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$575+ Cheap flights from Wilkes-Barre, PA to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — FLO
Mar 1 — Mar 81
Sun 3/1
Sun 3/8
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Florence

Cheapest flights from Wilkes-Barre to Florence
Explore the most affordable flight options available from Wilkes-Barre to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2026.

This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:40 pm
AVP
-
FLO
1 stop6h 17m
American Airlines
Thu 3/56:20 pm
FLO
-
AVP
1 stop5h 32m
American Airlines
Deal found 1/29$575

Find flight deals from Wilkes-Barre to Florence

Keep the following information in mind while searching for Wilkes-Barre to Florence flight deals. Data was last updated January 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$575
(American Airlines)
Provider with most accurate pricing for Wilkes-Barre Scranton-Florence flight deals.
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Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Florence flights.
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From Wilkes-Barre to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to Florence that are best for you.

Fly from

Wilkes-Barre

Fly to

Florence

Route

Depart

Return

Price

ScrantonFlorence

AVP - FLO

AVPFLO

Wilkes-Barre Scranton

Thu 2/26

5:40 pm-11:57 pm

1 stop6h 17m

Florence

Thu 3/5

6:20 pm-11:52 pm

1 stop5h 32m

$575

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Best time to book a flight from Wilkes-Barre to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Florence

What is the cheapest month to book a flight from Wilkes-Barre to Florence, South Carolina?

Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to Florence, South Carolina (average of $83). Flying from Wilkes-Barre to Florence, South Carolina in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Wilkes-Barre?

    Located just 2.3 mi from the city center, Florence is the airport most travelers will use when flying to Florence from Wilkes-Barre. Booking flights from Wilkes-Barre to Florence (FLO) should be relatively easy as there are 0 daily inbound flights from Wilkes-Barre from 0 different airlines.

  • How long is the flight from Wilkes-Barre to Florence, South Carolina?

    American Airlines can get you from Wilkes-Barre to Florence, South Carolina in just under 6h 17m. Your travel time can differ by up to . The distance between Wilkes-Barre and Florence, South Carolina is about 540 mi.

  • Can I find deals for flights from Wilkes-Barre to Florence that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Florence.

  • Can I find deals for business class flights from Wilkes-Barre to Florence?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to Florence, South Carolina?

    Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to Florence, South Carolina (average of $83). Flying from Wilkes-Barre to Florence, South Carolina in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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