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Guatemala

$319+ Cheap flights from Des Moines (DSM) to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala

Keep the following information in mind while searching for Des Moines to Guatemala flight deals. Data was last updated August 14, 2025.

Round-trip from

$453
(Avianca)

One-way from

$319
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$597
From Des Moines to Guatemala
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One-way flight from Des Moines to Guatemala
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Highest demand for flights based on searches. 16% potential increase in price ($160 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($57 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Des Moines to Guatemala

Cheapest flights from Des Moines to Guatemala
Explore the most affordable flight options available from Des Moines to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:56 pmDSM - GUA
1 stop9h 59mMultiple Airlines
Thu 1/151:22 pmGUA - DSM
1 stop9h 24mMultiple Airlines
Deal found 8/11$437
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:15 amDSM - GUA
2 stops17h 55mMultiple Airlines
Tue 9/235:20 amGUA - DSM
2 stops16h 08mMultiple Airlines
Deal found 8/14$453
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:44 amDSM - GUA
1 stop6h 46mDelta
Mon 10/612:56 pmGUA - DSM
1 stop8h 34mDelta
Deal found 8/12$466
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - GUA
1 stop9h 59mMultiple Airlines
Thu 1/151:22 pmGUA - DSM
1 stop9h 24mMultiple Airlines
Deal found 8/11$475
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:11 amDSM - GUA
1 stop13h 03mAmerican Airlines
Mon 10/68:29 amGUA - DSM
1 stop9h 17mAmerican Airlines
Deal found 8/13$483
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:00 amDSM - GUA
2 stops28h 26mMultiple Airlines
Thu 1/151:22 pmGUA - DSM
1 stop9h 24mMultiple Airlines
Deal found 8/11$494
This Avianca deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:00 amDSM - GUA
1 stop11h 10mAvianca
Fri 1/168:40 amGUA - DSM
1 stop12h 56mAvianca
Deal found 8/11$496
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/23:39 pmDSM - GUA
1 stop7h 04mAmerican Airlines
Sun 11/91:48 pmGUA - DSM
1 stop9h 28mAmerican Airlines
Deal found 8/12$505
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:10 amDSM - GUA
1 stop13h 04mAmerican Airlines
Fri 10/38:30 amGUA - DSM
1 stop8h 05mAmerican Airlines
Deal found 8/12$506

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala that are best for you.

Fly from

Des Moines

Fly to

Guatemala

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 12/7

2:56 pm-12:55 am

1 stop9h 59m

Guatemala City La Aurora

Thu 1/15

1:22 pm-10:46 pm

1 stop9h 24m

$437

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 9/17

6:15 am-11:10 pm

2 stops17h 55m

Guatemala City La Aurora

Tue 9/23

5:20 am-10:28 pm

2 stops16h 08m

$453

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 10/2

5:44 am-11:30 am

1 stop6h 46m

Guatemala City La Aurora

Mon 10/6

12:56 pm-10:30 pm

1 stop8h 34m

$466

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 12/8

9:31 am-12:26 pm

2 stops26h 55m

Guatemala City La Aurora

Thu 1/15

1:22 pm-10:46 pm

1 stop9h 24m

$470

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 12/4

2:56 pm-12:55 am

1 stop9h 59m

Guatemala City La Aurora

Wed 1/14

1:59 am-10:46 pm

1 stop20h 47m

$475

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 10/2

5:11 am-5:14 pm

1 stop13h 03m

Guatemala City La Aurora

Mon 10/6

8:29 am-6:46 pm

1 stop9h 17m

$483

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 9/28

7:17 am-5:14 pm

2 stops10h 57m

$319

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 9/27

8:00 am-7:12 pm

2 stops12h 12m

$319

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 9/28

5:44 am-11:30 am

1 stop6h 46m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Des Moines to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala

What is the cheapest month to book a flight from Des Moines to Guatemala?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $291). Flying from Des Moines to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GT?

Find hourly flight availability from Des Moines to Guatemala. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Guatemala as you normally would.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated August 14, 2025.
See what other customers who have flown with United Airlines and American Airlines from Des Moines to Guatemala have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,916 reviews

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,916 reviews
United Airlines
7.4
Good
8,916 reviews

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,916 reviews

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Guatemala?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to Guatemala. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • Can I find deals for flights from Des Moines to Guatemala that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala.

  • Can I find deals for business class flights from Des Moines to Guatemala?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $291). Flying from Des Moines to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
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Moline to San Salvador flights
La Crosse to Panama City flights
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Des Moines to Tegucigalpa flights

Top 2 airlines flying from Des Moines to Guatemala

Discover the top 2 airlines that operate flights from Des Moines to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$493Average$778FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$493Average$762FlexibilityNo cancel feeOn-time71%

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