HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$450+ Cheap flights from Kansas City to Florence, SC (MCI - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — FLO
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Kansas City to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Kansas City to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Kansas City (MCI) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$450
(American Airlines)
From Kansas City to Florence
Search Deals

Find flight deals from Kansas City to Florence

Cheapest flights from Kansas City to Florence
Explore the most affordable flight options available from Kansas City to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amMCI - FLO
2 stops15h 53mAmerican Airlines
Sat 12/136:31 pmFLO - MCI
2 stops17h 04mAmerican Airlines
Deal found 9/13$450

Cheapflights Fare Finder

 
Customize your flight search to find flights from Kansas City to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Kansas City to Florence that are best for you.

Fly from

Kansas City

Fly to

Florence

Route

Depart

Return

Price

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 12/10

6:00 am-10:53 pm

2 stops15h 53m

Florence

Sat 12/13

6:31 pm-10:35 am

2 stops17h 04m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Kansas City to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Kansas City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Kansas City to Florence

What is the cheapest month to book a flight from Kansas City to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Kansas City to Florence, South Carolina (average of $366). Flying from Kansas City to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with American Airlines from Kansas City to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Kansas City to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Kansas City to Florence, South Carolina?

    A quick flight from Kansas City to Florence, South Carolina can take about 15h 53m. American Airlines provides one of the quickest options available for as low as $450. The distance between Kansas City and Florence, South Carolina is about 900 mi.

  • Can I find deals for flights from Kansas City to Florence that include hotel bookings?

    Yes. In addition to deals on Kansas City to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Kansas City to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Kansas City to Florence.

  • Can I find deals for business class flights from Kansas City to Florence?

    Yes. Cheapflights offers flight deals from Kansas City to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Kansas City to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Kansas City to Florence, South Carolina (average of $366). Flying from Kansas City to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Kansas City to Florence

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Charlotte flights
St. Louis to Charleston flights
Kansas City to Charlotte flights
Kansas City to Columbia flights
St. Louis to Savannah flights
St. Louis to Augusta flights
Kansas City to Savannah flights
St. Louis to Columbia flights
Kansas City to Charleston flights
Springfield to Charlotte flights
St. Louis to Myrtle Beach flights
Kansas City to Myrtle Beach flights
St. Louis to Greenville flights
Kansas City to Hilton Head Island flights
Springfield to Columbia flights
Kansas City to Greenville flights
Springfield to Myrtle Beach flights
Springfield to Charleston flights
Springfield to Savannah flights
St. Louis to Hilton Head Island flights
Joplin to Charlotte flights
Springfield to Greenville flights
Springfield to Hilton Head Island flights
Kansas City to Augusta flights
Joplin to Savannah flights
Joplin to Charleston flights
Springfield to Augusta flights
Columbia to Myrtle Beach flights
Joplin to Augusta flights
Columbia to Hilton Head Island flights
St. Louis to Florence flights
Columbia to Charlotte flights
Columbia to Charleston flights
Cape Girardeau to Charlotte flights
Joplin to Columbia flights
Joplin to Hilton Head Island flights

Top airline flying from Kansas City to Florence

Discover the top airline that operate flights from Kansas City to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$414Average$504FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.