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Greenville

$146+ Cheap flights from San Francisco to Greenville (SFO - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from San Francisco to Greenville

Cheapest flights from San Francisco to Greenville
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:25 am
SFO
-
GSP
1 stop6h 50m
American Airlines
Thu 4/95:12 pm
GSP
-
SFO
1 stop9h 42m
American Airlines
Deal found 2/13$380
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:25 am
SFO
-
GSP
2 stops9h 25m
Southwest
Wed 4/221:55 pm
GSP
-
SFO
1 stop10h 30m
Southwest
Deal found 2/10$385
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:55 pm
SFO
-
GSP
1 stop10h 05m
Southwest
Sat 4/256:25 am
GSP
-
SFO
2 stops12h 00m
Southwest
Deal found 2/10$396
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:55 pm
SFO
-
GSP
1 stop10h 05m
Southwest
Mon 4/271:50 pm
GSP
-
SFO
1 stop12h 30m
Southwest
Deal found 2/10$404
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2011:25 pm
SFO
-
GSP
2 stops9h 35m
Southwest
Wed 3/251:50 pm
GSP
-
SFO
1 stop11h 15m
Southwest
Deal found 2/9$412
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:55 pm
SFO
-
GSP
1 stop10h 05m
Southwest
Sun 3/226:30 am
GSP
-
SFO
1 stop12h 40m
Southwest
Deal found 2/9$418
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:59 am
SFO
-
GSP
1 stop7h 45m
American Airlines
Sun 4/195:20 am
GSP
-
SFO
1 stop9h 56m
American Airlines
Deal found 2/13$419
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:06 pm
SFO
-
GSP
1 stop8h 48m
Delta
Fri 3/137:59 pm
GSP
-
SFO
1 stop7h 36m
Delta
Deal found 2/11$425
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:20 pm
SFO
-
GSP
1 stop13h 00m
Southwest
Sun 4/56:30 am
GSP
-
SFO
1 stop12h 40m
Southwest
Deal found 2/12$428

Find flight deals from San Francisco to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$380
(American Airlines)

One-way from

$146
(Kiwi.com)

Popular in

February

Cheapest in

January

Average price

$583
Provider with most accurate pricing for San Francisco-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Greenville flights.
Search Deals
From San Francisco to Greenville
Search Deals
One-way flight from San Francisco to Greenville
Search Deals
High demand for flights, 4% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

San Francisco

Fly to

Greenville

Route

Depart

Return

Price

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 4/20

11:05 pm-11:14 am

1 stop9h 09m

Greenville

Wed 4/22

7:00 am-12:18 pm

1 stop8h 18m

$380

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 4/20

5:25 am-5:50 pm

2 stops9h 25m

Greenville

Wed 4/22

1:55 pm-9:25 pm

1 stop10h 30m

$385

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 4/23

10:55 pm-12:00 pm

1 stop10h 05m

Greenville

Sat 4/25

10:45 am-4:20 pm

1 stop8h 35m

$390

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 4/23

10:55 pm-12:00 pm

1 stop10h 05m

Greenville

Mon 4/27

1:50 pm-11:20 pm

1 stop12h 30m

$404

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 3/12

9:20 pm-1:20 pm

1 stop13h 00m

Greenville

Sat 3/14

12:35 pm-8:15 pm

1 stop10h 40m

$404

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Fri 3/20

11:25 pm-12:00 pm

2 stops9h 35m

Greenville

Wed 3/25

1:50 pm-10:05 pm

1 stop11h 15m

$412

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 4/1

5:55 am-5:45 pm

2 stops8h 50m

Greenville

Sun 4/5

6:30 am-1:50 pm

2 stops10h 20m

$417

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 3/17

10:55 pm-12:00 pm

1 stop10h 05m

Greenville

Sun 3/22

6:30 am-4:10 pm

1 stop12h 40m

$418

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 3/11

6:00 am-3:56 pm

3 stops30h 56m

$146

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 3/24

7:32 pm-8:56 pm

3 stops46h 24m

$160

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Showing 1-10 of 18 results
1
2

Compare providers for flights from San Francisco to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Greenville

How far ahead should I book a flight from San Francisco to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Greenville. Price data was last updated on February 6, 2026.

To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Greenville?

Currently, April is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $174). Flying from San Francisco to Greenville in February is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated February 13, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,284 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,284 reviews
Southwest
8.0
Very good
4,284 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,203 reviews
Southwest
8.0
Very good
4,284 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,289 reviews
Southwest
8.0
Very good
4,284 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,288 reviews
Southwest
8.0
Very good
4,284 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Greenville?

    United Airlines and Southwest can get you from San Francisco to Greenville in just under 9h 09m. Your travel time can differ by up to 16m. San Francisco and Greenville are separated by a distance of 2227 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Francisco to Greenville round-trip?

    Cheapflights users have booked flights from San Francisco to Greenville round-trip from $236. Other airlines that can offer you cheap pricing are Delta, from $278, and Southwest, from $313. American Airlines is currently priced 49% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from San Francisco to Greenville one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $102. Delta flights start at $147 while deals on American Airlines start at $166 one-way.

  • Can I find deals for flights from San Francisco to Greenville that include hotel bookings?

    Yes. In addition to deals on San Francisco to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Greenville.

  • Can I find deals for business class flights from San Francisco to Greenville?

    Yes. Cheapflights offers flight deals from San Francisco to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Greenville?

    Currently, April is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $174). Flying from San Francisco to Greenville in February is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 4 airlines flying from San Francisco to Greenville

Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$442FlexibilityNo cancel feeOn-time71%
DeltaCheapest$278Average$457FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$313Average$434FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$424Average$576FlexibilityNo cancel feeOn-time69%

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