HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guatemala City

$123+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Guatemala City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$280
(Mytrip)

One-way from

$123
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$715
From Des Moines to Guatemala City La Aurora
Search Deals
One-way flight from Des Moines to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($151 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($57 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/186:30 amDSM - GUA
1 stop18h 34mMultiple Airlines
Thu 7/2412:59 amGUA - DSM
1 stop11h 50mMultiple Airlines
Deal found 6/11$280
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/265:12 amDSM - GUA
1 stop13h 08mAmerican Airlines
Tue 9/168:30 amGUA - DSM
1 stop8h 05mAmerican Airlines
Deal found 6/10$463
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/266:15 amDSM - GUA
1 stop6h 21mUnited Airlines
Mon 9/151:30 amGUA - DSM
1 stop11h 47mUnited Airlines
Deal found 6/10$556

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Des Moines

Fly to

Guatemala City

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 7/18

6:30 am-12:04 am

1 stop18h 34m

Guatemala City La Aurora

Thu 7/24

12:59 am-1:49 pm

1 stop11h 50m

$280

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 8/26

5:12 am-5:20 pm

1 stop13h 08m

Guatemala City La Aurora

Tue 9/16

8:30 am-5:35 pm

1 stop8h 05m

$463

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 8/26

6:15 am-11:36 am

1 stop6h 21m

Guatemala City La Aurora

Mon 9/15

1:30 am-2:17 pm

1 stop11h 47m

$556

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 7/25

6:30 am-12:04 am

1 stop18h 34m

$123

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 7/26

8:00 am-10:35 pm

2 stops15h 35m

$277

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 8/16

5:44 am-11:30 am

1 stop6h 46m

$323

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 7/26

6:25 am-7:50 pm

1 stop14h 25m

$368

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 6/23

6:07 am-4:32 pm

1 stop11h 25m

$586

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GUA?

Find hourly flight availability from Des Moines to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 8% on flights from Des Moines to Guatemala City by exploring options for tickets in the afternoon.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated June 12, 2025.
To help decide which airline to fly from Des Moines to Guatemala City, see what other customers have to say about Delta, Copa Airlines and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $463, American Airlines will fly you from Des Moines to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $556. American Airlines is currently priced 42% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Guatemala City one-way?

    One-way options have recently been found by users for as low as $277 on Copa Airlines. Other airlines that offer cheap prices include Delta from $323 and American Airlines from $368 one-way.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Panajachel
Antigua

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Guatemala City flights
Cedar Rapids to Guatemala City flights
Moline to Guatemala City flights

Top 3 airlines flying from Des Moines to Guatemala City

Discover the top 3 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$456Average$564FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$532Average$778FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$550Average$715FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.