$270+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
May 20 — May 271
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
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Best
Last-minute
One-way
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 20, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 20, 2026.
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:33 am
STL
- GYE
1 stop8h 00m
American Airlines
Sun 10/258:25 am
GYE
- STL
1 stop8h 58m
American Airlines
Deal found 4/17![American Airlines logo]()
$798
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:35 am
STL
- GYE
2 stops15h 02m
United Airlines
Sun 10/258:34 am
GYE
- STL
2 stops13h 32m
United Airlines
Deal found 4/17![United Airlines logo]()
$823
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
STL
- GYE
2 stops15h 12m
American Airlines
Fri 7/316:00 am
GYE
- STL
2 stops14h 55m
American Airlines
Deal found 4/19![American Airlines logo]()
$1,009
This Ovago deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:24 am
STL
- GYE
1 stop15h 48m
GOL
Fri 7/312:37 pm
GYE
- STL
2 stops20h 11m
GOL
Deal found 4/19![GOL logo]()
$1,085
This Avianca deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:45 am
STL
- GYE
2 stops24h 10m
Avianca
Sun 5/36:50 pm
GYE
- STL
2 stops39h 38m
Avianca
Deal found 4/15![Avianca logo]()
$1,225
This Mytrip deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:20 pm
STL
- GYE
3 stops27h 44m
Multiple Airlines
Thu 7/303:30 am
GYE
- STL
2 stops16h 37m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$1,470
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 20, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 20, 2026.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 am
STL
- GYE
2 stops15h 52m
American Airlines
Fri 7/316:00 am
GYE
- STL
2 stops17h 32m
American Airlines
Deal found 4/19![American Airlines logo]()
$1,009
This Avianca deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:45 am
STL
- GYE
2 stops24h 10m
Avianca
Sun 5/36:50 pm
GYE
- STL
2 stops39h 38m
Avianca
Deal found 4/15![Avianca logo]()
$1,225
This Mytrip deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:20 pm
STL
- GYE
3 stops27h 44m
Multiple Airlines
Thu 7/303:30 am
GYE
- STL
2 stops34h 32m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$1,470
Last-minute flights from St. Louis to GuayaquilDiscover last-minute flight deals from St. Louis to Guayaquil. Data last updated April 20, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated April 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
STL
- GYE
2 stops15h 12m
American Airlines
Fri 7/316:00 am
GYE
- STL
2 stops14h 55m
American Airlines
Deal found 4/19![American Airlines logo]()
$1,009
This Ovago deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:24 am
STL
- GYE
1 stop15h 48m
GOL
Fri 7/312:37 pm
GYE
- STL
2 stops20h 11m
GOL
Deal found 4/19![GOL logo]()
$1,085
This Mytrip deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:20 pm
STL
- GYE
3 stops27h 44m
Multiple Airlines
Thu 7/303:30 am
GYE
- STL
2 stops16h 37m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$1,470
This Avianca deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:45 am
STL
- GYE
2 stops24h 10m
Avianca
Sun 5/36:50 pm
GYE
- STL
2 stops39h 38m
Avianca
Deal found 4/15![Avianca logo]()
$1,225
One-way flights from St. Louis to GuayaquilSearch for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated April 20, 2026.
Search for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated April 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:06 pm
STL
- GYE
3 stops48h 23m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
STL
- GYE
2 stops16h 37m
American Airlines
Deal found 4/19![American Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2610:09 am
STL
- GYE
2 stops37h 29m
United Airlines
Deal found 4/16![United Airlines logo]()
$500
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:42 am
STL
- GYE
2 stops19h 13m
Delta
Deal found 4/17![Delta logo]()
$562
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:24 am
STL
- GYE
1 stop15h 48m
American Airlines
Deal found 4/16![American Airlines logo]()
$582
This FlightHub deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:35 am
STL
- GYE
3 stops35h 45m
Avianca
Deal found 4/19![Avianca logo]()
$732
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $770 (American Airlines) |
One-way from | $442 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 20, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 5/1
5:20 am-9:12 pm
2 stops15h 52m
Guayaquil Jose Joaquin de Olmedo
Fri 7/31
6:00 am-11:32 pm
2 stops17h 32m
$1,009
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sat 5/2
8:45 am-8:55 am
2 stops24h 10m
Guayaquil Jose Joaquin de Olmedo
Sun 5/3
6:50 pm-10:28 am
2 stops39h 38m
$1,225
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Fri 5/1
7:20 pm-11:04 pm
3 stops27h 44m
Guayaquil Jose Joaquin de Olmedo
Thu 7/30
3:30 am-2:02 pm
2 stops34h 32m
$1,470
Cheapest one-way
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Mon 6/15
4:17 pm-5:29 pm
2 stops25h 12m
$419
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Mon 6/15
6:00 am-10:37 pm
2 stops16h 37m
$442
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sun 4/26
10:09 am-11:38 pm
2 stops37h 29m
$500
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sun 4/26
11:42 am-6:55 am
2 stops19h 13m
$562
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sat 4/25
5:24 am-9:12 pm
1 stop15h 48m
$582
Quickest one-way
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sun 4/26
5:24 am-1:31 pm
1 stop8h 07m
$582
Sorted by cheapest first
Compare providers for flights from St. Louis to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guayaquil in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 20, 2026.
See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Overall
7.1
Crew
7.9
Comfort
7.2
Entertainment
6.9
Food
6.4
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Boarding
7.5
Overall
7.1
Crew
7.9
Comfort
7.2
Entertainment
6.9
Food
6.4
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 20, 2026.
St. Louis and Guayaquil flights
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from St. Louis to Guayaquil
Discover the top airline that operate flights from St. Louis to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$516 | Average$996 | FlexibilityNo cancel fee | On-time71% |