$153+ Cheap flights from San Francisco to Greenville (SFO - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Sep 12 — Sep 191
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Greenville
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Cheapest flights from San Francisco to GreenvilleExplore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:30 am -
1 stop8h 05m
Wed 11/45:17 pm -
1 stop10h 22m
Deal found 8/13![American Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:30 pm -
1 stop8h 45m
Tue 9/227:00 am -
2 stops9h 50m
Deal found 8/12![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:40 pm -
2 stops9h 45m
Tue 10/68:30 am -
1 stop9h 05m
Deal found 8/9![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:55 pm -
1 stop9h 15m
Wed 9/3011:04 am -
1 stop10h 05m
Deal found 8/13![Delta logo]()
$348
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:40 pm -
2 stops15h 43m
Tue 11/32:00 pm -
1 stop9h 06m
Deal found 8/12![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:59 pm -
2 stops9h 24m
Tue 11/37:10 am -
1 stop10h 10m
Deal found 8/12![Delta logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:47 pm -
1 stop19h 39m
Mon 8/318:45 pm -
2 stops18h 27m
Deal found 8/10![Multiple Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:03 pm -
1 stop9h 26m
Wed 10/77:46 pm -
1 stop7h 58m
Deal found 8/10![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:30 pm -
1 stop7h 53m
Fri 10/305:40 am -
1 stop7h 55m
Deal found 8/12![Delta logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:47 pm -
1 stop19h 39m
Mon 8/316:19 pm -
1 stop20h 43m
Deal found 8/10![Breeze Airways logo]()
$380
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop8h 59m
Wed 11/185:30 am -
2 stops10h 45m
Deal found 8/12![Delta logo]()
$382
Best flights from San Francisco to GreenvilleDiscover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
Discover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop8h 59m
Wed 11/185:30 am -
2 stops10h 45m
Deal found 8/12![Delta logo]()
$382
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:14 pm -
1 stop7h 34m
Wed 9/307:35 pm -
1 stop8h 24m
Deal found 8/12![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:35 am -
2 stops10h 10m
Mon 10/56:25 am -
2 stops9h 55m
Deal found 8/8![Southwest logo]()
$497
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/95:00 am -
1 stop9h 00m
Sat 2/135:41 pm -
1 stop9h 55m
Deal found 8/10![United Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:55 pm -
1 stop8h 07m
Thu 11/57:43 pm -
1 stop8h 46m
Deal found 8/12![United Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:59 pm -
2 stops10h 11m
Wed 9/3011:04 am -
1 stop10h 05m
Deal found 8/12![Delta logo]()
$464
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:05 pm -
1 stop10h 25m
Sun 9/277:20 am -
2 stops9h 35m
Deal found 8/9![Southwest logo]()
$561
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:59 pm -
2 stops9h 24m
Wed 10/2110:08 am -
1 stop9h 54m
Deal found 8/10![Delta logo]()
$531
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:30 pm -
1 stop7h 53m
Wed 11/46:00 am -
2 stops14h 05m
Deal found 8/9![Delta logo]()
$531
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:24 pm -
1 stop14h 39m
Thu 11/57:43 pm -
1 stop8h 46m
Deal found 8/12![United Airlines logo]()
$550
Last-minute flights from San Francisco to GreenvilleDiscover last-minute flight deals from San Francisco to Greenville. Data last updated August 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Greenville. Data last updated August 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:47 pm -
1 stop19h 39m
Mon 8/318:45 pm -
2 stops18h 27m
Deal found 8/10![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:47 pm -
1 stop19h 39m
Mon 8/316:19 pm -
1 stop20h 43m
Deal found 8/10![Breeze Airways logo]()
$380
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:36 am -
1 stop7h 02m
Sun 9/65:28 pm -
1 stop9h 43m
Deal found 8/9![American Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:30 pm -
1 stop8h 45m
Tue 9/227:00 am -
2 stops9h 50m
Deal found 8/12![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:59 pm -
1 stop8h 25m
Tue 9/227:15 am -
1 stop9h 51m
Deal found 8/12![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:14 pm -
1 stop7h 34m
Wed 9/307:35 pm -
1 stop8h 24m
Deal found 8/12![United Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:55 pm -
1 stop9h 15m
Wed 9/3011:04 am -
1 stop10h 05m
Deal found 8/13![Delta logo]()
$348
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:46 pm -
1 stop9h 17m
Wed 9/308:01 am -
1 stop10h 00m
Deal found 8/11![American Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:40 pm -
2 stops9h 45m
Tue 10/68:30 am -
1 stop9h 05m
Deal found 8/9![Southwest logo]()
$312
One-way flights from San Francisco to GreenvilleSearch for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
Search for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 am -
1 stop7h 21m
Deal found 8/13![American Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:15 am -
2 stops34h 29m
Deal found 8/12![Multiple Airlines logo]()
$156
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:40 pm -
2 stops9h 45m
Deal found 8/13![Southwest logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:24 pm -
3 stops56h 03m
Deal found 8/13![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
2 stops24h 27m
Deal found 8/12![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:48 pm -
3 stops16h 35m
Deal found 8/9![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:14 pm -
2 stops30h 56m
Deal found 8/12![Multiple Airlines logo]()
$174
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:30 am -
1 stop8h 08m
Deal found 8/13![American Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:00 am -
2 stops31h 49m
Deal found 8/8![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:00 pm -
2 stops23h 31m
Deal found 8/12![Multiple Airlines logo]()
$195
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:55 pm -
1 stop9h 15m
Deal found 8/12![Delta logo]()
$196
Find flight deals from San Francisco to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $305 (Delta) |
One-way from | $153 (American Airlines) |
Popular in | May |
Cheapest in | January |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 11/4
6:00 am-5:59 pm
1 stop8h 59m
Greenville
Wed 11/18
5:30 am-1:15 pm
2 stops10h 45m
$382
Quickest round-trip
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Sun 9/20
11:14 pm-9:48 am
1 stop7h 34m
Greenville
Wed 9/30
7:35 pm-12:59 am
1 stop8h 24m
$391
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Tue 2/9
5:00 am-5:00 pm
1 stop9h 00m
Greenville
Sat 2/13
5:41 pm-12:36 am
1 stop9h 55m
$415
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Fri 10/30
10:55 pm-10:02 am
1 stop8h 07m
Greenville
Thu 11/5
7:43 pm-1:29 am
1 stop8h 46m
$418
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Fri 9/25
8:59 pm-10:10 am
2 stops10h 11m
Greenville
Wed 9/30
11:04 am-6:09 pm
1 stop10h 05m
$464
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Fri 10/2
9:35 am-10:45 pm
2 stops10h 10m
Greenville
Mon 10/5
6:25 am-1:20 pm
2 stops9h 55m
$497
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 10/7
8:59 pm-9:23 am
2 stops9h 24m
Greenville
Wed 10/21
10:08 am-5:02 pm
1 stop9h 54m
$531
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 10/21
10:30 pm-9:23 am
1 stop7h 53m
Greenville
Wed 11/4
6:00 am-5:05 pm
2 stops14h 05m
$531
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Thu 10/29
9:24 pm-3:03 pm
1 stop14h 39m
Greenville
Thu 11/5
7:43 pm-1:29 am
1 stop8h 46m
$550
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Thu 9/24
11:05 pm-12:30 pm
1 stop10h 25m
Greenville
Sun 9/27
7:20 am-1:55 pm
2 stops9h 35m
$561
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
SFO-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Greenville
What is the cheapest month to book a flight from San Francisco to Greenville?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $346). Flying from San Francisco to Greenville in May is currently the most expensive (average of $692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Greenville?
Airfare is below average for this route at the moment.
San Francisco to Greenville flights typically cost between $406 and $571 in October.The cheapest round-trip price found within the last 5 days was $305 on American Airlines (Oct 21-Nov 4).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated August 13, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Alternative routes for San Francisco to Greenville
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
San Francisco and Greenville flights
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Francisco to Greenville
Discover the top 3 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$489 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$353 | Average$566 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$424 | Average$544 | FlexibilityNo cancel fee | On-time69% |