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$147+ Cheap flights from Des Moines (DSM) to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Oct 29 — Nov 51
Wed 10/29
Wed 11/5
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala

Keep the following information in mind while searching for Des Moines to Guatemala flight deals. Data was last updated September 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$422
(Kiwi.com)

One-way from

$192
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$806
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
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From Des Moines to Guatemala
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One-way flight from Des Moines to Guatemala
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Highest demand for flights based on searches. 16% potential increase in price ($160 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($57 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Guatemala

Cheapest flights from Des Moines to Guatemala
Explore the most affordable flight options available from Des Moines to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:50 amDSM - GUA
1 stop25h 36mMultiple Airlines
Thu 11/208:25 amGUA - DSM
2 stops28h 30mMultiple Airlines
Deal found 9/29$365
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:51 amDSM - GUA
1 stop25h 31mMultiple Airlines
Fri 10/1712:27 pmGUA - DSM
2 stops19h 02mMultiple Airlines
Deal found 9/28$422
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/108:55 amDSM - GUA
2 stops27h 27mMultiple Airlines
Thu 10/1611:25 amGUA - DSM
1 stop20h 05mMultiple Airlines
Deal found 9/28$424

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala that are best for you.

Fly from

Des Moines

Fly to

Guatemala

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 2/6

7:38 am-9:05 pm

2 stops13h 27m

Guatemala City La Aurora

Tue 2/10

7:00 am-11:20 pm

2 stops16h 20m

$464

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 11/13

10:50 am-9:38 pm

3 stops34h 48m

Guatemala City La Aurora

Thu 11/20

1:38 pm-12:55 pm

2 stops23h 17m

$468

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 2/6

8:00 am-10:48 pm

2 stops14h 48m

Guatemala City La Aurora

Mon 2/9

2:10 am-2:22 pm

1 stop12h 12m

$481

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/12

5:51 pm-2:51 pm

2 stops21h 00m

Guatemala City La Aurora

Sat 1/17

4:02 pm-10:50 am

2 stops18h 48m

$481

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 1/17

7:50 am-9:25 pm

2 stops13h 35m

Guatemala City La Aurora

Sat 1/24

2:10 am-2:33 pm

2 stops12h 23m

$498

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 11/12

6:00 am-8:16 pm

1 stop14h 16m

Guatemala City La Aurora

Wed 11/19

7:00 am-10:02 pm

2 stops15h 02m

$498

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 11/11

6:49 am-8:16 pm

2 stops13h 27m

Guatemala City La Aurora

Tue 11/18

7:00 am-10:59 pm

2 stops15h 59m

$510

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 12/4

2:56 pm-12:55 am

1 stop9h 59m

$147

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 10/19

8:47 pm-11:31 am

3 stops39h 44m

$192

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 12/11

11:29 am-10:39 pm

1 stop11h 10m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/29

Showing 1-10 of 12 results
1
2

Best time to book a flight from Des Moines to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala

What is the cheapest month to book a flight from Des Moines to Guatemala?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $291). Flying from Des Moines to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GT?

Find hourly flight availability from Des Moines to Guatemala. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Guatemala as you normally would.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated September 29, 2025.
See what other customers who have flown with United Airlines and American Airlines from Des Moines to Guatemala have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,924 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Guatemala?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to Guatemala. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • How long is the flight from Des Moines to Guatemala?

    There are many flights that can get you from Des Moines to Guatemala in 13h 27m. Fly via American Airlines to get the fastest option. There are 1871 mi between Des Moines and Guatemala.

  • Can I find deals for flights from Des Moines to Guatemala that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala.

  • Can I find deals for business class flights from Des Moines to Guatemala?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $291). Flying from Des Moines to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
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Des Moines to San José flights
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Omaha to Managua flights
Cedar Rapids to Philip S.W.Goldson flights
Cedar Rapids to Panama City flights
Moline to San Salvador flights
Omaha to San Pedro Sula flights
Moline to Philip S.W.Goldson flights
Moline to Guatemala City flights
Des Moines to Managua flights
Moline to Liberia flights
Moline to San José flights
Cedar Rapids to Coxen Hole flights
La Crosse to Panama City flights
Des Moines to Tegucigalpa flights

Top 2 airlines flying from Des Moines to Guatemala

Discover the top 2 airlines that operate flights from Des Moines to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$488Average$759FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$493Average$718FlexibilityNo cancel feeOn-time69%

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