$335+ Cheap flights from Amarillo to Florence, SC (AMA - FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — FLO
Oct 24 — Oct 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Amarillo to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Amarillo to Florence
Cheapest
Best
Last-minute
One-way
Cheapest flights from Amarillo to FlorenceExplore the most affordable flight options available from Amarillo to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Amarillo to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:45 pm -
2 stops10h 12m
Wed 10/282:34 pm -
2 stops9h 10m
Deal found 9/21![American Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Mon 10/262:34 pm -
2 stops10h 25m
Deal found 9/21![American Airlines logo]()
$564
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Sun 10/255:09 am -
2 stops8h 06m
Deal found 9/22![American Airlines logo]()
$871
Best flights from Amarillo to FlorenceDiscover carefully curated flight deals from Amarillo to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Amarillo to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:45 pm -
2 stops10h 12m
Wed 10/282:34 pm -
2 stops9h 10m
Deal found 9/21![American Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Mon 10/262:34 pm -
2 stops9h 10m
Deal found 9/24![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Sun 10/255:09 am -
2 stops8h 06m
Deal found 9/22![American Airlines logo]()
$871
Last-minute flights from Amarillo to FlorenceDiscover last-minute flight deals from Amarillo to Florence. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Amarillo to Florence. Data last updated September 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:45 pm -
2 stops10h 12m
Wed 10/282:34 pm -
2 stops9h 10m
Deal found 9/21![American Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Mon 10/262:34 pm -
2 stops10h 25m
Deal found 9/21![American Airlines logo]()
$564
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Sun 10/255:09 am -
2 stops8h 06m
Deal found 9/22![American Airlines logo]()
$871
One-way flights from Amarillo to FlorenceSearch for one-way flight options from Amarillo to Florence. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Amarillo to Florence. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:45 pm -
2 stops10h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$335
Find flight deals from Amarillo to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Amarillo (AMA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Round-trip from | $506 (American Airlines) |
|---|---|
One-way from | $335 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Amarillo to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Amarillo to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
AmarilloFlorence
AMA Amarillo - FLO Florence
AMAFLO
Amarillo
Fri 10/23
12:45 pm-11:57 pm
2 stops10h 12m
Florence
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$335
AmarilloFlorence
AMA Amarillo - FLO Florence
AMAFLO
Amarillo
Wed 10/21
12:45 pm-11:57 pm
2 stops10h 12m
Florence
Wed 10/28
2:34 pm-10:44 pm
2 stops9h 10m
$506
AmarilloFlorence
AMA Amarillo - FLO Florence
AMAFLO
Amarillo
Fri 10/23
12:45 pm-11:57 pm
2 stops10h 12m
Florence
Mon 10/26
2:34 pm-10:44 pm
2 stops9h 10m
$669
AmarilloFlorence
AMA Amarillo - FLO Florence
AMAFLO
Amarillo
Fri 10/23
12:45 pm-11:57 pm
2 stops10h 12m
Florence
Sun 10/25
5:09 am-12:15 pm
2 stops8h 06m
$871
Sorted by cheapest first
Best time to book a flight from Amarillo to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Amarillo with our price prediction graph.
AMA-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Amarillo to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSumter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Florence flight routes
Other flight options
Other flights from Amarillo
Popular flights