$489+ Cheap flights from Amarillo (AMA) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Nov 30 — Dec 71
Round-trip
1 adult, Economy
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Find cheap flights from Amarillo to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Amarillo to South Carolina
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Best
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Cheapest flights from Amarillo to South CarolinaExplore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:24 pm -
1 stop4h 57m
Wed 12/236:23 pm -
1 stop6h 36m
Deal found 10/31![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:01 pm -
1 stop6h 11m
Wed 1/61:54 pm -
1 stop6h 01m
Deal found 10/27![American Airlines logo]()
$622
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:01 pm -
1 stop6h 11m
Tue 12/297:00 am -
1 stop6h 10m
Deal found 10/28![American Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/287:06 pm -
1 stop21h 44m
Sat 1/97:15 am -
1 stop5h 50m
Deal found 10/27![American Airlines logo]()
$666
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:45 am -
2 stops7h 25m
Sun 11/156:40 am -
2 stops8h 45m
Deal found 10/27![Southwest logo]()
$667
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2510:27 am -
1 stop6h 23m
Fri 1/87:15 am -
1 stop5h 50m
Deal found 10/27![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
2 stops11h 14m
Sun 1/104:57 pm -
1 stop7h 01m
Deal found 10/27![American Airlines logo]()
$674
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:06 pm -
2 stops16h 19m
Wed 1/66:15 am -
2 stops11h 46m
Deal found 10/27![American Airlines logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:26 am -
1 stop5h 01m
Sun 11/157:51 am -
1 stop7h 37m
Deal found 10/27![American Airlines logo]()
$683
Best flights from Amarillo to South CarolinaDiscover carefully curated flight deals from Amarillo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
Discover carefully curated flight deals from Amarillo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/612:08 pm -
2 stops11h 37m
Sat 1/910:05 am -
2 stops13h 25m
Deal found 10/30![United Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:01 pm -
1 stop6h 11m
Tue 12/297:00 am -
1 stop6h 10m
Deal found 10/29![American Airlines logo]()
$649
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:45 am -
2 stops7h 25m
Sun 11/156:40 am -
2 stops8h 45m
Deal found 10/27![Southwest logo]()
$667
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:26 am -
1 stop5h 01m
Sun 11/157:51 am -
1 stop7h 37m
Deal found 10/27![American Airlines logo]()
$683
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:27 pm -
2 stops15h 34m
Fri 1/89:45 am -
2 stops13h 45m
Deal found 10/27![United Airlines logo]()
$719
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1112:51 pm -
2 stops9h 51m
Wed 12/236:23 pm -
1 stop6h 36m
Deal found 10/31![American Airlines logo]()
$693
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:27 pm -
2 stops15h 34m
Sat 1/96:15 am -
2 stops11h 31m
Deal found 10/27![United Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:27 pm -
2 stops15h 34m
Thu 1/712:25 pm -
2 stops11h 05m
Deal found 10/27![United Airlines logo]()
$719
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:06 pm -
2 stops16h 19m
Sun 1/101:43 pm -
2 stops10h 15m
Deal found 10/27![American Airlines logo]()
$723
Last-minute flights from Amarillo to South CarolinaDiscover last-minute flight deals from Amarillo to South Carolina. Data last updated October 31, 2026 and is based on user searches.
Discover last-minute flight deals from Amarillo to South Carolina. Data last updated October 31, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:45 am -
2 stops7h 25m
Sun 11/156:40 am -
2 stops8h 45m
Deal found 10/27![Southwest logo]()
$667
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:26 am -
1 stop5h 01m
Sun 11/157:51 am -
1 stop7h 37m
Deal found 10/27![American Airlines logo]()
$683
Find flight deals from Amarillo to South Carolina
Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated October 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $489 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Wed 1/6
12:08 pm-12:45 am
2 stops11h 37m
Columbia Metropolitan
Sat 1/9
10:05 am-10:30 pm
2 stops13h 25m
$489
Quickest round-trip
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Tue 12/22
3:01 pm-10:12 pm
1 stop6h 11m
Columbia Metropolitan
Tue 12/29
7:00 am-12:10 pm
1 stop6h 10m
$649
AmarilloGreenville
AMA Amarillo - GSP Greenville
AMAGSP
Amarillo
Wed 11/11
9:45 am-6:10 pm
2 stops7h 25m
Greenville
Sun 11/15
6:40 am-2:25 pm
2 stops8h 45m
$667
AmarilloGreenville
AMA Amarillo - GSP Greenville
AMAGSP
Amarillo
Wed 11/11
10:26 am-4:27 pm
1 stop5h 01m
Greenville
Sun 11/15
7:51 am-2:28 pm
1 stop7h 37m
$683
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Fri 12/11
12:51 pm-11:42 pm
2 stops9h 51m
Columbia Metropolitan
Wed 12/23
6:23 pm-11:59 pm
1 stop6h 36m
$693
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Mon 12/28
5:27 pm-10:01 am
2 stops15h 34m
Columbia Metropolitan
Fri 1/8
9:45 am-10:30 pm
2 stops13h 45m
$719
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Mon 12/28
5:27 pm-10:01 am
2 stops15h 34m
Columbia Metropolitan
Sat 1/9
6:15 am-4:46 pm
2 stops11h 31m
$719
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Mon 12/28
5:27 pm-10:01 am
2 stops15h 34m
Columbia Metropolitan
Thu 1/7
12:25 pm-10:30 pm
2 stops11h 05m
$719
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Tue 12/29
7:06 pm-12:25 pm
2 stops16h 19m
Columbia Metropolitan
Sun 1/10
1:43 pm-10:58 pm
2 stops10h 15m
$723
Sorted by cheapest first
Best time to book a flight from Amarillo to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
AMA-CAE
AMA-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Amarillo to South Carolina
AMA-USSC
AMA-CAE
AMA-GSP
No data available for this route at this time. Please check back soon.
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