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$447+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Jun 1 — Jun 81
Mon 6/1
Mon 6/8
1 adult, Economy
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Cheap flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 2, 2026.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 am
AMA
-
CHS
1 stop7h 51m
American Airlines
Fri 7/173:41 pm
CHS
-
AMA
1 stop8h 18m
American Airlines
Deal found 4/28$447
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:25 pm
AMA
-
CHS
1 stop5h 25m
Southwest
Fri 7/176:25 am
CHS
-
AMA
2 stops8h 25m
Southwest
Deal found 4/28$452
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:00 pm
AMA
-
CHS
1 stop6h 13m
United Airlines
Wed 8/194:26 pm
CHS
-
AMA
1 stop6h 15m
United Airlines
Deal found 4/27$457
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
AMA
-
CAE
1 stop6h 31m
American Airlines
Mon 9/217:48 pm
CAE
-
AMA
1 stop5h 25m
American Airlines
Deal found 4/28$520
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:00 am
AMA
-
CAE
3 stops11h 16m
United Airlines
Mon 9/212:29 pm
CAE
-
AMA
2 stops8h 12m
United Airlines
Deal found 4/28$1,453

Find flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated May 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$447
(American Airlines)
Provider with most accurate pricing for Amarillo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Amarillo-Myrtle Beach Intl flights.
Search Deals
From Amarillo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 2, 2026.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Sat 7/11

12:25 pm-6:50 pm

1 stop5h 25m

Charleston

Fri 7/17

6:25 am-1:50 pm

2 stops8h 25m

$452
Quickest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 8/18

3:00 pm-10:13 pm

1 stop6h 13m

Charleston

Wed 8/19

7:00 am-11:20 am

1 stop5h 20m

$457

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 9/16

6:00 am-1:31 pm

1 stop6h 31m

Columbia Metropolitan

Mon 9/21

7:48 pm-12:13 am

1 stop5h 25m

$520

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 9/16

9:00 am-9:16 pm

3 stops11h 16m

Columbia Metropolitan

Mon 9/21

2:29 pm-9:41 pm

2 stops8h 12m

$1,453

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Sorted by cheapest first

Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina

How much does it cost to fly round-trip from Amarillo to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 2, 2026.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,673 reviews

Food

6.4

Boarding

7.5

Entertainment

6.9

Crew

7.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,673 reviews
American Airlines
7.1
Good
11,673 reviews

Food

6.4

Boarding

7.5

Entertainment

6.9

Crew

7.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 5h 25m. Southwest provides one of the quickest options available for as low as $452. The distance between Amarillo and South Carolina is about 1247 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Amarillo to South Carolina

Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$370Average$498FlexibilityNo cancel feeOn-time71%

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