$296+ Cheap flights from Greenville, NC to St. Louis (PGV - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — STL
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to St. LouisExplore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:05 am -
1 stop4h 32m
Sat 10/174:21 pm -
1 stop6h 35m
Deal found 9/2![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:11 pm -
1 stop6h 19m
Wed 9/238:43 am -
1 stop7h 09m
Deal found 9/4![American Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:18 pm -
1 stop6h 24m
Sun 9/205:15 am -
1 stop4h 21m
Deal found 9/3![American Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:15 pm -
1 stop6h 40m
Thu 9/106:53 am -
1 stop3h 47m
Deal found 8/31![American Airlines logo]()
$821
Best flights from Greenville to St. LouisDiscover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:20 pm -
1 stop7h 23m
Sat 10/175:00 am -
1 stop4h 32m
Deal found 9/1![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:05 am -
1 stop4h 32m
Sat 10/174:21 pm -
1 stop6h 35m
Deal found 9/2![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:11 pm -
1 stop6h 19m
Wed 9/238:43 am -
1 stop7h 09m
Deal found 9/4![American Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:18 pm -
1 stop6h 24m
Sun 9/205:15 am -
1 stop4h 21m
Deal found 9/3![American Airlines logo]()
$591
Last-minute flights from Greenville to St. LouisDiscover last-minute flight deals from Greenville to St. Louis. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to St. Louis. Data last updated September 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:15 pm -
1 stop6h 40m
Thu 9/106:53 am -
1 stop3h 47m
Deal found 8/31![American Airlines logo]()
$821
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:18 pm -
1 stop6h 24m
Sun 9/205:15 am -
1 stop4h 21m
Deal found 9/3![American Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:11 pm -
1 stop6h 19m
Wed 9/238:43 am -
1 stop7h 09m
Deal found 9/4![American Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:05 am -
1 stop4h 32m
Sat 10/174:21 pm -
1 stop6h 35m
Deal found 9/2![American Airlines logo]()
$463
One-way flights from Greenville to St. LouisSearch for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
Search for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:11 pm -
1 stop6h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$296
Find flight deals from Greenville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $463 (American Airlines) |
One-way from | $296 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSt. Louis
PGV Pitt-Greenville - STL Lambert-St Louis
PGVSTL
Pitt-Greenville
Sat 9/19
12:11 pm-5:30 pm
1 stop6h 19m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$296
GreenvilleSt. Louis
PGV Pitt-Greenville - STL Lambert-St Louis
PGVSTL
Pitt-Greenville
Tue 10/13
12:20 pm-6:43 pm
1 stop7h 23m
Lambert-St Louis
Sat 10/17
5:00 am-10:32 am
1 stop4h 32m
$463
GreenvilleSt. Louis
PGV Pitt-Greenville - STL Lambert-St Louis
PGVSTL
Pitt-Greenville
Wed 10/14
5:05 am-8:37 am
1 stop4h 32m
Lambert-St Louis
Sat 10/17
4:21 pm-11:56 pm
1 stop6h 35m
$463
GreenvilleSt. Louis
PGV Pitt-Greenville - STL Lambert-St Louis
PGVSTL
Pitt-Greenville
Sat 9/19
12:11 pm-5:30 pm
1 stop6h 19m
Lambert-St Louis
Wed 9/23
8:43 am-4:52 pm
1 stop7h 09m
$561
GreenvilleSt. Louis
PGV Pitt-Greenville - STL Lambert-St Louis
PGVSTL
Pitt-Greenville
Fri 9/18
5:18 pm-10:42 pm
1 stop6h 24m
Lambert-St Louis
Sun 9/20
5:15 am-10:36 am
1 stop4h 21m
$591
Sorted by cheapest first
Compare providers for flights from Greenville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville, North Carolina-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville, North Carolina-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville, North Carolina-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville, North Carolina-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville, North Carolina-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
PGV-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
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