$294+ Cheap flights from South Carolina to Gainesville (GNV)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GNV
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Gainesville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Gainesville
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Cheapest flights from South Carolina to GainesvilleExplore the most affordable flight options available from South Carolina to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from South Carolina to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Tue 10/207:05 pm
GNV
- GSP
1 stop4h 32m
Delta
Deal found 4/28![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Thu 10/224:59 pm
GNV
- GSP
1 stop4h 22m
Delta
Deal found 4/28![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:45 am
GSP
- GNV
1 stop5h 36m
Delta
Sun 5/317:05 pm
GNV
- GSP
1 stop4h 38m
Delta
Deal found 4/26![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:10 am
CLT
- GNV
Nonstop1h 43m
American Airlines
Sun 10/256:35 am
GNV
- CLT
Nonstop1h 45m
American Airlines
Deal found 4/30![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Sun 10/254:59 pm
GNV
- GSP
1 stop4h 22m
Delta
Deal found 4/28![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:30 am
CLT
- GNV
1 stop3h 54m
Delta
Sun 10/256:00 am
GNV
- CLT
1 stop5h 04m
Delta
Deal found 4/28![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:35 pm
GSP
- GNV
2 stops9h 24m
American Airlines
Sat 5/307:32 pm
GNV
- GSP
1 stop4h 20m
American Airlines
Deal found 4/27![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:50 pm
CLT
- GNV
Nonstop1h 43m
American Airlines
Sun 6/217:32 pm
GNV
- CLT
Nonstop1h 52m
American Airlines
Deal found 4/30![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:20 am
CLT
- GNV
Nonstop1h 42m
American Airlines
Thu 6/181:49 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Deal found 4/27![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:59 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Tue 6/91:49 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Deal found 4/30![American Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:40 am
GSP
- GNV
1 stop3h 45m
Delta
Tue 5/191:11 pm
GNV
- GSP
1 stop5h 42m
Delta
Deal found 4/30![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:45 pm
GSP
- GNV
1 stop5h 14m
American Airlines
Tue 5/196:25 am
GNV
- GSP
2 stops10h 25m
American Airlines
Deal found 4/30![American Airlines logo]()
$452
Best flights from South Carolina to GainesvilleDiscover carefully curated flight deals from South Carolina to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from South Carolina to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Sat 10/2410:20 am
GNV
- GSP
1 stop4h 29m
Delta
Deal found 4/28![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:35 pm
CLT
- GNV
Nonstop1h 46m
American Airlines
Sun 10/2510:41 am
GNV
- CLT
Nonstop1h 44m
American Airlines
Deal found 4/27![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Mon 10/194:59 pm
GNV
- GSP
1 stop3h 15m
Delta
Deal found 4/28![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:45 am
GSP
- GNV
1 stop5h 36m
Delta
Sun 5/317:05 pm
GNV
- GSP
1 stop4h 38m
Delta
Deal found 4/26![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:35 pm
GSP
- GNV
2 stops9h 24m
American Airlines
Sat 5/307:32 pm
GNV
- GSP
1 stop4h 20m
American Airlines
Deal found 4/27![American Airlines logo]()
$430
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Sun 10/254:59 pm
GNV
- GSP
1 stop4h 22m
Delta
Deal found 4/28![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:15 am
GSP
- GNV
1 stop3h 47m
American Airlines
Sun 5/317:32 pm
GNV
- GSP
1 stop4h 20m
American Airlines
Deal found 4/26![American Airlines logo]()
$501
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:41 am
CLT
- GNV
1 stop5h 14m
Delta
Tue 6/27:05 pm
GNV
- CLT
1 stop4h 48m
Delta
Deal found 4/28![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am
CLT
- GNV
1 stop3h 54m
Delta
Sat 10/3110:20 am
GNV
- CLT
1 stop5h 44m
Delta
Deal found 4/27![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:01 am
CLT
- GNV
1 stop4h 24m
Delta
Mon 6/157:04 pm
GNV
- CLT
1 stop4h 55m
Delta
Deal found 4/27![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:45 am
CLT
- GNV
1 stop5h 37m
Delta
Sun 10/256:00 am
GNV
- CLT
1 stop5h 04m
Delta
Deal found 4/30![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:41 am
CLT
- GNV
1 stop5h 14m
Delta
Tue 6/910:17 am
GNV
- CLT
1 stop3h 18m
Delta
Deal found 4/29![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:40 am
GSP
- GNV
1 stop3h 45m
Delta
Tue 5/191:11 pm
GNV
- GSP
1 stop5h 42m
Delta
Deal found 4/30![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am
GSP
- GNV
1 stop3h 44m
Delta
Fri 10/2310:20 am
GNV
- GSP
2 stops11h 56m
Delta
Deal found 4/28![Delta logo]()
$562
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:05 pm
GSP
- GNV
1 stop5h 39m
Delta
Fri 5/156:38 am
GNV
- GSP
1 stop5h 27m
Delta
Deal found 4/27![Delta logo]()
$635
Last-minute flights from South Carolina to GainesvilleDiscover last-minute flight deals from South Carolina to Gainesville. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Gainesville. Data last updated May 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:51 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Sat 5/96:00 am
GNV
- CLT
1 stop6h 58m
American Airlines
Deal found 5/1![American Airlines logo]()
$465
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:35 pm
CLT
- GNV
Nonstop1h 44m
American Airlines
Sun 5/36:30 am
GNV
- CLT
Nonstop1h 50m
American Airlines
Deal found 4/28![American Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:51 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Sat 5/93:07 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Deal found 4/30![American Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:30 am
CLT
- GNV
1 stop3h 54m
Delta
Sat 5/910:13 am
GNV
- CLT
1 stop3h 14m
Delta
Deal found 4/27![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:59 pm
CLT
- GNV
Nonstop1h 42m
American Airlines
Tue 6/91:49 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Deal found 4/30![American Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:01 am
CLT
- GNV
1 stop4h 21m
Delta
Tue 6/93:47 pm
GNV
- CLT
1 stop6h 13m
Delta
Deal found 4/30![Delta logo]()
$460
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:40 am
GSP
- GNV
1 stop3h 45m
Delta
Tue 5/191:11 pm
GNV
- GSP
1 stop5h 42m
Delta
Deal found 4/30![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:45 pm
GSP
- GNV
1 stop5h 14m
American Airlines
Tue 5/196:25 am
GNV
- GSP
2 stops10h 25m
American Airlines
Deal found 4/30![American Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:45 am
GSP
- GNV
1 stop5h 36m
Delta
Sun 5/317:05 pm
GNV
- GSP
1 stop4h 38m
Delta
Deal found 4/26![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:14 pm
CLT
- GNV
Nonstop1h 46m
American Airlines
Tue 6/21:49 pm
GNV
- CLT
Nonstop1h 48m
American Airlines
Deal found 4/28![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:41 am
CLT
- GNV
1 stop5h 14m
Delta
Tue 6/27:05 pm
GNV
- CLT
1 stop4h 48m
Delta
Deal found 4/28![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:32 pm
GSP
- GNV
1 stop5h 01m
American Airlines
Sat 5/306:30 am
GNV
- GSP
1 stop5h 12m
American Airlines
Deal found 4/27![American Airlines logo]()
$367
One-way flights from South Carolina to GainesvilleSearch for one-way flight options from South Carolina to Gainesville. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from South Carolina to Gainesville. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:00 pm
CLT
- GNV
2 stops19h 21m
Delta
Deal found 4/29![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:00 pm
CLT
- GNV
2 stops19h 22m
Delta
Deal found 5/1![Delta logo]()
$320
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:50 pm
CLT
- GNV
2 stops19h 33m
Delta
Deal found 4/27![Delta logo]()
$350
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:03 pm
CLT
- GNV
2 stops16h 27m
Delta
Deal found 4/27![Delta logo]()
$371
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:20 am
CLT
- GNV
Nonstop1h 42m
American Airlines
Deal found 4/29![American Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:05 pm
CLT
- GNV
1 stop6h 13m
Delta
Deal found 4/27![Delta logo]()
$423
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:20 am
CLT
- GNV
Nonstop1h 42m
American Airlines
Deal found 4/30![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:10 am
CLT
- GNV
Nonstop1h 47m
American Airlines
Deal found 4/28![American Airlines logo]()
$456
Find flight deals from South Carolina to Gainesville
Keep the following information in mind while searching for South Carolina to Gainesville flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $357 (Delta) |
One-way from | $294 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from South Carolina to Gainesville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleGainesville
GSP - GNV
GSPGNV
Greenville
Fri 10/16
5:40 am-9:24 am
1 stop3h 44m
Gainesville Regional
Sat 10/24
10:20 am-2:49 pm
1 stop4h 29m
$367
GreenvilleGainesville
GSP - GNV
GSPGNV
Greenville
Fri 10/16
5:40 am-9:24 am
1 stop3h 44m
Gainesville Regional
Mon 10/19
4:59 pm-8:14 pm
1 stop3h 15m
$367
GreenvilleGainesville
GSP - GNV
GSPGNV
Greenville
Sun 5/24
6:45 am-12:21 pm
1 stop5h 36m
Gainesville Regional
Sun 5/31
7:05 pm-11:43 pm
1 stop4h 38m
$377
Quickest round-trip
CharlotteGainesville
CLT - GNV
CLTGNV
Charlotte Douglas
Sat 10/17
2:35 pm-4:21 pm
Nonstop1h 46m
Gainesville Regional
Sun 10/25
10:41 am-12:25 pm
Nonstop1h 44m
$404
GreenvilleGainesville
GSP - GNV
GSPGNV
Greenville
Fri 10/16
5:40 am-9:24 am
1 stop3h 44m
Gainesville Regional
Sun 10/25
4:59 pm-9:21 pm
1 stop4h 22m
$407
CharlotteGainesville
CLT - GNV
CLTGNV
Charlotte Douglas
Tue 5/26
9:41 am-2:55 pm
1 stop5h 14m
Gainesville Regional
Tue 6/2
7:05 pm-11:53 pm
1 stop4h 48m
$424
CharlotteGainesville
CLT - GNV
CLTGNV
Charlotte Douglas
Thu 10/22
5:30 am-9:24 am
1 stop3h 54m
Gainesville Regional
Sat 10/31
10:20 am-4:04 pm
1 stop5h 44m
$424
CharlotteGainesville
CLT - GNV
CLTGNV
Charlotte Douglas
Wed 6/10
8:01 am-12:25 pm
1 stop4h 24m
Gainesville Regional
Mon 6/15
7:04 pm-11:59 pm
1 stop4h 55m
$424
CharlotteGainesville
CLT - GNV
CLTGNV
Charlotte Douglas
Sat 10/17
6:45 am-12:22 pm
1 stop5h 37m
Gainesville Regional
Sun 10/25
6:00 am-11:04 am
1 stop5h 04m
$424
CharlotteGainesville
CLT - GNV
CLTGNV
Charlotte Douglas
Thu 6/4
9:41 am-2:55 pm
1 stop5h 14m
Gainesville Regional
Tue 6/9
10:17 am-1:35 pm
1 stop3h 18m
$424
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Gainesville
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CLT-GNV
GSP-GNV
Estimated round-trip price
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Cheapflights Insights
Everything you need to know about your flight from South Carolina to Gainesville
USSC-GNV
CLT-GNV
GSP-GNV
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Traveling to a place near Gainesville?
Book flights to Gainesville if you plan to visit one of these locationsLake City
Alachua
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Top airline flying from South Carolina to Gainesville
Discover the top airline that operate flights from South Carolina to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$476 | FlexibilityNo cancel fee | On-timeN/A |