$727+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Dec 14 — Dec 211
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
Cheapest
Best
Last-minute
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop17h 52m
Tue 12/86:00 am -
1 stop10h 44m
Deal found 11/9![American Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/213:30 pm -
2 stops17h 59m
Deal found 11/10![American Airlines logo]()
$825
This BusinessClass deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:00 pm -
2 stops23h 31m
Mon 12/213:30 pm -
2 stops18h 57m
Deal found 11/12![GOL logo]()
$842
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/255:00 am -
1 stop17h 37m
Wed 2/36:03 am -
1 stop12h 23m
Deal found 11/10![American Airlines logo]()
$727
This KAYAK deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:15 am -
2 stops13h 42m
Tue 1/1212:22 pm -
2 stops22h 09m
Deal found 11/9![Copa Airlines logo]()
$1,045
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/161:17 pm -
3 stops33h 26m
Thu 1/2112:22 pm -
2 stops29h 21m
Deal found 11/10![United Airlines logo]()
$1,055
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:50 am -
2 stops17h 02m
Tue 12/86:00 am -
2 stops13h 33m
Deal found 11/9![American Airlines logo]()
$731
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/226:48 am -
2 stops15h 49m
Mon 2/16:03 am -
1 stop17h 39m
Deal found 11/12![American Airlines logo]()
$741
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1612:21 pm -
1 stop10h 38m
Tue 2/237:00 am -
2 stops17h 54m
Deal found 11/9![American Airlines logo]()
$758
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:15 am -
2 stops16h 28m
Thu 1/288:25 am -
2 stops15h 05m
Deal found 11/13![United Airlines logo]()
$1,080
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/213:30 pm -
2 stops17h 59m
Deal found 11/10![American Airlines logo]()
$825
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/105:00 am -
1 stop17h 59m
Sat 3/203:06 pm -
1 stop20h 25m
Deal found 11/12![American Airlines logo]()
$913
Last-minute flights from St. Louis to GuayaquilDiscover last-minute flight deals from St. Louis to Guayaquil. Data last updated November 14, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated November 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop17h 52m
Tue 12/86:00 am -
1 stop10h 44m
Deal found 11/9![American Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/213:30 pm -
2 stops17h 59m
Deal found 11/10![American Airlines logo]()
$825
This BusinessClass deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:00 pm -
2 stops23h 31m
Mon 12/213:30 pm -
2 stops18h 57m
Deal found 11/12![GOL logo]()
$842
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 14, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $707 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Mon 1/25
5:00 am-11:37 pm
1 stop17h 37m
Guayaquil Jose Joaquin de Olmedo
Wed 2/3
6:03 am-5:26 pm
1 stop12h 23m
$727
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Wed 12/2
5:50 am-11:52 pm
2 stops17h 02m
Guayaquil Jose Joaquin de Olmedo
Tue 12/8
6:00 am-6:33 pm
2 stops13h 33m
$731
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Fri 1/22
6:48 am-11:37 pm
2 stops15h 49m
Guayaquil Jose Joaquin de Olmedo
Mon 2/1
6:03 am-10:42 pm
1 stop17h 39m
$741
Quickest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Tue 2/16
12:21 pm-11:59 pm
1 stop10h 38m
Guayaquil Jose Joaquin de Olmedo
Tue 2/23
7:00 am-11:54 pm
2 stops17h 54m
$758
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sat 12/12
6:15 pm-2:31 pm
1 stop19h 16m
Guayaquil Jose Joaquin de Olmedo
Mon 12/21
3:30 pm-8:29 am
2 stops17h 59m
$825
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Wed 3/10
5:00 am-11:59 pm
1 stop17h 59m
Guayaquil Jose Joaquin de Olmedo
Sat 3/20
3:06 pm-11:31 am
1 stop20h 25m
$913
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 12/27
6:15 am-8:57 pm
2 stops13h 42m
Guayaquil Jose Joaquin de Olmedo
Tue 1/12
12:22 pm-9:31 am
2 stops22h 09m
$1,045
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sat 1/16
1:17 pm-11:43 pm
3 stops33h 26m
Guayaquil Jose Joaquin de Olmedo
Thu 1/21
12:22 pm-4:43 pm
2 stops29h 21m
$1,055
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Mon 1/25
6:15 am-11:43 pm
2 stops16h 28m
Guayaquil Jose Joaquin de Olmedo
Thu 1/28
8:25 am-10:30 pm
2 stops15h 05m
$1,080
Sorted by cheapest first
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
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