$190+ Cheap flights from San Francisco to Greenville (SFO - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Greenville
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Best
Last-minute
One-way
Cheapest flights from San Francisco to GreenvilleExplore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:16 pm
SFO
- GSP
2 stops14h 37m
Multiple Airlines
Mon 5/1110:03 am
GSP
- SFO
1 stop14h 31m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:52 pm
SFO
- GSP
1 stop9h 02m
United Airlines
Wed 4/227:42 pm
GSP
- SFO
1 stop8h 35m
United Airlines
Deal found 3/10![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:20 am
SFO
- GSP
2 stops11h 20m
Southwest
Wed 4/221:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Deal found 3/10![Southwest logo]()
$372
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:14 am
SFO
- GSP
1 stop9h 34m
American Airlines
Thu 4/95:20 am
GSP
- SFO
1 stop9h 56m
American Airlines
Deal found 3/10![American Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:55 pm
SFO
- GSP
1 stop10h 05m
Southwest
Tue 4/71:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Deal found 3/9![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:52 pm
SFO
- GSP
1 stop7h 26m
American Airlines
Tue 5/266:41 pm
GSP
- SFO
1 stop8h 06m
American Airlines
Deal found 3/10![American Airlines logo]()
$393
Best flights from San Francisco to GreenvilleDiscover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1210:50 pm
SFO
- GSP
1 stop7h 55m
United Airlines
Tue 4/146:30 am
GSP
- SFO
1 stop9h 57m
United Airlines
Deal found 3/6![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:30 am
SFO
- GSP
2 stops8h 55m
Southwest
Tue 4/71:55 pm
GSP
- SFO
2 stops11h 15m
Southwest
Deal found 3/8![Southwest logo]()
$423
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:20 pm
SFO
- GSP
1 stop6h 34m
Delta
Fri 4/35:40 am
GSP
- SFO
1 stop10h 09m
Delta
Deal found 3/10![Delta logo]()
$547
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:55 pm
SFO
- GSP
1 stop7h 52m
United Airlines
Sun 5/37:35 pm
GSP
- SFO
1 stop8h 41m
United Airlines
Deal found 3/7![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:40 pm
SFO
- GSP
1 stop10h 20m
Southwest
Sun 5/106:30 am
GSP
- SFO
2 stops9h 05m
Southwest
Deal found 3/6![Southwest logo]()
$486
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:45 am
SFO
- GSP
1 stop8h 09m
United Airlines
Wed 4/155:41 pm
GSP
- SFO
1 stop9h 58m
United Airlines
Deal found 3/9![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:15 pm
SFO
- GSP
1 stop9h 55m
Southwest
Sun 4/266:30 am
GSP
- SFO
2 stops8h 40m
Southwest
Deal found 3/8![Southwest logo]()
$488
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:40 pm
SFO
- GSP
2 stops15h 12m
United Airlines
Thu 4/165:41 pm
GSP
- SFO
1 stop9h 58m
United Airlines
Deal found 3/8![United Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:05 am
SFO
- GSP
1 stop8h 55m
United Airlines
Tue 5/267:40 pm
GSP
- SFO
2 stops14h 55m
United Airlines
Deal found 3/6![United Airlines logo]()
$576
Last-minute flights from San Francisco to GreenvilleDiscover last-minute flight deals from San Francisco to Greenville. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Greenville. Data last updated March 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:55 pm
SFO
- GSP
1 stop10h 05m
Southwest
Tue 4/71:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Deal found 3/9![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:14 am
SFO
- GSP
1 stop9h 34m
American Airlines
Thu 4/95:20 am
GSP
- SFO
1 stop9h 56m
American Airlines
Deal found 3/10![American Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:15 pm
SFO
- GSP
1 stop9h 55m
Southwest
Tue 4/141:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Deal found 3/10![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1210:50 pm
SFO
- GSP
1 stop7h 55m
United Airlines
Tue 4/146:30 am
GSP
- SFO
1 stop9h 57m
United Airlines
Deal found 3/6![United Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:52 pm
SFO
- GSP
1 stop9h 02m
United Airlines
Wed 4/227:42 pm
GSP
- SFO
1 stop8h 35m
United Airlines
Deal found 3/10![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:20 am
SFO
- GSP
2 stops11h 20m
Southwest
Wed 4/221:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Deal found 3/10![Southwest logo]()
$372
One-way flights from San Francisco to GreenvilleSearch for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:15 am
SFO
- GSP
1 stop9h 00m
American Airlines
Deal found 3/6![American Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:15 pm
SFO
- GSP
1 stop12h 55m
Southwest
Deal found 3/10![Southwest logo]()
$195
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:05 am
SFO
- GSP
1 stop6h 56m
United Airlines
Deal found 3/5![United Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:16 pm
SFO
- GSP
3 stops17h 32m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$215
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:30 am
SFO
- GSP
1 stop8h 49m
American Airlines
Deal found 3/6![American Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:25 pm
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 3/6![Southwest logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:50 pm
SFO
- GSP
1 stop10h 04m
United Airlines
Deal found 3/8![United Airlines logo]()
$240
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:25 pm
SFO
- GSP
2 stops9h 30m
Southwest
Deal found 3/5![Southwest logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:04 pm
SFO
- GSP
3 stops41h 51m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
SFO
- GSP
2 stops35h 07m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:00 pm
SFO
- GSP
2 stops19h 38m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$263
Find flight deals from San Francisco to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $358 (Kiwi.com) |
One-way from | $190 (American Airlines) |
Popular in | February |
Cheapest in | January |
Average price | $434 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sun 4/12
10:50 pm-9:45 am
1 stop7h 55m
Greenville
Tue 4/14
6:30 am-1:27 pm
1 stop9h 57m
$413
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 4/4
5:30 am-5:25 pm
2 stops8h 55m
Greenville
Tue 4/7
1:55 pm-10:10 pm
2 stops11h 15m
$423
Quickest round-trip
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Thu 4/30
10:55 pm-9:47 am
1 stop7h 52m
Greenville
Sun 5/3
7:35 pm-1:16 am
1 stop8h 41m
$459
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Mon 4/13
12:45 am-11:54 am
1 stop8h 09m
Greenville
Wed 4/15
5:41 pm-12:39 am
1 stop9h 58m
$467
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 5/6
10:40 pm-12:00 pm
1 stop10h 20m
Greenville
Sun 5/10
6:30 am-12:35 pm
2 stops9h 05m
$486
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Fri 4/24
9:15 pm-10:10 am
1 stop9h 55m
Greenville
Sun 4/26
6:30 am-12:10 pm
2 stops8h 40m
$488
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 4/1
2:20 pm-11:54 pm
1 stop6h 34m
Greenville
Fri 4/3
5:40 am-12:49 pm
1 stop10h 09m
$547
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Mon 4/13
10:40 pm-4:52 pm
2 stops15h 12m
Greenville
Thu 4/16
5:41 pm-12:39 am
1 stop9h 58m
$567
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 5/23
5:05 am-5:00 pm
1 stop8h 55m
Greenville
Tue 5/26
7:40 pm-7:35 am
2 stops14h 55m
$576
Cheapest one-way
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 4/25
5:20 am-4:21 pm
1 stop8h 01m
$190
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
SFO-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Greenville
How far ahead should I book a flight from San Francisco to Greenville?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Greenville. Price data was last updated on March 6, 2026.
To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from San Francisco to Greenville?
Currently, November is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $183). Flying from San Francisco to Greenville in December is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 10, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsSimpsonville
Duncan
Greer
Seneca
Anderson
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
San Francisco and Greenville flights
Browse other San Francisco and Greenville flight options. Last updated on March 10, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Greenville
Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$440 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$506 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$313 | Average$434 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$424 | Average$574 | FlexibilityNo cancel fee | On-time69% |