$432+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Sep 23 — Sep 301
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
Cheapest
Best
One-way
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:00 am -
1 stop17h 39m
Tue 10/136:00 am -
1 stop15h 59m
Deal found 8/22![American Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:48 am -
2 stops11h 51m
Sun 10/252:29 pm -
2 stops20h 22m
Deal found 8/21![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:07 pm -
1 stop19h 22m
Sat 10/246:00 am -
1 stop15h 59m
Deal found 8/21![American Airlines logo]()
$663
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:36 pm -
2 stops20h 54m
Wed 12/303:30 pm -
2 stops19h 49m
Deal found 8/22![American Airlines logo]()
$689
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:00 am -
1 stop17h 39m
Tue 10/136:00 am -
1 stop15h 59m
Deal found 8/22![American Airlines logo]()
$626
This KAYAK deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:30 am -
2 stops15h 25m
Fri 11/274:22 am -
2 stops13h 30m
Deal found 8/21![Copa Airlines logo]()
$760
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 am -
1 stop17h 39m
Sun 10/256:00 am -
1 stop15h 59m
Deal found 8/21![American Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:00 am -
2 stops17h 39m
Sat 10/246:00 am -
2 stops17h 42m
Deal found 8/21![American Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:36 pm -
2 stops20h 54m
Wed 12/303:30 pm -
2 stops19h 49m
Deal found 8/22![American Airlines logo]()
$689
One-way flights from St. Louis to GuayaquilSearch for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
Search for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/143:40 pm -
2 stops15h 22m
Deal found 8/24![Delta logo]()
$432
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:16 pm -
1 stop19h 15m
Deal found 8/24![American Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/141:08 pm -
3 stops51h 29m
Deal found 8/24![United Airlines logo]()
$532
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 24, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $626 (American Airlines) |
One-way from | $432 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Tue 10/6
5:00 am-10:39 pm
1 stop17h 39m
Guayaquil Jose Joaquin de Olmedo
Tue 10/13
6:00 am-9:59 pm
1 stop15h 59m
$626
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Thu 10/22
5:00 am-10:39 pm
1 stop17h 39m
Guayaquil Jose Joaquin de Olmedo
Sun 10/25
6:00 am-9:59 pm
1 stop15h 59m
$626
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sat 10/10
5:00 am-10:39 pm
2 stops17h 39m
Guayaquil Jose Joaquin de Olmedo
Sat 10/24
6:00 am-11:42 pm
2 stops17h 42m
$681
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 12/20
4:36 pm-2:30 pm
2 stops20h 54m
Guayaquil Jose Joaquin de Olmedo
Wed 12/30
3:30 pm-10:19 am
2 stops19h 49m
$689
Quickest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Mon 11/23
7:30 am-11:55 pm
2 stops15h 25m
Guayaquil Jose Joaquin de Olmedo
Fri 11/27
4:22 am-4:52 pm
2 stops13h 30m
$760
Cheapest one-way
Quickest one-way
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 2/14
3:40 pm-8:02 am
2 stops15h 22m
$432
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 2/14
6:16 pm-2:31 pm
1 stop19h 15m
$439
Sorted by cheapest first
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
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