$253+ Cheap flights from Gainesville (GNV) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
May 31 — Jun 71
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Gainesville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Gainesville to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Gainesville to South CarolinaExplore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:40 pm
GNV
- GSP
1 stop4h 33m
Delta
Sun 5/315:40 am
GSP
- GNV
1 stop3h 45m
Delta
Deal found 4/29![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:40 am
GNV
- CLT
Nonstop1h 45m
American Airlines
Tue 10/611:05 am
CLT
- GNV
Nonstop1h 51m
American Airlines
Deal found 4/28![American Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:13 am
GNV
- GSP
1 stop4h 02m
Delta
Sun 5/248:45 am
GSP
- GNV
1 stop3h 36m
Delta
Deal found 4/30![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:05 pm
GNV
- CLT
1 stop4h 52m
Delta
Tue 10/68:00 am
CLT
- GNV
1 stop4h 22m
Delta
Deal found 4/28![Delta logo]()
$393
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:48 am
GNV
- CLT
Nonstop1h 47m
American Airlines
Mon 6/110:50 pm
CLT
- GNV
Nonstop1h 43m
American Airlines
Deal found 4/29![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:59 pm
GNV
- GSP
1 stop3h 58m
American Airlines
Mon 6/17:32 pm
GSP
- GNV
1 stop5h 01m
American Airlines
Deal found 4/28![American Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:13 am
GNV
- CLT
1 stop3h 14m
Delta
Mon 6/112:05 pm
CLT
- GNV
1 stop6h 13m
Delta
Deal found 4/28![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:41 pm
GNV
- CLT
1 stop6h 16m
Delta
Sun 7/198:01 am
CLT
- GNV
1 stop4h 22m
Delta
Deal found 4/30![Delta logo]()
$434
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:58 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Sat 5/1612:59 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Deal found 4/27![American Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:05 pm
GNV
- MYR
1 stop4h 53m
Delta
Tue 5/1911:43 am
MYR
- GNV
1 stop6h 35m
Delta
Deal found 4/30![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 pm
GNV
- CLT
1 stop4h 48m
Delta
Sun 5/312:18 pm
CLT
- GNV
1 stop4h 00m
Delta
Deal found 4/28![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
GNV
- CLT
Nonstop1h 50m
American Airlines
Sat 5/305:14 pm
CLT
- GNV
Nonstop1h 46m
American Airlines
Deal found 4/28![American Airlines logo]()
$463
Best flights from Gainesville to South CarolinaDiscover carefully curated flight deals from Gainesville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Gainesville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:40 pm
GNV
- GSP
1 stop4h 33m
Delta
Sun 5/315:40 am
GSP
- GNV
1 stop3h 45m
Delta
Deal found 4/29![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:54 pm
GNV
- CLT
Nonstop1h 46m
American Airlines
Tue 10/610:30 pm
CLT
- GNV
Nonstop1h 46m
American Airlines
Deal found 4/26![American Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/209:48 am
GNV
- CLT
Nonstop1h 47m
American Airlines
Wed 6/2411:39 am
CLT
- GNV
Nonstop1h 45m
American Airlines
Deal found 4/30![American Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:13 am
GNV
- GSP
1 stop4h 02m
Delta
Sun 5/248:45 am
GSP
- GNV
1 stop3h 36m
Delta
Deal found 4/30![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
GNV
- CLT
1 stop6h 18m
American Airlines
Wed 9/92:35 pm
CLT
- GNV
Nonstop1h 47m
American Airlines
Deal found 4/26![American Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:00 am
GNV
- CLT
1 stop4h 32m
Delta
Wed 6/245:30 am
CLT
- GNV
1 stop4h 00m
Delta
Deal found 4/30![Delta logo]()
$393
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:05 pm
GNV
- CLT
1 stop4h 52m
Delta
Tue 10/68:00 am
CLT
- GNV
1 stop4h 22m
Delta
Deal found 4/28![Delta logo]()
$393
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:30 am
GNV
- CLT
1 stop4h 24m
American Airlines
Mon 6/14:40 pm
CLT
- GNV
1 stop7h 19m
American Airlines
Deal found 4/29![American Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:05 pm
GNV
- CLT
1 stop4h 48m
Delta
Mon 6/19:41 am
CLT
- GNV
1 stop5h 14m
Delta
Deal found 4/28![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:13 am
GNV
- CLT
1 stop6h 32m
Delta
Sun 5/316:59 am
CLT
- GNV
1 stop5h 23m
Delta
Deal found 4/28![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/191:49 pm
GNV
- MYR
1 stop6h 12m
American Airlines
Fri 6/266:50 am
MYR
- GNV
1 stop6h 34m
American Airlines
Deal found 5/1![American Airlines logo]()
$471
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:13 am
GNV
- CLT
1 stop3h 14m
Delta
Mon 6/18:01 am
CLT
- GNV
1 stop4h 21m
Delta
Deal found 4/28![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:32 pm
GNV
- GSP
1 stop4h 20m
American Airlines
Sun 6/147:32 pm
GSP
- GNV
1 stop5h 01m
American Airlines
Deal found 4/28![American Airlines logo]()
$483
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:41 pm
GNV
- CLT
1 stop6h 16m
Delta
Sun 7/198:01 am
CLT
- GNV
1 stop4h 22m
Delta
Deal found 4/30![Delta logo]()
$434
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:32 pm
GNV
- GSP
1 stop4h 20m
American Airlines
Sun 5/242:35 pm
GSP
- GNV
2 stops9h 24m
American Airlines
Deal found 4/30![American Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:05 pm
GNV
- MYR
1 stop4h 53m
Delta
Tue 5/1911:43 am
MYR
- GNV
1 stop6h 35m
Delta
Deal found 4/30![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:59 pm
GNV
- MYR
2 stops13h 59m
American Airlines
Tue 5/196:04 am
MYR
- GNV
1 stop5h 03m
American Airlines
Deal found 4/30![American Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:38 am
GNV
- MYR
1 stop6h 02m
Delta
Fri 5/1511:43 am
MYR
- GNV
1 stop6h 35m
Delta
Deal found 4/26![Delta logo]()
$635
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:59 pm
GNV
- MYR
2 stops13h 59m
American Airlines
Fri 5/154:09 pm
MYR
- GNV
1 stop6h 10m
American Airlines
Deal found 4/26![American Airlines logo]()
$997
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:30 pm
GNV
- GSP
1 stop6h 18m
Delta
Mon 5/258:45 am
GSP
- GNV
1 stop3h 37m
Delta
Deal found 4/29![Delta logo]()
$848
Last-minute flights from Gainesville to South CarolinaDiscover last-minute flight deals from Gainesville to South Carolina. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to South Carolina. Data last updated May 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:47 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Wed 5/63:35 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Deal found 4/27![American Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:58 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Sat 5/1612:59 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Deal found 4/27![American Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:05 pm
GNV
- MYR
1 stop4h 53m
Delta
Tue 5/1911:43 am
MYR
- GNV
1 stop6h 35m
Delta
Deal found 4/30![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:59 pm
GNV
- GSP
1 stop3h 58m
American Airlines
Mon 6/17:32 pm
GSP
- GNV
1 stop5h 01m
American Airlines
Deal found 4/28![American Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:13 am
GNV
- GSP
1 stop4h 02m
Delta
Sun 5/248:45 am
GSP
- GNV
1 stop3h 36m
Delta
Deal found 4/30![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:40 pm
GNV
- CLT
1 stop3h 19m
Delta
Mon 6/112:05 pm
CLT
- GNV
1 stop6h 13m
Delta
Deal found 4/28![Delta logo]()
$455
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:40 pm
GNV
- CLT
1 stop3h 19m
Delta
Sat 5/308:01 am
CLT
- GNV
1 stop4h 21m
Delta
Deal found 4/28![Delta logo]()
$393
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
GNV
- CLT
Nonstop1h 50m
American Airlines
Sat 5/305:14 pm
CLT
- GNV
Nonstop1h 46m
American Airlines
Deal found 4/28![American Airlines logo]()
$463
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:05 pm
GNV
- CLT
1 stop4h 48m
Delta
Mon 6/19:45 am
CLT
- GNV
2 stops12h 59m
Delta
Deal found 4/28![Delta logo]()
$484
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:40 pm
GNV
- GSP
1 stop4h 33m
Delta
Sun 5/315:40 am
GSP
- GNV
1 stop3h 45m
Delta
Deal found 4/29![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:48 am
GNV
- CLT
Nonstop1h 47m
American Airlines
Mon 6/110:50 pm
CLT
- GNV
Nonstop1h 43m
American Airlines
Deal found 4/29![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:13 am
GNV
- CLT
1 stop3h 14m
Delta
Mon 6/112:05 pm
CLT
- GNV
1 stop6h 13m
Delta
Deal found 4/28![Delta logo]()
$424
One-way flights from Gainesville to South CarolinaSearch for one-way flight options from Gainesville to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Gainesville to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:00 am
GNV
- CLT
Nonstop1h 50m
American Airlines
Deal found 4/27![American Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:11 pm
GNV
- MYR
1 stop5h 56m
Delta
Deal found 4/30![Delta logo]()
$268
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:30 am
GNV
- MYR
2 stops9h 02m
American Airlines
Deal found 4/30![American Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:36 pm
GNV
- CLT
2 stops15h 41m
Delta
Deal found 5/1![Delta logo]()
$288
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/263:47 pm
GNV
- CLT
2 stops17h 30m
Delta
Deal found 4/29![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:13 am
GNV
- MYR
1 stop5h 08m
Delta
Deal found 4/30![Delta logo]()
$318
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:05 pm
GNV
- CLT
2 stops15h 30m
Delta
Deal found 4/30![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:59 pm
GNV
- MYR
2 stops13h 59m
American Airlines
Deal found 4/30![American Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:33 pm
GNV
- CLT
2 stops15h 52m
Delta
Deal found 4/29![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:41 pm
GNV
- CLT
2 stops18h 54m
Delta
Deal found 4/29![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:05 pm
GNV
- CLT
2 stops17h 03m
Delta
Deal found 4/28![Delta logo]()
$371
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:11 pm
GNV
- MYR
1 stop5h 53m
Delta
Deal found 4/30![Delta logo]()
$388
Find flight deals from Gainesville to South Carolina
Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $367 (Delta) |
One-way from | $253 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Fri 5/29
3:40 pm-8:13 pm
1 stop4h 33m
Greenville
Sun 5/31
5:40 am-9:25 am
1 stop3h 45m
$367
Quickest round-trip
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Wed 9/30
1:54 pm-3:40 pm
Nonstop1h 46m
Charlotte Douglas
Tue 10/6
10:30 pm-12:16 am
Nonstop1h 46m
$373
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Sat 6/20
9:48 am-11:35 am
Nonstop1h 47m
Charlotte Douglas
Wed 6/24
11:39 am-1:24 pm
Nonstop1h 45m
$373
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Wed 8/19
6:00 am-12:18 pm
1 stop6h 18m
Charlotte Douglas
Wed 9/9
2:35 pm-4:22 pm
Nonstop1h 47m
$383
GainesvilleGreenville
GNV - GSP
GNVGSP
Gainesville Regional
Fri 5/22
10:13 am-2:15 pm
1 stop4h 02m
Greenville
Sun 5/24
8:45 am-12:21 pm
1 stop3h 36m
$387
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Sat 6/20
7:00 am-11:32 am
1 stop4h 32m
Charlotte Douglas
Wed 6/24
5:30 am-9:30 am
1 stop4h 00m
$393
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Wed 9/30
7:05 pm-11:57 pm
1 stop4h 52m
Charlotte Douglas
Tue 10/6
8:00 am-12:22 pm
1 stop4h 22m
$393
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Fri 5/29
6:30 am-10:54 am
1 stop4h 24m
Charlotte Douglas
Mon 6/1
4:40 pm-11:59 pm
1 stop7h 19m
$424
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Wed 5/27
7:05 pm-11:53 pm
1 stop4h 48m
Charlotte Douglas
Mon 6/1
9:41 am-2:55 pm
1 stop5h 14m
$424
GainesvilleCharlotte
GNV - CLT
GNVCLT
Gainesville Regional
Wed 5/27
10:13 am-4:45 pm
1 stop6h 32m
Charlotte Douglas
Sun 5/31
6:59 am-12:22 pm
1 stop5h 23m
$424
Showing 1-10 of 34 resultsSorted by cheapest first
Best time to book a flight from Gainesville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
GNV-GSP
GNV-CLT
GNV-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Gainesville to South Carolina
GNV-USSC
GNV-GSP
GNV-CLT
GNV-MYR
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 1, 2026.
Read through reviews of airlines operating flights from Gainesville to South Carolina, such as Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Gainesville to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Gainesville to South Carolina by cabin class
Find flights from Gainesville to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Gainesville and South Carolina flights
Browse other Gainesville and South Carolina flight options. Last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Gainesville to South Carolina flights
Consider these flights traveling from Gainesville to South Carolina.
Top airline flying from Gainesville to South Carolina
Discover the top airline that operate flights from Gainesville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$355 | Average$485 | FlexibilityNo cancel fee | On-timeN/A |