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$191+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$390
(Kiwi.com)

One-way from

$191
(Avianca)

Popular in

March

Cheapest in

February

Average price

$713
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
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From Des Moines to Guatemala City La Aurora
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One-way flight from Des Moines to Guatemala City La Aurora
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Highest demand for flights based on searches. 13% potential increase in price ($114 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/222:58 pmDSM - GUA
1 stop21h 31mMultiple Airlines
Sun 2/11:28 pmGUA - DSM
2 stops20h 51mMultiple Airlines
Deal found 1/6$390
This Avianca deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/258:10 amDSM - GUA
2 stops9h 55mMultiple Airlines
Sun 2/15:10 amGUA - DSM
2 stops17h 20mMultiple Airlines
Deal found 1/7$405
This Avianca deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/38:10 amDSM - GUA
2 stops15h 00mMultiple Airlines
Tue 2/175:10 amGUA - DSM
2 stops17h 10mMultiple Airlines
Deal found 1/7$414
This Avianca deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/38:10 amDSM - GUA
2 stops10h 25mMultiple Airlines
Tue 2/245:10 amGUA - DSM
2 stops17h 10mMultiple Airlines
Deal found 1/6$455
This Avianca deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/288:10 amDSM - GUA
2 stops15h 00mMultiple Airlines
Sun 2/85:10 amGUA - DSM
2 stops17h 20mMultiple Airlines
Deal found 1/7$463
This Avianca deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/258:00 amDSM - GUA
1 stop11h 10mAvianca
Thu 1/295:10 amGUA - DSM
2 stops16h 40mAvianca
Deal found 1/5$472
This Avianca deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/158:00 amDSM - GUA
2 stops15h 10mMultiple Airlines
Thu 1/229:55 amGUA - DSM
2 stops12h 35mMultiple Airlines
Deal found 1/7$475
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:32 pmDSM - GUA
2 stops15h 48mMultiple Airlines
Thu 2/261:28 pmGUA - DSM
1 stop9h 38mMultiple Airlines
Deal found 1/7$483

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Des Moines

Fly to

Guatemala City

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 2/18

7:52 am-11:10 pm

2 stops15h 18m

Guatemala City La Aurora

Wed 2/25

5:10 am-10:20 pm

2 stops17h 10m

$405

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 2/1

8:10 am-11:10 pm

2 stops15h 00m

Guatemala City La Aurora

Mon 2/9

5:10 am-10:30 pm

2 stops17h 20m

$405

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 2/11

8:10 am-6:35 pm

2 stops10h 25m

Guatemala City La Aurora

Wed 3/4

5:10 am-10:20 pm

2 stops17h 10m

$405

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 1/25

8:00 am-7:10 pm

1 stop11h 10m

Guatemala City La Aurora

Sun 2/1

5:10 am-10:30 pm

2 stops17h 20m

$408

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 2/3

8:10 am-11:10 pm

2 stops15h 00m

Guatemala City La Aurora

Tue 2/17

5:10 am-10:20 pm

2 stops17h 10m

$414

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 3/4

7:52 am-6:35 pm

2 stops10h 43m

Guatemala City La Aurora

Tue 3/24

5:10 am-10:44 pm

2 stops16h 34m

$414

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 1/22

2:58 pm-12:29 pm

1 stop21h 31m

Guatemala City La Aurora

Sun 2/1

1:28 pm-10:46 pm

1 stop9h 18m

$428

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 2/3

8:10 am-6:35 pm

2 stops10h 25m

Guatemala City La Aurora

Tue 2/24

5:10 am-10:20 pm

2 stops17h 10m

$455

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 1/28

8:00 am-7:10 pm

1 stop11h 10m

Guatemala City La Aurora

Sun 2/8

5:10 am-10:30 pm

2 stops17h 20m

$466

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 1/25

8:00 am-7:10 pm

1 stop11h 10m

Guatemala City La Aurora

Thu 1/29

5:10 am-9:50 pm

2 stops16h 40m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 16 results
1
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Compare providers for flights from Des Moines to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated January 8, 2026.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
United Airlines
7.4
Good
9,139 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
American Airlines
7.2
Good
11,095 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $468, American Airlines will fly you from Des Moines to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $494. American Airlines is currently priced 35% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Des Moines to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Guatemala City

Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$468Average$690FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$494Average$722FlexibilityNo cancel feeOn-time69%

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