$308+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Guatemala City
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Best
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One-way
Cheapest flights from Des Moines to Guatemala CityExplore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This Avianca deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops13h 30m
Wed 10/145:25 am -
2 stops15h 50m
Deal found 8/23![Multiple Airlines logo]()
$626
This Avianca deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops18h 10m
Thu 10/155:25 am -
2 stops15h 50m
Deal found 8/24![Multiple Airlines logo]()
$705
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops18h 10m
Mon 10/125:25 am -
2 stops15h 50m
Deal found 8/25![Multiple Airlines logo]()
$712
This Avianca deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3011:32 am -
1 stop8h 28m
Sun 9/65:25 am -
2 stops13h 59m
Deal found 8/22![Multiple Airlines logo]()
$727
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
2 stops13h 30m
Fri 10/165:25 am -
2 stops15h 50m
Deal found 8/25![Multiple Airlines logo]()
$732
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 am -
2 stops17h 55m
Thu 9/245:25 am -
2 stops15h 50m
Deal found 8/25![Multiple Airlines logo]()
$737
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
2 stops18h 10m
Sat 10/1710:00 am -
2 stops11h 16m
Deal found 8/25![Multiple Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop7h 45m
Wed 10/146:15 am -
1 stop6h 59m
Deal found 8/23![United Airlines logo]()
$762
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops14h 23m
Thu 10/1512:04 pm -
1 stop20h 11m
Deal found 8/24![American Airlines logo]()
$769
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:14 am -
1 stop7h 51m
Wed 10/1412:04 pm -
1 stop10h 03m
Deal found 8/23![American Airlines logo]()
$770
This Avianca deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
2 stops18h 10m
Mon 10/55:25 am -
2 stops15h 50m
Deal found 8/26![Multiple Airlines logo]()
$774
Best flights from Des Moines to Guatemala CityDiscover carefully curated flight deals from Des Moines to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Des Moines to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This Avianca deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops13h 30m
Wed 10/145:25 am -
2 stops15h 50m
Deal found 8/23![Multiple Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops11h 37m
Wed 10/1412:26 pm -
1 stop7h 57m
Deal found 8/23![United Airlines logo]()
$762
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops14h 23m
Thu 10/1512:04 pm -
1 stop20h 11m
Deal found 8/24![American Airlines logo]()
$769
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:39 am -
1 stop6h 53m
Sat 10/172:12 pm -
1 stop7h 21m
Deal found 8/25![Delta logo]()
$930
This BusinessClass deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:17 pm -
2 stops20h 48m
Wed 12/301:16 am -
2 stops13h 40m
Deal found 8/23![GOL logo]()
$976
This Avianca deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops18h 10m
Thu 10/155:25 am -
2 stops15h 50m
Deal found 8/24![Multiple Airlines logo]()
$705
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops18h 10m
Mon 10/125:25 am -
2 stops15h 50m
Deal found 8/25![Multiple Airlines logo]()
$712
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
2 stops18h 10m
Sat 10/1710:00 am -
2 stops11h 16m
Deal found 8/25![Multiple Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop11h 37m
Mon 10/56:15 am -
1 stop15h 00m
Deal found 8/26![United Airlines logo]()
$953
Last-minute flights from Des Moines to Guatemala CityDiscover last-minute flight deals from Des Moines to Guatemala City. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Guatemala City. Data last updated August 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:33 am -
1 stop7h 49m
Sun 8/302:23 pm -
2 stops18h 37m
Deal found 8/25![American Airlines logo]()
$1,005
This BusinessClass deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:33 am -
1 stop7h 49m
Sun 8/3012:07 pm -
1 stop10h 00m
Deal found 8/25![GOL logo]()
$1,093
This Avianca deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3011:32 am -
1 stop8h 28m
Sun 9/65:25 am -
2 stops13h 59m
Deal found 8/22![Multiple Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:15 am -
1 stop11h 22m
Sun 9/612:27 pm -
1 stop6h 57m
Deal found 8/22![United Airlines logo]()
$981
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:10 pm -
2 stops18h 57m
Mon 9/72:23 pm -
2 stops18h 37m
Deal found 8/24![American Airlines logo]()
$1,006
This BusinessClass deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:33 am -
1 stop7h 49m
Fri 9/1111:46 am -
1 stop10h 26m
Deal found 8/25![GOL logo]()
$1,106
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 am -
2 stops17h 55m
Thu 9/245:25 am -
2 stops15h 50m
Deal found 8/25![Multiple Airlines logo]()
$737
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:30 am -
1 stop7h 50m
Thu 9/2411:46 am -
1 stop10h 26m
Deal found 8/25![American Airlines logo]()
$787
One-way flights from Des Moines to Guatemala CitySearch for one-way flight options from Des Moines to Guatemala City. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Des Moines to Guatemala City. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
2 stops13h 30m
Deal found 8/25![Multiple Airlines logo]()
$308
This Avianca deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops18h 10m
Deal found 8/23![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:58 pm -
3 stops20h 35m
Deal found 8/25![Multiple Airlines logo]()
$335
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
2 stops18h 10m
Deal found 8/25![Multiple Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am -
1 stop6h 47m
Deal found 8/25![Delta logo]()
$393
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:14 am -
1 stop7h 51m
Deal found 8/23![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:07 am -
2 stops15h 40m
Deal found 8/24![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop6h 24m
Deal found 8/26![United Airlines logo]()
$423
Find flight deals from Des Moines to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 26, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $626 (Avianca) |
One-way from | $308 (Avianca) |
Popular in | August |
Cheapest in | February |
Average price | $922 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 10/7
6:00 am-6:30 pm
2 stops13h 30m
Guatemala City La Aurora
Wed 10/14
5:25 am-10:15 pm
2 stops15h 50m
$626
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Thu 10/8
6:00 am-11:10 pm
2 stops18h 10m
Guatemala City La Aurora
Thu 10/15
5:25 am-10:15 pm
2 stops15h 50m
$705
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Thu 10/8
6:00 am-11:10 pm
2 stops18h 10m
Guatemala City La Aurora
Mon 10/12
5:25 am-10:15 pm
2 stops15h 50m
$712
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Sat 10/10
6:00 am-11:10 pm
2 stops18h 10m
Guatemala City La Aurora
Sat 10/17
10:00 am-10:16 pm
2 stops11h 16m
$755
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 10/7
6:00 am-4:37 pm
2 stops11h 37m
Guatemala City La Aurora
Wed 10/14
12:26 pm-9:23 pm
1 stop7h 57m
$762
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Thu 10/8
6:00 am-7:23 pm
2 stops14h 23m
Guatemala City La Aurora
Thu 10/15
12:04 pm-9:15 am
1 stop20h 11m
$769
Quickest round-trip
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Sat 10/10
5:39 am-11:32 am
1 stop6h 53m
Guatemala City La Aurora
Sat 10/17
2:12 pm-10:33 pm
1 stop7h 21m
$930
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Thu 10/1
6:00 am-4:37 pm
1 stop11h 37m
Guatemala City La Aurora
Mon 10/5
6:15 am-10:15 pm
1 stop15h 00m
$953
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Mon 12/21
6:17 pm-3:05 pm
2 stops20h 48m
Guatemala City La Aurora
Wed 12/30
1:16 am-2:56 pm
2 stops13h 40m
$976
Cheapest one-way
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 10/7
6:00 am-11:10 pm
2 stops18h 10m
$310
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
DSM-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated August 26, 2026.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Entertainment
7.1
Overall
7.4
Boarding
7.7
Comfort
7.3
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Food
6.7
Entertainment
7.1
Overall
7.4
Boarding
7.7
Comfort
7.3
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Food
6.7
Entertainment
7.1
Overall
7.4
Boarding
7.7
Comfort
7.3
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Des Moines and Guatemala City flights
Browse other Des Moines and Guatemala City flight options. Last updated on August 26, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Guatemala City
Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$468 | Average$692 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$519 | Average$722 | FlexibilityNo cancel fee | On-time69% |