Greenville

$157+ Cheap flights from San Francisco to Greenville (SFO - GSP)

SFO — GSP
Dec 10 — Dec 171
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1. Tell us where you want to go

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Cheap flight deals from San Francisco to Greenville

Cheapest flights from San Francisco to Greenville

Wed 12/1611:59 pm -
1 stop6h 41m
Tue 1/58:01 am -
1 stop7h 41m
Deal found 11/5$405
Fri 12/1112:10 pm -
1 stop7h 50m
Tue 12/2210:25 am -
1 stop12h 45m
Deal found 11/4$429
Fri 12/1111:59 pm -
1 stop8h 35m
Mon 12/142:04 pm -
1 stop8h 21m
Deal found 11/9$433
Fri 12/119:40 am -
2 stops10h 20m
Mon 12/148:05 am -
1 stop8h 45m
Deal found 11/9$438
Sat 12/125:00 am -
1 stop8h 45m
Wed 12/235:22 pm -
1 stop9h 04m
Deal found 11/4$460
Thu 12/105:35 am -
1 stop7h 48m
Sun 12/135:17 pm -
1 stop8h 14m
Deal found 11/7$465
Thu 12/107:15 am -
2 stops10h 35m
Sun 12/138:15 am -
1 stop8h 30m
Deal found 11/7$470
Fri 12/1112:10 pm -
1 stop7h 50m
Sun 12/136:40 am -
2 stops9h 25m
Deal found 11/7$480
Fri 12/115:00 am -
1 stop7h 21m
Tue 12/222:28 pm -
1 stop10h 19m
Deal found 11/5$484

Find flight deals from San Francisco to Greenville

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$388
(United Airlines)

One-way from

$157
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$582
Provider with most accurate pricing for San Francisco-Greenville flight deals.
Provider most trusted by Cheapflights users for San Francisco-Greenville flights.
From San Francisco to Greenville
One-way flight from San Francisco to Greenville
Highest demand for flights based on searches. 13% potential increase in price ($81 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Thu 12/17

10:34 pm-9:28 am

1 stop7h 54m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$185

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 12/16

10:40 pm-10:12 am

1 stop8h 32m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$185

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 12/9

6:10 am-6:10 pm

2 stops9h 00m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$190

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 12/16

7:26 pm-7:59 pm

2 stops21h 33m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$198

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Thu 12/17

10:40 am-11:00 pm

2 stops9h 20m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$198

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 11/18

10:20 pm-8:13 am

2 stops30h 53m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$217

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 12/29

6:00 pm-7:53 am

3 stops34h 53m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$221

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 12/29

9:25 pm-10:00 am

1 stop9h 35m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$240

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 12/30

12:53 am-7:59 pm

2 stops16h 06m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$242

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Thu 11/26

9:11 pm-7:54 am

3 stops31h 43m

Greenville

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from San Francisco to Greenville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Greenville

What is the cheapest month to book a flight from San Francisco to Greenville?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $393). Flying from San Francisco to Greenville in May is currently the most expensive (average of $698). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Francisco to Greenville?

Airfare is below average for this route at the moment.

San Francisco to Greenville flights typically cost between $537 and $637 in December.
The cheapest round-trip price found within the last 5 days was $388 on United Airlines (Dec 1-Dec 2).

Reviews of airlines servicing Greenville

See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Boarding

8.1

Entertainment

7.4

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Boarding

8.1

Entertainment

7.4

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Boarding

8.1

Entertainment

7.4

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Boarding

8.1

Entertainment

7.4

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Boarding

8.1

Entertainment

7.4

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Related info for your journey

  • How long is the flight from San Francisco to Greenville?

    Southwest and American Airlines can get you from San Francisco to Greenville in just under 7h 50m. Your travel time can differ by up to 55m. San Francisco and Greenville are separated by a distance of 2227 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Francisco to Greenville round-trip?

    Cheapflights users have booked flights from San Francisco to Greenville round-trip from $336. Other airlines that can offer you cheap pricing are American Airlines, from $339, and Southwest, from $363. Delta is currently priced 36% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from San Francisco to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $116. American Airlines flights start at $181 while deals on Southwest start at $189 one-way.

  • Can I find deals for flights from San Francisco to Greenville that include hotel bookings?

    Yes. In addition to deals on San Francisco to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Greenville.

  • Can I find deals for business class flights from San Francisco to Greenville?

    Yes. Cheapflights offers flight deals from San Francisco to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Greenville?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $393). Flying from San Francisco to Greenville in May is currently the most expensive (average of $698). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Anderson
Seneca

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for San Francisco to Greenville

Top 4 airlines flying from San Francisco to Greenville

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$336Average$573FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$339Average$547FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$363Average$478FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$424Average$511FlexibilityNo cancel feeOn-time69%

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