$203+ Cheap flights from Chicago (CHI) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — GYE
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to GuayaquilExplore the most affordable flight options available from Chicago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Chicago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:35 am -
1 stop12h 21m
Sun 11/222:47 pm -
1 stop10h 24m
Deal found 9/8![Copa Airlines logo]()
$453
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:01 am -
1 stop26h 32m
Sun 11/14:22 am -
1 stop9h 24m
Deal found 9/7![Copa Airlines logo]()
$469
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:20 pm -
1 stop22h 13m
Wed 10/212:33 pm -
1 stop10h 24m
Deal found 9/9![Copa Airlines logo]()
$493
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:01 am -
1 stop16h 00m
Thu 10/294:23 am -
1 stop20h 42m
Deal found 9/7![Copa Airlines logo]()
$500
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:20 pm -
1 stop26h 10m
Fri 10/96:30 pm -
1 stop19h 29m
Deal found 9/9![Copa Airlines logo]()
$516
This Cheapflightsfares deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:00 am -
1 stop8h 24m
Mon 10/261:30 pm -
1 stop10h 27m
Deal found 9/5![JetBlue logo]()
$531
This Booking.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Mon 10/124:14 am -
1 stop9h 45m
Deal found 9/7![Multiple Airlines logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Sun 10/182:33 pm -
1 stop23h 26m
Deal found 9/9![Multiple Airlines logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Wed 10/214:14 am -
1 stop9h 45m
Deal found 9/9![Multiple Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:26 am -
2 stops13h 11m
Thu 10/296:40 pm -
1 stop19h 06m
Deal found 9/8![Multiple Airlines logo]()
$576
This Faresmojo deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:00 am -
1 stop8h 29m
Sun 1/32:30 pm -
1 stop10h 19m
Deal found 9/7![JetBlue logo]()
$581
Best flights from Chicago to GuayaquilDiscover carefully curated flight deals from Chicago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Chicago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:13 pm -
1 stop20h 02m
Fri 11/62:47 pm -
1 stop22h 59m
Deal found 9/7![Copa Airlines logo]()
$469
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop8h 34m
Tue 12/12:30 pm -
1 stop9h 58m
Deal found 9/9![JetBlue logo]()
$615
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:54 am -
2 stops14h 22m
Tue 12/16:00 am -
2 stops15h 06m
Deal found 9/9![American Airlines logo]()
$649
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:55 am -
2 stops16h 42m
Fri 11/62:47 pm -
2 stops30h 27m
Deal found 9/7![United Airlines logo]()
$679
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:35 am -
1 stop12h 21m
Tue 12/12:45 pm -
1 stop23h 01m
Deal found 9/9![Copa Airlines logo]()
$469
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:01 am -
1 stop16h 00m
Thu 10/294:23 am -
1 stop20h 42m
Deal found 9/7![Copa Airlines logo]()
$500
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop8h 34m
Wed 12/22:30 pm -
1 stop9h 58m
Deal found 9/9![JetBlue logo]()
$615
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:20 pm -
1 stop26h 10m
Fri 10/96:30 pm -
1 stop19h 29m
Deal found 9/9![Copa Airlines logo]()
$516
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:05 pm -
1 stop19h 29m
Wed 11/116:00 am -
2 stops14h 56m
Deal found 9/8![American Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
2 stops17h 37m
Mon 10/268:23 am -
2 stops16h 22m
Deal found 9/5![United Airlines logo]()
$679
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:20 pm -
1 stop26h 10m
Wed 10/148:24 am -
1 stop16h 33m
Deal found 9/7![Copa Airlines logo]()
$516
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:50 am -
2 stops14h 36m
Wed 12/26:00 am -
1 stop14h 49m
Deal found 9/9![American Airlines logo]()
$686
Last-minute flights from Chicago to GuayaquilDiscover last-minute flight deals from Chicago to Guayaquil. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Guayaquil. Data last updated September 9, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:20 pm -
1 stop26h 10m
Fri 10/96:30 pm -
1 stop19h 29m
Deal found 9/9![Copa Airlines logo]()
$516
This Booking.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Mon 10/124:14 am -
1 stop9h 45m
Deal found 9/7![Multiple Airlines logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Sun 10/182:33 pm -
1 stop23h 26m
Deal found 9/9![Multiple Airlines logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Wed 10/214:14 am -
1 stop9h 45m
Deal found 9/9![Multiple Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Mon 10/194:14 am -
1 stop9h 45m
Deal found 9/9![Multiple Airlines logo]()
$599
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:20 pm -
1 stop22h 13m
Wed 10/212:33 pm -
1 stop10h 24m
Deal found 9/9![Copa Airlines logo]()
$493
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:44 pm -
2 stops39h 37m
Sat 10/172:33 pm -
1 stop10h 24m
Deal found 9/6![Multiple Airlines logo]()
$600
This Cheapflightsfares deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:00 am -
1 stop8h 24m
Mon 10/261:30 pm -
1 stop10h 27m
Deal found 9/5![JetBlue logo]()
$531
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:01 am -
1 stop26h 32m
Sun 11/14:22 am -
1 stop9h 24m
Deal found 9/7![Copa Airlines logo]()
$469
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:01 am -
1 stop16h 00m
Thu 10/294:23 am -
1 stop20h 42m
Deal found 9/7![Copa Airlines logo]()
$500
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:26 am -
2 stops13h 11m
Thu 10/296:40 pm -
1 stop19h 06m
Deal found 9/8![Multiple Airlines logo]()
$576
One-way flights from Chicago to GuayaquilSearch for one-way flight options from Chicago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Chicago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:20 pm -
1 stop8h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Copa Airlines logo]()
$203
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:35 am -
1 stop12h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Copa Airlines logo]()
$212
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:20 am -
2 stops12h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$215
This eDestinos deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop20h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Arajet logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:20 pm -
1 stop8h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Copa Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop8h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Copa Airlines logo]()
$233
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:20 pm -
1 stop20h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Copa Airlines logo]()
$236
This TravelUp deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:20 am -
1 stop21h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Arajet logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
3 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
2 stops17h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:44 pm -
3 stops41h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$270
Find flight deals from Chicago to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $453 (Kiwi.com) |
One-way from | $203 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $530 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Chicago to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Mon 10/19
3:20 pm-10:33 am
1 stop19h 13m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$212
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Wed 10/7
3:20 pm-11:21 am
1 stop20h 01m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$236
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Fri 12/4
5:45 am-1:12 am
1 stop18h 27m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$278
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Mon 10/5
5:30 am-2:15 am
1 stop20h 45m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$313
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Tue 10/13
7:30 am-11:37 pm
2 stops16h 07m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$315
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Thu 10/1
7:30 am-11:37 pm
2 stops16h 07m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$315
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Fri 10/2
5:30 am-11:37 pm
2 stops18h 07m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$315
Quickest round-trip
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Thu 10/1
8:01 am-11:37 pm
1 stop15h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$338
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Fri 10/30
3:13 pm-11:15 am
1 stop20h 02m
Guayaquil Jose Joaquin de Olmedo
Fri 11/6
2:47 pm-12:46 pm
1 stop22h 59m
$469
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Wed 11/18
7:35 am-8:56 pm
1 stop12h 21m
Guayaquil Jose Joaquin de Olmedo
Tue 12/1
2:45 pm-12:46 pm
1 stop23h 01m
$469
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Chicago to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Chicago with our price prediction graph.
CHI-GYE
ORD-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Guayaquil
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What is the cheapest month to book a flight from Chicago to Guayaquil?
Currently, January is the cheapest month in which you can book a flight from Chicago to Guayaquil (average of $411). Flying from Chicago to Guayaquil in December is currently the most expensive (average of $659). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Guayaquil?
Airfare is typical for this route at the moment.
Chicago to Guayaquil flights typically cost between $435 and $530 in November.The cheapest round-trip price found within the last 5 days was $453 on Copa Airlines (Nov 15-Nov 22).
What’s the top layover airport for flights from Chicago to Guayaquil?
Share of 1-stop round-trip flights from Chicago to Guayaquil chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 72% of 1-stop itineraries from Chicago to Guayaquil on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Guayaquil?
Average round-trip fare for 1-stop flights from Chicago to Guayaquil, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $413.
What’s the fastest layover option from Chicago to Guayaquil?
Shortest average travel time for 1-stop one-way flights from Chicago to Guayaquil, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 8h 41m.
Which airport typically offers the quickest layover for flights from Chicago to Guayaquil?
Average layover duration for 1-stop one-way flights from Chicago to Guayaquil, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 50m.
How far ahead should I book a flight from Chicago to Guayaquil?
To ensure you get the cheapest price possible for a flight from Chicago to Guayaquil, you should look to book at least 17 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 9, 2026.
Get a feel of what it's like to fly with Copa Airlines,American Airlines, andJetBlue from Chicago to Guayaquil by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Chicago and Guayaquil flights
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Top 5 airlines flying from Chicago to Guayaquil
Discover the top 5 airlines that operate flights from Chicago to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$532 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$352 | Average$573 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$369 | Average$540 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$382 | Average$666 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$387 | Average$777 | FlexibilityNo cancel fee | On-time71% |