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$362+ Cheap flights from Kissimmee, FL to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
MCO — FLO
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Kissimmee to Florence

Cheapest flights from Kissimmee to Florence
Explore the most affordable flight options available from Kissimmee to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 amMCO - FLO
1 stop5h 45mAmerican Airlines
Tue 12/26:15 amFLO - MCO
1 stop3h 52mAmerican Airlines
Deal found 10/28$417
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:53 pmMCO - FLO
1 stop4h 12mAmerican Airlines
Wed 12/106:15 amFLO - MCO
1 stop3h 51mAmerican Airlines
Deal found 10/29$471
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:41 pmMCO - FLO
1 stop4h 00mAmerican Airlines
Sun 11/2311:11 amFLO - MCO
1 stop4h 14mAmerican Airlines
Deal found 10/30$517

Cheap flight deals from Kissimmee to Florence

Keep the following information in mind while searching for Kissimmee to Florence flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$417
(American Airlines)

One-way from

$362
(American Airlines)
Provider with most accurate pricing for Orlando (ORL)-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Orlando (ORL)-Florence flights.
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From Kissimmee to Florence
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One-way flight from Kissimmee to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Kissimmee to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Kissimmee to Florence that are best for you.

Fly from

Kissimmee

Fly to

Florence

Route

Depart

Return

Price

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Tue 11/25

3:01 pm-11:41 pm

2 stops8h 40m

Florence

Tue 12/2

10:29 am-2:01 pm

1 stop3h 32m

$422

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Thu 12/4

1:53 pm-6:05 pm

1 stop4h 12m

Florence

Wed 12/10

6:15 am-10:06 am

1 stop3h 51m

$471

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Thu 11/20

7:41 pm-11:41 pm

1 stop4h 00m

Florence

Sun 11/23

11:11 am-3:25 pm

1 stop4h 14m

$517

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Tue 11/11

6:00 am-10:47 am

1 stop4h 47m

$362

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Wed 11/12

6:00 am-9:54 am

1 stop3h 54m

$362

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Mon 11/10

9:10 am-5:09 pm

2 stops7h 59m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Best time to book a flight from Kissimmee to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Kissimmee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Kissimmee to Florence

What is the cheapest month to book a flight from Kissimmee to Florence, South Carolina?

Currently, December is the cheapest month in which you can book a flight from Kissimmee to Florence, South Carolina (average of $39). Flying from Kissimmee to Florence, South Carolina in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Kissimmee to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Kissimmee?

    Florence (FLO) is the airport you will fly into if you book a flight from Kissimmee to Florence. You should not have trouble finding flights to Florence from Kissimmee; the airport handles an average of 0 inbound flights from Kissimmee per day. You should also have plenty of airline options to choose from since 0 airlines have flights to the Florence airport from Kissimmee. It is only a 2.3 mi journey from Florence (FLO) to Florence’s city center.

  • How long is the flight from Kissimmee to Florence, South Carolina?

    There are many flights that can get you from Kissimmee to Florence, South Carolina in 8h 40m. Fly via American Airlines to get the fastest option. The distance between Kissimmee and Florence, South Carolina is about 408 mi.

  • Can I find deals for flights from Kissimmee to Florence that include hotel bookings?

    Yes. In addition to deals on Kissimmee to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Kissimmee to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Kissimmee to Florence.

  • Can I find deals for business class flights from Kissimmee to Florence?

    Yes. Cheapflights offers flight deals from Kissimmee to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Kissimmee to Florence, South Carolina?

    Currently, December is the cheapest month in which you can book a flight from Kissimmee to Florence, South Carolina (average of $39). Flying from Kissimmee to Florence, South Carolina in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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