$202+ Cheap flights from Gainesville (GNV) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Gainesville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Gainesville to South Carolina
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Cheapest flights from Gainesville to South CarolinaExplore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
GNV
- GSP
1 stop3h 28m
Delta
Tue 9/85:45 am
GSP
- GNV
1 stop3h 46m
Delta
Deal found 7/27![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
GNV
- GSP
1 stop3h 28m
Delta
Sun 9/65:20 pm
GSP
- GNV
1 stop5h 28m
Delta
Deal found 7/27![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:39 pm
GNV
- MYR
1 stop4h 29m
American Airlines
Fri 9/185:45 pm
MYR
- GNV
1 stop4h 05m
American Airlines
Deal found 7/28![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:12 am
GNV
- GSP
1 stop3h 43m
Delta
Sun 9/66:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/27![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:51 pm
GNV
- GSP
1 stop3h 45m
American Airlines
Sat 8/225:19 pm
GSP
- GNV
1 stop4h 26m
American Airlines
Deal found 7/28![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:00 pm
GNV
- CLT
Nonstop1h 50m
American Airlines
Wed 12/235:58 pm
CLT
- GNV
Nonstop1h 39m
American Airlines
Deal found 7/26![American Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:01 pm
GNV
- GSP
1 stop3h 58m
Delta
Mon 9/76:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/29![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:00 pm
GNV
- CLT
1 stop4h 14m
Delta
Sat 10/249:00 am
CLT
- GNV
1 stop3h 48m
Delta
Deal found 7/27![Delta logo]()
$423
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:39 pm
GNV
- MYR
1 stop3h 59m
American Airlines
Fri 8/2112:14 pm
MYR
- GNV
1 stop5h 54m
American Airlines
Deal found 7/27![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:39 pm
GNV
- CLT
Nonstop1h 54m
American Airlines
Tue 9/88:10 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/29![American Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:15 am
GNV
- CLT
1 stop3h 17m
Delta
Wed 12/235:25 am
CLT
- GNV
1 stop3h 59m
Delta
Deal found 7/29![Delta logo]()
$443
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:45 am
GNV
- CLT
Nonstop1h 49m
American Airlines
Mon 9/78:10 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/26![American Airlines logo]()
$444
Best flights from Gainesville to South CarolinaDiscover carefully curated flight deals from Gainesville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Gainesville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:35 pm
GNV
- GSP
1 stop4h 55m
Delta
Sun 9/68:59 am
GSP
- GNV
1 stop3h 14m
Delta
Deal found 7/27![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:51 pm
GNV
- GSP
1 stop3h 45m
American Airlines
Sat 8/225:19 pm
GSP
- GNV
1 stop4h 26m
American Airlines
Deal found 7/24![American Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
GNV
- GSP
1 stop4h 40m
Delta
Sat 9/511:00 am
GSP
- GNV
1 stop5h 42m
Delta
Deal found 7/27![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:41 pm
GNV
- GSP
1 stop3h 28m
Delta
Sun 9/68:59 am
GSP
- GNV
1 stop3h 14m
Delta
Deal found 7/27![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:39 pm
GNV
- MYR
1 stop3h 59m
American Airlines
Fri 8/2112:14 pm
MYR
- GNV
1 stop5h 54m
American Airlines
Deal found 7/27![American Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:00 pm
GNV
- GSP
1 stop4h 14m
Delta
Sat 10/247:45 am
GSP
- GNV
1 stop4h 59m
Delta
Deal found 7/24![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:39 pm
GNV
- CLT
Nonstop1h 49m
American Airlines
Sun 9/138:55 pm
CLT
- GNV
Nonstop1h 40m
American Airlines
Deal found 7/28![American Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:08 pm
GNV
- GSP
1 stop3h 07m
Delta
Sun 8/232:51 pm
GSP
- GNV
1 stop3h 25m
Delta
Deal found 7/27![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:45 am
GNV
- CLT
Nonstop1h 49m
American Airlines
Mon 9/78:10 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/28![American Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:01 pm
GNV
- GSP
1 stop3h 58m
Delta
Mon 9/76:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/29![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
GNV
- CLT
1 stop4h 20m
American Airlines
Sun 9/136:30 pm
CLT
- GNV
1 stop4h 55m
American Airlines
Deal found 7/29![American Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am
GNV
- CLT
1 stop6h 10m
American Airlines
Mon 9/144:35 pm
CLT
- GNV
1 stop6h 50m
American Airlines
Deal found 7/26![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:00 pm
GNV
- CLT
1 stop4h 14m
Delta
Sat 10/249:00 am
CLT
- GNV
1 stop3h 48m
Delta
Deal found 7/27![Delta logo]()
$423
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:51 pm
GNV
- CLT
Nonstop1h 47m
American Airlines
Wed 8/128:10 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/24![American Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:57 pm
GNV
- MYR
1 stop4h 31m
Delta
Sun 9/206:00 am
MYR
- GNV
1 stop3h 31m
Delta
Deal found 7/28![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:45 am
GNV
- CLT
1 stop4h 38m
American Airlines
Sat 8/154:25 pm
CLT
- GNV
Nonstop1h 43m
American Airlines
Deal found 7/27![American Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
GNV
- GSP
1 stop5h 02m
Delta
Sat 8/156:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/27![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:44 am
GNV
- CLT
Nonstop1h 46m
American Airlines
Mon 9/78:30 am
CLT
- GNV
Nonstop1h 39m
American Airlines
Deal found 7/29![American Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:08 pm
GNV
- CLT
1 stop5h 10m
Delta
Sat 8/299:00 am
CLT
- GNV
1 stop3h 23m
Delta
Deal found 7/28![Delta logo]()
$464
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:33 am
GNV
- MYR
1 stop3h 47m
American Airlines
Sun 9/205:00 am
MYR
- GNV
1 stop4h 08m
American Airlines
Deal found 7/26![American Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:12 am
GNV
- GSP
1 stop6h 03m
Delta
Tue 9/810:10 am
GSP
- GNV
1 stop5h 51m
Delta
Deal found 7/27![Delta logo]()
$545
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am
GNV
- MYR
2 stops7h 26m
American Airlines
Fri 9/185:45 pm
MYR
- GNV
1 stop4h 05m
American Airlines
Deal found 7/28![American Airlines logo]()
$546
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:34 pm
GNV
- GSP
1 stop4h 24m
American Airlines
Sun 10/2510:03 am
GSP
- GNV
1 stop6h 25m
American Airlines
Deal found 7/24![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:34 pm
GNV
- GSP
1 stop4h 24m
American Airlines
Sat 10/243:58 pm
GSP
- GNV
2 stops8h 01m
American Airlines
Deal found 7/24![American Airlines logo]()
$604
Last-minute flights from Gainesville to South CarolinaDiscover last-minute flight deals from Gainesville to South Carolina. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to South Carolina. Data last updated July 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:51 pm
GNV
- CLT
Nonstop1h 47m
American Airlines
Wed 8/128:10 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/24![American Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
GNV
- GSP
1 stop5h 02m
Delta
Sat 8/156:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/27![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:39 pm
GNV
- MYR
1 stop3h 59m
American Airlines
Fri 8/2112:14 pm
MYR
- GNV
1 stop5h 54m
American Airlines
Deal found 7/27![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:39 pm
GNV
- CLT
Nonstop1h 54m
American Airlines
Tue 9/88:10 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/29![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:51 pm
GNV
- GSP
1 stop3h 45m
American Airlines
Sat 8/225:19 pm
GSP
- GNV
1 stop4h 26m
American Airlines
Deal found 7/28![American Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:01 pm
GNV
- GSP
1 stop3h 58m
Delta
Tue 9/85:45 am
GSP
- GNV
1 stop3h 46m
Delta
Deal found 7/27![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:12 am
GNV
- GSP
1 stop3h 43m
Delta
Sun 9/66:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/27![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:45 am
GNV
- CLT
Nonstop1h 49m
American Airlines
Sun 9/65:15 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/29![American Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:45 am
GNV
- CLT
Nonstop1h 49m
American Airlines
Mon 9/76:00 pm
CLT
- GNV
1 stop5h 59m
American Airlines
Deal found 7/29![American Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:01 pm
GNV
- GSP
1 stop3h 58m
Delta
Mon 9/76:00 am
GSP
- GNV
1 stop3h 23m
Delta
Deal found 7/29![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:45 am
GNV
- CLT
Nonstop1h 49m
American Airlines
Sat 8/298:04 pm
CLT
- GNV
Nonstop1h 41m
American Airlines
Deal found 7/29![American Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:08 pm
GNV
- CLT
1 stop5h 10m
Delta
Sat 8/299:00 am
CLT
- GNV
1 stop3h 23m
Delta
Deal found 7/28![Delta logo]()
$464
One-way flights from Gainesville to South CarolinaSearch for one-way flight options from Gainesville to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Gainesville to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:39 pm
GNV
- CLT
Nonstop1h 49m
American Airlines
Deal found 7/28![American Airlines logo]()
$202
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
GNV
- CLT
1 stop6h 06m
American Airlines
Deal found 7/28![American Airlines logo]()
$212
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:03 pm
GNV
- GSP
1 stop3h 48m
Delta
Deal found 7/27![Delta logo]()
$273
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 pm
GNV
- CLT
2 stops15h 33m
Delta
Deal found 7/28![Delta logo]()
$298
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:08 pm
GNV
- CLT
2 stops22h 07m
Delta
Deal found 7/29![Delta logo]()
$318
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:10 pm
GNV
- CLT
2 stops14h 50m
Delta
Deal found 7/27![Delta logo]()
$320
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:35 pm
GNV
- CLT
2 stops15h 46m
Delta
Deal found 7/25![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:41 pm
GNV
- CLT
2 stops18h 35m
Delta
Deal found 7/25![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:01 pm
GNV
- CLT
2 stops18h 08m
Delta
Deal found 7/28![Delta logo]()
$341
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:44 am
GNV
- GSP
1 stop5h 37m
American Airlines
Deal found 7/27![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/134:50 pm
GNV
- GSP
2 stops17h 14m
American Airlines
Deal found 7/25![American Airlines logo]()
$652
Find flight deals from Gainesville to South Carolina
Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $367 (Delta) |
One-way from | $202 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Sat 8/22
5:35 pm-10:30 pm
1 stop4h 55m
Greenville
Sun 9/6
8:59 am-12:13 pm
1 stop3h 14m
$387
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Thu 8/20
6:00 am-10:40 am
1 stop4h 40m
Greenville
Sat 9/5
11:00 am-4:42 pm
1 stop5h 42m
$387
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Thu 8/20
3:41 pm-7:09 pm
1 stop3h 28m
Greenville
Sun 9/6
8:59 am-12:13 pm
1 stop3h 14m
$387
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Fri 10/23
4:00 pm-8:14 pm
1 stop4h 14m
Greenville
Sat 10/24
7:45 am-12:44 pm
1 stop4h 59m
$387
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Wed 8/19
2:51 pm-6:36 pm
1 stop3h 45m
Greenville
Sat 8/22
5:19 pm-9:45 pm
1 stop4h 26m
$397
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Thu 8/20
1:08 pm-4:15 pm
1 stop3h 07m
Greenville
Sun 8/23
2:51 pm-6:16 pm
1 stop3h 25m
$397
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Sun 8/23
7:01 pm-10:59 pm
1 stop3h 58m
Greenville
Mon 9/7
6:00 am-9:23 am
1 stop3h 23m
$407
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Wed 10/21
4:00 pm-8:14 pm
1 stop4h 14m
Charlotte Douglas
Sat 10/24
9:00 am-12:48 pm
1 stop3h 48m
$423
GainesvilleMyrtle Beach
GNV - MYR
GNVMYR
Gainesville Regional
Fri 8/14
6:39 pm-10:38 pm
1 stop3h 59m
Myrtle Beach Intl
Fri 8/21
12:14 pm-6:08 pm
1 stop5h 54m
$427
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Fri 9/11
4:39 pm-6:28 pm
Nonstop1h 49m
Charlotte Douglas
Sun 9/13
8:55 pm-10:35 pm
Nonstop1h 40m
$444
Showing 1-10 of 34 resultsSorted by cheapest first
Best time to book a flight from Gainesville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
GNV-GSP
GNV-CLT
GNV-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Gainesville to South Carolina
GNV-USSC
GNV-GSP
GNV-CLT
GNV-MYR
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2026.
Read through reviews of airlines operating flights from Gainesville to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Entertainment
6.8
Overall
7.1
Food
6.4
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Crew
7.9
Entertainment
6.8
Overall
7.1
Food
6.4
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Related info for your journey
Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Gainesville to South Carolina
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Complete your trip
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Gainesville and South Carolina flights
Browse other Gainesville and South Carolina flight options. Last updated on July 29, 2026.
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Gainesville to South Carolina flights
Consider these flights traveling from Gainesville to South Carolina.
Top airline flying from Gainesville to South Carolina
Discover the top airline that operate flights from Gainesville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$472 | Average$584 | FlexibilityNo cancel fee | On-time71% |