$569+ Cheap flights from St. Louis (STL) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Nov 30 — Dec 71
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guayaquil
Cheapest
Best
One-way
Cheapest flights from St. Louis to GuayaquilExplore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
Explore the most affordable flight options available from St. Louis to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/216:00 am -
2 stops18h 25m
Deal found 10/27![American Airlines logo]()
$907
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:30 am -
2 stops32h 06m
Mon 12/218:25 am -
2 stops39h 05m
Deal found 10/27![United Airlines logo]()
$939
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:15 am -
2 stops13h 42m
Tue 1/1212:22 pm -
2 stops22h 09m
Deal found 10/30![Copa Airlines logo]()
$1,005
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:46 pm -
2 stops20h 44m
Wed 12/303:30 pm -
2 stops19h 49m
Deal found 10/27![American Airlines logo]()
$1,037
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:15 am -
2 stops16h 26m
Wed 12/308:25 am -
2 stops15h 05m
Deal found 10/30![Copa Airlines logo]()
$1,040
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:57 pm -
2 stops18h 33m
Tue 1/126:00 am -
1 stop12h 26m
Deal found 10/29![American Airlines logo]()
$1,101
Best flights from St. Louis to GuayaquilDiscover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
Discover carefully curated flight deals from St. Louis to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:06 pm -
1 stop19h 42m
Mon 1/186:00 am -
1 stop17h 42m
Deal found 10/27![American Airlines logo]()
$803
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:30 am -
2 stops32h 06m
Mon 12/218:25 am -
2 stops39h 05m
Deal found 10/27![United Airlines logo]()
$939
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:15 am -
2 stops13h 42m
Tue 1/1212:22 pm -
2 stops22h 09m
Deal found 10/30![Copa Airlines logo]()
$1,005
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 pm -
1 stop19h 16m
Mon 12/216:00 am -
2 stops18h 25m
Deal found 10/27![American Airlines logo]()
$907
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:15 am -
2 stops16h 28m
Wed 1/272:44 pm -
2 stops32h 46m
Deal found 10/30![United Airlines logo]()
$1,060
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:46 pm -
2 stops20h 44m
Wed 12/303:30 pm -
2 stops19h 49m
Deal found 10/29![American Airlines logo]()
$1,037
One-way flights from St. Louis to GuayaquilSearch for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
Search for one-way flight options from St. Louis to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
This KAYAK deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:15 am -
2 stops16h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Copa Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/275:03 am -
1 stop17h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$725
Find flight deals from St. Louis to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 31, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $732 (American Airlines) |
One-way from | $569 (KAYAK) |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
Use the filters below to find and compare flights from St. Louis to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 12/27
6:15 am-11:41 pm
2 stops16h 26m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$569
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 12/27
5:03 am-11:55 pm
1 stop17h 52m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$725
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Fri 1/8
6:06 pm-2:48 pm
1 stop19h 42m
Guayaquil Jose Joaquin de Olmedo
Mon 1/18
6:00 am-10:42 pm
1 stop17h 42m
$803
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sat 12/12
6:15 pm-2:31 pm
1 stop19h 16m
Guayaquil Jose Joaquin de Olmedo
Mon 12/21
6:00 am-11:25 pm
2 stops18h 25m
$907
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sat 12/12
8:30 am-5:36 pm
2 stops32h 06m
Guayaquil Jose Joaquin de Olmedo
Mon 12/21
8:25 am-10:30 pm
2 stops39h 05m
$939
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 12/27
6:15 am-8:57 pm
2 stops13h 42m
Guayaquil Jose Joaquin de Olmedo
Tue 1/12
12:22 pm-9:31 am
2 stops22h 09m
$1,005
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Sun 12/20
4:46 pm-2:30 pm
2 stops20h 44m
Guayaquil Jose Joaquin de Olmedo
Wed 12/30
3:30 pm-10:19 am
2 stops19h 49m
$1,037
St. LouisGuayaquil
STL Lambert-St Louis - GYE Guayaquil Jose Joaquin de Olmedo
STLGYE
Lambert-St Louis
Mon 1/25
6:15 am-11:43 pm
2 stops16h 28m
Guayaquil Jose Joaquin de Olmedo
Wed 1/27
2:44 pm-10:30 pm
2 stops32h 46m
$1,060
Sorted by cheapest first
- Most accurate provider: When it comes to deals on St. Louis-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on St. Louis-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from St. Louis-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from St. Louis with our price prediction graph.
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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