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$388+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Aug 31 — Sep 71
Mon 8/31
Mon 9/7
1 adult, Economy
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Cheap flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:58 pm
AMA
-
CHS
1 stop6h 28m
American Airlines
Fri 11/67:00 am
CHS
-
AMA
1 stop8h 28m
American Airlines
Deal found 7/30$388
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:19 pm
AMA
-
CHS
1 stop5h 40m
United Airlines
Fri 11/69:55 am
CHS
-
AMA
2 stops12h 46m
United Airlines
Deal found 7/30$393
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am
AMA
-
CHS
2 stops9h 35m
Southwest
Fri 11/64:00 pm
CHS
-
AMA
2 stops8h 35m
Southwest
Deal found 7/30$399
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:30 pm
AMA
-
CHS
2 stops8h 45m
Southwest
Tue 10/136:40 am
CHS
-
AMA
2 stops7h 30m
Southwest
Deal found 7/31$477
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:58 pm
AMA
-
CAE
1 stop7h 26m
American Airlines
Mon 11/165:10 pm
CAE
-
AMA
1 stop7h 38m
American Airlines
Deal found 7/28$519
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:35 pm
AMA
-
CAE
1 stop4h 31m
American Airlines
Sun 12/207:46 pm
CAE
-
AMA
1 stop5h 08m
American Airlines
Deal found 7/28$520
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:16 pm
AMA
-
CAE
1 stop5h 11m
American Airlines
Tue 8/187:00 am
CAE
-
AMA
1 stop6h 20m
American Airlines
Deal found 7/29$528
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/64:16 pm
AMA
-
CAE
1 stop5h 11m
American Airlines
Sun 8/97:51 pm
CAE
-
AMA
1 stop5h 16m
American Airlines
Deal found 7/27$575
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:00 am
AMA
-
CHS
1 stop6h 42m
American Airlines
Tue 8/187:05 am
CHS
-
AMA
1 stop6h 15m
American Airlines
Deal found 7/30$577
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
AMA
-
CHS
2 stops8h 25m
Southwest
Tue 8/1810:45 am
CHS
-
AMA
1 stop6h 55m
Southwest
Deal found 7/30$582
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am
AMA
-
CHS
1 stop15h 33m
American Airlines
Tue 10/137:08 pm
CHS
-
AMA
1 stop5h 51m
American Airlines
Deal found 7/31$597
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/143:00 pm
AMA
-
CHS
1 stop5h 54m
United Airlines
Tue 12/1510:23 am
CHS
-
AMA
2 stops10h 50m
United Airlines
Deal found 7/27$663

Find flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated August 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$388
(American Airlines)
Provider with most accurate pricing for Amarillo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Amarillo-Myrtle Beach Intl flights.
Search Deals
From Amarillo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 11/3

3:19 pm-9:59 pm

1 stop5h 40m

Charleston

Fri 11/6

9:55 am-9:41 pm

2 stops12h 46m

$393

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Thu 10/8

2:30 pm-12:15 am

2 stops8h 45m

Charleston

Tue 10/13

6:40 am-1:10 pm

2 stops7h 30m

$477

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Fri 8/14

4:16 pm-10:27 pm

1 stop5h 11m

Columbia Metropolitan

Tue 8/18

7:00 am-12:20 pm

1 stop6h 20m

$528

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Sat 8/15

9:00 am-9:28 pm

2 stops11h 28m

Columbia Metropolitan

Wed 8/19

10:22 am-9:54 pm

2 stops12h 32m

$575
Quickest round-trip

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Thu 8/6

4:16 pm-10:27 pm

1 stop5h 11m

Columbia Metropolitan

Sun 8/9

7:51 pm-12:07 am

1 stop5h 16m

$575

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 8/14

6:00 am-3:25 pm

2 stops8h 25m

Charleston

Tue 8/18

10:45 am-4:40 pm

1 stop6h 55m

$582

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Mon 12/14

3:00 pm-9:54 pm

1 stop5h 54m

Charleston

Tue 12/15

10:23 am-8:13 pm

2 stops10h 50m

$663

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Tue 9/1

9:00 am-9:28 pm

2 stops11h 28m

Columbia Metropolitan

Sat 9/5

5:38 pm-11:24 am

3 stops18h 46m

$670

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Sorted by cheapest first

Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 1, 2026.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,846 reviews

Entertainment

6.8

Crew

7.9

Food

6.4

Comfort

7.2

Boarding

7.5

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,846 reviews
American Airlines
7.1
Good
11,846 reviews

Entertainment

6.8

Crew

7.9

Food

6.4

Comfort

7.2

Boarding

7.5

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 5h 11m. United Airlines provides one of the quickest options available for as low as $528. The distance between Amarillo and South Carolina is about 1171 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Amarillo to South Carolina

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Top airline flying from Amarillo to South Carolina

Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$443Average$557FlexibilityNo cancel feeOn-time71%

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