$173+ Cheap flights from San Francisco to Greenville (SFO - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Feb 28 — Mar 71
1 adult, Economy
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Find cheap flights from San Francisco to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Greenville
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Best
Last-minute
One-way
Cheapest flights from San Francisco to GreenvilleExplore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:55 am
SFO
- GSP
2 stops8h 50m
Southwest
Wed 4/81:55 pm
GSP
- SFO
2 stops11h 15m
Southwest
Deal found 1/26![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:00 am
SFO
- GSP
1 stop7h 36m
United Airlines
Thu 2/196:12 am
GSP
- SFO
1 stop10h 26m
United Airlines
Deal found 1/28![United Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:30 am
SFO
- GSP
2 stops9h 45m
American Airlines
Thu 2/192:19 pm
GSP
- SFO
1 stop9h 37m
American Airlines
Deal found 1/28![American Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:29 pm
SFO
- GSP
1 stop8h 27m
American Airlines
Wed 4/85:12 pm
GSP
- SFO
1 stop7h 45m
American Airlines
Deal found 1/26![American Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:30 pm
SFO
- GSP
1 stop9h 40m
Southwest
Mon 3/28:20 am
GSP
- SFO
2 stops12h 20m
Southwest
Deal found 1/27![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:25 am
SFO
- GSP
1 stop6h 50m
American Airlines
Mon 2/234:26 pm
GSP
- SFO
1 stop9h 44m
American Airlines
Deal found 1/29![American Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:00 am
SFO
- GSP
1 stop7h 37m
Delta
Sun 3/87:59 pm
GSP
- SFO
1 stop7h 36m
Delta
Deal found 1/28![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:36 am
SFO
- GSP
1 stop10h 06m
American Airlines
Mon 3/24:26 pm
GSP
- SFO
1 stop9h 44m
American Airlines
Deal found 1/27![American Airlines logo]()
$409
Best flights from San Francisco to GreenvilleDiscover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 29, 2026.
Discover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 29, 2026.
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:55 am
SFO
- GSP
2 stops8h 50m
Southwest
Wed 4/81:55 pm
GSP
- SFO
2 stops11h 15m
Southwest
Deal found 1/26![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:00 am
SFO
- GSP
1 stop7h 36m
United Airlines
Thu 2/196:12 am
GSP
- SFO
1 stop10h 26m
United Airlines
Deal found 1/28![United Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:30 am
SFO
- GSP
2 stops9h 45m
American Airlines
Thu 2/192:19 pm
GSP
- SFO
1 stop9h 37m
American Airlines
Deal found 1/28![American Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:00 am
SFO
- GSP
1 stop7h 37m
Delta
Sun 3/87:59 pm
GSP
- SFO
1 stop7h 36m
Delta
Deal found 1/28![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:29 pm
SFO
- GSP
1 stop8h 27m
American Airlines
Wed 4/85:12 pm
GSP
- SFO
1 stop7h 45m
American Airlines
Deal found 1/26![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:52 pm
SFO
- GSP
1 stop7h 04m
United Airlines
Sat 5/26:36 am
GSP
- SFO
1 stop9h 47m
United Airlines
Deal found 1/27![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/268:25 am
SFO
- GSP
2 stops10h 20m
Southwest
Mon 3/28:20 am
GSP
- SFO
2 stops12h 20m
Southwest
Deal found 1/27![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:52 pm
SFO
- GSP
1 stop7h 04m
United Airlines
Fri 5/16:36 am
GSP
- SFO
1 stop7h 48m
United Airlines
Deal found 1/29![United Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:30 pm
SFO
- GSP
1 stop8h 26m
American Airlines
Sun 3/82:13 pm
GSP
- SFO
1 stop9h 43m
American Airlines
Deal found 1/27![American Airlines logo]()
$407
Last-minute flights from San Francisco to GreenvilleDiscover last-minute flight deals from San Francisco to Greenville. Data last updated January 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Greenville. Data last updated January 29, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/119:30 pm
SFO
- GSP
1 stop9h 40m
Southwest
Sun 2/1510:45 am
GSP
- SFO
1 stop8h 00m
Southwest
Deal found 1/27![Southwest logo]()
$439
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:30 am
SFO
- GSP
2 stops9h 45m
American Airlines
Thu 2/192:19 pm
GSP
- SFO
1 stop9h 37m
American Airlines
Deal found 1/28![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:00 am
SFO
- GSP
1 stop7h 36m
United Airlines
Thu 2/196:12 am
GSP
- SFO
1 stop10h 26m
United Airlines
Deal found 1/28![United Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:25 am
SFO
- GSP
1 stop6h 50m
American Airlines
Mon 2/234:26 pm
GSP
- SFO
1 stop9h 44m
American Airlines
Deal found 1/29![American Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:05 am
SFO
- GSP
2 stops10h 45m
Southwest
Thu 2/1910:45 am
GSP
- SFO
2 stops12h 30m
Southwest
Deal found 1/28![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:30 pm
SFO
- GSP
1 stop9h 40m
Southwest
Mon 2/2312:30 pm
GSP
- SFO
2 stops12h 45m
Southwest
Deal found 1/29![Southwest logo]()
$421
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:05 pm
SFO
- GSP
1 stop6h 38m
Delta
Sun 3/15:40 am
GSP
- SFO
1 stop10h 10m
Delta
Deal found 1/29![Delta logo]()
$433
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:30 pm
SFO
- GSP
1 stop9h 40m
Southwest
Mon 3/28:20 am
GSP
- SFO
2 stops12h 20m
Southwest
Deal found 1/27![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:36 am
SFO
- GSP
1 stop10h 06m
American Airlines
Mon 3/24:26 pm
GSP
- SFO
1 stop9h 44m
American Airlines
Deal found 1/27![American Airlines logo]()
$409
One-way flights from San Francisco to GreenvilleSearch for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated January 29, 2026.
Search for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated January 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:31 pm
SFO
- GSP
3 stops46h 22m
Multiple Airlines
Deal found 1/27![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:40 pm
SFO
- GSP
2 stops15h 35m
Multiple Airlines
Deal found 1/29![Multiple Airlines logo]()
$182
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:59 pm
SFO
- GSP
1 stop7h 02m
United Airlines
Deal found 1/28![United Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:32 pm
SFO
- GSP
3 stops41h 14m
Multiple Airlines
Deal found 1/26![Multiple Airlines logo]()
$185
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:35 am
SFO
- GSP
2 stops10h 05m
Southwest
Deal found 1/26![Southwest logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:09 pm
SFO
- GSP
2 stops14h 44m
Multiple Airlines
Deal found 1/27![Multiple Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:35 pm
SFO
- GSP
1 stop8h 26m
American Airlines
Deal found 1/27![American Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:25 pm
SFO
- GSP
2 stops10h 45m
Southwest
Deal found 1/27![Southwest logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:55 am
SFO
- GSP
3 stops27h 17m
Multiple Airlines
Deal found 1/28![Multiple Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/119:30 pm
SFO
- GSP
1 stop9h 40m
Southwest
Deal found 1/28![Southwest logo]()
$220
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/159:20 pm
SFO
- GSP
1 stop13h 00m
Southwest
Deal found 1/29![Southwest logo]()
$229
Find flight deals from San Francisco to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $377 (Southwest) |
One-way from | $173 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $415 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.
Fly from
San Francisco
Fly to
Greenville
Route
Depart
Return
Price
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 4/1
5:55 am-5:45 pm
2 stops8h 50m
Greenville
Wed 4/8
1:55 pm-10:10 pm
2 stops11h 15m
$377
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 2/18
5:00 am-3:36 pm
1 stop7h 36m
Greenville
Thu 2/19
6:12 am-1:38 pm
1 stop10h 26m
$380
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Tue 2/17
12:30 am-1:15 pm
2 stops9h 45m
Greenville
Thu 2/19
2:19 pm-8:56 pm
1 stop9h 37m
$392
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 4/1
11:29 pm-10:56 am
1 stop8h 27m
Greenville
Wed 4/8
5:12 pm-9:57 pm
1 stop7h 45m
$393
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 4/25
11:52 pm-9:56 am
1 stop7h 04m
Greenville
Sat 5/2
6:36 am-1:23 pm
1 stop9h 47m
$393
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Thu 2/26
8:25 am-9:45 pm
2 stops10h 20m
Greenville
Mon 3/2
8:20 am-5:40 pm
2 stops12h 20m
$403
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Tue 3/3
8:00 am-6:37 pm
1 stop7h 37m
Greenville
Sun 3/8
7:59 pm-12:35 am
1 stop7h 36m
$407
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Tue 4/28
11:52 pm-9:56 am
1 stop7h 04m
Greenville
Fri 5/1
6:36 am-11:24 am
1 stop7h 48m
$407
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Tue 3/3
11:30 pm-10:56 am
1 stop8h 26m
Greenville
Sun 3/8
2:13 pm-8:56 pm
1 stop9h 43m
$407
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sun 3/15
10:40 pm-5:15 pm
2 stops15h 35m
$182
Showing 1-10 of 20 results
Compare providers for flights from San Francisco to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in January.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
SFO-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Greenville
How far ahead should I book a flight from San Francisco to Greenville?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Greenville. Price data was last updated on January 23, 2026.
To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from San Francisco to Greenville?
Currently, April is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $167). Flying from San Francisco to Greenville in December is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsSimpsonville
Duncan
Greer
Seneca
Anderson
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Alternative routes for San Francisco to Greenville
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Top 4 airlines flying from San Francisco to Greenville
Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$447 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$498 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$313 | Average$434 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$424 | Average$576 | FlexibilityNo cancel fee | On-time69% |