$122+ Cheap flights from Massachusetts to Greenville (GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — GSP
Oct 31 — Nov 71
Round-trip
1 adult, Economy
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Find cheap flights from Massachusetts to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Massachusetts to Greenville
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Cheapest flights from Massachusetts to GreenvilleExplore the most affordable flight options available from Massachusetts to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
Explore the most affordable flight options available from Massachusetts to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:15 pm -
1 stop6h 09m
Wed 10/2111:01 am -
1 stop3h 57m
Deal found 9/26![Delta logo]()
$248
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop6h 01m
Mon 11/911:30 am -
1 stop6h 57m
Deal found 9/29![Delta logo]()
$253
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop4h 21m
Sat 10/316:20 am -
2 stops8h 12m
Deal found 9/28![United Airlines logo]()
$258
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:36 pm -
2 stops19h 35m
Wed 11/117:41 pm -
2 stops21h 26m
Deal found 10/1![American Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/28![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Wed 11/47:05 am -
1 stop10h 05m
Deal found 9/30![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Mon 11/28:50 pm -
2 stops11h 30m
Deal found 9/27![Southwest logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:59 am -
2 stops9h 13m
Fri 11/69:41 am -
1 stop23h 48m
Deal found 9/29![Multiple Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:35 am -
2 stops14h 00m
Mon 11/98:50 pm -
2 stops11h 30m
Deal found 9/30![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 am -
1 stop4h 36m
Sat 10/316:20 am -
2 stops8h 12m
Deal found 9/30![United Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:17 am -
1 stop4h 23m
Wed 12/3010:59 am -
1 stop7h 15m
Deal found 9/30![American Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:39 am -
1 stop6h 34m
Sat 10/312:00 pm -
1 stop5h 07m
Deal found 9/28![Delta logo]()
$306
Best flights from Massachusetts to GreenvilleDiscover carefully curated flight deals from Massachusetts to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
Discover carefully curated flight deals from Massachusetts to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:36 pm -
1 stop16h 41m
Wed 11/117:55 am -
1 stop9h 12m
Deal found 10/1![American Airlines logo]()
$248
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
1 stop4h 30m
Tue 10/271:25 pm -
2 stops8h 50m
Deal found 9/27![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1511:15 am -
1 stop4h 54m
Mon 1/186:20 pm -
1 stop5h 14m
Deal found 9/30![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:30 am -
1 stop4h 21m
Thu 11/125:40 am -
1 stop5h 11m
Deal found 9/30![United Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:00 pm -
1 stop7h 02m
Wed 11/185:40 am -
2 stops9h 39m
Deal found 9/26![Delta logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:36 pm -
2 stops21h 42m
Sun 12/138:35 pm -
2 stops20h 32m
Deal found 9/26![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:31 am -
1 stop5h 50m
Tue 11/1710:42 am -
2 stops7h 52m
Deal found 9/26![United Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:08 pm -
1 stop6h 07m
Sun 12/137:00 am -
2 stops8h 07m
Deal found 9/27![Delta logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
2 stops10h 56m
Mon 11/167:43 pm -
1 stop4h 16m
Deal found 9/27![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/262:20 pm -
2 stops8h 20m
Sat 2/2711:00 am -
2 stops9h 50m
Deal found 9/27![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:16 pm -
1 stop17h 24m
Mon 10/198:00 am -
1 stop8h 49m
Deal found 9/27![American Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:15 pm -
1 stop5h 32m
Mon 10/195:59 pm -
1 stop4h 25m
Deal found 9/28![Delta logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:16 pm -
2 stops18h 58m
Mon 10/268:33 pm -
2 stops20h 16m
Deal found 9/28![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/114:15 pm -
1 stop6h 09m
Thu 10/155:40 am -
2 stops9h 18m
Deal found 9/26![Delta logo]()
$522
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:15 pm -
1 stop6h 09m
Thu 10/2211:01 am -
1 stop3h 57m
Deal found 9/30![Delta logo]()
$533
Last-minute flights from Massachusetts to GreenvilleDiscover last-minute flight deals from Massachusetts to Greenville. Data last updated October 1, 2026 and is based on user searches.
Discover last-minute flight deals from Massachusetts to Greenville. Data last updated October 1, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:15 pm -
1 stop6h 09m
Wed 10/2111:01 am -
1 stop3h 57m
Deal found 9/26![Delta logo]()
$248
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop4h 29m
Fri 10/236:21 pm -
1 stop4h 12m
Deal found 9/28![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 am -
1 stop4h 36m
Sat 10/316:20 am -
2 stops8h 12m
Deal found 9/30![United Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:39 am -
1 stop6h 34m
Sat 10/312:00 pm -
1 stop5h 07m
Deal found 9/28![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:20 am -
2 stops10h 15m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/30![Southwest logo]()
$332
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop4h 21m
Sat 10/316:20 am -
2 stops8h 12m
Deal found 9/28![United Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/28![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Wed 11/47:05 am -
1 stop10h 05m
Deal found 9/30![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Mon 11/28:50 pm -
2 stops11h 30m
Deal found 9/27![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:39 am -
1 stop4h 41m
Tue 11/35:59 pm -
1 stop5h 21m
Deal found 9/30![Delta logo]()
$253
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:00 am -
2 stops7h 56m
Tue 11/37:43 pm -
1 stop4h 16m
Deal found 9/30![United Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:00 am -
2 stops7h 56m
Mon 11/27:43 pm -
1 stop4h 16m
Deal found 9/30![United Airlines logo]()
$323
One-way flights from Massachusetts to GreenvilleSearch for one-way flight options from Massachusetts to Greenville. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
Search for one-way flight options from Massachusetts to Greenville. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:15 pm -
1 stop6h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$122
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:30 am -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$127
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:55 am -
2 stops10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:34 pm -
1 stop22h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Allegiant Air logo]()
$136
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:35 am -
2 stops14h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:29 am -
1 stop30h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Allegiant Air logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:29 am -
1 stop22h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:34 pm -
2 stops31h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:19 am -
2 stops23h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$146
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:38 am -
2 stops6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![United Airlines logo]()
$160
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:16 pm -
2 stops22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$194
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/184:15 pm -
1 stop6h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Delta logo]()
$335
Find flight deals from Massachusetts to Greenville
Keep the following information in mind while searching for Massachusetts to Greenville flight deals. Data was last updated October 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $248 (Delta) |
One-way from | $122 (Delta) |
Popular in | December |
Cheapest in | September |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Massachusetts to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 1, 2026.
Use the filters below to find and compare flights from Massachusetts to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
WorcesterGreenville
ORH Worcester - GSP Greenville
ORHGSP
Worcester
Wed 10/21
4:15 pm-10:24 pm
1 stop6h 09m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$122
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 1/9
6:00 am-11:26 am
1 stop5h 26m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 11/14
5:57 pm-11:47 pm
1 stop5h 50m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Mon 10/26
5:30 am-1:00 pm
1 stop7h 30m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 1/9
5:35 am-5:25 pm
2 stops11h 50m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$132
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Wed 10/21
5:45 am-3:01 pm
2 stops9h 16m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 12/12
5:45 am-4:53 pm
2 stops11h 08m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Tue 10/20
12:57 pm-7:44 pm
3 stops30h 47m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
Quickest round-trip
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Wed 11/25
5:30 am-10:11 am
1 stop4h 41m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$240
WorcesterGreenville
ORH Worcester - GSP Greenville
ORHGSP
Worcester
Mon 11/9
5:36 pm-10:17 am
1 stop16h 41m
Greenville
Wed 11/11
7:55 am-5:07 pm
1 stop9h 12m
$248
Showing 1-10 of 31 resultsSorted by cheapest first
Best time to book a flight from Massachusetts to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Massachusetts with our price prediction graph.
ORH-GSP
BOS-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Massachusetts to Greenville
USMA-GSP
ORH-GSP
BOS-GSP
What is the cheapest month to book a flight from Massachusetts to Greenville?
Currently, September is the cheapest month in which you can book a flight from Massachusetts to Greenville (average of $268). Flying from Massachusetts to Greenville in December is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Massachusetts to Greenville?
Airfare is below average for this route at the moment.
Massachusetts to Greenville flights typically cost between $356 and $507 in November.The cheapest round-trip price found within the last 5 days was $253 on Delta (Nov 7-Nov 9).
How far ahead should I book a flight from Massachusetts to Greenville?
Booking 15 days in advance of your planned departure date is, on average, the best time to get cheap flights from Massachusetts to Greenville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Massachusetts to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Alternative routes for Massachusetts to Greenville
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Complete your trip
Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Massachusetts to Greenville by cabin class
Find flights from Massachusetts to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 1, 2026.
Massachusetts and Greenville flights
Browse other Massachusetts and Greenville flight options. Last updated on October 1, 2026.
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Massachusetts to Greenville flights
Consider these flights traveling from Massachusetts to Greenville.
Top 4 airlines flying from Massachusetts to Greenville
Discover the top 4 airlines that operate flights from Massachusetts to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$168 | Average$376 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$210 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$356 | Average$486 | FlexibilityNo cancel fee | On-time63% |