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$348+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$448
(Kiwi.com)

One-way from

$348
(Mytrip)

Popular in

March

Cheapest in

September

Average price

$650
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
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From Des Moines to Guatemala City La Aurora
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One-way flight from Des Moines to Guatemala City La Aurora
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Highest demand for flights based on searches. 18% potential increase in price ($172 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($61 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/910:50 amDSM - GUA
1 stop25h 36mMultiple Airlines
Sun 11/162:55 pmGUA - DSM
2 stops24h 03mMultiple Airlines
Deal found 10/15$462
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3012:51 pmDSM - GUA
2 stops23h 42mMultiple Airlines
Sun 12/71:29 pmGUA - DSM
1 stop8h 52mMultiple Airlines
Deal found 10/16$583
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/303:31 pmDSM - GUA
1 stop7h 12mAmerican Airlines
Sun 12/71:40 pmGUA - DSM
2 stops10h 45mAmerican Airlines
Deal found 10/15$608
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:39 amDSM - GUA
2 stops27h 45mAmerican Airlines
Sat 12/1311:33 amGUA - DSM
1 stop11h 56mAmerican Airlines
Deal found 10/16$611

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Des Moines

Fly to

Guatemala City

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/5

10:53 am-2:03 pm

1 stop27h 10m

Guatemala City La Aurora

Fri 1/16

12:11 pm-5:08 pm

1 stop28h 57m

$466

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 1/5

10:53 am-2:03 pm

1 stop27h 10m

Guatemala City La Aurora

Sat 1/17

1:59 am-10:19 am

2 stops32h 20m

$556

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 11/30

12:51 pm-12:33 pm

2 stops23h 42m

Guatemala City La Aurora

Sun 12/7

1:29 pm-8:41 am

2 stops19h 12m

$593

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 11/30

11:30 am-10:43 pm

1 stop11h 13m

Guatemala City La Aurora

Sun 12/7

1:40 pm-12:25 am

2 stops10h 45m

$608

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 11/27

6:39 am-10:24 am

2 stops27h 45m

Guatemala City La Aurora

Sat 12/13

11:33 am-10:29 pm

2 stops10h 56m

$611

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 1/9

3:59 pm-11:17 pm

1 stop7h 18m

Guatemala City La Aurora

Sat 1/17

2:13 pm-11:29 pm

1 stop9h 16m

$649

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 10/19

8:47 pm-10:30 am

2 stops14h 43m

$348

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 10/19

5:47 am-11:31 am

1 stop6h 44m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Compare providers for flights from Des Moines to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $477). Flying from Des Moines to Guatemala City in November is currently the most expensive (average of $916). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GUA?

Find hourly flight availability from Des Moines to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 40% on flights from Des Moines to Guatemala City by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Des Moines to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated October 16, 2025.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
8,982 reviews
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
American Airlines
7.2
Good
11,043 reviews
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Guatemala City?

    Airlines like American Airlines fly from Des Moines to Guatemala City in about 11h 13m. The time it takes to get you to your destination can typically vary by up to . The distance between Des Moines and Guatemala City is about 1871 mi.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $488, American Airlines will fly you from Des Moines to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $493. American Airlines is currently priced 35% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $477). Flying from Des Moines to Guatemala City in November is currently the most expensive (average of $916). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

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Alternative routes for Des Moines to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Guatemala City

Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$488Average$725FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$493Average$715FlexibilityNo cancel feeOn-time69%

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