
Most accurate provider | Mytrip 3 stars |
|---|---|
Most trusted provider | Mytrip 3 stars |
Round-trip from | $396 (Kiwi.com) |
One-way from | $95 (Cheapflightsfares) |
Popular in | December |
Cheapest in | September |
Average price | $434 |
Fly from
Fly to
Route
Depart
Return
Price
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Sat 2/28
5:15 am-12:04 am
1 stop17h 49m
Guayaquil Jose Joaquin de Olmedo
Fri 3/6
12:59 am-7:47 pm
2 stops19h 48m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Sun 2/8
7:20 am-12:21 am
1 stop16h 01m
Guayaquil Jose Joaquin de Olmedo
Sun 2/15
12:59 am-5:46 pm
2 stops17h 47m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Sun 3/15
11:20 pm-2:25 pm
1 stop15h 05m
Guayaquil Jose Joaquin de Olmedo
Sun 3/22
6:50 pm-8:13 am
1 stop13h 23m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 2/19
7:00 am-12:04 am
1 stop16h 04m
Guayaquil Jose Joaquin de Olmedo
Sun 2/22
2:35 pm-12:31 pm
1 stop22h 56m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 2/19
7:00 am-12:04 am
1 stop16h 04m
Guayaquil Jose Joaquin de Olmedo
Mon 2/23
6:33 pm-12:31 pm
1 stop18h 58m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Wed 2/11
10:20 pm-9:15 am
1 stop9h 55m
Guayaquil Jose Joaquin de Olmedo
Sun 2/15
12:59 am-4:57 pm
2 stops40h 58m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Fri 3/6
7:46 pm-5:33 pm
2 stops20h 47m
Guayaquil Jose Joaquin de Olmedo
Thu 3/12
12:20 pm-7:46 am
2 stops19h 26m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 2/19
9:15 pm-8:46 pm
2 stops22h 31m
Guayaquil Jose Joaquin de Olmedo
Mon 2/23
12:20 pm-7:46 am
2 stops20h 26m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Wed 2/18
7:35 am-11:42 pm
2 stops15h 07m
Guayaquil Jose Joaquin de Olmedo
Mon 2/23
12:20 pm-12:26 am
2 stops13h 06m
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Wed 2/18
6:02 pm-12:04 am
2 stops29h 02m
Guayaquil Jose Joaquin de Olmedo
Sun 2/22
4:33 am-12:31 pm
1 stop8h 58m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
To ensure you get the cheapest price possible for a flight from Chicago to Guayaquil, you should look to book at least 83 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Currently, June is the cheapest month in which you can book a flight from Chicago to Guayaquil (average of $209). Flying from Chicago to Guayaquil in April is currently the most expensive (average of $432). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Panama City (PTY) – chosen by Cheapflights users on 68% of 1-stop itineraries from Chicago to Guayaquil on Cheapflights.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $645.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 8h 56m.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 18m.
Crew
Food
Overall
Entertainment
Boarding
Comfort
Reviews
Maria,Dec 2025
MIA - PTY
Crew
Food
Overall
Entertainment
Boarding
Comfort
Reviews
Maria,Dec 2025
MIA - PTY
Crew
Food
Overall
Entertainment
Boarding
Comfort
Reviews
Maria,Dec 2025
MIA - PTY
Crew
Food
Overall
Entertainment
Boarding
Comfort
Reviews
Maria,Dec 2025
MIA - PTY
Crew
Food
Overall
Entertainment
Boarding
Comfort
Reviews
Maria,Dec 2025
MIA - PTY
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$351 | Average$546 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$392 | Average$585 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$429 | Average$495 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$440 | Average$778 | FlexibilityNo cancel fee | On-time71% |