HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$147+ Cheap flights from San Francisco to Greenville (SFO - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$327
(United Airlines)

One-way from

$147
(Kiwi.com)

Popular in

July

Cheapest in

September

Average price

$415
Provider with most accurate pricing for San Francisco-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Greenville flights.
Search Deals
From San Francisco to Greenville
Search Deals
One-way flight from San Francisco to Greenville
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Find flight deals from San Francisco to Greenville

Cheapest flights from San Francisco to Greenville
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1011:56 pmSFO - GSP
1 stop7h 20mUnited Airlines
Wed 2/2510:00 amGSP - SFO
1 stop10h 50mUnited Airlines
Deal found 1/6$327
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/912:17 amSFO - GSP
2 stops10h 00mAmerican Airlines
Wed 2/257:29 amGSP - SFO
1 stop9h 43mAmerican Airlines
Deal found 1/6$332
This Southwest deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:05 amSFO - GSP
2 stops10h 45mSouthwest
Wed 2/2510:05 amGSP - SFO
2 stops11h 00mSouthwest
Deal found 1/6$339
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:29 pmSFO - GSP
1 stop8h 27mAmerican Airlines
Tue 3/317:14 amGSP - SFO
1 stop10h 09mAmerican Airlines
Deal found 1/8$363
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:29 pmSFO - GSP
1 stop8h 27mAmerican Airlines
Mon 3/234:26 pmGSP - SFO
1 stop9h 50mAmerican Airlines
Deal found 1/6$394
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:25 amSFO - GSP
1 stop6h 50mAmerican Airlines
Thu 3/54:26 pmGSP - SFO
1 stop8h 41mAmerican Airlines
Deal found 1/7$395
This Southwest deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:00 amSFO - GSP
2 stops10h 00mSouthwest
Sun 2/1510:45 amGSP - SFO
1 stop8h 00mSouthwest
Deal found 1/7$400
This Southwest deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:25 pmSFO - GSP
2 stops9h 30mSouthwest
Tue 3/311:50 pmGSP - SFO
1 stop11h 15mSouthwest
Deal found 1/8$412
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1310:36 amSFO - GSP
1 stop8h 38mAmerican Airlines
Mon 2/167:29 amGSP - SFO
1 stop9h 43mAmerican Airlines
Deal found 1/6$417

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

San Francisco

Fly to

Greenville

Route

Depart

Return

Price

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 2/11

9:00 am-7:07 pm

1 stop7h 07m

Greenville

Wed 2/25

7:29 am-2:12 pm

1 stop9h 43m

$327

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 2/18

6:00 am-3:36 pm

1 stop6h 36m

Greenville

Wed 2/25

7:29 am-2:12 pm

1 stop9h 43m

$327

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 2/9

12:17 am-1:17 pm

2 stops10h 00m

Greenville

Wed 2/25

7:29 am-2:12 pm

1 stop9h 43m

$332

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 2/11

6:05 am-7:50 pm

2 stops10h 45m

Greenville

Wed 2/25

10:05 am-6:05 pm

2 stops11h 00m

$339

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 2/18

4:30 pm-10:10 am

2 stops14h 40m

Greenville

Wed 2/25

10:05 am-6:05 pm

2 stops11h 00m

$339

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Sat 3/28

11:29 pm-10:56 am

1 stop8h 27m

Greenville

Tue 3/31

7:14 am-2:23 pm

1 stop10h 09m

$363

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 3/19

11:29 pm-10:56 am

1 stop8h 27m

Greenville

Mon 3/23

4:26 pm-11:16 pm

1 stop9h 50m

$394

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Sun 3/1

10:36 am-10:14 pm

1 stop8h 38m

Greenville

Thu 3/5

3:58 pm-11:10 pm

1 stop10h 12m

$395

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 2/5

7:00 am-7:07 pm

1 stop9h 07m

Greenville

Sun 2/15

5:20 am-12:17 pm

1 stop9h 57m

$395

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Fri 1/30

8:23 pm-8:58 am

3 stops57h 35m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Showing 1-10 of 15 results
1
2

Compare providers for flights from San Francisco to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Greenville

How far ahead should I book a flight from San Francisco to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Greenville. Price data was last updated on January 2, 2026.

To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Greenville?

Currently, April is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $167). Flying from San Francisco to Greenville in December is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 8, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,025 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,139 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,095 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Greenville?

    American Airlines and Southwest can get you from San Francisco to Greenville in just under 7h 07m. Your travel time can differ by up to 3h 38m. San Francisco and Greenville are separated by a distance of 2227 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Francisco to Greenville round-trip?

    Cheapflights users have booked flights from San Francisco to Greenville round-trip from $236. Other airlines that can offer you cheap pricing are Delta, from $278, and Southwest, from $313. American Airlines is currently priced 50% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from San Francisco to Greenville one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $102. Delta flights start at $147 while deals on American Airlines start at $168 one-way.

  • Can I find deals for flights from San Francisco to Greenville that include hotel bookings?

    Yes. In addition to deals on San Francisco to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Greenville.

  • Can I find deals for business class flights from San Francisco to Greenville?

    Yes. Cheapflights offers flight deals from San Francisco to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Greenville?

    Currently, April is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $167). Flying from San Francisco to Greenville in December is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Charlotte flights
Ontario to Charlotte flights
Burbank to Charlotte flights
San Francisco to Charlotte flights
Los Angeles to Charleston flights
San Diego to Charlotte flights
Ontario to Charleston flights
San Francisco to Charleston flights
Las Vegas to Charlotte flights
Los Angeles to Savannah flights
Santa Ana to Charlotte flights
San Francisco to Savannah flights
Ontario to Savannah flights
San Diego to Charleston flights
Los Angeles to Greenville flights
Sacramento to Charlotte flights
Santa Ana to Charleston flights
Los Angeles to Myrtle Beach flights
Sacramento to Myrtle Beach flights
San Diego to Savannah flights
Las Vegas to Savannah flights
Sacramento to Charleston flights
Reno to Charlotte flights
San Jose to Charlotte flights
San Jose to Charleston flights
San Diego to Columbia flights
Ontario to Myrtle Beach flights
Ontario to Greenville flights
Las Vegas to Charleston flights
Long Beach to Charlotte flights
San Francisco to Myrtle Beach flights
Ontario to Columbia flights
San Diego to Myrtle Beach flights
San Francisco to Columbia flights
San Jose to Savannah flights
Las Vegas to Myrtle Beach flights
Reno to Charleston flights
Sacramento to Greenville flights
Las Vegas to Greenville flights
Sacramento to Columbia flights
Los Angeles to Columbia flights
Santa Ana to Savannah flights
Palm Springs to Charlotte flights
Fresno to Charlotte flights
San Jose to Greenville flights
Burbank to Charleston flights
Sacramento to Savannah flights
Oakland to Charlotte flights
San Diego to Greenville flights

Top 4 airlines flying from San Francisco to Greenville

Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$422FlexibilityNo cancel feeOn-time71%
DeltaCheapest$294Average$519FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$313Average$434FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$424Average$576FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.