HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Fort Myers

$138+ Cheap flights from Knoxville to Fort Myers (TYS - RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — RSW
may. 6 — may. 131
mar. 5/6
mar. 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Fort Myers with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Fort Myers SW Florida Intl are usually found in July or September, booked 34 days in advance, depart on a Wednesday or Saturday and return on a Wednesday

Cheap flight deals from Knoxville to Fort Myers

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mayo 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$138
(Mytrip)

Popular in

March

Cheapest in

July

Average price

$293
Provider with most accurate pricing for Knoxville McGhee Tyson-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Fort Myers SW Florida Intl flights.
Search Deals
From Knoxville McGhee Tyson to Fort Myers SW Florida Intl
Search Deals
One-way flight from Knoxville McGhee Tyson to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from Knoxville to Fort Myers

Cheapest flights from Knoxville to Fort Myers
Explore the most affordable flight options available from Knoxville to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/244:10 pmTYS - RSW
1 stop6h 02mAmerican Airlines
mar. 5/2710:15 amRSW - TYS
1 stop5h 25mAmerican Airlines
Deal found 4/30$249
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/127:44 pmTYS - RSW
1 stop4h 57mDelta
sáb. 6/145:49 pmRSW - TYS
1 stop6h 10mDelta
Deal found 4/29$274
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/39:15 amTYS - RSW
1 stop6h 48mUnited Airlines
lun. 5/57:00 amRSW - TYS
2 stops12h 31mUnited Airlines
Deal found 4/29$344
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/248:10 amTYS - RSW
2 stops32h 03mMultiple Airlines
mar. 5/278:00 amRSW - TYS
3 stops26h 34mMultiple Airlines
Deal found 4/30$494

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 1, 2025.
Use the filters below to find and compare flights from Knoxville to Fort Myers that are best for you.

Fly from

Knoxville

Fly to

Fort Myers

Route

Depart

Return

Price

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

sáb. 5/24

4:10 pm-10:12 pm

1 stop6h 02m

Fort Myers SW Florida Intl

mar. 5/27

10:15 am-3:40 pm

1 stop5h 25m

$249

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

jue. 6/12

7:44 pm-12:41 am

1 stop4h 57m

Fort Myers SW Florida Intl

sáb. 6/14

5:49 pm-11:59 pm

1 stop6h 10m

$274

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

mar. 5/13

7:00 am-2:56 pm

1 stop7h 56m

Fort Myers SW Florida Intl

sáb. 5/17

5:06 pm-11:46 pm

1 stop6h 40m

$354

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

sáb. 5/24

8:10 am-4:13 pm

2 stops32h 03m

Fort Myers SW Florida Intl

mar. 5/27

8:00 am-10:34 am

3 stops26h 34m

$494

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

vie. 5/9

4:55 pm-12:01 pm

1 stop19h 06m

$138

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

jue. 8/7

8:00 am-12:19 pm

2 stops28h 19m

$176

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

jue. 8/7

6:07 pm-11:25 pm

1 stop5h 18m

$195

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

dom. 6/22

5:45 am-9:51 am

1 stop4h 06m

$220

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

mar. 5/27

7:00 am-2:57 pm

1 stop7h 57m

$255

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Compare providers for flights from Knoxville to Fort Myers

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Fort Myers in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Fort Myers flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Fort Myers flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Fort Myers

How far ahead should I book a flight from Knoxville to Fort Myers?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Fort Myers. Price data was last updated on April 25, 2025.

Booking 34 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Fort Myers. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Fort Myers?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Fort Myers (average of $205). Flying from Knoxville to Fort Myers in June is currently the most expensive (average of $297). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to RSW?

Find hourly flight availability from Knoxville to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mayo 1, 2025.

When flying from Knoxville to Fort Myers, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 21% versus a flight in the morning.

Rainfall in Fort Myers by month

Plan your trip to Fort Myers by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Fort Myers ranges from 1.7 - 10.1 inches per month. June is typically the wettest month, when rainfall can reach 10.1 in. December is typically the driest time to visit Fort Myers when rainfall is around 1.7 in.

Temperature in Fort Myers by month

Plan your trip to Fort Myers by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Fort Myers, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 64.4 F).

Reviews of airlines servicing Fort Myers

Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated mayo 1, 2025.
Get a feel of what it's like to fly with Delta, Avelo Airlines and United Airlines from Knoxville to Fort Myers by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Avelo Airlines
7.5
Good
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Fort Myers round-trip?

    Flying on American Airlines is currently your cheapest option to Fort Myers, with prices starting at $249. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $274 and $354, respectively. American Airlines is 22% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Knoxville to Fort Myers one-way?

    The cheapest airlines for a one-way flight from Knoxville to Fort Myers are Avelo Airlines ($138), American Airlines ($195), and Delta ($220).

  • Can I find deals for flights from Knoxville to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Knoxville to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Fort Myers.

  • Can I find deals for business class flights from Knoxville to Fort Myers?

    Yes. Cheapflights offers flight deals from Knoxville to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Fort Myers?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Fort Myers (average of $205). Flying from Knoxville to Fort Myers in June is currently the most expensive (average of $297). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Fort Myers

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Fort Lauderdale flights
Memphis to Miami flights
Nashville to Orlando flights
Memphis to Orlando flights
Nashville to Miami flights
Nashville to Tampa flights
Chattanooga to Orlando flights
Chattanooga to Tampa flights
Nashville to Key West flights
Memphis to Fort Lauderdale flights
Nashville to West Palm Beach flights
Nashville to Pensacola flights
Chattanooga to Miami flights
Knoxville to Orlando flights
Knoxville to Miami flights
Nashville to Panama City flights
Nashville to Jacksonville flights
Chattanooga to Sarasota flights
Memphis to Tampa flights
Chattanooga to Fort Lauderdale flights
Knoxville to Fort Lauderdale flights
Chattanooga to West Palm Beach flights
Knoxville to Orlando Sanford Intl flights
Nashville to Fort Myers flights
Knoxville to Tampa flights
Nashville to St Petersburg flights
Blountville to Miami flights
Nashville to Sarasota flights
Memphis to Fort Myers flights
Chattanooga to Fort Myers flights
Knoxville to Panama City flights
Memphis to Pensacola flights
Knoxville to Key West flights
Chattanooga to Orlando Sanford Intl flights
Memphis to West Palm Beach flights
Memphis to Sarasota flights
Knoxville to St Petersburg flights
Memphis to Orlando Sanford Intl flights
Memphis to Key West flights
Nashville to Daytona Beach flights
Memphis to Panama City flights
Chattanooga to Panama City flights
Memphis to Jacksonville flights
Blountville to Orlando flights
Chattanooga to Jacksonville flights
Knoxville to Pensacola flights
Chattanooga to Daytona Beach flights
Knoxville to West Palm Beach flights
Memphis to St Petersburg flights
Nashville to Melbourne flights

Top 2 airlines flying from Knoxville to Fort Myers

Discover the top 2 airlines that operate flights from Knoxville to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$223Average$293FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$238Average$350FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.