$169+ Cheap flights from San Francisco to Greenville (SFO - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Greenville
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Cheapest flights from San Francisco to GreenvilleExplore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:12 am -
1 stop9h 47m
Sat 10/31:36 pm -
1 stop7h 32m
Deal found 8/31![American Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:59 pm -
1 stop10h 00m
Wed 9/3011:04 am -
1 stop10h 05m
Deal found 9/2![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:40 pm -
1 stop8h 32m
Thu 12/177:25 pm -
1 stop7h 40m
Deal found 9/1![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 am -
1 stop7h 21m
Wed 10/215:25 pm -
1 stop8h 41m
Deal found 9/1![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:55 pm -
1 stop8h 30m
Tue 9/297:15 am -
1 stop9h 51m
Deal found 9/1![Delta logo]()
$378
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:35 am -
1 stop7h 05m
Tue 10/207:00 am -
2 stops8h 45m
Deal found 9/2![Southwest logo]()
$385
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:40 pm -
2 stops10h 00m
Fri 10/91:05 pm -
1 stop12h 20m
Deal found 9/1![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 am -
1 stop8h 04m
Sat 10/31:36 pm -
1 stop7h 32m
Deal found 9/1![American Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:40 am -
2 stops9h 15m
Sat 10/311:20 am -
2 stops9h 50m
Deal found 8/31![Southwest logo]()
$417
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 am -
1 stop9h 37m
Fri 10/95:25 pm -
1 stop8h 41m
Deal found 8/31![American Airlines logo]()
$422
Best flights from San Francisco to GreenvilleDiscover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:40 pm -
1 stop8h 32m
Thu 12/177:25 pm -
1 stop7h 40m
Deal found 9/1![Delta logo]()
$361
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:25 pm -
1 stop9h 45m
Fri 11/276:40 am -
2 stops12h 00m
Deal found 8/28![Southwest logo]()
$455
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/309:40 pm -
1 stop10h 46m
Wed 2/37:00 am -
1 stop10h 50m
Deal found 9/1![United Airlines logo]()
$463
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:05 pm -
1 stop10h 25m
Sat 10/311:20 am -
2 stops9h 50m
Deal found 8/31![Southwest logo]()
$469
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:45 am -
2 stops10h 15m
Fri 10/91:05 pm -
2 stops10h 00m
Deal found 8/31![Southwest logo]()
$520
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:00 pm -
1 stop7h 35m
Mon 9/216:10 pm -
1 stop9h 20m
Deal found 8/28![United Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:58 pm -
2 stops9h 25m
Wed 10/215:40 am -
2 stops10h 28m
Deal found 8/30![Delta logo]()
$600
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am -
1 stop7h 08m
Wed 11/46:49 am -
2 stops14h 13m
Deal found 8/31![United Airlines logo]()
$606
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:45 am -
2 stops10h 15m
Sun 10/116:15 am -
2 stops10h 20m
Deal found 8/29![Southwest logo]()
$574
Last-minute flights from San Francisco to GreenvilleDiscover last-minute flight deals from San Francisco to Greenville. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Greenville. Data last updated September 2, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:55 pm -
1 stop8h 30m
Tue 9/297:15 am -
1 stop9h 51m
Deal found 9/1![Delta logo]()
$378
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:59 pm -
1 stop10h 00m
Wed 9/3011:04 am -
1 stop10h 05m
Deal found 9/2![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:12 am -
1 stop9h 47m
Sat 10/31:36 pm -
1 stop7h 32m
Deal found 8/31![American Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:40 am -
2 stops9h 15m
Sat 10/311:20 am -
2 stops9h 50m
Deal found 8/31![Southwest logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 am -
1 stop8h 04m
Sat 10/31:36 pm -
1 stop7h 32m
Deal found 9/1![American Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:40 pm -
2 stops10h 00m
Fri 10/91:05 pm -
1 stop12h 20m
Deal found 9/1![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 am -
1 stop9h 37m
Fri 10/95:25 pm -
1 stop8h 41m
Deal found 8/31![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 am -
1 stop7h 21m
Wed 10/215:25 pm -
1 stop8h 41m
Deal found 9/1![American Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:35 am -
1 stop7h 05m
Tue 10/207:00 am -
2 stops8h 45m
Deal found 9/2![Southwest logo]()
$385
One-way flights from San Francisco to GreenvilleSearch for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:30 pm -
1 stop6h 55m
Deal found 8/31![Delta logo]()
$169
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:50 am -
2 stops11h 10m
Deal found 8/31![Southwest logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:05 pm -
2 stops16h 09m
Deal found 8/31![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:14 pm -
2 stops30h 56m
Deal found 8/28![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:59 pm -
2 stops15h 31m
Deal found 8/31![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:25 pm -
3 stops45h 34m
Deal found 9/2![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:05 pm -
3 stops18h 39m
Deal found 8/28![Multiple Airlines logo]()
$211
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:30 pm -
1 stop8h 40m
Deal found 8/30![Southwest logo]()
$212
Find flight deals from San Francisco to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (American Airlines) |
One-way from | $169 (Delta) |
Popular in | May |
Cheapest in | January |
Average price | $424 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Tue 12/15
10:40 pm-10:12 am
1 stop8h 32m
Greenville
Thu 12/17
7:25 pm-12:05 am
1 stop7h 40m
$361
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Sun 11/22
9:25 pm-10:10 am
1 stop9h 45m
Greenville
Fri 11/27
6:40 am-3:40 pm
2 stops12h 00m
$455
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Sat 1/30
9:40 pm-11:26 am
1 stop10h 46m
Greenville
Wed 2/3
7:00 am-2:50 pm
1 stop10h 50m
$463
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 9/30
11:05 pm-12:30 pm
1 stop10h 25m
Greenville
Sat 10/3
11:20 am-6:10 pm
2 stops9h 50m
$469
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Mon 10/5
6:45 am-8:00 pm
2 stops10h 15m
Greenville
Fri 10/9
1:05 pm-8:05 pm
2 stops10h 00m
$520
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Thu 10/8
6:45 am-8:00 pm
2 stops10h 15m
Greenville
Sun 10/11
6:15 am-1:35 pm
2 stops10h 20m
$574
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 9/16
11:00 pm-9:35 am
1 stop7h 35m
Greenville
Mon 9/21
6:10 pm-12:30 am
1 stop9h 20m
$584
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 10/7
8:58 pm-9:23 am
2 stops9h 25m
Greenville
Wed 10/21
5:40 am-1:08 pm
2 stops10h 28m
$600
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 10/21
5:00 am-3:08 pm
1 stop7h 08m
Greenville
Wed 11/4
6:49 am-6:02 pm
2 stops14h 13m
$606
Cheapest one-way
Quickest one-way
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 9/9
11:30 pm-9:25 am
1 stop6h 55m
$169
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
SFO-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Greenville
What is the cheapest month to book a flight from San Francisco to Greenville?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $346). Flying from San Francisco to Greenville in May is currently the most expensive (average of $692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Greenville?
Airfare is below average for this route at the moment.
San Francisco to Greenville flights typically cost between $410 and $447 in September.The cheapest round-trip price found within the last 5 days was $337 on American Airlines (Sep 30-Oct 3).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 2, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Complete your trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
San Francisco and Greenville flights
Browse other San Francisco and Greenville flight options. Last updated on September 2, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Francisco to Greenville
Discover the top 3 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$339 | Average$503 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$353 | Average$562 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$424 | Average$544 | FlexibilityNo cancel fee | On-time69% |