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$203+ Cheap flights from Des Moines (DSM) to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Des Moines to Guatemala

Cheapest flights from Des Moines to Guatemala
Explore the most affordable flight options available from Des Moines to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:56 pmDSM - GUA
1 stop21h 28mMultiple Airlines
Tue 1/137:45 pmGUA - DSM
2 stops43h 55mMultiple Airlines
Deal found 11/13$432
This Mytrip deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/171:37 pmDSM - GUA
2 stops21h 44mMultiple Airlines
Mon 11/2411:10 amGUA - DSM
3 stops36h 14mMultiple Airlines
Deal found 11/10$464
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:28 pmDSM - GUA
2 stops17h 55mMultiple Airlines
Sun 12/141:39 pmGUA - DSM
1 stop8h 42mMultiple Airlines
Deal found 11/12$465
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:30 pmDSM - GUA
1 stop17h 49mMultiple Airlines
Mon 11/242:40 pmGUA - DSM
2 stops28h 21mMultiple Airlines
Deal found 11/12$504
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:34 amDSM - GUA
3 stops25h 45mMultiple Airlines
Tue 11/251:38 pmGUA - DSM
1 stop9h 46mMultiple Airlines
Deal found 11/12$518

Cheap flight deals from Des Moines to Guatemala

Keep the following information in mind while searching for Des Moines to Guatemala flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$432
(Kiwi.com)

One-way from

$203
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$871
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
Search Deals
From Des Moines to Guatemala
Search Deals
One-way flight from Des Moines to Guatemala
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($157 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala that are best for you.

Fly from

Des Moines

Fly to

Guatemala

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 2/4

7:40 am-11:29 pm

2 stops15h 49m

Guatemala City La Aurora

Wed 2/25

7:00 am-10:26 pm

2 stops15h 26m

$533

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 12/12

7:28 pm-7:41 am

3 stops36h 13m

Guatemala City La Aurora

Sun 12/14

2:38 pm-2:58 pm

3 stops24h 20m

$542

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/19

4:00 pm-2:07 pm

1 stop22h 07m

Guatemala City La Aurora

Mon 1/26

3:12 pm-11:23 pm

1 stop8h 11m

$552

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 2/4

3:35 pm-12:26 pm

2 stops20h 51m

Guatemala City La Aurora

Tue 2/24

2:10 am-9:51 pm

2 stops19h 41m

$636

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/19

6:48 pm-12:26 pm

2 stops17h 38m

Guatemala City La Aurora

Sun 1/25

2:10 am-5:47 pm

2 stops15h 37m

$636

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 3/9

5:52 pm-10:55 am

2 stops18h 03m

Guatemala City La Aurora

Fri 3/13

3:15 pm-12:05 pm

2 stops19h 50m

$661

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 12/3

8:00 am-9:25 pm

2 stops13h 25m

Guatemala City La Aurora

Wed 12/17

1:28 pm-9:37 pm

1 stop8h 09m

$699

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 12/11

8:15 am-7:39 pm

1 stop11h 24m

Guatemala City La Aurora

Tue 1/13

7:00 am-10:30 pm

1 stop15h 30m

$705

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 3/9

7:15 am-4:25 pm

1 stop10h 10m

Guatemala City La Aurora

Fri 3/13

6:00 am-10:36 pm

1 stop15h 36m

$714

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/19

2:08 pm-12:24 pm

3 stops46h 16m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 15 results
1
2

Best time to book a flight from Des Moines to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala

What is the cheapest month to book a flight from Des Moines to Guatemala?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $292). Flying from Des Moines to Guatemala in March is currently the most expensive (average of $740). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GT?

Find hourly flight availability from Des Moines to Guatemala. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 40% on flights from Des Moines to Guatemala by exploring options for tickets in the afternoon.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated November 13, 2025.
See what other customers who have flown with United Airlines and American Airlines from Des Moines to Guatemala have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,017 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,017 reviews
United Airlines
7.4
Good
9,017 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,051 reviews
United Airlines
7.4
Good
9,017 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Guatemala?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to Guatemala. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • How long is the flight from Des Moines to Guatemala?

    There are many flights that can get you from Des Moines to Guatemala in 15h 49m. Fly via American Airlines or United Airlines to get the fastest option. There are 1871 mi between Des Moines and Guatemala. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Des Moines to Guatemala that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala.

  • Can I find deals for business class flights from Des Moines to Guatemala?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $292). Flying from Des Moines to Guatemala in March is currently the most expensive (average of $740). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
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Omaha to Managua flights
Cedar Rapids to Guatemala City flights
Cedar Rapids to San Salvador flights
Cedar Rapids to Philip S.W.Goldson flights
Cedar Rapids to Liberia flights
Moline to San José flights
Cedar Rapids to Panama City flights
Des Moines to Managua flights
Omaha to San Pedro Sula flights
Moline to Philip S.W.Goldson flights
Moline to San Salvador flights
Moline to Liberia flights
Moline to Guatemala City flights
La Crosse to Panama City flights
Cedar Rapids to Coxen Hole flights
Des Moines to Tegucigalpa flights

Top 2 airlines flying from Des Moines to Guatemala

Discover the top 2 airlines that operate flights from Des Moines to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$488Average$713FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$493Average$793FlexibilityNo cancel feeOn-time69%

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