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$375+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Jul 17 — Jul 241
Fri 7/17
Fri 7/24
1 adult, Economy
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Cheap flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.

This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am
AMA
-
CHS
1 stop7h 26m
American Airlines
Sat 11/147:00 am
CHS
-
AMA
1 stop5h 50m
American Airlines
Deal found 6/13$375
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:51 pm
AMA
-
CHS
1 stop6h 20m
United Airlines
Wed 8/197:00 am
CHS
-
AMA
1 stop6h 11m
United Airlines
Deal found 6/11$379
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:16 pm
AMA
-
CHS
1 stop5h 34m
American Airlines
Sun 8/167:00 am
CHS
-
AMA
1 stop6h 20m
American Airlines
Deal found 6/15$441
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:17 pm
AMA
-
CAE
1 stop6h 22m
American Airlines
Sun 7/57:23 pm
CAE
-
AMA
1 stop5h 36m
American Airlines
Deal found 6/16$608
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:51 pm
AMA
-
CAE
2 stops17h 52m
United Airlines
Tue 9/110:23 am
CAE
-
AMA
2 stops13h 07m
United Airlines
Deal found 6/11$624
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
AMA
-
CAE
1 stop6h 23m
American Airlines
Sun 7/57:23 pm
CAE
-
AMA
1 stop5h 36m
American Airlines
Deal found 6/16$628
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2212:27 pm
AMA
-
CAE
2 stops10h 40m
American Airlines
Tue 12/292:48 pm
CAE
-
AMA
2 stops10h 06m
American Airlines
Deal found 6/14$663
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
AMA
-
CAE
2 stops24h 47m
United Airlines
Sat 8/296:25 am
CAE
-
AMA
2 stops11h 30m
United Airlines
Deal found 6/15$689
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
AMA
-
CAE
1 stop6h 23m
American Airlines
Sun 7/57:23 pm
CAE
-
AMA
1 stop5h 36m
American Airlines
Deal found 6/16$701

Find flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated June 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$375
(American Airlines)
Provider with most accurate pricing for Amarillo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Amarillo-Myrtle Beach Intl flights.
Search Deals
From Amarillo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Mon 11/9

6:00 am-3:35 pm

2 stops8h 35m

Charleston

Sat 11/14

4:15 pm-11:55 pm

2 stops8h 40m

$386

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 8/18

9:00 am-4:32 pm

1 stop6h 32m

Charleston

Wed 8/19

7:00 am-12:11 pm

1 stop6h 11m

$437

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 10/16

5:30 am-2:35 pm

2 stops8h 05m

Charleston

Sat 10/24

3:30 pm-9:00 pm

1 stop6h 30m

$461
Quickest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 10/16

4:18 pm-10:39 pm

1 stop5h 21m

Charleston

Sat 10/24

7:30 pm-12:13 am

1 stop5h 43m

$466

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Sat 8/29

2:51 pm-9:43 am

2 stops17h 52m

Columbia Metropolitan

Tue 9/1

10:23 am-10:30 pm

2 stops13h 07m

$624

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Tue 8/25

8:00 am-9:47 am

2 stops24h 47m

Columbia Metropolitan

Sat 8/29

6:25 am-4:55 pm

2 stops11h 30m

$689

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 7/1

2:48 pm-7:09 pm

2 stops27h 21m

Columbia Metropolitan

Sun 7/5

7:45 pm-9:50 pm

2 stops27h 05m

$1,176

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Fri 6/26

9:00 am-9:16 pm

3 stops11h 16m

Columbia Metropolitan

Sun 7/5

6:25 am-4:41 pm

2 stops11h 16m

$1,592

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Sat 6/27

9:00 am-9:16 pm

2 stops11h 16m

Columbia Metropolitan

Sun 7/5

6:25 am-4:41 pm

3 stops11h 16m

$1,595

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Sorted by cheapest first

Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 17, 2026.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,666 reviews

Boarding

7.5

Entertainment

6.8

Comfort

7.2

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,666 reviews
American Airlines
7.1
Good
11,666 reviews

Boarding

7.5

Entertainment

6.8

Comfort

7.2

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 6h 32m. American Airlines provides one of the quickest options available for as low as $437. The distance between Amarillo and South Carolina is about 1247 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Amarillo to South Carolina

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Top airline flying from Amarillo to South Carolina

Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$401Average$551FlexibilityNo cancel feeOn-time71%

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