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$224+ Cheap flights from South Carolina to Gainesville (GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GNV
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from South Carolina to Gainesville

Keep the following information in mind while searching for South Carolina to Gainesville flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$295
(American Airlines)

One-way from

$224
(American Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Gainesville Regional flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Gainesville Regional flights.
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From South Carolina to Gainesville Regional
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One-way flight from South Carolina to Gainesville Regional
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Find flight deals from South Carolina to Gainesville

Cheapest flights from South Carolina to Gainesville
Explore the most affordable flight options available from South Carolina to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/52:35 pmCLT - GNV
Nonstop1h 42mAmerican Airlines
Tue 9/98:13 pmGNV - CLT
Nonstop1h 37mAmerican Airlines
Deal found 4/29$295
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:40 amCLT - GNV
1 stop3h 47mDelta
Sun 5/2510:12 amGNV - CLT
1 stop3h 24mDelta
Deal found 4/29$315
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/27:35 amGSP - GNV
1 stop4h 52mDelta
Fri 6/67:39 pmGNV - GSP
1 stop4h 13mDelta
Deal found 4/28$367
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/244:16 pmGSP - GNV
2 stops6h 38mAmerican Airlines
Sun 5/255:00 amGNV - GSP
1 stop5h 44mAmerican Airlines
Deal found 4/29$407

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from South Carolina to Gainesville that are best for you.

Fly from

South Carolina

Fly to

Gainesville

Route

Depart

Return

Price

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Tue 6/10

7:15 am-8:51 am

Nonstop1h 36m

Gainesville Regional

Tue 6/17

2:01 pm-3:42 pm

Nonstop1h 41m

$295

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sat 5/24

5:40 am-9:27 am

1 stop3h 47m

Gainesville Regional

Sun 5/25

10:12 am-1:36 pm

1 stop3h 24m

$315

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Mon 6/2

7:35 am-12:27 pm

1 stop4h 52m

Gainesville Regional

Fri 6/6

7:39 pm-11:52 pm

1 stop4h 13m

$367

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Sat 5/24

4:16 pm-10:54 pm

2 stops6h 38m

Gainesville Regional

Sun 5/25

5:00 am-10:44 am

1 stop5h 44m

$407

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Tue 5/13

6:36 pm-12:04 am

1 stop5h 28m

$224

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sat 5/31

7:47 pm-12:27 pm

2 stops16h 40m

$229

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sun 5/25

7:23 am-10:54 pm

2 stops15h 31m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Best time to book a flight from South Carolina to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Gainesville

What is the cheapest month to book a flight from South Carolina to Gainesville?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Gainesville (average of $359). Flying from South Carolina to Gainesville in November is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to GNV?

Find hourly flight availability from South Carolina to Gainesville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Gainesville as you normally would.

Rainfall in Gainesville by month

Plan your trip to Gainesville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Gainesville ranges from 2.1 - 7.1 inches per month. June is typically the wettest month, when rainfall can reach 7.1 in. November is typically the driest time to visit Gainesville when rainfall is around 2.1 in.

Temperature in Gainesville by month

Plan your trip to Gainesville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Gainesville, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated April 30, 2025.
Read reviews from past customers who have flown Delta and American Airlines from South Carolina to Gainesville. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Gainesville from South Carolina?

    Most people fly into Gainesville Regional (GNV) if they book a flight to Gainesville from South Carolina. Gainesville Regional is conveniently located just 4.2 mi from Gainesville’s city center.

  • Can I find deals for flights from South Carolina to Gainesville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Gainesville.

  • Can I find deals for business class flights from South Carolina to Gainesville?

    Yes. Cheapflights offers flight deals from South Carolina to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Gainesville?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Gainesville (average of $359). Flying from South Carolina to Gainesville in November is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Lake City
Alachua

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Top airline flying from South Carolina to Gainesville

Discover the top airline that operate flights from South Carolina to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$280Average$426FlexibilityNo cancel feeOn-time71%

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