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Guatemala City

$324+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Mar 29 — Apr 51
Sun 3/29
Sun 4/5
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:36 pm
DSM
-
GUA
2 stops20h 37m
Multiple Airlines
Sat 5/912:15 pm
GUA
-
DSM
1 stop26h 00m
Multiple Airlines
Deal found 2/23$406
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:36 pm
DSM
-
GUA
1 stop21h 44m
Multiple Airlines
Sat 5/912:15 pm
GUA
-
DSM
1 stop26h 00m
Multiple Airlines
Deal found 2/23$434
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:30 am
DSM
-
GUA
2 stops25h 50m
Multiple Airlines
Wed 5/1312:15 pm
GUA
-
DSM
1 stop26h 00m
Multiple Airlines
Deal found 2/23$460
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
DSM
-
GUA
2 stops38h 50m
Multiple Airlines
Sat 5/912:15 pm
GUA
-
DSM
1 stop26h 00m
Multiple Airlines
Deal found 2/23$471
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:33 pm
DSM
-
GUA
2 stops17h 47m
Multiple Airlines
Sat 5/912:15 pm
GUA
-
DSM
1 stop26h 00m
Multiple Airlines
Deal found 2/23$493
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:00 am
DSM
-
GUA
2 stops12h 32m
United Airlines
Tue 11/101:28 pm
GUA
-
DSM
1 stop9h 02m
United Airlines
Deal found 2/24$566
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:20 am
DSM
-
GUA
1 stop7h 10m
United Airlines
Wed 5/1312:27 pm
GUA
-
DSM
1 stop9h 18m
United Airlines
Deal found 2/23$573
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:15 am
DSM
-
GUA
1 stop7h 15m
United Airlines
Mon 5/1110:50 pm
GUA
-
DSM
2 stops14h 34m
United Airlines
Deal found 2/26$577

Find flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$406
(Kiwi.com)

One-way from

$324
(American Airlines)

Popular in

December

Cheapest in

February

Average price

$468
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
Search Deals
From Des Moines to Guatemala City La Aurora
Search Deals
One-way flight from Des Moines to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 4/22

8:20 am-2:30 pm

1 stop7h 10m

Guatemala City La Aurora

Wed 5/13

12:27 pm-10:45 pm

1 stop9h 18m

$573

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 4/24

8:03 pm-2:02 pm

2 stops18h 59m

Guatemala City La Aurora

Wed 4/29

3:14 pm-10:26 am

2 stops18h 12m

$603

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 5/2

8:15 am-2:30 pm

1 stop7h 15m

Guatemala City La Aurora

Sat 5/9

1:50 pm-10:45 pm

1 stop7h 55m

$613

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 7/8

6:20 am-11:24 am

1 stop6h 04m

Guatemala City La Aurora

Sun 7/12

6:15 am-10:35 pm

1 stop15h 20m

$616

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 4/29

4:23 pm-11:46 am

2 stops20h 23m

Guatemala City La Aurora

Sat 5/9

12:56 pm-10:32 pm

1 stop8h 36m

$639

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 5/5

5:45 am-11:46 am

1 stop7h 01m

Guatemala City La Aurora

Sat 5/9

12:56 pm-10:32 pm

1 stop8h 36m

$648

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 4/13

8:20 am-6:30 pm

2 stops11h 10m

Guatemala City La Aurora

Mon 4/20

5:25 am-10:43 pm

2 stops16h 18m

$658

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 4/11

8:20 am-4:37 pm

1 stop9h 17m

Guatemala City La Aurora

Sat 4/18

11:55 pm-12:29 pm

2 stops11h 34m

$664

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 7/6

5:00 am-4:37 pm

2 stops12h 37m

Guatemala City La Aurora

Mon 7/13

11:55 pm-12:30 pm

2 stops11h 35m

$690

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 8/22

6:15 am-12:45 pm

1 stop7h 30m

Guatemala City La Aurora

Tue 8/25

1:30 am-2:20 pm

1 stop11h 50m

$703

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/24

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $288). Flying from Des Moines to Guatemala City in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated February 27, 2026.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,349 reviews

Overall

7.4

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,349 reviews
United Airlines
7.4
Good
9,349 reviews

Overall

7.4

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,357 reviews
United Airlines
7.4
Good
9,349 reviews

Overall

7.4

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Guatemala City?

    Airlines like United Airlines, American Airlines, and Delta fly from Des Moines to Guatemala City in about 7h 10m. The time it takes to get you to your destination can typically vary by up to 13h 13m. The distance between Des Moines and Guatemala City is about 1871 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $468, American Airlines will fly you from Des Moines to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $494. American Airlines is currently priced 28% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Guatemala City one-way?

    One-way options have recently been found by users for as low as $242 on Avianca. Other airlines that offer cheap prices include United Airlines from $353 and American Airlines from $358 one-way.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $288). Flying from Des Moines to Guatemala City in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Des Moines to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Guatemala City flights

Top 2 airlines flying from Des Moines to Guatemala City

Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$468Average$728FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$494Average$718FlexibilityNo cancel feeOn-time69%

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