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$167+ Cheap flights from Des Moines (DSM) to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala

Cheapest flights from Des Moines to Guatemala
Explore the most affordable flight options available from Des Moines to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:31 amDSM - GUA
2 stops27h 03mMultiple Airlines
Sat 1/31:39 pmGUA - DSM
1 stop28h 01mMultiple Airlines
Deal found 12/27$1,168
This Gurufare deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:26 pmDSM - GUA
2 stops18h 24mGOL
Sat 1/34:08 pmGUA - DSM
2 stops18h 39mGOL
Deal found 12/27$1,207
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/273:14 pmDSM - GUA
2 stops31h 46mUnited Airlines
Wed 12/315:06 pmGUA - DSM
2 stops21h 27mUnited Airlines
Deal found 12/26$1,313
This Gurufare deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/273:28 pmDSM - GUA
1 stop8h 28mGOL
Wed 12/316:39 amGUA - DSM
1 stop10h 22mGOL
Deal found 12/26$1,498

Find flight deals from Des Moines to Guatemala

Keep the following information in mind while searching for Des Moines to Guatemala flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$412
(Kiwi.com)

One-way from

$167
(Avianca)

Popular in

March

Cheapest in

February

Average price

$778
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
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From Des Moines to Guatemala
Search Deals
One-way flight from Des Moines to Guatemala
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($108 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($64 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala that are best for you.

Fly from

Des Moines

Fly to

Guatemala

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 1/25

2:58 pm-12:29 pm

1 stop21h 31m

Guatemala City La Aurora

Sun 2/1

1:28 pm-10:19 am

2 stops20h 51m

$412

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 2/2

11:09 am-12:29 pm

2 stops25h 20m

Guatemala City La Aurora

Sun 2/8

12:15 pm-10:19 am

3 stops22h 04m

$435

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 2/10

11:35 am-2:07 pm

1 stop26h 32m

Guatemala City La Aurora

Tue 2/17

2:53 pm-10:47 am

1 stop19h 54m

$570

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 2/4

5:05 am-11:29 pm

1 stop18h 24m

Guatemala City La Aurora

Wed 2/25

2:53 pm-11:38 pm

1 stop8h 45m

$581

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 1/28

8:00 am-7:10 pm

1 stop11h 10m

$199

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/26

8:30 am-6:19 am

3 stops45h 49m

$215

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 2/10

5:01 pm-1:13 pm

2 stops20h 12m

$299

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 2/10

5:35 am-12:45 pm

1 stop7h 10m

$303

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/26

5:51 pm-1:13 pm

2 stops19h 22m

$309

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 1/28

7:00 am-11:29 pm

2 stops16h 29m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Best time to book a flight from Des Moines to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala

What is the cheapest month to book a flight from Des Moines to Guatemala?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $291). Flying from Des Moines to Guatemala in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated December 28, 2025.
See what other customers who have flown with United Airlines and American Airlines from Des Moines to Guatemala have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,113 reviews

Food

6.6

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,113 reviews
United Airlines
7.4
Good
9,113 reviews

Food

6.6

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,073 reviews
United Airlines
7.4
Good
9,113 reviews

Food

6.6

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Guatemala?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to Guatemala. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • Can I find deals for flights from Des Moines to Guatemala that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala.

  • Can I find deals for business class flights from Des Moines to Guatemala?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala (average of $291). Flying from Des Moines to Guatemala in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Guatemala

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Top 2 airlines flying from Des Moines to Guatemala

Discover the top 2 airlines that operate flights from Des Moines to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$468Average$724FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$494Average$722FlexibilityNo cancel feeOn-time69%

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