$273+ Cheap flights from Gainesville (GNV) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Gainesville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Gainesville to South CarolinaExplore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:03 am -
1 stop3h 20m
Tue 10/131:45 pm -
1 stop4h 29m
Deal found 9/7![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:31 pm -
1 stop4h 48m
Sat 11/285:40 am -
1 stop3h 51m
Deal found 9/10![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:03 pm -
1 stop3h 48m
Sun 10/115:40 am -
1 stop3h 54m
Deal found 9/7![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:07 am -
Nonstop1h 52m
Wed 12/309:05 am -
Nonstop1h 43m
Deal found 9/10![American Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop4h 48m
Tue 10/134:42 pm -
1 stop7h 17m
Deal found 9/8![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am -
1 stop3h 20m
Mon 9/285:45 am -
1 stop3h 46m
Deal found 9/9![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:10 pm -
1 stop4h 18m
Tue 9/296:00 am -
1 stop3h 31m
Deal found 9/9![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:00 pm -
1 stop5h 12m
Wed 12/308:45 am -
1 stop5h 30m
Deal found 9/7![Delta logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 pm -
Nonstop1h 48m
Sat 10/105:15 pm -
Nonstop1h 37m
Deal found 9/8![American Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 pm -
Nonstop1h 48m
Sat 12/262:55 pm -
Nonstop1h 40m
Deal found 9/8![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:39 pm -
Nonstop1h 54m
Tue 9/158:40 am -
Nonstop1h 39m
Deal found 9/8![American Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops9h 21m
Tue 10/136:32 am -
1 stop3h 47m
Deal found 9/7![American Airlines logo]()
$526
Best flights from Gainesville to South CarolinaDiscover carefully curated flight deals from Gainesville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Gainesville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:03 am -
1 stop3h 20m
Tue 10/131:45 pm -
1 stop4h 29m
Deal found 9/7![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:07 am -
Nonstop1h 52m
Wed 12/309:05 am -
Nonstop1h 43m
Deal found 9/10![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:02 pm -
1 stop4h 19m
Sun 10/185:40 am -
1 stop3h 54m
Deal found 9/9![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:00 pm -
Nonstop1h 48m
Tue 10/138:40 am -
Nonstop1h 39m
Deal found 9/8![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:31 pm -
1 stop4h 48m
Sat 11/285:40 am -
1 stop3h 51m
Deal found 9/10![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:00 pm -
1 stop5h 12m
Sun 11/155:40 am -
1 stop3h 51m
Deal found 9/11![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop4h 48m
Tue 10/274:42 pm -
1 stop7h 17m
Deal found 9/8![American Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop6h 03m
Sat 10/107:47 pm -
1 stop4h 12m
Deal found 9/8![American Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:00 pm -
1 stop5h 12m
Wed 12/308:45 am -
1 stop5h 30m
Deal found 9/8![Delta logo]()
$443
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:34 pm -
Nonstop1h 53m
Mon 10/127:30 am -
Nonstop1h 39m
Deal found 9/11![American Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am -
1 stop3h 20m
Mon 9/285:45 am -
1 stop3h 46m
Deal found 9/9![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:10 pm -
1 stop4h 18m
Tue 9/296:00 am -
1 stop3h 31m
Deal found 9/9![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops9h 21m
Tue 10/136:32 am -
1 stop3h 47m
Deal found 9/7![American Airlines logo]()
$526
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:53 am -
1 stop6h 02m
Tue 9/291:56 pm -
2 stops9h 29m
Deal found 9/9![American Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2510:10 am -
1 stop3h 56m
Wed 12/307:30 am -
1 stop3h 55m
Deal found 9/7![Delta logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:44 am -
Nonstop1h 51m
Thu 10/227:30 am -
Nonstop1h 39m
Deal found 9/7![American Airlines logo]()
$544
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:02 pm -
1 stop5h 43m
Sun 10/255:30 am -
1 stop4h 04m
Deal found 9/10![Delta logo]()
$525
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:28 pm -
1 stop4h 33m
Sun 10/185:30 am -
1 stop4h 04m
Deal found 9/8![Delta logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:33 am -
1 stop3h 47m
Wed 9/306:30 am -
1 stop3h 49m
Deal found 9/11![American Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:00 pm -
1 stop5h 02m
Tue 10/138:13 am -
1 stop6h 14m
Deal found 9/11![American Airlines logo]()
$650
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:00 pm -
1 stop5h 50m
Sun 10/45:45 am -
1 stop3h 46m
Deal found 9/10![Delta logo]()
$684
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:53 am -
1 stop5h 51m
Mon 9/283:32 pm -
2 stops7h 53m
Deal found 9/9![American Airlines logo]()
$705
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
2 stops9h 42m
Mon 10/124:12 pm -
2 stops7h 47m
Deal found 9/10![American Airlines logo]()
$837
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
2 stops8h 02m
Sat 11/289:35 am -
1 stop5h 07m
Deal found 9/10![American Airlines logo]()
$848
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
2 stops9h 21m
Sun 10/114:10 pm -
2 stops7h 49m
Deal found 9/7![American Airlines logo]()
$887
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
2 stops9h 07m
Sun 10/412:42 pm -
1 stop6h 10m
Deal found 9/10![American Airlines logo]()
$1,046
Last-minute flights from Gainesville to South CarolinaDiscover last-minute flight deals from Gainesville to South Carolina. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to South Carolina. Data last updated September 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:53 am -
Nonstop1h 42m
Wed 9/232:21 pm -
Nonstop1h 37m
Deal found 9/9![American Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am -
1 stop3h 20m
Mon 9/285:45 am -
1 stop3h 46m
Deal found 9/9![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:10 pm -
1 stop4h 18m
Tue 9/296:00 am -
1 stop3h 31m
Deal found 9/9![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:03 am -
1 stop3h 20m
Tue 10/131:45 pm -
1 stop4h 29m
Deal found 9/7![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops9h 21m
Tue 10/136:32 am -
1 stop3h 47m
Deal found 9/7![American Airlines logo]()
$526
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 pm -
Nonstop1h 48m
Sat 10/105:15 pm -
Nonstop1h 37m
Deal found 9/8![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:03 pm -
1 stop3h 48m
Sun 10/115:40 am -
1 stop3h 54m
Deal found 9/7![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:34 pm -
Nonstop1h 53m
Fri 10/167:30 am -
Nonstop1h 39m
Deal found 9/9![American Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:34 pm -
Nonstop1h 53m
Wed 10/145:15 pm -
Nonstop1h 37m
Deal found 9/9![American Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:34 pm -
Nonstop1h 53m
Tue 10/137:47 pm -
1 stop4h 12m
Deal found 9/8![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop50h 25m
Mon 10/1211:29 am -
Nonstop1h 52m
Deal found 9/11![American Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop51h 12m
Sun 11/111:30 am -
Nonstop1h 44m
Deal found 9/8![American Airlines logo]()
$499
One-way flights from Gainesville to South CarolinaSearch for one-way flight options from Gainesville to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Gainesville to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1510:20 am -
1 stop5h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$273
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:34 pm -
Nonstop1h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$288
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 pm -
2 stops15h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$308
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 pm -
2 stops15h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:15 am -
Nonstop1h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/64:59 pm -
2 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$345
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 pm -
2 stops15h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:08 pm -
2 stops18h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:00 pm -
2 stops18h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:39 pm -
1 stop6h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/156:00 am -
2 stops7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$580
Find flight deals from Gainesville to South Carolina
Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $377 (Delta) |
One-way from | $273 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GainesvilleGreenville
GNV Gainesville Regional - GSP Greenville
GNVGSP
Gainesville Regional
Fri 1/15
10:20 am-4:09 pm
1 stop5h 49m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$273
GainesvilleMyrtle Beach
GNV Gainesville Regional - MYR Myrtle Beach Intl
GNVMYR
Gainesville Regional
Mon 10/19
6:15 am-11:01 am
1 stop4h 46m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$273
GainesvilleCharlotte
GNV Gainesville Regional - CLT Charlotte Douglas
GNVCLT
Gainesville Regional
Sat 11/7
5:00 pm-8:18 am
2 stops15h 18m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$308
GainesvilleCharlotte
GNV Gainesville Regional - CLT Charlotte Douglas
GNVCLT
Gainesville Regional
Fri 11/13
7:06 pm-6:45 pm
2 stops23h 39m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$359
GainesvilleCharlotte
GNV Gainesville Regional - CLT Charlotte Douglas
GNVCLT
Gainesville Regional
Sat 3/6
4:59 pm-1:14 pm
2 stops20h 15m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$365
GainesvilleCharlotte
GNV Gainesville Regional - CLT Charlotte Douglas
GNVCLT
Gainesville Regional
Fri 3/5
7:05 pm-6:16 pm
2 stops23h 11m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$369
GainesvilleCharlotte
GNV Gainesville Regional - CLT Charlotte Douglas
GNVCLT
Gainesville Regional
Sat 12/12
5:00 pm-11:28 am
2 stops18h 28m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$374
GainesvilleGreenville
GNV Gainesville Regional - GSP Greenville
GNVGSP
Gainesville Regional
Wed 10/7
6:03 am-9:23 am
1 stop3h 20m
Greenville
Tue 10/13
1:45 pm-6:14 pm
1 stop4h 29m
$377
GainesvilleGreenville
GNV Gainesville Regional - GSP Greenville
GNVGSP
Gainesville Regional
Fri 10/9
4:02 pm-8:21 pm
1 stop4h 19m
Greenville
Sun 10/18
5:40 am-9:34 am
1 stop3h 54m
$377
GainesvilleCharlotte
GNV Gainesville Regional - CLT Charlotte Douglas
GNVCLT
Gainesville Regional
Fri 12/4
7:08 pm-10:03 am
2 stops14h 55m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$379
Showing 1-10 of 40 resultsSorted by cheapest first
Best time to book a flight from Gainesville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
GNV-GSP
GNV-MYR
GNV-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Gainesville to South Carolina
GNV-USSC
GNV-GSP
GNV-MYR
GNV-CLT
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 12, 2026.
Read through reviews of airlines operating flights from Gainesville to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Overall
7.1
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Related info for your journey
Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Gainesville to South Carolina
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Complete your trip
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Gainesville and South Carolina flights
Browse other Gainesville and South Carolina flight options. Last updated on September 12, 2026.
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Gainesville to South Carolina flights
Consider these flights traveling from Gainesville to South Carolina.
Top airline flying from Gainesville to South Carolina
Discover the top airline that operate flights from Gainesville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$472 | Average$584 | FlexibilityNo cancel fee | On-time71% |