
1 stop17h 19m
American Airlines
Sat 8/86:00 am
GYE
- STL
2 stops17h 34m
American Airlines
Deal found 6/5![American Airlines logo]()
$969
This Mytrip deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:10 pm
STL
- GYE
2 stops26h 25m
Multiple Airlines
Wed 8/193:45 pm
GYE
- STL
3 stops28h 22m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$1,340
This Mytrip deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:10 pm
STL
- GYE
2 stops29h 25m
Multiple Airlines
Fri 8/2110:05 am
GYE
- STL
3 stops34h 17m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$1,579
Last-minute flights from St. Louis to GuayaquilDiscover last-minute flight deals from St. Louis to Guayaquil. Data last updated June 5, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated June 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:29 pm
STL
- GYE
1 stop18h 56m
American Airlines
Mon 7/276:00 am
GYE
- STL
1 stop16h 54m
American Airlines
Deal found 6/5![American Airlines logo]()
$755
This Mytrip deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:10 pm
STL
- GYE
2 stops20h 45m
Multiple Airlines
Sun 7/263:30 am
GYE
- STL
3 stops34h 32m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$2,079
This Trip.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:57 pm
STL
- GYE
3 stops30h 33m
Multiple Airlines
Sat 8/86:50 pm
GYE
- STL
3 stops22h 47m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$802
This KAYAK deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:14 am
STL
- GYE
2 stops11h 17m
Copa Airlines
Sat 8/86:00 am
GYE
- STL
2 stops16h 45m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$920
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:18 am
STL
- GYE
1 stop17h 19m
American Airlines
Sat 8/86:00 am
GYE
- STL
2 stops17h 34m
American Airlines
Deal found 6/5![American Airlines logo]()
$969
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $755 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sat 7/18
6:29 pm-1:25 pm
1 stop18h 56m
Guayaquil Jose Joaquin de Olmedo
Mon 7/27
6:00 am-10:54 pm
1 stop16h 54m
$755
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 8/14
6:15 am-11:38 pm
2 stops17h 23m
Guayaquil Jose Joaquin de Olmedo
Fri 8/21
12:22 pm-8:27 pm
2 stops32h 05m
$770
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Wed 7/29
4:57 pm-11:30 pm
3 stops30h 33m
Guayaquil Jose Joaquin de Olmedo
Sat 8/8
6:50 pm-5:37 pm
3 stops22h 47m
$802
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Thu 8/13
11:15 am-11:38 pm
2 stops12h 23m
Guayaquil Jose Joaquin de Olmedo
Wed 8/19
8:28 am-10:10 am
2 stops25h 42m
$811
Quickest round-trip
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 8/14
11:35 am-9:39 pm
1 stop10h 04m
Guayaquil Jose Joaquin de Olmedo
Fri 8/21
6:00 am-10:40 pm
1 stop16h 40m
$835
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Thu 8/13
5:00 am-9:39 pm
1 stop16h 39m
Guayaquil Jose Joaquin de Olmedo
Wed 8/19
6:00 am-10:40 pm
1 stop16h 40m
$956
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Wed 7/29
5:18 am-10:37 pm
1 stop17h 19m
Guayaquil Jose Joaquin de Olmedo
Sat 8/8
6:00 am-11:34 pm
2 stops17h 34m
$969
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Thu 8/13
12:10 pm-2:35 pm
2 stops26h 25m
Guayaquil Jose Joaquin de Olmedo
Wed 8/19
3:45 pm-8:07 pm
3 stops28h 22m
$1,340
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 8/14
12:10 pm-5:35 pm
2 stops29h 25m
Guayaquil Jose Joaquin de Olmedo
Fri 8/21
10:05 am-8:22 pm
3 stops34h 17m
$1,579
Sorted by cheapest first
Compare providers for flights from St. Louis to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guayaquil in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated June 5, 2026.
See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Crew
7.9
Food
6.4
Overall
7.1
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Entertainment
6.9
Crew
7.9
Food
6.4
Overall
7.1
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from St. Louis to Guayaquil, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 5, 2026.
St. Louis and Guayaquil flights
Browse other St. Louis and Guayaquil flight options. Last updated on June 5, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on June 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from St. Louis to Guayaquil
Discover the top airline that operate flights from St. Louis to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$516 | Average$996 | FlexibilityNo cancel fee | On-time71% |