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Greenville

$440+ Cheap flights from St. Louis to Greenville, NC (STL - PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PGV
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from St. Louis to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (PGV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$440
(American Airlines)
From Lambert-St Louis to Pitt-Greenville
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Find flight deals from St. Louis to Greenville

Cheapest flights from St. Louis to Greenville
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:22 amSTL - PGV
1 stop4h 16mAmerican Airlines
Sun 10/125:00 amPGV - STL
1 stop4h 16mAmerican Airlines
Deal found 9/14$440
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:45 pmSTL - PGV
1 stop4h 14mAmerican Airlines
Sat 11/295:03 amPGV - STL
1 stop4h 24mAmerican Airlines
Deal found 9/16$499
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:43 pmSTL - PGV
2 stops7h 16mAmerican Airlines
Sat 11/295:03 amPGV - STL
1 stop4h 24mAmerican Airlines
Deal found 9/15$504
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:57 amSTL - PGV
1 stop5h 45mAmerican Airlines
Sun 10/56:00 amPGV - STL
1 stop6h 57mAmerican Airlines
Deal found 9/15$529
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:00 amSTL - PGV
1 stop4h 31mAmerican Airlines
Sun 11/305:03 amPGV - STL
1 stop4h 24mAmerican Airlines
Deal found 9/15$622
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:00 amSTL - PGV
2 stops27h 31mAmerican Airlines
Sun 11/305:56 pmPGV - STL
1 stop7h 09mAmerican Airlines
Deal found 9/15$665

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.

Fly from

St. Louis

Fly to

Greenville

Route

Depart

Return

Price

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Tue 10/7

10:22 am-3:38 pm

1 stop4h 16m

Pitt-Greenville

Sun 10/12

5:00 am-8:16 am

1 stop4h 16m

$440

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Wed 11/26

6:45 pm-11:59 pm

1 stop4h 14m

Pitt-Greenville

Sat 11/29

5:03 am-8:27 am

1 stop4h 24m

$499

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Tue 11/25

6:45 pm-11:59 pm

1 stop4h 14m

Pitt-Greenville

Sat 11/29

5:03 am-8:27 am

1 stop4h 24m

$499

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Fri 10/3

9:57 am-4:42 pm

1 stop5h 45m

Pitt-Greenville

Sun 10/5

6:00 am-11:57 am

1 stop6h 57m

$529

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from St. Louis to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Greenville

What is the cheapest month to book a flight from St. Louis to Greenville, North Carolina?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Greenville, North Carolina (average of $302). Flying from St. Louis to Greenville, North Carolina in June is currently the most expensive (average of $434). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Greenville, North Carolina?

    For as low as $440, American Airlines can have you in Greenville, North Carolina from St. Louis in 4h 16m. The distance between St. Louis and Greenville, North Carolina is about 745 mi.

  • Can I find deals for flights from St. Louis to Greenville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Greenville.

  • Can I find deals for business class flights from St. Louis to Greenville?

    Yes. Cheapflights offers flight deals from St. Louis to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Greenville, North Carolina?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Greenville, North Carolina (average of $302). Flying from St. Louis to Greenville, North Carolina in June is currently the most expensive (average of $434). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Williamston

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