$383+ Cheap flights from Amarillo (AMA) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Amarillo to South CarolinaExplore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:11 am -
1 stop6h 08m
Wed 11/186:30 am -
1 stop5h 52m
Deal found 9/14![United Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:01 pm -
1 stop6h 17m
Tue 12/297:52 am -
1 stop7h 39m
Deal found 9/14![American Airlines logo]()
$585
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:00 am -
2 stops25h 01m
Tue 12/297:42 pm -
2 stops26h 53m
Deal found 9/13![United Airlines logo]()
$835
Best flights from Amarillo to South CarolinaDiscover carefully curated flight deals from Amarillo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Amarillo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:11 am -
1 stop6h 08m
Wed 11/186:30 am -
1 stop5h 52m
Deal found 9/14![United Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2212:45 pm -
2 stops9h 13m
Tue 12/292:35 pm -
2 stops10h 24m
Deal found 9/14![American Airlines logo]()
$866
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/912:07 pm -
2 stops11h 34m
Tue 1/1210:17 am -
2 stops12h 19m
Deal found 9/10![United Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:00 am -
2 stops25h 01m
Tue 12/297:42 pm -
2 stops26h 53m
Deal found 9/13![United Airlines logo]()
$835
Last-minute flights from Amarillo to South CarolinaDiscover last-minute flight deals from Amarillo to South Carolina. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Amarillo to South Carolina. Data last updated September 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:57 pm -
1 stop6h 51m
Thu 9/243:41 pm -
1 stop7h 51m
Deal found 9/13![American Airlines logo]()
$947
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
2 stops10h 40m
Thu 9/2411:05 am -
2 stops12h 25m
Deal found 9/13![United Airlines logo]()
$957
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop7h 51m
Mon 9/284:46 pm -
1 stop5h 32m
Deal found 9/10![American Airlines logo]()
$577
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:50 am -
2 stops10h 40m
Mon 9/2811:35 am -
1 stop6h 35m
Deal found 9/10![Southwest logo]()
$645
Find flight deals from Amarillo to South Carolina
Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $383 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
AmarilloCharleston
AMA Amarillo - CHS Charleston
AMACHS
Amarillo
Tue 11/17
9:11 am-4:19 pm
1 stop6h 08m
Charleston
Wed 11/18
6:30 am-11:22 am
1 stop5h 52m
$383
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Sat 1/9
12:07 pm-12:41 am
2 stops11h 34m
Columbia Metropolitan
Tue 1/12
10:17 am-9:36 pm
2 stops12h 19m
$656
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Tue 12/22
8:00 am-10:01 am
2 stops25h 01m
Columbia Metropolitan
Tue 12/29
7:42 pm-9:35 pm
2 stops26h 53m
$835
AmarilloColumbia
AMA Amarillo - CAE Columbia Metropolitan
AMACAE
Amarillo
Tue 12/22
12:45 pm-10:58 pm
2 stops9h 13m
Columbia Metropolitan
Tue 12/29
2:35 pm-11:59 pm
2 stops10h 24m
$866
Sorted by cheapest first
Best time to book a flight from Amarillo to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
AMA-CHS
AMA-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Amarillo to South Carolina
AMA-USSC
AMA-CHS
AMA-CAE
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 15, 2026.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Crew
7.9
Overall
7.1
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Crew
7.9
Overall
7.1
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Amarillo to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Amarillo and South Carolina flights
Browse other Amarillo and South Carolina flight options. Last updated on September 15, 2026.
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Amarillo to South Carolina flights
Consider these flights traveling from Amarillo to South Carolina.
Top airline flying from Amarillo to South Carolina
Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$443 | Average$551 | FlexibilityNo cancel fee | On-time71% |