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$138+ Cheap flights from San Francisco to Greenville (SFO - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Aug 16 — Aug 231
Sat 8/16
Sat 8/23
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Greenville are usually found in September or April, booked 32 days in advance, depart on a Saturday or Wednesday and return on a Wednesday

Cheap flight deals from San Francisco to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 11, 2025.

Round-trip from

$283
(American Airlines)

One-way from

$138
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$543
From San Francisco to Greenville
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One-way flight from San Francisco to Greenville
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Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from San Francisco to Greenville

Cheapest flights from San Francisco to Greenville
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/411:59 pmSFO - GSP
1 stop6h 40mAmerican Airlines
Tue 11/115:12 amGSP - SFO
1 stop8h 56mAmerican Airlines
Deal found 8/8$283
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:10 amSFO - GSP
1 stop9h 34mAmerican Airlines
Sat 9/66:33 pmGSP - SFO
1 stop7h 52mAmerican Airlines
Deal found 8/10$304
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/610:15 amSFO - GSP
2 stops9h 15mAmerican Airlines
Tue 9/96:02 amGSP - SFO
1 stop8h 28mAmerican Airlines
Deal found 8/9$309
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/118:58 amSFO - GSP
1 stop6h 53mAmerican Airlines
Mon 9/156:33 pmGSP - SFO
1 stop7h 42mAmerican Airlines
Deal found 8/9$325
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/24:45 pmSFO - GSP
2 stops14h 05mSouthwest
Sat 9/68:20 amGSP - SFO
2 stops11h 05mSouthwest
Deal found 8/10$335
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:20 pmSFO - GSP
2 stops13h 20mSouthwest
Sat 10/188:00 amGSP - SFO
1 stop14h 45mSouthwest
Deal found 8/8$341
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/69:50 pmSFO - GSP
1 stop8h 09mDelta
Wed 10/81:45 pmGSP - SFO
1 stop8h 01mDelta
Deal found 8/7$351
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/161:37 pmSFO - GSP
1 stop6h 57mDelta
Fri 9/267:45 pmGSP - SFO
1 stop7h 12mDelta
Deal found 8/8$355
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/168:00 amSFO - GSP
2 stops9h 25mAmerican Airlines
Fri 9/2610:25 amGSP - SFO
1 stop8h 04mAmerican Airlines
Deal found 8/8$360

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

San Francisco

Fly to

Greenville

Route

Depart

Return

Price

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 11/4

11:59 pm-9:39 am

1 stop6h 40m

Greenville

Tue 11/11

5:12 am-11:08 am

1 stop8h 56m

$283

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 9/2

6:10 am-6:44 pm

1 stop9h 34m

Greenville

Sat 9/6

6:33 pm-11:25 pm

1 stop7h 52m

$304

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Sat 9/6

10:15 am-10:30 pm

2 stops9h 15m

Greenville

Tue 9/9

6:02 am-11:30 am

1 stop8h 28m

$309

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 9/11

8:58 am-6:51 pm

1 stop6h 53m

Greenville

Mon 9/15

6:33 pm-11:15 pm

1 stop7h 42m

$325

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 9/2

4:45 pm-9:50 am

2 stops14h 05m

Greenville

Sat 9/6

8:20 am-4:25 pm

2 stops11h 05m

$335

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Sat 10/11

6:20 pm-10:40 am

2 stops13h 20m

Greenville

Sat 10/18

8:00 am-7:45 pm

1 stop14h 45m

$341

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 10/6

9:50 pm-8:59 am

1 stop8h 09m

Greenville

Wed 10/8

1:45 pm-6:46 pm

1 stop8h 01m

$351

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 9/16

1:37 pm-11:34 pm

1 stop6h 57m

Greenville

Fri 9/26

7:45 pm-11:57 pm

1 stop7h 12m

$355

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 9/16

8:00 am-8:25 pm

2 stops9h 25m

Greenville

Fri 9/26

10:25 am-3:29 pm

1 stop8h 04m

$360

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 9/23

12:47 am-10:56 am

1 stop7h 09m

$138

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/7

Showing 1-10 of 16 results
1
2

Best time to book a flight from San Francisco to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Greenville

How far ahead should I book a flight from San Francisco to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Greenville. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 32 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Greenville?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $329). Flying from San Francisco to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated August 11, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Food

7.1

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Food

7.1

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,248 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Food

7.1

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,979 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Food

7.1

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,920 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Food

7.1

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Food

7.1

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from San Francisco to Greenville round-trip?

    Cheapflights users have booked flights from San Francisco to Greenville round-trip from $283. American Airlines is currently priced 41% below the average price you’ll pay for this route.

  • Can I find deals for flights from San Francisco to Greenville that include hotel bookings?

    Yes. In addition to deals on San Francisco to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Greenville.

  • Can I find deals for business class flights from San Francisco to Greenville?

    Yes. Cheapflights offers flight deals from San Francisco to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Greenville?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $329). Flying from San Francisco to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 4 airlines flying from San Francisco to Greenville

Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$449FlexibilityNo cancel feeOn-time71%
DeltaCheapest$259Average$446FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$313Average$434FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$446Average$574FlexibilityNo cancel feeOn-time69%

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