HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$439+ Cheap flights from St. Louis to Greenville, NC (STL - PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PGV
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (PGV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$439
(American Airlines)
Provider with most accurate pricing for Lambert-St Louis-Pitt-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Pitt-Greenville flights.
Search Deals
From Lambert-St Louis to Pitt-Greenville
Search Deals

Find flight deals from St. Louis to Greenville

Cheapest flights from St. Louis to Greenville
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:00 amSTL - PGV
1 stop4h 36mAmerican Airlines
Mon 12/295:03 amPGV - STL
1 stop4h 32mAmerican Airlines
Deal found 11/20$439
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:02 amSTL - PGV
1 stop4h 31mAmerican Airlines
Tue 12/166:00 amPGV - STL
1 stop4h 32mAmerican Airlines
Deal found 11/18$510
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:52 amSTL - PGV
1 stop4h 20mAmerican Airlines
Tue 12/91:00 pmPGV - STL
2 stops11h 59mAmerican Airlines
Deal found 11/20$524

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.

Fly from

St. Louis

Fly to

Greenville

Route

Depart

Return

Price

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Sat 12/27

5:00 am-10:36 am

1 stop4h 36m

Pitt-Greenville

Mon 12/29

5:03 am-8:35 am

1 stop4h 32m

$439

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Sat 12/13

5:02 am-10:33 am

1 stop4h 31m

Pitt-Greenville

Tue 12/16

6:00 am-9:32 am

1 stop4h 32m

$510

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Fri 12/5

2:04 pm-6:51 pm

1 stop3h 47m

Pitt-Greenville

Tue 12/9

6:00 am-9:32 am

1 stop4h 32m

$526

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Compare providers for flights from St. Louis to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Greenville, North Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Greenville, North Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Greenville, North Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Greenville, North Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Greenville, North Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Greenville

What is the cheapest month to book a flight from St. Louis to Greenville, North Carolina?

Currently, October is the cheapest month in which you can book a flight from St. Louis to Greenville, North Carolina (average of $144). Flying from St. Louis to Greenville, North Carolina in May is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Greenville, North Carolina?

    For as low as $439, American Airlines can have you in Greenville, North Carolina from St. Louis in 4h 36m. The distance between St. Louis and Greenville, North Carolina is about 745 mi.

  • Can I find deals for flights from St. Louis to Greenville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Greenville.

  • Can I find deals for business class flights from St. Louis to Greenville?

    Yes. Cheapflights offers flight deals from St. Louis to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Greenville, North Carolina?

    Currently, October is the cheapest month in which you can book a flight from St. Louis to Greenville, North Carolina (average of $144). Flying from St. Louis to Greenville, North Carolina in May is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Williamston

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Charlotte flights
St. Louis to Raleigh flights
St. Louis to Knoxville flights
Kansas City to Raleigh flights
Kansas City to Charlotte flights
St. Louis to Myrtle Beach flights
St. Louis to Asheville flights
Kansas City to Norfolk flights
Kansas City to Greensboro flights
St. Louis to Norfolk flights
Springfield to Raleigh flights
Kansas City to Knoxville flights
Springfield to Norfolk flights
Kansas City to Myrtle Beach flights
St. Louis to Greensboro flights
St. Louis to Wilmington flights
Springfield to Charlotte flights
Kansas City to Asheville flights
Springfield to Knoxville flights
Springfield to Greensboro flights
Springfield to Myrtle Beach flights
Joplin to Raleigh flights
Springfield to Fayetteville flights
Springfield to Asheville flights
St. Louis to Fayetteville flights
Kansas City to Wilmington flights
Kansas City to Fayetteville flights
Kansas City to Blountville flights
St. Louis to Blountville flights
Columbia to Knoxville flights
Springfield to Wilmington flights
St. Louis to Jacksonville flights
Columbia to Charlotte flights
Kansas City to Jacksonville flights
Joplin to Charlotte flights
Columbia to Myrtle Beach flights
Cape Girardeau to Charlotte flights
Columbia to Norfolk flights
St. Louis to New Bern flights
Kansas City to New Bern flights
Kansas City to Greenville flights
Columbia to Asheville flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.