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South Carolina

$268+ Cheap flights from Gainesville (GNV) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
Jul 11 — Jul 181
Sat 7/11
Sat 7/18
1 adult, Economy
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Cheap flight deals from Gainesville to South Carolina

Cheapest flights from Gainesville to South Carolina
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.

This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
GNV
-
GSP
1 stop3h 18m
Delta
Wed 8/125:46 am
GSP
-
GNV
1 stop3h 37m
Delta
Deal found 6/8$357
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:01 pm
GNV
-
MYR
1 stop4h 54m
Delta
Tue 7/216:00 am
MYR
-
GNV
1 stop6h 23m
Delta
Deal found 6/9$357
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:01 pm
GNV
-
GSP
1 stop4h 53m
Delta
Tue 7/146:45 am
GSP
-
GNV
1 stop5h 38m
Delta
Deal found 6/9$367
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:37 pm
GNV
-
MYR
1 stop4h 30m
Delta
Sat 9/56:00 am
MYR
-
GNV
1 stop3h 23m
Delta
Deal found 6/7$367
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/51:48 pm
GNV
-
MYR
1 stop3h 59m
American Airlines
Sat 7/118:44 pm
MYR
-
GNV
1 stop3h 32m
American Airlines
Deal found 6/9$377
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:33 am
GNV
-
GSP
1 stop5h 45m
Delta
Mon 7/65:44 am
GSP
-
GNV
1 stop3h 46m
Delta
Deal found 6/8$387
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:32 pm
GNV
-
CLT
Nonstop1h 50m
American Airlines
Wed 7/2210:33 pm
CLT
-
GNV
Nonstop1h 43m
American Airlines
Deal found 6/9$393
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:01 pm
GNV
-
MYR
1 stop4h 54m
Delta
Mon 7/206:00 am
MYR
-
GNV
1 stop3h 28m
Delta
Deal found 6/9$403
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:41 pm
GNV
-
GSP
1 stop4h 34m
Delta
Mon 7/135:44 am
GSP
-
GNV
1 stop3h 44m
Delta
Deal found 6/10$407
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:41 pm
GNV
-
CLT
1 stop6h 16m
Delta
Wed 7/228:01 am
CLT
-
GNV
1 stop4h 22m
Delta
Deal found 6/8$413
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:04 pm
GNV
-
GSP
1 stop4h 55m
Delta
Sun 7/55:44 am
GSP
-
GNV
1 stop3h 46m
Delta
Deal found 6/10$417
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/179:48 am
GNV
-
MYR
1 stop5h 43m
American Airlines
Tue 7/216:10 pm
MYR
-
GNV
1 stop6h 06m
American Airlines
Deal found 6/9$422

Find flight deals from Gainesville to South Carolina

Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated June 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$357
(Delta)

One-way from

$268
(Delta)
Provider with most accurate pricing for Gainesville Regional-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Myrtle Beach Intl flights.
Search Deals
From Gainesville Regional to South Carolina
Search Deals
One-way flight from Gainesville Regional to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Thu 8/6

6:00 am-9:18 am

1 stop3h 18m

Greenville

Wed 8/12

5:46 am-9:23 am

1 stop3h 37m

$357

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Thu 7/16

7:01 pm-11:55 pm

1 stop4h 54m

Myrtle Beach Intl

Wed 7/22

11:42 am-2:56 pm

1 stop3h 14m

$357

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Thu 7/16

7:01 pm-11:55 pm

1 stop4h 54m

Myrtle Beach Intl

Tue 7/21

6:00 am-12:23 pm

1 stop6h 23m

$357

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Fri 7/17

6:33 am-1:00 pm

1 stop6h 27m

Myrtle Beach Intl

Wed 7/22

11:42 am-2:56 pm

1 stop3h 14m

$357

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Sat 7/18

5:33 pm-9:49 pm

1 stop4h 16m

Myrtle Beach Intl

Wed 7/22

11:42 am-2:56 pm

1 stop3h 14m

$357

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Sat 7/18

7:32 pm-11:51 pm

1 stop4h 19m

Greenville

Sat 7/25

7:30 pm-12:16 am

1 stop4h 46m

$367

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Wed 7/8

7:01 pm-11:54 pm

1 stop4h 53m

Greenville

Tue 7/14

6:45 am-12:23 pm

1 stop5h 38m

$367

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Fri 10/2

6:05 am-9:14 am

1 stop3h 09m

Greenville

Sun 10/4

5:45 am-9:21 am

1 stop3h 36m

$367

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Fri 7/17

7:01 pm-11:54 pm

1 stop4h 53m

Greenville

Sat 7/25

5:16 pm-9:46 pm

1 stop4h 30m

$367

GainesvilleMyrtle Beach

GNV - MYR

GNVMYR

Gainesville Regional

Sun 8/30

1:37 pm-6:07 pm

1 stop4h 30m

Myrtle Beach Intl

Sat 9/5

6:00 am-9:23 am

1 stop3h 23m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/8

Showing 1-10 of 46 resultsSorted by cheapest first
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Best time to book a flight from Gainesville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to South Carolina?

    If you book a flight to South Carolina from Gainesville, you will be flying from Gainesville Regional, which is the city’s only airport. Gainesville Regional (GNV) is located 4.2 mi from the center of Gainesville.

  • How long is the flight from Gainesville to South Carolina?

    Departing from Gainesville to South Carolina will take you 3h 18m. The distance between Gainesville and South Carolina is about 359 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to South Carolina?

    Most travelers choose Gainesville Regional - Charlotte Douglas, Gainesville Regional - Greenville or Gainesville Regional - Myrtle Beach Intl when deciding on the best route from Gainesville to South Carolina.

  • Can I find deals for flights from Gainesville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Gainesville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to South Carolina.

  • Can I find deals for business class flights from Gainesville to South Carolina?

    Yes. Cheapflights offers flight deals from Gainesville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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