$401+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Jun 21 — Jun 281
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:10 am
STL
- GYE
1 stop8h 17m
American Airlines
Mon 2/87:15 am
GYE
- STL
1 stop11h 09m
American Airlines
Deal found 5/19![American Airlines logo]()
$695
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:18 am
STL
- GYE
1 stop17h 19m
American Airlines
Tue 7/286:00 am
GYE
- STL
2 stops17h 32m
American Airlines
Deal found 5/20![American Airlines logo]()
$700
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:08 pm
STL
- GYE
1 stop19h 25m
American Airlines
Sat 11/76:00 am
GYE
- STL
1 stop17h 32m
American Airlines
Deal found 5/19![American Airlines logo]()
$747
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:21 am
STL
- GYE
1 stop8h 06m
American Airlines
Sat 11/146:00 am
GYE
- STL
1 stop17h 32m
American Airlines
Deal found 5/19![American Airlines logo]()
$778
This KAYAK deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:05 pm
STL
- GYE
2 stops25h 46m
Copa Airlines
Mon 6/86:27 pm
GYE
- STL
2 stops27h 03m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$780
This Ovago deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:13 pm
STL
- GYE
2 stops22h 07m
Copa Airlines
Mon 6/226:27 pm
GYE
- STL
2 stops27h 03m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$781
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:46 pm
STL
- GYE
2 stops19h 47m
American Airlines
Sun 10/258:25 am
GYE
- STL
1 stop14h 50m
American Airlines
Deal found 5/22![American Airlines logo]()
$823
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:16 am
STL
- GYE
1 stop17h 20m
American Airlines
Mon 6/82:31 pm
GYE
- STL
2 stops18h 01m
American Airlines
Deal found 5/21![American Airlines logo]()
$1,019
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:16 am
STL
- GYE
1 stop17h 20m
American Airlines
Mon 6/222:31 pm
GYE
- STL
2 stops18h 01m
American Airlines
Deal found 5/19![American Airlines logo]()
$1,029
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:18 am
STL
- GYE
1 stop17h 19m
American Airlines
Tue 7/286:00 am
GYE
- STL
2 stops17h 32m
American Airlines
Deal found 5/20![American Airlines logo]()
$700
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:28 pm
STL
- GYE
2 stops19h 59m
American Airlines
Sat 11/73:30 pm
GYE
- STL
2 stops18h 28m
American Airlines
Deal found 5/19![American Airlines logo]()
$752
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:46 pm
STL
- GYE
2 stops19h 47m
American Airlines
Sun 10/252:30 pm
GYE
- STL
2 stops21h 30m
American Airlines
Deal found 5/18![American Airlines logo]()
$823
Last-minute flights from St. Louis to GuayaquilDiscover last-minute flight deals from St. Louis to Guayaquil. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated May 22, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:05 pm
STL
- GYE
2 stops25h 46m
Copa Airlines
Mon 6/86:27 pm
GYE
- STL
2 stops27h 03m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$780
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:16 am
STL
- GYE
1 stop17h 20m
American Airlines
Mon 6/82:31 pm
GYE
- STL
2 stops18h 01m
American Airlines
Deal found 5/21![American Airlines logo]()
$1,019
This Mytrip deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:40 am
STL
- GYE
3 stops32h 55m
Multiple Airlines
Mon 6/81:40 pm
GYE
- STL
3 stops22h 26m
Multiple Airlines
Deal found 5/21![Multiple Airlines logo]()
$1,313
This Ovago deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:13 pm
STL
- GYE
2 stops22h 07m
Copa Airlines
Mon 6/226:27 pm
GYE
- STL
2 stops27h 03m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$781
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:16 am
STL
- GYE
1 stop17h 20m
American Airlines
Mon 6/222:31 pm
GYE
- STL
2 stops18h 01m
American Airlines
Deal found 5/19![American Airlines logo]()
$1,029
This Mytrip deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:05 pm
STL
- GYE
3 stops34h 25m
Multiple Airlines
Sun 6/213:30 am
GYE
- STL
2 stops32h 51m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$1,450
One-way flights from St. Louis to GuayaquilSearch for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:31 pm
STL
- GYE
2 stops29h 05m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:06 pm
STL
- GYE
3 stops24h 29m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$406
This KAYAK deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:10 am
STL
- GYE
2 stops30h 19m
Copa Airlines
Deal found 5/22![Copa Airlines logo]()
$453
This KAYAK deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:35 am
STL
- GYE
2 stops12h 16m
Copa Airlines
Deal found 5/22![Copa Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:08 pm
STL
- GYE
3 stops27h 53m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$532
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:25 pm
STL
- GYE
1 stop14h 49m
Delta
Deal found 5/22![Delta logo]()
$582
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:16 am
STL
- GYE
1 stop17h 20m
American Airlines
Deal found 5/22![American Airlines logo]()
$711
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:16 am
STL
- GYE
1 stop8h 15m
American Airlines
Deal found 5/22![American Airlines logo]()
$771
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $700 (American Airlines) |
One-way from | $401 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Tue 7/21
5:18 am-10:37 pm
1 stop17h 19m
Guayaquil Jose Joaquin de Olmedo
Tue 7/28
6:00 am-11:32 pm
2 stops17h 32m
$700
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sat 10/31
6:28 pm-2:27 pm
2 stops19h 59m
Guayaquil Jose Joaquin de Olmedo
Sat 11/7
3:30 pm-8:58 am
2 stops18h 28m
$752
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Thu 10/22
5:46 pm-1:33 pm
2 stops19h 47m
Guayaquil Jose Joaquin de Olmedo
Sun 10/25
2:30 pm-12:00 pm
2 stops21h 30m
$823
Cheapest one-way
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sun 6/28
6:31 pm-11:36 pm
2 stops29h 05m
$401
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 6/26
5:06 pm-5:35 pm
3 stops24h 29m
$406
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 5/29
11:10 am-5:29 pm
2 stops30h 19m
$453
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 5/29
4:25 pm-7:14 am
1 stop14h 49m
$582
Quickest one-way
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 6/26
5:16 am-1:31 pm
1 stop8h 15m
$771
Sorted by cheapest first
Compare providers for flights from St. Louis to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guayaquil in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated May 22, 2026.
See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Crew
7.9
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Overall
7.1
Crew
7.9
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
St. Louis and Guayaquil flights
Browse other St. Louis and Guayaquil flight options. Last updated on May 22, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from St. Louis to Guayaquil
Discover the top airline that operate flights from St. Louis to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$516 | Average$996 | FlexibilityNo cancel fee | On-time71% |