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Florida Keys

$169+ Cheap flights from South Dakota to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from South Dakota to Florida Keys

Keep the following information in mind while searching for South Dakota to Florida Keys flight deals. Data was last updated September 16, 2025.

Round-trip from

$264
(Kiwi.com)

One-way from

$169
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$343
From South Dakota to Florida Keys
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One-way flight from South Dakota to Florida Keys
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Highest demand for flights based on searches. 11% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from South Dakota to Florida Keys

Cheapest flights from South Dakota to Florida Keys
Explore the most affordable flight options available from South Dakota to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:23 pmFSD - MIA
1 stop14h 56mFrontier
Sun 11/166:00 amMIA - FSD
1 stop8h 38mFrontier
Deal found 9/14$264
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:23 pmFSD - MIA
2 stops18h 48mMultiple Airlines
Mon 11/36:00 amMIA - FSD
1 stop15h 02mMultiple Airlines
Deal found 9/16$283
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:27 pmFSD - MIA
1 stop7h 07mAmerican Airlines
Sat 11/87:09 amMIA - FSD
1 stop6h 12mAmerican Airlines
Deal found 9/14$289
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:59 amFSD - EYW
2 stops9h 50mAmerican Airlines
Wed 11/121:23 pmEYW - FSD
2 stops10h 04mAmerican Airlines
Deal found 9/14$293
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:51 pmRAP - MIA
2 stops7h 55mDelta
Tue 12/97:00 amMIA - RAP
2 stops10h 45mDelta
Deal found 9/15$299
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/192:54 pmFSD - MIA
1 stop8h 50mFrontier
Sun 9/216:00 amMIA - FSD
1 stop9h 09mFrontier
Deal found 9/15$310
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:32 pmFSD - MIA
1 stop7h 03mAmerican Airlines
Sun 11/95:18 amMIA - FSD
1 stop8h 05mAmerican Airlines
Deal found 9/16$344
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:18 amRAP - MIA
2 stops13h 01mAmerican Airlines
Tue 12/96:00 amMIA - RAP
1 stop9h 12mAmerican Airlines
Deal found 9/14$358
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/234:28 pmRAP - MIA
2 stops12h 45mAmerican Airlines
Mon 10/275:15 amMIA - RAP
1 stop8h 33mAmerican Airlines
Deal found 9/16$367
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:00 amFSD - EYW
1 stop6h 19mUnited Airlines
Sat 11/14:00 pmEYW - FSD
1 stop6h 46mUnited Airlines
Deal found 9/15$373
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:30 amFSD - EYW
1 stop4h 57mDelta
Sat 11/17:40 amEYW - FSD
2 stops9h 04mDelta
Deal found 9/15$376
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:37 pmFSD - MIA
1 stop15h 44mMultiple Airlines
Tue 9/307:54 pmMIA - FSD
2 stops39h 57mMultiple Airlines
Deal found 9/14$377

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from South Dakota to Florida Keys that are best for you.

Fly from

South Dakota

Fly to

Florida Keys

Route

Depart

Return

Price

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Thu 10/30

2:23 pm-10:11 am

2 stops18h 48m

Miami

Mon 11/3

6:00 am-8:02 pm

1 stop15h 02m

$283

Rapid CityMiami

RAP - MIA

RAPMIA

Rapid City

Wed 1/14

6:20 am-5:43 pm

1 stop9h 23m

Miami

Wed 1/28

2:30 pm-10:14 pm

1 stop9h 44m

$289

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Sat 11/1

1:27 pm-9:34 pm

1 stop7h 07m

Miami

Sat 11/8

7:09 am-12:21 pm

1 stop6h 12m

$289

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/8

10:59 am-9:49 pm

2 stops9h 50m

Key West

Wed 11/12

1:23 pm-10:27 pm

2 stops10h 04m

$293

Rapid CityMiami

RAP - MIA

RAPMIA

Rapid City

Wed 1/14

10:40 am-12:57 am

2 stops12h 17m

Miami

Tue 1/27

2:30 pm-10:14 pm

1 stop9h 44m

$294

Rapid CityMiami

RAP - MIA

RAPMIA

Rapid City

Tue 1/13

6:20 am-9:07 pm

2 stops12h 47m

Miami

Wed 1/28

2:30 pm-10:14 pm

1 stop9h 44m

$294

Rapid CityMiami

RAP - MIA

RAPMIA

Rapid City

Tue 1/13

6:20 am-5:43 pm

1 stop9h 23m

Miami

Fri 1/23

12:01 pm-10:14 pm

2 stops12h 13m

$294

Rapid CityMiami

RAP - MIA

RAPMIA

Rapid City

Tue 1/13

10:40 am-12:57 am

2 stops12h 17m

Miami

Thu 1/22

2:30 pm-10:14 pm

1 stop9h 44m

$319

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Fri 10/31

1:32 pm-9:35 pm

1 stop7h 03m

Miami

Sun 11/9

5:18 am-12:23 pm

1 stop8h 05m

$344

Rapid CityMiami

RAP - MIA

RAPMIA

Rapid City

Wed 12/3

5:18 am-8:19 pm

2 stops13h 01m

Miami

Tue 12/9

7:04 am-1:12 pm

1 stop8h 08m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 39 results
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Best time to book a flight from South Dakota to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Florida Keys

What is the cheapest month to book a flight from South Dakota to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from South Dakota to Florida Keys (average of $328). Flying from South Dakota to Florida Keys in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Florida Keys?

    A quick flight from South Dakota to Florida Keys can take about 6h 19m. Delta provides one of the quickest options available for as low as $373. South Dakota and Florida Keys are separated by a distance of 1563 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Dakota to Florida Keys one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $169. Users have also found prices from $286 and $291 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from South Dakota to Florida Keys that include hotel bookings?

    Yes. In addition to deals on South Dakota to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Florida Keys.

  • Can I find deals for business class flights from South Dakota to Florida Keys?

    Yes. Cheapflights offers flight deals from South Dakota to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from South Dakota to Florida Keys (average of $328). Flying from South Dakota to Florida Keys in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from South Dakota to Florida Keys

Discover the top 3 airlines that operate flights from South Dakota to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$528FlexibilityNo cancel feeOn-time71%
DeltaCheapest$310Average$593FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$378Average$644FlexibilityNo cancel feeOn-time69%

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