What’s the fastest layover option from Chicago O'Hare Intl Airport to Guayaquil?

Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 9h 37m.

What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?

Panama City (PTY) – chosen by Cheapflights users on 58% of 1-stop itineraries from Chicago O'Hare Intl Airport to Guayaquil on Cheapflights.

Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Guayaquil?

Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 38m.

What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?

Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $727.

How long is the flight from Chicago O'Hare Intl Airport to Guayaquil?

A quick flight from Chicago O'Hare Intl Airport to Guayaquil can take about 9h 03m. Copa Airlines provides one of the quickest options available for as low as $439. The distance from Chicago O'Hare Intl Airport to Guayaquil is about 3089 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Guayaquil round-trip?

Cheapflights users have booked flights from Chicago O'Hare Intl Airport to Guayaquil round-trip from $198. Other airlines that can offer you cheap pricing are Avianca, from $313, and Copa Airlines, from $354. Spirit Airlines is 63% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Guayaquil one-way?

The cheapest airlines for a one-way flight from Chicago O'Hare Intl Airport to Guayaquil are Avianca ($162), Copa Airlines ($179), and United Airlines ($187).

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

What are the most popular airlines that fly from Chicago O'Hare Intl Airport to Guayaquil?

Before booking your flight from Chicago O'Hare Intl Airport to Guayaquil check out the most popular airlines for this route: Copa Airlines, Avianca or United Airlines.

Most accurate provider : When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Chicago O'Hare Intl Airport-Guayaquil flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Guayaquil flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly into for flights to Guayaquil from Chicago O'Hare Intl?

If you book a flight to Guayaquil from Chicago O'Hare Intl, you will be flying to Jose Joaquin de Olmedo, which is the city’s only airport. Guayaquil Jose Joaquin de Olmedo (GYE) is located 2.5 mi from the center of Guayaquil. There are 0 flights from Chicago O'Hare Intl to Jose Joaquin de Olmedo per day from 5 different airlines.

Can I find deals for flights from O'Hare Intl to Guayaquil that include hotel bookings?

Yes. In addition to deals on O'Hare Intl to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from O'Hare Intl to Guayaquil?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Guayaquil.

Can I find deals for business class flights from O'Hare Intl to Guayaquil?

Yes. Cheapflights offers flight deals from O'Hare Intl to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$79+ Flights from Chicago O'Hare Intl Airport to Guayaquil

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Guayaquil Jose Joaquin de Olmedo are usually found in October or January, booked 26 days in advance, depart on a Sunday or Wednesday and return on a Saturday

Cheap flight deals from O'Hare Intl to Guayaquil

Cheapest flights from O'Hare Intl to Guayaquil
Explore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Mon 12/157:33 amORD - GYE

1 stop9h 03mCopa Airlines

Tue 12/1612:20 pmGYE - ORD

1 stop12h 45mCopa Airlines

Deal found 12/11

$439

Wed 12/317:30 amORD - GYE

1 stop15h 23mSpirit Airlines

Sat 1/101:26 amGYE - ORD

1 stop10h 56mSpirit Airlines

Deal found 12/10

$495

Fri 12/127:33 amORD - GYE

1 stop9h 03mCopa Airlines

Wed 12/172:35 pmGYE - ORD

1 stop10h 30mCopa Airlines

Deal found 12/11

$543

Sat 12/134:10 pmORD - GYE

2 stops15h 50mAvianca

Tue 12/163:30 amGYE - ORD

1 stop17h 50mAvianca

Deal found 12/11

$570

Mon 12/157:33 amORD - GYE

1 stop9h 03mMultiple Airlines

Tue 12/1610:25 amGYE - ORD

1 stop10h 55mMultiple Airlines

Deal found 12/11

$603

Mon 12/157:33 amORD - GYE

1 stop12h 10mCopa Airlines

Tue 12/302:35 pmGYE - ORD

1 stop10h 30mCopa Airlines

Deal found 12/9

$605

Mon 12/225:00 amORD - GYE

1 stop17h 53mSpirit Airlines

Tue 1/201:26 amGYE - ORD

1 stop10h 56mSpirit Airlines

Deal found 12/9

$612

Best flights from O'Hare Intl to Guayaquil
Discover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Mon 1/126:45 amORD - GYE

2 stops21h 31mMultiple Airlines

Fri 2/2012:59 amGYE - ORD

2 stops19h 46mMultiple Airlines

Deal found 12/10

$437

Mon 12/157:33 amORD - GYE

1 stop9h 03mCopa Airlines

Tue 12/1612:20 pmGYE - ORD

1 stop12h 45mCopa Airlines

Deal found 12/11

$439

Thu 3/55:40 amORD - GYE

2 stops17h 01mUnited Airlines

Thu 3/1212:20 pmGYE - ORD

2 stops12h 06mUnited Airlines

Deal found 12/10

$448

Thu 1/85:45 amORD - GYE

2 stops17h 36mSpirit Airlines

Wed 1/141:26 amGYE - ORD

2 stops19h 15mSpirit Airlines

Deal found 12/11

$473

Tue 1/610:20 pmORD - GYE

1 stop18h 25mAvianca

Thu 1/159:05 amGYE - ORD

1 stop12h 15mAvianca

Deal found 12/10

$505

Mon 12/157:33 amORD - GYE

1 stop9h 03mCopa Airlines

Tue 12/302:35 pmGYE - ORD

1 stop10h 30mCopa Airlines

Deal found 12/11

$439

Fri 2/2010:07 amORD - GYE

3 stops36h 57mSpirit Airlines

Sun 2/2212:59 amGYE - ORD

3 stops19h 46mSpirit Airlines

Deal found 12/11

$478

Mon 1/128:52 amORD - GYE

2 stops13h 43mAvianca

Tue 1/279:05 amGYE - ORD

1 stop12h 15mAvianca

Deal found 12/11

$510

Tue 1/67:57 pmORD - GYE

2 stops26h 56mSpirit Airlines

Mon 1/121:26 amGYE - ORD

3 stops22h 12mSpirit Airlines

Deal found 12/9

$483

Thu 2/195:15 amORD - GYE

1 stop17h 49mSpirit Airlines

Mon 2/2312:59 amGYE - ORD

2 stops17h 13mSpirit Airlines

Deal found 12/11

$514

Tue 1/67:30 amORD - GYE

1 stop15h 23mSpirit Airlines

Wed 1/141:26 amGYE - ORD

2 stops19h 15mSpirit Airlines

Deal found 12/11

$538

Last-minute flights from O'Hare Intl to Guayaquil
Discover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated December 12, 2025 and is based on user searches.

Mon 12/157:33 amORD - GYE

1 stop9h 03mCopa Airlines

Tue 12/1612:20 pmGYE - ORD

1 stop12h 45mCopa Airlines

Deal found 12/11

$439

Wed 12/317:30 amORD - GYE

1 stop15h 23mSpirit Airlines

Sat 1/101:26 amGYE - ORD

1 stop10h 56mSpirit Airlines

Deal found 12/10

$495

Tue 1/67:57 pmORD - GYE

2 stops26h 56mSpirit Airlines

Wed 1/141:26 amGYE - ORD

1 stop10h 56mSpirit Airlines

Deal found 12/10

$449

Tue 1/67:57 pmORD - GYE

2 stops26h 56mSpirit Airlines

Mon 1/121:26 amGYE - ORD

3 stops22h 12mSpirit Airlines

Deal found 12/9

$483

Tue 1/610:20 pmORD - GYE

1 stop18h 25mAvianca

Thu 1/159:05 amGYE - ORD

1 stop12h 15mAvianca

Deal found 12/10

$505

Thu 1/85:45 amORD - GYE

2 stops17h 36mSpirit Airlines

Tue 1/131:26 amGYE - ORD

3 stops22h 12mSpirit Airlines

Deal found 12/9

$432

Thu 1/85:45 amORD - GYE

2 stops17h 36mSpirit Airlines

Wed 1/141:26 amGYE - ORD

2 stops19h 15mSpirit Airlines

Deal found 12/11

$473

Mon 1/126:45 amORD - GYE

2 stops21h 31mMultiple Airlines

Fri 2/2012:59 amGYE - ORD

2 stops19h 46mMultiple Airlines

Deal found 12/10

$437

Mon 1/128:52 amORD - GYE

2 stops13h 43mAvianca

Tue 1/279:05 amGYE - ORD

1 stop12h 15mAvianca

Deal found 12/11

$510

One-way flights from O'Hare Intl to Guayaquil
Search for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Mon 1/127:20 amORD - GYE

1 stop16h 01mSpirit Airlines

Deal found 12/10

$79

Sun 1/117:20 amORD - GYE

1 stop16h 01mSpirit Airlines

Deal found 12/10

$85

Fri 1/98:43 pmORD - GYE

1 stop26h 38mSpirit Airlines

Deal found 12/10

$89

Sat 1/105:32 pmORD - GYE

1 stop29h 49mSpirit Airlines

Deal found 12/10

$98

Thu 1/85:15 amORD - GYE

1 stop18h 06mSpirit Airlines

Deal found 12/10

$122

Thu 1/85:50 amORD - GYE

2 stops17h 31mMultiple Airlines

Deal found 12/10

$133

Mon 1/1210:37 pmORD - GYE

3 stops48h 44mMultiple Airlines

Deal found 12/10

$145

Find flight deals from O'Hare Intl to Guayaquil

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$432 (Mytrip)
One-way from	$79 (Cheapflightsfares)
Popular in	March
Cheapest in	October
Average price	$670

Provider with most accurate pricing for Chicago O'Hare Intl-Guayaquil Jose Joaquin de Olmedo flight deals.

Search Deals

Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Guayaquil Jose Joaquin de Olmedo flights.

Search Deals

From Chicago O'Hare Intl to Guayaquil Jose Joaquin de Olmedo

Search Deals

One-way flight from Chicago O'Hare Intl to Guayaquil Jose Joaquin de Olmedo

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($42 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Mon 1/12

6:45 am-5:16 am

2 stops21h 31m

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

12:59 am-7:45 pm

2 stops19h 46m

$437

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Mon 12/15

7:33 am-5:36 pm

1 stop9h 03m

Guayaquil Jose Joaquin de Olmedo

Tue 12/16

12:20 pm-12:05 am

1 stop12h 45m

$439

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Mon 12/15

7:33 am-5:36 pm

1 stop9h 03m

Guayaquil Jose Joaquin de Olmedo

Tue 12/30

2:35 pm-12:05 am

1 stop10h 30m

$439

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Thu 3/5

5:40 am-11:41 pm

2 stops17h 01m

Guayaquil Jose Joaquin de Olmedo

Thu 3/12

12:20 pm-12:26 am

2 stops12h 06m

$448

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Thu 1/8

5:45 am-12:21 am

2 stops17h 36m

Guayaquil Jose Joaquin de Olmedo

Wed 1/14

1:26 am-7:41 pm

2 stops19h 15m

$473

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Fri 2/20

10:07 am-12:04 am

3 stops36h 57m

Guayaquil Jose Joaquin de Olmedo

Sun 2/22

12:59 am-7:45 pm

3 stops19h 46m

$478

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Tue 1/6

7:57 pm-11:53 pm

2 stops26h 56m

Guayaquil Jose Joaquin de Olmedo

Mon 1/12

1:26 am-10:38 pm

3 stops22h 12m

$483

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Tue 1/6

10:20 pm-5:45 pm

1 stop18h 25m

Guayaquil Jose Joaquin de Olmedo

Thu 1/15

9:05 am-8:20 pm

1 stop12h 15m

$505

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Mon 1/12

8:52 am-11:35 pm

2 stops13h 43m

Guayaquil Jose Joaquin de Olmedo

Tue 1/27

9:05 am-8:20 pm

1 stop12h 15m

$510

ChicagoGuayaquil

ORD - GYE

ORDGYE

Chicago O'Hare Intl

Thu 2/19

5:15 am-12:04 am

1 stop17h 49m

Guayaquil Jose Joaquin de Olmedo

Mon 2/23

12:59 am-5:12 pm

2 stops17h 13m

$514

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 23 results

Compare providers for flights from O'Hare Intl to Guayaquil

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Guayaquil in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Ovago	Price Accuracy2 stars	Trust Score*2 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars
oojo	Price Accuracy3 stars	Trust Score*3 stars
Gotogate	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy2 stars	Trust Score*3 stars
CheapTicketsDeal	Price Accuracy3 stars	Trust Score*3 stars
Kiwi.com	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Chicago O'Hare Intl Airport-Guayaquil flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Guayaquil flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from O'Hare Intl with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Guayaquil

Prices

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Guayaquil?

To ensure you get the cheapest price possible for a flight from Chicago O'Hare Intl Airport to Guayaquil, you should look to book at least 26 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?

Currently, June is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Guayaquil (average of $209). Flying from Chicago O'Hare Intl Airport to Guayaquil in December is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to GYE?

Unlike in the afternoon, when flights are generally more expensive, you can save up to 34% on flights from Chicago O'Hare Intl Airport to Guayaquil by exploring options for tickets in the evening.

Reviews of airlines servicing Guayaquil

Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Guayaquil, such as Copa Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

4.0

Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Copa Airlines

7.6

Good

1,558 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

4.0

Okay

Juan Pablo,Sep 2025

PTY - VVI

United Airlines

7.4

Good

9,093 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

4.0

Okay

Juan Pablo,Sep 2025

PTY - VVI

American Airlines

7.2

Good

11,049 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

4.0

Okay

Juan Pablo,Sep 2025

PTY - VVI

Avianca

6.6

Okay

2,480 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

4.0

Okay

Juan Pablo,Sep 2025

PTY - VVI

Spirit Airlines

6.3

Okay

8,178 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

4.0

Okay

Juan Pablo,Sep 2025

PTY - VVI

Related info for your journey

What airport do you fly into for flights to Guayaquil from Chicago O'Hare Intl?
If you book a flight to Guayaquil from Chicago O'Hare Intl, you will be flying to Jose Joaquin de Olmedo, which is the city’s only airport. Guayaquil Jose Joaquin de Olmedo (GYE) is located 2.5 mi from the center of Guayaquil. There are 0 flights from Chicago O'Hare Intl to Jose Joaquin de Olmedo per day from 5 different airlines.
How long is the flight from Chicago O'Hare Intl Airport to Guayaquil?
A quick flight from Chicago O'Hare Intl Airport to Guayaquil can take about 9h 03m. Copa Airlines provides one of the quickest options available for as low as $439. The distance from Chicago O'Hare Intl Airport to Guayaquil is about 3089 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Guayaquil round-trip?
Cheapflights users have booked flights from Chicago O'Hare Intl Airport to Guayaquil round-trip from $198. Other airlines that can offer you cheap pricing are Avianca, from $313, and Copa Airlines, from $354. Spirit Airlines is 63% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Guayaquil one-way?
The cheapest airlines for a one-way flight from Chicago O'Hare Intl Airport to Guayaquil are Avianca ($162), Copa Airlines ($179), and United Airlines ($187).
Can I find deals for flights from O'Hare Intl to Guayaquil that include hotel bookings?
Yes. In addition to deals on O'Hare Intl to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from O'Hare Intl to Guayaquil?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Guayaquil.
Can I find deals for business class flights from O'Hare Intl to Guayaquil?
Yes. Cheapflights offers flight deals from O'Hare Intl to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?
Currently, June is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Guayaquil (average of $209). Flying from Chicago O'Hare Intl Airport to Guayaquil in December is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for O'Hare Intl to Guayaquil

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Other flights to Guayaquil

Top 5 airlines flying from O'Hare Intl to Guayaquil

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$331	Average$660	FlexibilityNo cancel fee	On-time65%
Avianca	Cheapest$357	Average$531	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$390	Average$586	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$429	Average$482	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$440	Average$729	FlexibilityNo cancel fee	On-time71%

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$79+ Cheap flights from O'Hare Intl (ORD) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from O'Hare Intl to Guayaquil with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheapflights Tip: The best prices from Chicago O'Hare Intl to Guayaquil Jose Joaquin de Olmedo are usually found in October or January, booked 26 days in advance, depart on a Sunday or Wednesday and return on a Saturday

Cheap flight deals from O'Hare Intl to Guayaquil

Cheapest flights from O'Hare Intl to GuayaquilExplore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from O'Hare Intl to Guayaquil

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Guayaquil that are best for you.

Compare providers for flights from O'Hare Intl to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Guayaquil in December.

Best time to book a flight from O'Hare Intl to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from O'Hare Intl with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Guayaquil

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Guayaquil?

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?

What is the cheapest time of day to fly from ORD to GYE?

What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?

What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?

What’s the fastest layover option from Chicago O'Hare Intl Airport to Guayaquil?

Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Guayaquil?

Reviews of airlines servicing Guayaquil

Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Guayaquil, such as Copa Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Guayaquil from Chicago O'Hare Intl?

How long is the flight from Chicago O'Hare Intl Airport to Guayaquil?

What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Guayaquil round-trip?

What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Guayaquil one-way?

Can I find deals for flights from O'Hare Intl to Guayaquil that include hotel bookings?

How can I find direct flights from O'Hare Intl to Guayaquil?

Can I find deals for business class flights from O'Hare Intl to Guayaquil?

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?

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Alternative routes for O'Hare Intl to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from O'Hare Intl to Guayaquil

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Cheapest flights from O'Hare Intl to Guayaquil
Explore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.