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$299+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
ago. 23 — ago. 301
sáb. 8/23
sáb. 8/30
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 18, 2025.

Round-trip from

$341
(Kiwi.com)

One-way from

$299
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$597
From Des Moines to Guatemala City La Aurora
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One-way flight from Des Moines to Guatemala City La Aurora
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Highest demand for flights based on searches. 16% potential increase in price ($160 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($57 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/210:41 amDSM - GUA
1 stop25h 44mMultiple Airlines
jue. 10/912:27 pmGUA - DSM
2 stops27h 47mMultiple Airlines
Deal found 8/18$341
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/308:00 amDSM - GUA
2 stops12h 12mAmerican Airlines
mar. 10/78:29 amGUA - DSM
2 stops10h 42mAmerican Airlines
Deal found 8/16$496
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/23:39 pmDSM - GUA
1 stop7h 04mAmerican Airlines
dom. 11/97:00 amGUA - DSM
1 stop16h 16mAmerican Airlines
Deal found 8/17$505
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/25:11 amDSM - GUA
1 stop13h 03mAmerican Airlines
jue. 10/98:29 amGUA - DSM
1 stop9h 17mAmerican Airlines
Deal found 8/18$507

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Des Moines

Fly to

Guatemala City

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

jue. 10/2

10:41 am-11:25 am

1 stop25h 44m

Guatemala City La Aurora

jue. 10/9

12:27 pm-5:14 pm

2 stops27h 47m

$341

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

mié. 1/28

5:01 am-9:55 pm

1 stop16h 54m

Guatemala City La Aurora

jue. 2/5

7:19 am-10:40 pm

1 stop15h 21m

$460

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

mar. 9/30

8:00 am-7:12 pm

2 stops12h 12m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GUA?

Find hourly flight availability from Des Moines to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 8% on flights from Des Moines to Guatemala City by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Des Moines to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated agosto 18, 2025.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,925 reviews

Food

6.6

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,925 reviews
United Airlines
7.4
Good
8,925 reviews

Food

6.6

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,925 reviews

Food

6.6

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $493, American Airlines will fly you from Des Moines to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $493. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Panajachel
Antigua

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Alternative routes for Des Moines to Guatemala City

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Top 2 airlines flying from Des Moines to Guatemala City

Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$493Average$778FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$493Average$762FlexibilityNo cancel feeOn-time71%

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