$101+ Cheap flights from O'Hare Intl (ORD) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GYE
Mar 11 — Mar 181
1 adult, Economy
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1. Tell us where you want to go
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Cheapest flights from O'Hare Intl to GuayaquilExplore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.
Explore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.
This Avianca deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2211:20 pm
ORD
- GYE
1 stop15h 15m
Avianca
Sun 5/3110:05 am
GYE
- ORD
1 stop11h 15m
Avianca
Deal found 2/7![Avianca logo]()
$358
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:21 pm
ORD
- GYE
1 stop8h 17m
Copa Airlines
Thu 4/306:00 am
GYE
- ORD
1 stop19h 13m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$359
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/284:43 pm
ORD
- GYE
1 stop30h 21m
Spirit Airlines
Fri 3/612:59 am
GYE
- ORD
1 stop19h 12m
Spirit Airlines
Deal found 2/8![Spirit Airlines logo]()
$362
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:20 pm
ORD
- GYE
2 stops27h 41m
Spirit Airlines
Wed 5/2011:59 pm
GYE
- ORD
1 stop19h 49m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:21 pm
ORD
- GYE
1 stop31h 43m
Multiple Airlines
Mon 3/26:55 pm
GYE
- ORD
2 stops41h 27m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$367
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:42 pm
ORD
- GYE
2 stops26h 22m
Spirit Airlines
Mon 3/1611:59 pm
GYE
- ORD
2 stops16h 57m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:10 am
ORD
- GYE
2 stops13h 34m
American Airlines
Thu 4/92:31 pm
GYE
- ORD
1 stop20h 33m
American Airlines
Deal found 2/8![American Airlines logo]()
$369
This CheapOair deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:41 am
ORD
- GYE
2 stops39h 20m
Spirit Airlines
Wed 4/2911:59 pm
GYE
- ORD
2 stops18h 41m
Spirit Airlines
Deal found 2/6![Spirit Airlines logo]()
$372
This Avianca deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:20 pm
ORD
- GYE
1 stop15h 10m
Avianca
Tue 3/319:10 am
GYE
- ORD
1 stop12h 10m
Avianca
Deal found 2/6![Avianca logo]()
$374
This Expedia deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:05 am
ORD
- GYE
1 stop17h 59m
Spirit Airlines
Sun 3/1511:59 pm
GYE
- ORD
2 stops16h 57m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$375
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:21 pm
ORD
- GYE
1 stop8h 40m
Copa Airlines
Tue 6/304:28 am
GYE
- ORD
1 stop9h 38m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:52 pm
ORD
- GYE
2 stops17h 03m
Multiple Airlines
Sat 5/3010:05 am
GYE
- ORD
1 stop11h 15m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$377
Best flights from O'Hare Intl to GuayaquilDiscover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.
Discover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.
This CheapOair deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:42 pm
ORD
- GYE
2 stops26h 22m
Spirit Airlines
Mon 3/1611:59 pm
GYE
- ORD
2 stops16h 57m
Spirit Airlines
Deal found 2/6![Spirit Airlines logo]()
$358
This Avianca deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2211:20 pm
ORD
- GYE
1 stop18h 15m
Avianca
Sun 5/314:05 am
GYE
- ORD
1 stop17h 15m
Avianca
Deal found 2/8![Avianca logo]()
$358
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:21 pm
ORD
- GYE
1 stop8h 17m
Copa Airlines
Thu 4/306:00 am
GYE
- ORD
1 stop19h 13m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$359
This CheapOair deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:20 pm
ORD
- GYE
2 stops27h 41m
Spirit Airlines
Wed 5/2011:59 pm
GYE
- ORD
1 stop19h 49m
Spirit Airlines
Deal found 2/9![Spirit Airlines logo]()
$364
This Avianca deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:20 pm
ORD
- GYE
1 stop15h 10m
Avianca
Tue 3/319:10 am
GYE
- ORD
1 stop12h 10m
Avianca
Deal found 2/7![Avianca logo]()
$374
This Copa Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:02 am
ORD
- GYE
1 stop15h 59m
Copa Airlines
Fri 6/195:59 am
GYE
- ORD
1 stop19h 16m
Copa Airlines
Deal found 2/7![Copa Airlines logo]()
$376
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:31 pm
ORD
- GYE
2 stops27h 33m
Spirit Airlines
Wed 4/2211:59 pm
GYE
- ORD
2 stops18h 41m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$368
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:21 pm
ORD
- GYE
1 stop8h 40m
Copa Airlines
Mon 6/226:27 pm
GYE
- ORD
1 stop19h 39m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$376
This Expedia deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:05 am
ORD
- GYE
1 stop17h 59m
Spirit Airlines
Sun 3/1511:59 pm
GYE
- ORD
2 stops16h 57m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$375
This Copa Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:02 am
ORD
- GYE
1 stop12h 49m
Copa Airlines
Tue 6/304:28 am
GYE
- ORD
1 stop9h 38m
Copa Airlines
Deal found 2/6![Copa Airlines logo]()
$376
Last-minute flights from O'Hare Intl to GuayaquilDiscover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated February 9, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated February 9, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:20 am
ORD
- GYE
1 stop16h 01m
Spirit Airlines
Tue 3/1011:59 pm
GYE
- ORD
1 stop11h 23m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$376
This Avianca deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:20 pm
ORD
- GYE
1 stop18h 25m
Avianca
Wed 2/253:30 am
GYE
- ORD
1 stop17h 50m
Avianca
Deal found 2/7![Avianca logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:34 am
ORD
- GYE
1 stop26h 44m
Copa Airlines
Sat 2/2812:20 pm
GYE
- ORD
1 stop12h 44m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$383
This Avianca deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:20 pm
ORD
- GYE
1 stop15h 05m
Avianca
Wed 2/256:55 pm
GYE
- ORD
1 stop26h 25m
Avianca
Deal found 2/6![Avianca logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:21 pm
ORD
- GYE
1 stop31h 43m
Multiple Airlines
Mon 3/26:55 pm
GYE
- ORD
2 stops41h 27m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$367
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/284:43 pm
ORD
- GYE
1 stop30h 21m
Spirit Airlines
Fri 3/612:59 am
GYE
- ORD
1 stop19h 12m
Spirit Airlines
Deal found 2/8![Spirit Airlines logo]()
$362
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:42 pm
ORD
- GYE
2 stops26h 22m
Spirit Airlines
Mon 3/1611:59 pm
GYE
- ORD
2 stops16h 57m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:10 am
ORD
- GYE
2 stops13h 34m
American Airlines
Thu 4/92:31 pm
GYE
- ORD
1 stop20h 33m
American Airlines
Deal found 2/8![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:36 pm
ORD
- GYE
1 stop28h 28m
Multiple Airlines
Sat 4/1111:59 pm
GYE
- ORD
2 stops34h 51m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$379
This Expedia deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:05 am
ORD
- GYE
1 stop17h 59m
Spirit Airlines
Sun 3/1511:59 pm
GYE
- ORD
2 stops16h 57m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$375
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:20 pm
ORD
- GYE
1 stop18h 25m
Avianca
Tue 3/314:05 am
GYE
- ORD
1 stop17h 15m
Avianca
Deal found 2/9![Avianca logo]()
$374
One-way flights from O'Hare Intl to GuayaquilSearch for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 9, 2026.
Search for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 9, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:15 am
ORD
- GYE
1 stop17h 46m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$101
This Cheapflightsfares deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:15 am
ORD
- GYE
1 stop17h 46m
Spirit Airlines
Deal found 2/8![Spirit Airlines logo]()
$113
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:52 pm
ORD
- GYE
1 stop13h 28m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:27 pm
ORD
- GYE
1 stop33h 34m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:15 pm
ORD
- GYE
2 stops13h 40m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:15 pm
ORD
- GYE
1 stop10h 05m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:34 pm
ORD
- GYE
2 stops24h 16m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$145
This Avianca deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:20 pm
ORD
- GYE
1 stop9h 55m
Avianca
Deal found 2/6![Avianca logo]()
$146
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:34 am
ORD
- GYE
1 stop12h 12m
Copa Airlines
Deal found 2/8![Copa Airlines logo]()
$148
Find flight deals from O'Hare Intl to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $358 (Avianca) |
One-way from | $101 (Cheapflightsfares) |
Popular in | December |
Cheapest in | January |
Average price | $501 |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Guayaquil that are best for you.
Fly from
O'Hare Intl
Fly to
Guayaquil
Route
Depart
Return
Price
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Mon 3/9
8:42 pm-11:04 pm
2 stops26h 22m
Guayaquil Jose Joaquin de Olmedo
Mon 3/16
11:59 pm-4:56 pm
2 stops16h 57m
$358
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Fri 5/22
11:20 pm-5:35 pm
1 stop18h 15m
Guayaquil Jose Joaquin de Olmedo
Sun 5/31
4:05 am-9:20 pm
1 stop17h 15m
$358
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Wed 4/1
3:21 pm-11:38 pm
1 stop8h 17m
Guayaquil Jose Joaquin de Olmedo
Thu 4/30
6:00 am-1:13 am
1 stop19h 13m
$359
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Fri 4/24
7:20 pm-11:01 pm
2 stops27h 41m
Guayaquil Jose Joaquin de Olmedo
Wed 5/20
11:59 pm-7:48 pm
1 stop19h 49m
$364
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Wed 4/8
7:31 pm-11:04 pm
2 stops27h 33m
Guayaquil Jose Joaquin de Olmedo
Wed 4/22
11:59 pm-6:40 pm
2 stops18h 41m
$368
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Wed 3/25
11:20 pm-2:30 pm
1 stop15h 10m
Guayaquil Jose Joaquin de Olmedo
Tue 3/31
9:10 am-9:20 pm
1 stop12h 10m
$374
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 3/12
5:05 am-11:04 pm
1 stop17h 59m
Guayaquil Jose Joaquin de Olmedo
Sun 3/15
11:59 pm-4:56 pm
2 stops16h 57m
$375
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Fri 6/12
8:02 am-12:01 am
1 stop15h 59m
Guayaquil Jose Joaquin de Olmedo
Fri 6/19
5:59 am-1:15 am
1 stop19h 16m
$376
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Tue 6/16
3:21 pm-12:01 am
1 stop8h 40m
Guayaquil Jose Joaquin de Olmedo
Mon 6/22
6:27 pm-2:06 pm
1 stop19h 39m
$376
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 6/4
8:02 am-8:51 pm
1 stop12h 49m
Guayaquil Jose Joaquin de Olmedo
Tue 6/30
4:28 am-2:06 pm
1 stop9h 38m
$376
Showing 1-10 of 17 results
Compare providers for flights from O'Hare Intl to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Guayaquil in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from O'Hare Intl with our price prediction graph.
ORD-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Guayaquil
Prices
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How far ahead should I book a flight from Chicago O'Hare Intl Airport to Guayaquil?
Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Guayaquil. Price data was last updated on February 6, 2026.
To ensure you get the cheapest price possible for a flight from Chicago O'Hare Intl Airport to Guayaquil, you should look to book at least 72 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?
Currently, June is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Guayaquil (average of $212). Flying from Chicago O'Hare Intl Airport to Guayaquil in December is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?
Share of 1-stop round-trip flights from Chicago O'Hare Intl Airport to Guayaquil chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 71% of 1-stop itineraries from Chicago O'Hare Intl Airport to Guayaquil on Cheapflights.
What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?
Average round-trip fare for 1-stop flights from Chicago O'Hare Intl Airport to Guayaquil, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $594.
What’s the fastest layover option from Chicago O'Hare Intl Airport to Guayaquil?
Shortest average travel time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Guayaquil, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 8h 48m.
Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Guayaquil?
Average layover duration for 1-stop one-way flights from Chicago O'Hare Intl Airport to Guayaquil, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 17m.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated February 9, 2026.
Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Guayaquil, such as Copa Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Search flights from O'Hare Intl to Guayaquil by cabin class
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 9, 2026.
O'Hare Intl and Guayaquil flights
Browse other O'Hare Intl and Guayaquil flight options. Last updated on February 9, 2026.
Other flights from O'Hare Intl
Browse through other flights departing from O'Hare Intl. Flights are based on user searches made on Cheapflights and were last updated on February 9, 2026.
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Top 4 airlines flying from O'Hare Intl to Guayaquil
Discover the top 4 airlines that operate flights from O'Hare Intl to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$344 | Average$528 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$369 | Average$569 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$387 | Average$777 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$438 | Average$517 | FlexibilityNo cancel fee | On-time69% |