$141+ Cheap flights from Knoxville to Fort Myers (TYS - RSW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — RSW
Jun 27 — Jul 41
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Fort Myers with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Knoxville to Fort MyersExplore the most affordable flight options available from Knoxville to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 28, 2026.
Explore the most affordable flight options available from Knoxville to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 28, 2026.
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:45 pm
TYS
- RSW
1 stop9h 15m
Southwest
Wed 7/16:10 am
RSW
- TYS
1 stop10h 50m
Southwest
Deal found 5/27![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:55 am
TYS
- RSW
1 stop8h 20m
Southwest
Mon 10/197:20 am
RSW
- TYS
1 stop9h 25m
Southwest
Deal found 5/25![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 am
TYS
- RSW
1 stop4h 29m
Delta
Mon 10/195:35 am
RSW
- TYS
1 stop5h 31m
Delta
Deal found 5/27![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 pm
TYS
- RSW
1 stop4h 45m
American Airlines
Sat 9/124:14 pm
RSW
- TYS
1 stop4h 52m
American Airlines
Deal found 5/27![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:00 am
TYS
- RSW
1 stop4h 06m
American Airlines
Mon 6/293:57 pm
RSW
- TYS
1 stop6h 01m
American Airlines
Deal found 5/25![American Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:54 pm
TYS
- RSW
1 stop5h 19m
Delta
Tue 7/216:45 am
RSW
- TYS
1 stop4h 25m
Delta
Deal found 5/26![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
- RSW
2 stops13h 00m
Southwest
Mon 6/296:15 am
RSW
- TYS
1 stop7h 30m
Southwest
Deal found 5/25![Southwest logo]()
$313
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:35 pm
TYS
- RSW
2 stops9h 20m
Southwest
Tue 7/214:40 pm
RSW
- TYS
1 stop3h 45m
Southwest
Deal found 5/26![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:45 am
TYS
- RSW
1 stop4h 09m
Delta
Sun 9/611:00 am
RSW
- TYS
1 stop4h 30m
Delta
Deal found 5/26![Delta logo]()
$329
Best flights from Knoxville to Fort MyersDiscover carefully curated flight deals from Knoxville to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 28, 2026.
Discover carefully curated flight deals from Knoxville to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 28, 2026.
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 am
TYS
- RSW
1 stop4h 29m
Delta
Mon 10/195:35 am
RSW
- TYS
1 stop5h 31m
Delta
Deal found 5/27![Delta logo]()
$298
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:55 am
TYS
- RSW
2 stops12h 55m
Southwest
Mon 10/197:20 am
RSW
- TYS
1 stop9h 25m
Southwest
Deal found 5/25![Southwest logo]()
$298
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:49 pm
TYS
- RSW
1 stop4h 34m
Delta
Fri 7/175:35 am
RSW
- TYS
1 stop4h 01m
Delta
Deal found 5/26![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:50 am
TYS
- RSW
1 stop6h 20m
Southwest
Sun 9/2012:40 pm
RSW
- TYS
2 stops8h 05m
Southwest
Deal found 5/24![Southwest logo]()
$382
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:46 pm
TYS
- RSW
1 stop5h 15m
Delta
Mon 6/296:45 am
RSW
- TYS
1 stop4h 24m
Delta
Deal found 5/23![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:30 pm
TYS
- RSW
1 stop7h 45m
Southwest
Sat 9/127:30 am
RSW
- TYS
2 stops10h 10m
Southwest
Deal found 5/27![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:40 am
TYS
- RSW
1 stop3h 51m
Delta
Sun 6/285:37 am
RSW
- TYS
1 stop4h 01m
Delta
Deal found 5/23![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:50 am
TYS
- RSW
2 stops11h 00m
Southwest
Sat 9/127:30 am
RSW
- TYS
2 stops10h 10m
Southwest
Deal found 5/27![Southwest logo]()
$419
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1812:35 pm
TYS
- RSW
2 stops9h 15m
Southwest
Mon 6/226:15 am
RSW
- TYS
2 stops14h 55m
Southwest
Deal found 5/27![Southwest logo]()
$439
Last-minute flights from Knoxville to Fort MyersDiscover last-minute flight deals from Knoxville to Fort Myers. Data last updated May 28, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Fort Myers. Data last updated May 28, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:35 pm
TYS
- RSW
1 stop9h 20m
Southwest
Tue 6/306:10 am
RSW
- TYS
1 stop10h 50m
Southwest
Deal found 5/26![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 am
TYS
- RSW
1 stop4h 06m
American Airlines
Mon 6/223:57 pm
RSW
- TYS
1 stop6h 01m
American Airlines
Deal found 5/26![American Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:45 pm
TYS
- RSW
1 stop9h 15m
Southwest
Mon 6/226:15 am
RSW
- TYS
2 stops14h 55m
Southwest
Deal found 5/26![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1712:45 pm
TYS
- RSW
1 stop9h 15m
Southwest
Mon 6/226:15 am
RSW
- TYS
2 stops14h 55m
Southwest
Deal found 5/26![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:00 am
TYS
- RSW
1 stop4h 06m
American Airlines
Sat 6/276:01 am
RSW
- TYS
1 stop4h 35m
American Airlines
Deal found 5/23![American Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:46 pm
TYS
- RSW
1 stop5h 15m
Delta
Mon 6/296:45 am
RSW
- TYS
1 stop4h 24m
Delta
Deal found 5/23![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:00 am
TYS
- RSW
1 stop4h 06m
American Airlines
Mon 6/293:57 pm
RSW
- TYS
1 stop6h 01m
American Airlines
Deal found 5/25![American Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
- RSW
2 stops13h 00m
Southwest
Mon 6/296:15 am
RSW
- TYS
1 stop7h 30m
Southwest
Deal found 5/25![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:35 am
TYS
- RSW
1 stop4h 39m
Delta
Mon 6/2910:30 am
RSW
- TYS
1 stop4h 19m
Delta
Deal found 5/25![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:45 pm
TYS
- RSW
1 stop9h 15m
Southwest
Wed 7/16:10 am
RSW
- TYS
1 stop10h 50m
Southwest
Deal found 5/27![Southwest logo]()
$276
One-way flights from Knoxville to Fort MyersSearch for one-way flight options from Knoxville to Fort Myers. Find affordable one-way fares based on user searches. Data last updated May 28, 2026.
Search for one-way flight options from Knoxville to Fort Myers. Find affordable one-way fares based on user searches. Data last updated May 28, 2026.
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:40 am
TYS
- RSW
1 stop4h 03m
Delta
Deal found 5/27![Delta logo]()
$141
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:00 am
TYS
- RSW
1 stop4h 06m
American Airlines
Deal found 5/25![American Airlines logo]()
$160
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:46 pm
TYS
- RSW
1 stop5h 15m
Delta
Deal found 5/25![Delta logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:20 pm
TYS
- RSW
2 stops26h 38m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 am
TYS
- RSW
1 stop3h 47m
Delta
Deal found 5/25![Delta logo]()
$200
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:35 pm
TYS
- RSW
2 stops9h 15m
Southwest
Deal found 5/25![Southwest logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 am
TYS
- RSW
2 stops39h 38m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:15 am
TYS
- RSW
2 stops13h 23m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:00 pm
TYS
- RSW
3 stops44h 03m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:43 pm
TYS
- RSW
2 stops26h 55m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$281
Find flight deals from Knoxville to Fort Myers
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $276 (Southwest) |
One-way from | $141 (Delta) |
Popular in | April |
Cheapest in | February |
Average price | $454 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 28, 2026.
Use the filters below to find and compare flights from Knoxville to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Wed 10/14
5:30 am-9:59 am
1 stop4h 29m
Fort Myers SW Florida Intl
Mon 10/19
5:35 am-11:06 am
1 stop5h 31m
$298
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Wed 10/14
8:55 am-9:50 pm
2 stops12h 55m
Fort Myers SW Florida Intl
Mon 10/19
7:20 am-4:45 pm
1 stop9h 25m
$298
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Mon 7/13
7:49 pm-12:23 am
1 stop4h 34m
Fort Myers SW Florida Intl
Fri 7/17
5:35 am-9:36 am
1 stop4h 01m
$331
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Mon 6/22
7:46 pm-1:01 am
1 stop5h 15m
Fort Myers SW Florida Intl
Mon 6/29
6:45 am-11:09 am
1 stop4h 24m
$365
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Sat 9/12
6:50 am-1:10 pm
1 stop6h 20m
Fort Myers SW Florida Intl
Sun 9/20
12:40 pm-8:45 pm
2 stops8h 05m
$382
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Sun 9/6
1:30 pm-9:15 pm
1 stop7h 45m
Fort Myers SW Florida Intl
Sat 9/12
7:30 am-5:40 pm
2 stops10h 10m
$413
Quickest round-trip
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Sun 6/21
5:40 am-9:31 am
1 stop3h 51m
Fort Myers SW Florida Intl
Sun 6/28
5:37 am-9:38 am
1 stop4h 01m
$415
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Sat 9/5
7:50 am-6:50 pm
2 stops11h 00m
Fort Myers SW Florida Intl
Sat 9/12
7:30 am-5:40 pm
2 stops10h 10m
$419
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Thu 6/18
12:35 pm-9:50 pm
2 stops9h 15m
Fort Myers SW Florida Intl
Mon 6/22
6:15 am-9:10 pm
2 stops14h 55m
$439
Cheapest one-way
Quickest one-way
KnoxvilleFort Myers
TYS - RSW
TYSRSW
Knoxville McGhee Tyson
Tue 7/21
5:40 am-9:43 am
1 stop4h 03m
$141
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Fort Myers
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Fort Myers in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Fort Myers flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Knoxville with our price prediction graph.
TYS-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Fort Myers
What is the cheapest month to book a flight from Knoxville to Fort Myers?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Fort Myers (average of $180). Flying from Knoxville to Fort Myers in April is currently the most expensive (average of $506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Fort Myers?
Reviews of airlines servicing Fort Myers
Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated May 28, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Knoxville to Fort Myers to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.9
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.9
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
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Top 2 airlines flying from Knoxville to Fort Myers
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$253 | Average$437 | FlexibilityNo cancel fee | On-timeN/A |