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$249+ Cheap flights from Gainesville to Greenville (GNV - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — GSP
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
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Cheap flight deals from Gainesville to Greenville

Cheapest flights from Gainesville to Greenville
Explore the most affordable flight options available from Gainesville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:30 amGNV - GSP
1 stop3h 41mAmerican Airlines
Sun 1/47:00 amGSP - GNV
1 stop3h 52mAmerican Airlines
Deal found 12/16$392
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amGNV - GSP
1 stop3h 19mDelta
Sat 1/37:59 pmGSP - GNV
1 stop4h 00mDelta
Deal found 12/14$407
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amGNV - GSP
2 stops8h 03mAmerican Airlines
Sat 1/36:20 pmGSP - GNV
1 stop4h 20mAmerican Airlines
Deal found 12/14$470
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:00 amGNV - GSP
1 stop3h 19mDelta
Fri 12/267:59 pmGSP - GNV
1 stop4h 00mDelta
Deal found 12/15$507

Find flight deals from Gainesville to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$307
(Delta)

One-way from

$249
(Delta)

Popular in

September

Cheapest in

February

Average price

$522
Provider with most accurate pricing for Gainesville Regional-Greenville flight deals.
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Provider most trusted by Cheapflights users for Gainesville Regional-Greenville flights.
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From Gainesville Regional to Greenville
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One-way flight from Gainesville Regional to Greenville
Search Deals
Highest demand for flights based on searches. 41% potential increase in price ($462 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($70 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Gainesville to Greenville that are best for you.

Fly from

Gainesville

Fly to

Greenville

Route

Depart

Return

Price

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Wed 1/14

6:00 am-11:08 am

1 stop5h 08m

Greenville

Wed 1/21

3:05 pm-6:10 pm

1 stop3h 05m

$307

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Fri 5/1

4:59 pm-9:25 pm

1 stop4h 26m

Greenville

Tue 5/5

3:00 pm-6:23 pm

1 stop3h 23m

$317

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Wed 1/14

6:00 am-3:14 pm

2 stops9h 14m

Greenville

Wed 1/21

7:03 am-12:30 pm

1 stop5h 27m

$352

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Wed 12/31

6:00 am-3:35 pm

2 stops9h 35m

Greenville

Sun 1/4

7:00 am-10:52 am

1 stop3h 52m

$397

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Tue 12/30

6:00 am-9:19 am

1 stop3h 19m

Greenville

Sat 1/3

7:59 pm-11:59 pm

1 stop4h 00m

$407

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Tue 12/30

6:00 am-2:03 pm

2 stops8h 03m

Greenville

Sat 1/3

6:20 pm-10:40 pm

1 stop4h 20m

$470

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Fri 5/1

5:58 pm-9:11 pm

1 stop3h 13m

Greenville

Tue 5/5

7:25 am-10:43 am

1 stop3h 18m

$478

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Thu 1/22

4:59 pm-9:52 pm

1 stop4h 53m

$249

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Mon 1/26

10:11 am-2:03 pm

1 stop3h 52m

$249

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Thu 1/22

6:00 am-3:14 pm

2 stops9h 14m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 11 results
1
2

Compare providers for flights from Gainesville to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Greenville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Gainesville-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Gainesville-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Greenville

What is the cheapest month to book a flight from Gainesville to Greenville?

Currently, February is the cheapest month in which you can book a flight from Gainesville to Greenville (average of $42). Flying from Gainesville to Greenville in June is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to GSP?

Find hourly flight availability from Gainesville to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

A simple way to save on the total cost of your ticket is to fly from Gainesville to Greenville in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated December 17, 2025.
Get a feel of what it's like to fly with Delta from Gainesville to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Greenville?

    Delta and American Airlines can get you from Gainesville to Greenville in just under 5h 08m. Your travel time can differ by up to 4h 06m. The distance from Gainesville to Greenville is about 359 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Gainesville to Greenville round-trip?

    Currently priced at $351, Delta will fly you from Gainesville to Greenville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Delta is priced at 45% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Gainesville to Greenville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Greenville.

  • Can I find deals for business class flights from Gainesville to Greenville?

    Yes. Cheapflights offers flight deals from Gainesville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Greenville?

    Currently, February is the cheapest month in which you can book a flight from Gainesville to Greenville (average of $42). Flying from Gainesville to Greenville in June is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top airline flying from Gainesville to Greenville

Discover the top airline that operate flights from Gainesville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$351Average$442FlexibilityNo cancel feeOn-timeN/A

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