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Greenville

$172+ Cheap flights from Manchester, NH to Greenville (MHT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — GSP
Jun 17 — Jun 241
Wed 6/17
Wed 6/24
1 adult, Economy
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Cheap flight deals from Manchester to Greenville

Cheapest flights from Manchester to Greenville
Explore the most affordable flight options available from Manchester to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.

This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
MHT
-
GSP
1 stop6h 26m
American Airlines
Tue 7/146:32 pm
GSP
-
MHT
1 stop5h 05m
American Airlines
Deal found 5/13$291
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:10 am
MHT
-
GSP
1 stop4h 00m
Southwest
Tue 7/141:50 pm
GSP
-
MHT
1 stop8h 55m
Southwest
Deal found 5/17$296
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:11 pm
MHT
-
GSP
1 stop7h 03m
American Airlines
Tue 9/2911:15 am
GSP
-
MHT
1 stop5h 43m
American Airlines
Deal found 5/14$299
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:38 am
MHT
-
GSP
2 stops6h 32m
American Airlines
Tue 6/97:20 pm
GSP
-
MHT
1 stop4h 31m
American Airlines
Deal found 5/13$321
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
MHT
-
GSP
1 stop4h 24m
American Airlines
Mon 8/104:40 pm
GSP
-
MHT
1 stop7h 12m
American Airlines
Deal found 5/16$330
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:41 am
MHT
-
GSP
1 stop6h 43m
American Airlines
Wed 6/107:14 pm
GSP
-
MHT
1 stop4h 37m
American Airlines
Deal found 5/13$335
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:55 am
MHT
-
GSP
1 stop24h 02m
Multiple Airlines
Fri 9/182:18 pm
GSP
-
MHT
2 stops45h 26m
Multiple Airlines
Deal found 5/15$340
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:10 pm
MHT
-
GSP
1 stop6h 41m
American Airlines
Tue 7/146:32 pm
GSP
-
MHT
1 stop5h 05m
American Airlines
Deal found 5/13$349
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:51 pm
MHT
-
GSP
1 stop5h 00m
American Airlines
Tue 6/307:20 pm
GSP
-
MHT
1 stop4h 31m
American Airlines
Deal found 5/15$353

Find flight deals from Manchester to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(American Airlines)

One-way from

$172
(American Airlines)

Popular in

April

Cheapest in

January

Average price

$462
Provider with most accurate pricing for Manchester-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Greenville flights.
Search Deals
From Manchester to Greenville
Search Deals
One-way flight from Manchester to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Manchester to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 9/24

8:00 am-6:20 pm

2 stops10h 20m

Greenville

Mon 9/28

8:40 am-2:55 pm

1 stop6h 15m

$402
Quickest round-trip

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Fri 6/12

9:20 am-1:15 pm

1 stop3h 55m

Greenville

Fri 6/19

1:55 pm-6:25 pm

1 stop4h 30m

$417

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 8/29

9:25 am-2:19 pm

1 stop4h 54m

Greenville

Tue 9/1

7:00 am-2:08 pm

2 stops7h 08m

$424

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Fri 7/3

9:20 am-1:15 pm

1 stop3h 55m

Greenville

Sun 7/5

6:50 am-6:30 pm

2 stops11h 40m

$444

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 8/1

11:30 am-10:50 pm

2 stops11h 20m

Greenville

Sat 8/8

11:05 am-7:40 pm

2 stops8h 35m

$459

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 7/25

7:15 am-8:00 pm

2 stops12h 45m

Greenville

Mon 7/27

12:55 pm-12:05 am

2 stops11h 10m

$480

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 9/8

7:38 pm-9:50 am

1 stop14h 12m

Greenville

Sat 9/12

6:30 am-7:03 pm

2 stops12h 33m

$482

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Mon 9/14

7:41 pm-9:48 am

1 stop14h 07m

Greenville

Tue 9/22

7:00 am-2:08 pm

2 stops7h 08m

$497

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 5/30

6:00 am-4:35 pm

2 stops10h 35m

Greenville

Wed 6/3

6:45 am-3:05 pm

2 stops8h 20m

$497
Cheapest one-way

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 6/24

5:41 am-12:24 pm

1 stop6h 43m

$173

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Manchester to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Greenville in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Greenville

How far ahead should I book a flight from Manchester, New Hampshire to Greenville?

The best time to book flights from Manchester, New Hampshire to Greenville is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester, New Hampshire to Greenville?

Currently, January is the cheapest month in which you can book a flight from Manchester, New Hampshire to Greenville (average of $345). Flying from Manchester, New Hampshire to Greenville in April is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Manchester, New Hampshire to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 18, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Manchester to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,287 reviews

Food

7.0

Overall

7.9

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,287 reviews
Southwest
7.9
Good
4,287 reviews

Food

7.0

Overall

7.9

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,737 reviews
Southwest
7.9
Good
4,287 reviews

Food

7.0

Overall

7.9

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,648 reviews
Southwest
7.9
Good
4,287 reviews

Food

7.0

Overall

7.9

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Greenville?

    For as low as $359, United Airlines can have you in Greenville from Manchester, New Hampshire in 8h 46m. The distance between Manchester, New Hampshire and Greenville is about 801 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Manchester, New Hampshire to Greenville round-trip?

    According to our current data, American Airlines ($227), Southwest ($254), and United Airlines ($341) offers the cheapest pricing from Manchester, New Hampshire to Greenville. Users have found that American Airlines is 46% cheaper than the other options available to this destination.

  • Can I find deals for flights from Manchester to Greenville that include hotel bookings?

    Yes. In addition to deals on Manchester to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Greenville.

  • Can I find deals for business class flights from Manchester to Greenville?

    Yes. Cheapflights offers flight deals from Manchester to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Manchester, New Hampshire to Greenville (average of $345). Flying from Manchester, New Hampshire to Greenville in April is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Manchester to Greenville

Discover the top 3 airlines that operate flights from Manchester to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$227Average$399FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$254Average$437FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$339Average$421FlexibilityNo cancel feeOn-time69%

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