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Greenville

$89+ Cheap flights from O'Hare Intl (ORD) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GSP
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Greenville are usually found in July or June, booked 77 days in advance, depart on a Saturday or Tuesday and return on a Thursday

Cheap flight deals from O'Hare Intl to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$218
(Kiwi.com)

One-way from

$89
(American Airlines)

Popular in

November

Cheapest in

July

Average price

$326

Good round-trip deal

$229 or less

Good one-way deal

$168 or less
Provider with most accurate pricing for Chicago O'Hare Intl-Greenville flight deals.
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Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Greenville flights.
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From Chicago O'Hare Intl to Greenville
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One-way flight from Chicago O'Hare Intl to Greenville
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Highest demand for flights based on searches. 13% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to Greenville.
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Price to beat on a one-way flight from Chicago O'Hare Intl to Greenville.
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Find flight deals from O'Hare Intl to Greenville

Cheapest flights from O'Hare Intl to Greenville
Explore the most affordable flight options available from O'Hare Intl to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:32 pmORD - GSP
2 stops24h 33mMultiple Airlines
Mon 12/293:30 pmGSP - ORD
1 stop17h 51mMultiple Airlines
Deal found 10/16$218
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:56 pmORD - GSP
Nonstop1h 53mAmerican Airlines
Mon 11/108:14 pmGSP - ORD
Nonstop2h 16mAmerican Airlines
Deal found 10/14$219
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:40 amORD - GSP
1 stop5h 37mAmerican Airlines
Wed 11/196:00 amGSP - ORD
Nonstop2h 17mAmerican Airlines
Deal found 10/15$220
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1712:09 pmORD - GSP
1 stop26h 06mMultiple Airlines
Tue 12/303:26 pmGSP - ORD
1 stop19h 52mMultiple Airlines
Deal found 10/16$221
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:35 pmORD - GSP
1 stop6h 31mDelta
Mon 11/177:59 pmGSP - ORD
1 stop5h 03mDelta
Deal found 10/16$222
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1712:09 pmORD - GSP
1 stop26h 06mMultiple Airlines
Mon 12/293:30 pmGSP - ORD
1 stop17h 51mMultiple Airlines
Deal found 10/16$223
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:05 amORD - GSP
Nonstop1h 53mAmerican Airlines
Tue 12/28:14 pmGSP - ORD
Nonstop2h 16mAmerican Airlines
Deal found 10/14$226
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:30 pmORD - GSP
1 stop6h 12mDelta
Wed 12/317:30 amGSP - ORD
1 stop6h 24mDelta
Deal found 10/16$228
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:30 pmORD - GSP
1 stop6h 12mDelta
Sun 12/147:25 amGSP - ORD
1 stop7h 25mDelta
Deal found 10/14$229
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:05 amORD - GSP
Nonstop1h 53mAmerican Airlines
Thu 11/208:00 amGSP - ORD
Nonstop2h 18mAmerican Airlines
Deal found 10/15$231
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:14 amORD - GSP
Nonstop1h 58mAmerican Airlines
Sun 12/147:38 amGSP - ORD
1 stop6h 30mAmerican Airlines
Deal found 10/16$232
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:53 pmORD - GSP
Nonstop2h 07mAmerican Airlines
Wed 11/126:01 amGSP - ORD
1 stop5h 35mAmerican Airlines
Deal found 10/15$233

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Greenville that are best for you.

Fly from

O'Hare Intl

Fly to

Greenville

Route

Depart

Return

Price

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 10/29

1:00 pm-7:10 pm

1 stop5h 10m

Greenville

Wed 11/5

9:10 am-10:24 am

Nonstop2h 14m

$222

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 12/12

2:30 pm-9:42 pm

1 stop6h 12m

Greenville

Sun 12/14

7:25 am-1:50 pm

1 stop7h 25m

$229

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Mon 12/22

1:35 pm-9:46 pm

1 stop7h 11m

Greenville

Sat 1/3

6:00 am-9:01 am

1 stop4h 01m

$237

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 11/22

10:46 am-5:52 pm

1 stop6h 06m

Greenville

Wed 11/26

5:35 am-8:41 am

1 stop4h 06m

$237

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 11/27

8:48 am-11:49 am

Nonstop2h 01m

Greenville

Sun 11/30

9:10 am-10:24 am

Nonstop2h 14m

$238

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 10/28

8:50 am-2:20 pm

1 stop4h 30m

Greenville

Mon 11/3

5:28 pm-6:55 pm

Nonstop2h 27m

$239

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 11/8

4:56 pm-7:49 pm

Nonstop1h 53m

Greenville

Mon 11/10

6:19 pm-10:55 pm

1 stop5h 36m

$240

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 11/19

5:06 pm-8:00 pm

Nonstop1h 54m

Greenville

Fri 11/21

5:15 am-10:42 am

1 stop6h 27m

$241

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 12/10

10:35 am-5:33 pm

1 stop5h 58m

Greenville

Sun 12/14

7:25 am-1:50 pm

1 stop7h 25m

$244

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sun 11/23

5:23 am-10:27 am

1 stop4h 04m

Greenville

Tue 12/2

7:25 am-1:50 pm

1 stop7h 25m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 21 results
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Compare providers for flights from O'Hare Intl to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Greenville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Greenville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Greenville. Price data was last updated on October 10, 2025.

The price you pay for your flight from Chicago O'Hare Intl Airport to Greenville may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Greenville?

Currently, February is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Greenville (average of $51). Flying from Chicago O'Hare Intl Airport to Greenville in June is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to GSP?

Find hourly flight availability from O'Hare Intl to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

One of the essential ways to save on airfare from Chicago O'Hare Intl Airport to Greenville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 2% on airfare.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Greenville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Greenville. Price data was last updated on October 12, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Greenville flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 16, 2025.
Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Greenville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,984 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,984 reviews
Delta
8.0
Very good
7,984 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,982 reviews
Delta
8.0
Very good
7,984 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,043 reviews
Delta
8.0
Very good
7,984 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Chicago O'Hare Intl?

    Located just 10.4 mi from the city center, Greenville is the airport most travelers will use when flying to Greenville from Chicago O'Hare Intl. Booking flights from Chicago O'Hare Intl to Greenville (GSP) should be relatively easy as there are 23 daily inbound flights from Chicago O'Hare Intl from 3 different airlines.

  • How long is the flight from Chicago O'Hare Intl Airport to Greenville?

    A quick flight from Chicago O'Hare Intl Airport to Greenville can take about 5h 10m. United Airlines provides one of the quickest options available for as low as $222. There are 577 mi between Chicago O'Hare Intl Airport and Greenville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Greenville round-trip?

    Flying on Delta is currently your cheapest option to Greenville, with prices starting at $148. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $202 and $228, respectively. You may be able to fly from Chicago O'Hare Intl Airport to Greenville for 52% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Greenville one-way?

    $98 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $98 and $99, respectively.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Greenville?

    Before booking your flight to Greenville from Chicago O'Hare Intl Airport, check out the most reliable airlines to get you to your destination on time: GoJet (87%), Republic Airways (87%), United Airlines( 87%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Greenville?

    While on average a flight from Chicago O'Hare Intl Airport to Greenville is generally $246, our data shows the cheapest flight currently is $133. When looking at the most popular route, (Chicago O'Hare Intl - Greenville), you can expect to pay $186 for that flight.

  • Can I find deals for flights from O'Hare Intl to Greenville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Greenville.

  • Can I find deals for business class flights from O'Hare Intl to Greenville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Greenville?

    Currently, February is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Greenville (average of $51). Flying from Chicago O'Hare Intl Airport to Greenville in June is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from O'Hare Intl to Greenville

Discover the top 3 airlines that operate flights from O'Hare Intl to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$148Average$238FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$202Average$288FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$371FlexibilityNo cancel feeOn-time69%

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