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Florida Keys

$84+ Cheap flights from Missouri to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
may. 6 — may. 131
mar. 5/6
mar. 5/13
1 adult, Economy
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Cheap flight deals from Missouri to Florida Keys

Keep the following information in mind while searching for Missouri to Florida Keys flight deals. Data was last updated mayo 1, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$209
(American Airlines)

One-way from

$84
(Cheapflightsfares)

Popular in

March

Cheapest in

September

Average price

$388
Provider with most accurate pricing for Kansas City-Miami flight deals.
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From Missouri to Florida Keys
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One-way flight from Missouri to Florida Keys
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Highest demand for flights based on searches. 5% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Missouri to Florida Keys

Cheapest flights from Missouri to Florida Keys
Explore the most affordable flight options available from Missouri to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/36:28 pmSGF - MIA
1 stop5h 01mAmerican Airlines
mié. 7/96:40 amMIA - SGF
1 stop7h 58mAmerican Airlines
Deal found 4/30$209
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/288:44 amSTL - MIA
1 stop9h 09mSpirit Airlines
jue. 7/317:58 pmMIA - STL
1 stop12h 51mSpirit Airlines
Deal found 4/30$215
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/126:45 pmSGF - MIA
1 stop5h 07mDelta
sáb. 9/138:05 amMIA - SGF
1 stop7h 45mDelta
Deal found 4/29$217
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/166:53 pmSTL - MIA
1 stop9h 29mFrontier
mar. 5/206:00 amMIA - STL
1 stop28h 59mFrontier
Deal found 4/30$218
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/11:30 pmSTL - EYW
1 stop5h 14mDelta
mar. 10/72:35 pmEYW - STL
1 stop4h 27mDelta
Deal found 4/30$223
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/16:00 amSTL - EYW
2 stops7h 40mAmerican Airlines
mar. 10/75:16 pmEYW - STL
1 stop7h 13mAmerican Airlines
Deal found 4/30$228
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 7/2712:04 pmMCI - MIA
1 stop6h 23mDelta
jue. 8/77:00 amMIA - MCI
1 stop4h 59mDelta
Deal found 4/30$231
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/246:45 pmMCI - MIA
1 stop9h 58mSpirit Airlines
mar. 5/278:55 pmMIA - MCI
1 stop21h 50mSpirit Airlines
Deal found 4/30$232
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/175:31 amSTL - MIA
Nonstop2h 49mAmerican Airlines
mié. 9/249:00 pmMIA - STL
Nonstop3h 01mAmerican Airlines
Deal found 4/30$241
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/253:05 pmSGF - MIA
1 stop6h 37mUnited Airlines
jue. 10/3012:15 pmMIA - SGF
1 stop6h 12mUnited Airlines
Deal found 4/29$243
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/125:07 amMCI - MIA
Nonstop3h 10mAmerican Airlines
sáb. 8/1610:16 pmMIA - MCI
Nonstop3h 13mAmerican Airlines
Deal found 4/30$256
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/167:00 amSGF - EYW
1 stop7h 19mAmerican Airlines
sáb. 8/2312:50 pmEYW - SGF
1 stop5h 55mAmerican Airlines
Deal found 4/29$259

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 1, 2025.
Use the filters below to find and compare flights from Missouri to Florida Keys that are best for you.

Fly from

Missouri

Fly to

Florida Keys

Route

Depart

Return

Price

SpringfieldMiami

SGF - MIA

SGFMIA

Springfield-Branson

jue. 7/3

6:28 pm-12:29 am

1 stop5h 01m

Miami

mié. 7/9

6:40 am-1:38 pm

1 stop7h 58m

$209

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

lun. 7/28

8:44 am-6:53 pm

1 stop9h 09m

Miami

jue. 7/31

7:58 pm-7:49 am

1 stop12h 51m

$215

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

vie. 5/16

6:53 pm-5:22 am

1 stop9h 29m

Miami

mar. 5/20

6:00 am-9:59 am

1 stop28h 59m

$218

SpringfieldMiami

SGF - MIA

SGFMIA

Springfield-Branson

mié. 5/14

6:56 pm-12:37 am

1 stop4h 41m

Miami

mar. 5/20

5:59 pm-10:17 pm

1 stop5h 18m

$219

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

vie. 5/30

5:00 am-2:37 pm

2 stops8h 37m

Key West

mar. 6/3

5:24 pm-9:26 pm

1 stop5h 02m

$228

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

dom. 7/27

12:04 pm-7:27 pm

1 stop6h 23m

Miami

mié. 8/6

8:02 am-12:03 pm

1 stop5h 01m

$231

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

sáb. 5/24

6:45 pm-5:43 am

1 stop9h 58m

Miami

mar. 5/27

8:55 pm-5:45 pm

1 stop21h 50m

$232

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

mié. 5/14

5:13 am-8:59 am

Nonstop2h 46m

Miami

mar. 5/20

8:18 pm-10:19 pm

Nonstop3h 01m

$249

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

mar. 5/20

1:09 pm-8:07 pm

1 stop5h 58m

Key West

jue. 6/5

6:25 pm-11:38 pm

1 stop6h 13m

$259

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

sáb. 8/16

7:00 am-3:19 pm

1 stop7h 19m

Key West

sáb. 8/23

12:50 pm-5:45 pm

1 stop5h 55m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 56 results
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Best time to book a flight from Missouri to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Florida Keys

What is the cheapest month to book a flight from Missouri to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Missouri to Florida Keys (average of $328). Flying from Missouri to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to EOA?

Find hourly flight availability from Missouri to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mayo 1, 2025.

When flying from Missouri to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated mayo 1, 2025.
See what other customers who have flown with Alaska Airlines, Southwest and Delta from Missouri to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,968 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.1

Crew

8.5

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,968 reviews
Alaska Airlines
8.0
Very good
9,968 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.1

Crew

8.5

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,294 reviews
Alaska Airlines
8.0
Very good
9,968 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.1

Crew

8.5

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,934 reviews
Alaska Airlines
8.0
Very good
9,968 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.1

Crew

8.5

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,968 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.1

Crew

8.5

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,968 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.1

Crew

8.5

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Florida Keys one-way?

    One-way options have recently been found by users for as low as $84 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $89 and American Airlines from $100 one-way.

  • Can I find deals for flights from Missouri to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Missouri to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Florida Keys.

  • Can I find deals for business class flights from Missouri to Florida Keys?

    Yes. Cheapflights offers flight deals from Missouri to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Florida Keys (average of $328). Flying from Missouri to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Florida Keys

Discover the top 3 airlines that operate flights from Missouri to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$189Average$403FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$430FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$486FlexibilityNo cancel feeOn-time69%

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