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$293+ Cheap flights from Greenville to Gainesville (GSP - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — GNV
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
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Cheap flight deals from Greenville to Gainesville

Cheapest flights from Greenville to Gainesville
Explore the most affordable flight options available from Greenville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:45 am
GSP
-
GNV
1 stop3h 32m
Delta
Sun 10/187:03 pm
GNV
-
GSP
1 stop3h 48m
Delta
Deal found 7/27$377
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:49 am
GSP
-
GNV
1 stop6h 05m
Delta
Sat 8/151:08 pm
GNV
-
GSP
1 stop3h 07m
Delta
Deal found 7/27$457
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:12 pm
GSP
-
GNV
1 stop6h 39m
American Airlines
Mon 8/106:39 pm
GNV
-
GSP
1 stop4h 11m
American Airlines
Deal found 7/26$486
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:06 pm
GSP
-
GNV
1 stop3h 09m
Delta
Fri 8/73:41 pm
GNV
-
GSP
1 stop3h 28m
Delta
Deal found 7/26$598
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:10 pm
GSP
-
GNV
2 stops7h 49m
American Airlines
Sun 10/189:44 am
GNV
-
GSP
1 stop5h 37m
American Airlines
Deal found 7/25$608
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:52 am
GSP
-
GNV
2 stops11h 17m
American Airlines
Sat 8/156:15 am
GNV
-
GSP
2 stops8h 32m
American Airlines
Deal found 7/27$625
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:10 am
GSP
-
GNV
1 stop6h 10m
American Airlines
Mon 8/176:15 am
GNV
-
GSP
2 stops10h 26m
American Airlines
Deal found 7/29$648
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:07 pm
GSP
-
GNV
2 stops7h 52m
American Airlines
Fri 8/75:45 am
GNV
-
GSP
1 stop5h 37m
American Airlines
Deal found 7/26$705
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:34 am
GSP
-
GNV
2 stops11h 16m
American Airlines
Sun 9/207:34 pm
GNV
-
GSP
2 stops14h 49m
American Airlines
Deal found 7/29$779

Find flight deals from Greenville to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$377
(Delta)

One-way from

$293
(American Airlines)
Provider with most accurate pricing for Greenville-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Gainesville Regional flights.
Search Deals
From Greenville to Gainesville Regional
Search Deals
One-way flight from Greenville to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Greenville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Thu 8/27

6:55 am-12:23 pm

1 stop5h 28m

Gainesville Regional

Thu 9/3

5:35 pm-10:59 pm

1 stop5h 24m

$377
Quickest round-trip

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 10/16

11:45 am-3:17 pm

1 stop3h 32m

Gainesville Regional

Sun 10/18

7:03 pm-10:51 pm

1 stop3h 48m

$377

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Wed 8/12

8:49 am-2:54 pm

1 stop6h 05m

Gainesville Regional

Sun 8/16

7:01 pm-10:59 pm

1 stop3h 58m

$457

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Tue 8/11

8:49 am-2:54 pm

1 stop6h 05m

Gainesville Regional

Sat 8/15

1:08 pm-4:15 pm

1 stop3h 07m

$457

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Wed 8/5

3:12 pm-9:51 pm

1 stop6h 39m

Gainesville Regional

Mon 8/10

6:39 pm-10:50 pm

1 stop4h 11m

$486

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Thu 8/13

8:10 am-2:20 pm

1 stop6h 10m

Gainesville Regional

Mon 8/17

6:15 am-4:41 pm

2 stops10h 26m

$648

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Wed 8/12

5:19 pm-11:59 pm

2 stops6h 40m

Gainesville Regional

Sun 8/16

6:15 am-2:11 pm

2 stops7h 56m

$697

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Tue 9/15

10:34 am-9:50 pm

2 stops11h 16m

Gainesville Regional

Sun 9/20

7:34 pm-10:23 am

2 stops14h 49m

$779
Cheapest one-way
Quickest one-way

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Tue 8/25

10:12 am-2:20 pm

1 stop4h 08m

$293

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Tue 8/4

6:18 pm-12:16 am

1 stop5h 58m

$403

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Sorted by cheapest first

Compare providers for flights from Greenville to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Gainesville in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Gainesville?

    For as low as $377, Delta can have you in Gainesville from Greenville in 5h 28m. The distance between Greenville and Gainesville is about 359 mi.

  • Can I find deals for flights from Greenville to Gainesville that include hotel bookings?

    Yes. In addition to deals on Greenville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Gainesville.

  • Can I find deals for business class flights from Greenville to Gainesville?

    Yes. Cheapflights offers flight deals from Greenville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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