How long is the flight from St. Louis to Guayaquil?

For as low as $577, Spirit Airlines can have you in Guayaquil from St. Louis in 10h 25m. Airlines will cover a distance of 2902 mi. This flight may include one or multiple stops.

What is the cheapest airline to fly from St. Louis to Guayaquil round-trip?

American Airlines, at $516, was found to be the cheapest airline from St. Louis to Guayaquil..

What is the cheapest month to book a flight from St. Louis to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Guayaquil (average of $440). Flying from St. Louis to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from St. Louis to Guayaquil?

Travelers seeking maximum savings on their St. Louis to Guayaquil flight should consider departing on Wednesday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

What is the cheapest time of day to fly from STL to GYE?

Unlike in the morning, when flights are generally more expensive, you can save up to 7% on flights from St. Louis to Guayaquil by exploring options for tickets at noon.

Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Guayaquil?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.

Can I find deals for business class flights from St. Louis to Guayaquil?

Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$160+ Flights from St. Louis to Guayaquil

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Cheap flight deals from St. Louis to Guayaquil

Round-trip from	$577 (KAYAK)
One-way from	$160 (Kiwi.com)

From Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo

Search Deals

One-way flight from Lambert-St Louis to Guayaquil Jose Joaquin de Olmedo

Search Deals

Find flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Thu 12/46:15 amSTL - GYE

2 stops28h 03mUnited Airlines

Fri 2/202:35 pmGYE - STL

2 stops21h 11mUnited Airlines

Deal found 9/15

$597

Mon 9/296:15 amSTL - GYE

2 stops31h 31mUnited Airlines

Thu 10/22:54 pmGYE - STL

2 stops31h 06mUnited Airlines

Deal found 9/15

$841

Thu 12/45:10 amSTL - GYE

1 stop16h 56mAmerican Airlines

Fri 2/202:33 pmGYE - STL

1 stop10h 13mAmerican Airlines

Deal found 9/15

$902

Mon 9/295:28 amSTL - GYE

1 stop14h 20mAmerican Airlines

Thu 10/28:20 amGYE - STL

1 stop15h 39mAmerican Airlines

Deal found 9/15

$952

Mon 9/291:30 pmSTL - GYE

3 stops33h 10mMultiple Airlines

Wed 10/13:15 amGYE - STL

3 stops32h 14mMultiple Airlines

Deal found 9/15

$1,119

Best flights from St. Louis to Guayaquil
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2025.

Thu 2/1912:20 pmSTL - GYE

1 stop10h 25mSpirit Airlines

Sat 2/2812:59 amGYE - STL

1 stop11h 02mSpirit Airlines

Deal found 9/16

$577

Thu 12/46:15 amSTL - GYE

2 stops28h 03mUnited Airlines

Fri 2/202:35 pmGYE - STL

2 stops21h 11mUnited Airlines

Deal found 9/15

$597

Thu 2/195:11 pmSTL - GYE

2 stops53h 34mMultiple Airlines

Sat 2/2812:59 amGYE - STL

1 stop11h 02mMultiple Airlines

Deal found 9/16

$643

Thu 2/195:19 amSTL - GYE

1 stop7h 14mAmerican Airlines

Sun 3/12:33 pmGYE - STL

1 stop10h 13mAmerican Airlines

Deal found 9/16

$753

Thu 2/194:17 pmSTL - GYE

2 stops42h 01mUnited Airlines

Sun 3/112:20 pmGYE - STL

2 stops34h 54mUnited Airlines

Deal found 9/16

$615

Thu 12/45:10 amSTL - GYE

1 stop16h 56mAmerican Airlines

Fri 2/202:33 pmGYE - STL

1 stop10h 13mAmerican Airlines

Deal found 9/15

$902

Mon 9/296:15 amSTL - GYE

2 stops29h 00mUnited Airlines

Wed 10/13:15 amGYE - STL

2 stops18h 45mUnited Airlines

Deal found 9/15

$851

Mon 9/295:28 amSTL - GYE

1 stop14h 20mAmerican Airlines

Thu 10/28:20 amGYE - STL

1 stop15h 39mAmerican Airlines

Deal found 9/15

$952

Last-minute flights from St. Louis to Guayaquil
Discover last-minute flight deals from St. Louis to Guayaquil. Data last updated September 17, 2025 and is based on user searches.

Mon 9/296:15 amSTL - GYE

2 stops31h 31mUnited Airlines

Thu 10/22:54 pmGYE - STL

2 stops31h 06mUnited Airlines

Deal found 9/15

$841

Mon 9/295:28 amSTL - GYE

1 stop14h 20mAmerican Airlines

Thu 10/28:20 amGYE - STL

1 stop15h 39mAmerican Airlines

Deal found 9/15

$952

Mon 9/291:30 pmSTL - GYE

3 stops33h 10mMultiple Airlines

Wed 10/13:15 amGYE - STL

3 stops32h 14mMultiple Airlines

Deal found 9/15

$1,119

One-way flights from St. Louis to Guayaquil
Search for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 17, 2025.

Thu 11/1312:20 pmSTL - GYE

2 stops34h 15mMultiple Airlines

Deal found 9/16

$160

Sat 2/72:48 pmSTL - GYE

1 stop7h 57mSpirit Airlines

Deal found 9/15

$180

Mon 11/107:45 pmSTL - GYE

3 stops32h 50mMultiple Airlines

Deal found 9/16

$257

Wed 11/127:45 pmSTL - GYE

3 stops26h 50mMultiple Airlines

Deal found 9/16

$345

Sat 2/76:40 pmSTL - GYE

2 stops13h 35mMultiple Airlines

Deal found 9/15

$370

Mon 11/106:15 amSTL - GYE

2 stops16h 26mUnited Airlines

Deal found 9/16

$371

Sat 2/76:00 amSTL - GYE

2 stops30h 34mUnited Airlines

Deal found 9/16

$380

Wed 11/126:15 amSTL - GYE

2 stops28h 03mUnited Airlines

Deal found 9/16

$394

Sat 2/75:02 pmSTL - GYE

1 stop28h 03mAmerican Airlines

Deal found 9/16

$447

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 2/19

12:20 pm-11:45 pm

1 stop10h 25m

Guayaquil Jose Joaquin de Olmedo

Sat 2/28

12:59 am-11:01 am

1 stop11h 02m

$577

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

6:15 am-11:18 am

2 stops28h 03m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

2:35 pm-10:46 am

2 stops21h 11m

$597

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 2/19

4:17 pm-11:18 am

2 stops42h 01m

Guayaquil Jose Joaquin de Olmedo

Sun 3/1

12:20 pm-10:14 pm

2 stops34h 54m

$615

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 2/19

5:11 pm-11:45 pm

2 stops53h 34m

Guayaquil Jose Joaquin de Olmedo

Sat 2/28

12:59 am-11:01 am

1 stop11h 02m

$643

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 2/19

5:19 am-1:33 pm

1 stop7h 14m

Guayaquil Jose Joaquin de Olmedo

Sun 3/1

2:33 pm-11:46 pm

1 stop10h 13m

$753

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Mon 9/29

6:15 am-11:15 am

2 stops29h 00m

Guayaquil Jose Joaquin de Olmedo

Wed 10/1

3:15 am-10:00 pm

2 stops18h 45m

$851

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 12/4

5:10 am-11:06 pm

1 stop16h 56m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

2:33 pm-11:46 pm

1 stop10h 13m

$902

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Mon 9/29

5:28 am-7:48 pm

1 stop14h 20m

Guayaquil Jose Joaquin de Olmedo

Thu 10/2

8:20 am-11:59 pm

1 stop15h 39m

$952

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Thu 11/13

12:20 pm-11:35 pm

2 stops34h 15m

$160

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 2/7

2:48 pm-11:45 pm

1 stop7h 57m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 17 results

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

How long is the flight from St. Louis to Guayaquil?
For as low as $577, Spirit Airlines can have you in Guayaquil from St. Louis in 10h 25m. Airlines will cover a distance of 2902 mi. This flight may include one or multiple stops.
What is the cheapest airline to fly from St. Louis to Guayaquil round-trip?
American Airlines, at $516, was found to be the cheapest airline from St. Louis to Guayaquil..
Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?
Yes. In addition to deals on St. Louis to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Guayaquil?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Guayaquil.
Can I find deals for business class flights from St. Louis to Guayaquil?
Yes. Cheapflights offers flight deals from St. Louis to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Guayaquil?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Guayaquil (average of $440). Flying from St. Louis to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for St. Louis to Guayaquil

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Other flights to Guayaquil

Top airline flying from St. Louis to Guayaquil

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$516	Average$996	FlexibilityNo cancel fee	On-time71%

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$160+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Guayaquil with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from St. Louis to Guayaquil

Round-trip from

One-way from

Find flight deals from St. Louis to Guayaquil

Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.

Best time to book a flight from St. Louis to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.

Reviews of airlines servicing Guayaquil

See what other customers who have flown with American Airlines from St. Louis to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from St. Louis to Guayaquil?

What is the cheapest airline to fly from St. Louis to Guayaquil round-trip?

Can I find deals for flights from St. Louis to Guayaquil that include hotel bookings?

How can I find direct flights from St. Louis to Guayaquil?

Can I find deals for business class flights from St. Louis to Guayaquil?

What is the cheapest month to book a flight from St. Louis to Guayaquil?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from St. Louis to Guayaquil

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Book with Flexibility

Travel Smart

Cheapest flights from St. Louis to Guayaquil
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.