$213+ Cheap flights from Chicago (CHI) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — GYE
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to Guayaquil
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Cheapest flights from Chicago to GuayaquilExplore the most affordable flight options available from Chicago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Chicago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
1 stop8h 29m
Fri 11/132:30 pm -
1 stop10h 06m
Deal found 9/22![JetBlue logo]()
$472
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:20 pm -
1 stop9h 35m
Mon 11/210:10 am -
1 stop11h 20m
Deal found 9/18![Avianca logo]()
$487
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:20 pm -
1 stop22h 13m
Fri 10/236:01 am -
1 stop18h 56m
Deal found 9/22![Copa Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:14 am -
1 stop16h 25m
Sat 10/172:29 pm -
1 stop17h 18m
Deal found 9/21![American Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:30 am -
2 stops13h 09m
Sun 11/83:34 pm -
1 stop10h 10m
Deal found 9/18![American Airlines logo]()
$502
This FlightHub deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:20 pm -
1 stop15h 15m
Wed 10/287:35 pm -
1 stop25h 55m
Deal found 9/21![Avianca logo]()
$511
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:20 pm -
1 stop20h 01m
Sat 10/1712:18 pm -
1 stop12h 39m
Deal found 9/19![Copa Airlines logo]()
$513
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:20 pm -
1 stop9h 35m
Mon 10/2610:10 am -
1 stop11h 20m
Deal found 9/19![Avianca logo]()
$570
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:13 pm -
1 stop22h 29m
Thu 12/1012:22 pm -
1 stop25h 24m
Deal found 9/20![Copa Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:20 pm -
1 stop20h 01m
Wed 10/289:05 am -
2 stops23h 51m
Deal found 9/21![Multiple Airlines logo]()
$582
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:01 am -
1 stop16h 00m
Sun 11/110:10 am -
1 stop11h 20m
Deal found 9/21![Multiple Airlines logo]()
$584
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:20 pm -
1 stop8h 41m
Fri 10/234:15 pm -
2 stops19h 17m
Deal found 9/21![Multiple Airlines logo]()
$592
Best flights from Chicago to GuayaquilDiscover carefully curated flight deals from Chicago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Chicago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:35 am -
1 stop9h 03m
Mon 2/16:33 pm -
1 stop19h 13m
Deal found 9/21![Copa Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/911:10 am -
2 stops19h 52m
Tue 3/164:00 pm -
2 stops20h 37m
Deal found 9/23![Delta logo]()
$522
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:16 am -
3 stops18h 59m
Sun 11/87:35 pm -
3 stops23h 12m
Deal found 9/19![Multiple Airlines logo]()
$875
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:35 am -
1 stop26h 43m
Sun 11/2912:25 pm -
1 stop25h 21m
Deal found 9/19![Copa Airlines logo]()
$489
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/317:35 am -
1 stop12h 24m
Sat 2/136:33 pm -
1 stop19h 13m
Deal found 9/19![Copa Airlines logo]()
$489
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:01 am -
1 stop16h 00m
Sun 10/182:33 pm -
1 stop23h 26m
Deal found 9/19![Copa Airlines logo]()
$489
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:13 pm -
1 stop8h 42m
Mon 11/92:47 pm -
1 stop22h 59m
Deal found 9/18![Copa Airlines logo]()
$489
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:13 pm -
1 stop20h 05m
Sun 11/292:47 pm -
1 stop22h 59m
Deal found 9/21![Copa Airlines logo]()
$489
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:13 pm -
1 stop20h 05m
Tue 11/244:22 am -
1 stop9h 24m
Deal found 9/20![Copa Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:29 pm -
2 stops13h 33m
Thu 11/265:00 pm -
2 stops19h 25m
Deal found 9/21![Delta logo]()
$811
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/212:13 pm -
1 stop22h 31m
Wed 2/312:21 pm -
1 stop25h 25m
Deal found 9/21![Copa Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:34 am -
2 stops20h 28m
Wed 11/255:00 pm -
2 stops19h 25m
Deal found 9/20![Delta logo]()
$811
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:13 pm -
1 stop22h 29m
Thu 12/1012:22 pm -
1 stop12h 49m
Deal found 9/22![Copa Airlines logo]()
$574
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:04 am -
2 stops19h 36m
Sun 11/88:00 pm -
2 stops21h 18m
Deal found 9/19![Delta logo]()
$1,123
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:20 pm -
1 stop8h 17m
Sat 10/172:33 pm -
1 stop23h 26m
Deal found 9/19![Copa Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:04 am -
2 stops19h 36m
Sun 11/88:00 pm -
2 stops21h 18m
Deal found 9/18![Delta logo]()
$1,123
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:49 pm -
2 stops18h 25m
Fri 10/234:15 pm -
2 stops18h 22m
Deal found 9/19![Delta logo]()
$1,175
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:27 pm -
2 stops17h 47m
Mon 11/25:00 pm -
2 stops20h 47m
Deal found 9/21![Delta logo]()
$1,179
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:19 pm -
2 stops14h 43m
Wed 11/115:00 pm -
2 stops18h 24m
Deal found 9/19![Delta logo]()
$1,217
Last-minute flights from Chicago to GuayaquilDiscover last-minute flight deals from Chicago to Guayaquil. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Guayaquil. Data last updated September 23, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:20 pm -
1 stop9h 35m
Mon 10/2610:10 am -
1 stop11h 20m
Deal found 9/19![Avianca logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:14 am -
1 stop16h 25m
Sat 10/172:29 pm -
1 stop17h 18m
Deal found 9/21![American Airlines logo]()
$497
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:20 pm -
1 stop20h 01m
Sat 10/1712:18 pm -
1 stop12h 39m
Deal found 9/19![Copa Airlines logo]()
$513
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:01 am -
1 stop16h 00m
Sun 11/110:10 am -
1 stop11h 20m
Deal found 9/21![Multiple Airlines logo]()
$584
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:01 am -
1 stop16h 00m
Sun 10/186:32 pm -
2 stops30h 25m
Deal found 9/19![Multiple Airlines logo]()
$625
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:20 pm -
1 stop22h 13m
Fri 10/236:01 am -
1 stop18h 56m
Deal found 9/22![Copa Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:20 pm -
1 stop8h 41m
Fri 10/234:15 pm -
2 stops19h 17m
Deal found 9/21![Multiple Airlines logo]()
$592
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:20 pm -
1 stop9h 35m
Mon 11/210:10 am -
1 stop11h 20m
Deal found 9/18![Avianca logo]()
$487
This FlightHub deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:20 pm -
1 stop15h 15m
Wed 10/287:35 pm -
1 stop25h 55m
Deal found 9/21![Avianca logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:20 pm -
1 stop20h 01m
Wed 10/289:05 am -
2 stops23h 51m
Deal found 9/21![Multiple Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:30 am -
2 stops13h 09m
Sun 11/83:34 pm -
1 stop10h 10m
Deal found 9/18![American Airlines logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:13 pm -
1 stop8h 48m
Sun 11/17:30 pm -
2 stops18h 16m
Deal found 9/21![Multiple Airlines logo]()
$629
One-way flights from Chicago to GuayaquilSearch for one-way flight options from Chicago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Chicago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
1 stop8h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![JetBlue logo]()
$213
This JetBlue deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop8h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![JetBlue logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:13 pm -
1 stop8h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Copa Airlines logo]()
$221
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:01 am -
1 stop16h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Copa Airlines logo]()
$222
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/181:00 pm -
2 stops18h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Delta logo]()
$225
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:50 am -
2 stops13h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:13 pm -
1 stop20h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Copa Airlines logo]()
$226
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:40 am -
2 stops12h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$230
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:29 am -
2 stops14h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$234
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:01 am -
1 stop15h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Copa Airlines logo]()
$246
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:35 am -
1 stop15h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Copa Airlines logo]()
$253
This Booking.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:45 am -
1 stop18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Arajet logo]()
$255
Find flight deals from Chicago to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $487 (Avianca) |
One-way from | $213 (Cheapflightsfares) |
Popular in | December |
Cheapest in | March |
Average price | $615 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Chicago to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Wed 11/25
7:35 am-11:18 am
1 stop26h 43m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$222
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Tue 10/13
8:01 am-12:01 am
1 stop16h 00m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$222
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Mon 10/19
3:20 pm-10:33 am
1 stop19h 13m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$222
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Wed 11/18
2:13 pm-11:18 am
1 stop20h 05m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$222
Quickest round-trip
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Fri 11/6
2:13 pm-11:55 pm
1 stop8h 42m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$222
ChicagoGuayaquil
MDW Chicago Midway - GYE Guayaquil Jose Joaquin de Olmedo
MDWGYE
Chicago Midway
Mon 1/18
1:00 pm-8:02 am
2 stops18h 02m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$225
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sat 10/24
8:01 am-11:37 pm
1 stop15h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$246
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Fri 12/11
2:13 pm-5:36 pm
1 stop26h 23m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$246
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sun 11/1
7:35 am-5:35 pm
1 stop9h 00m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$246
ChicagoGuayaquil
MDW Chicago Midway - GYE Guayaquil Jose Joaquin de Olmedo
MDWGYE
Chicago Midway
Tue 11/10
6:16 am-11:55 pm
2 stops16h 39m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$281
Showing 1-10 of 37 resultsSorted by cheapest first
Compare providers for flights from Chicago to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Chicago with our price prediction graph.
CHI-GYE
ORD-GYE
MDW-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Guayaquil
CHI-GYE
ORD-GYE
MDW-GYE
What is the cheapest month to book a flight from Chicago to Guayaquil?
Currently, April is the cheapest month in which you can book a flight from Chicago to Guayaquil (average of $415). Flying from Chicago to Guayaquil in December is currently the most expensive (average of $681). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Guayaquil?
Airfare is below average for this route at the moment.
Chicago to Guayaquil flights typically cost between $507 and $684 in November.The cheapest round-trip price found within the last 5 days was $472 on JetBlue (Nov 6-Nov 13).
What’s the top layover airport for flights from Chicago to Guayaquil?
Share of 1-stop round-trip flights from Chicago to Guayaquil chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 72% of 1-stop itineraries from Chicago to Guayaquil on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Guayaquil?
Average round-trip fare for 1-stop flights from Chicago to Guayaquil, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $413.
What’s the fastest layover option from Chicago to Guayaquil?
Shortest average travel time for 1-stop one-way flights from Chicago to Guayaquil, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 8h 41m.
Which airport typically offers the quickest layover for flights from Chicago to Guayaquil?
Average layover duration for 1-stop one-way flights from Chicago to Guayaquil, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 50m.
How far ahead should I book a flight from Chicago to Guayaquil?
To ensure you get the cheapest price possible for a flight from Chicago to Guayaquil, you should look to book at least 2 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 23, 2026.
Get a feel of what it's like to fly with Copa Airlines,JetBlue, andAmerican Airlines from Chicago to Guayaquil by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Crew
8.1
Overall
7.6
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Crew
8.1
Overall
7.6
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Crew
8.1
Overall
7.6
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Crew
8.1
Overall
7.6
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Crew
8.1
Overall
7.6
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.
Chicago and Guayaquil flights
Browse other Chicago and Guayaquil flight options. Last updated on September 23, 2026.
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Top 5 airlines flying from Chicago to Guayaquil
Discover the top 5 airlines that operate flights from Chicago to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$532 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$352 | Average$572 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$370 | Average$544 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$382 | Average$666 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$387 | Average$778 | FlexibilityNo cancel fee | On-time71% |