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Ecuador

$171+ Cheap flights from Panama City (PTY) to Ecuador

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — UIO
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Panama City to Ecuador

Keep the following information in mind while searching for Panama City to Ecuador flight deals. Data was last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$324
(Avianca)

One-way from

$171
(Priceline)

Popular in

March

Cheapest in

February

Average price

$330

Good round-trip deal

$347 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Guayaquil Jose Joaquin de Olmedo flights.
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From Panama City Tocumen Intl to Ecuador
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One-way flight from Panama City Tocumen Intl to Ecuador
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Ecuador.
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Find flight deals from Panama City to Ecuador

Cheapest flights from Panama City to Ecuador
Explore the most affordable flight options available from Panama City to Ecuador. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/192:55 amPTY - GYE
1 stop11h 35mAvianca
Tue 12/29:05 amGYE - PTY
1 stop4h 55mAvianca
Deal found 10/21$324
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:55 amPTY - GYE
1 stop6h 20mAvianca
Sun 11/94:40 amGYE - PTY
1 stop9h 20mAvianca
Deal found 10/21$331
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:25 pmPTY - UIO
2 stops13h 25mAvianca
Mon 10/276:30 amUIO - PTY
2 stops10h 25mAvianca
Deal found 10/23$334
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:55 amPTY - GYE
1 stop6h 20mAvianca
Tue 1/66:55 pmGYE - PTY
1 stop6h 05mAvianca
Deal found 10/23$341
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:02 amPTY - GYE
Nonstop2h 16mCopa Airlines
Sat 2/76:33 pmGYE - PTY
Nonstop2h 08mCopa Airlines
Deal found 10/21$348
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:55 pmPTY - UIO
1 stop7h 25mAvianca
Thu 11/66:30 amUIO - PTY
2 stops7h 30mAvianca
Deal found 10/21$350
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/232:55 amPTY - GYE
2 stops9h 25mAvianca
Wed 12/310:25 amGYE - PTY
1 stop6h 30mAvianca
Deal found 10/23$350
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:55 amPTY - GYE
2 stops9h 35mAvianca
Tue 1/63:30 amGYE - PTY
1 stop10h 30mAvianca
Deal found 10/21$351
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:17 amPTY - GYE
Nonstop2h 17mCopa Airlines
Sun 12/712:20 pmGYE - PTY
Nonstop2h 12mCopa Airlines
Deal found 10/21$355
This Priceline deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/272:55 amPTY - UIO
1 stop6h 00mAvianca
Tue 11/116:30 amUIO - PTY
2 stops7h 30mAvianca
Deal found 10/20$383
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:55 amPTY - UIO
1 stop6h 00mAvianca
Wed 12/175:05 amUIO - PTY
1 stop8h 55mAvianca
Deal found 10/21$394
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:48 amPTY - UIO
Nonstop2h 03mCopa Airlines
Tue 1/66:33 pmUIO - PTY
Nonstop1h 55mCopa Airlines
Deal found 10/23$443

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Ecuador that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Panama City to Ecuador that are best for you.

Fly from

Panama City

Fly to

Ecuador

Route

Depart

Return

Price

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Thu 11/20

5:55 pm-11:35 pm

1 stop5h 40m

Guayaquil Jose Joaquin de Olmedo

Mon 12/1

4:40 am-4:55 pm

1 stop12h 15m

$324

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sun 1/11

2:55 am-9:15 am

1 stop6h 20m

Guayaquil Jose Joaquin de Olmedo

Thu 1/15

6:55 pm-1:00 am

1 stop6h 05m

$330

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Thu 12/4

2:55 am-9:15 am

1 stop6h 20m

Guayaquil Jose Joaquin de Olmedo

Thu 12/11

3:30 am-2:00 pm

1 stop10h 30m

$330

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Wed 11/26

5:55 pm-1:05 am

1 stop7h 10m

Guayaquil Jose Joaquin de Olmedo

Sun 11/30

3:30 am-8:50 am

1 stop5h 20m

$330

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Tue 12/9

2:55 am-9:15 am

1 stop6h 20m

Guayaquil Jose Joaquin de Olmedo

Tue 1/6

6:55 pm-1:00 am

1 stop6h 05m

$341

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sun 11/23

2:55 am-12:35 pm

2 stops9h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 12/3

10:25 am-4:55 pm

1 stop6h 30m

$344

Panama CityQuito

PTY - UIO

PTYUIO

Panama City Tocumen Intl

Fri 1/16

5:50 pm-1:20 am

1 stop7h 30m

Quito Mariscal Sucr

Sun 1/18

4:40 pm-1:00 am

2 stops8h 20m

$345

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Thu 11/20

9:02 am-11:18 am

Nonstop2h 16m

Guayaquil Jose Joaquin de Olmedo

Tue 12/2

6:34 pm-8:41 pm

Nonstop2h 07m

$348

Panama CityQuito

PTY - UIO

PTYUIO

Panama City Tocumen Intl

Sun 12/14

2:55 am-8:55 am

1 stop6h 00m

Quito Mariscal Sucr

Sun 1/11

3:55 pm-1:00 am

2 stops9h 05m

$383

Panama CityQuito

PTY - UIO

PTYUIO

Panama City Tocumen Intl

Sat 12/20

9:10 am-11:14 am

Nonstop2h 04m

Quito Mariscal Sucr

Sun 1/4

12:27 pm-2:23 pm

Nonstop1h 56m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Showing 1-10 of 47 results
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Best time to book a flight from Panama City to Ecuador

Have a flexible travel schedule? Discover the best time to fly to Ecuador from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Ecuador

What is the cheapest month to book a flight from Panama City to Ecuador?

Currently, May is the cheapest month in which you can book a flight from Panama City to Ecuador (average of $122). Flying from Panama City to Ecuador in January is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to EC?

Find hourly flight availability from Panama City to Ecuador. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

It’s typically best to fly out from Panama City to Ecuador in the morning. Doing so could potentially save you 24% on the flight price compared to flying in the evening, which is usually more expensive.

Weekly flight availability from Panama City to Ecuador

Explore weekly flight availability from Panama City to Ecuador. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 23, 2025.

The most flights from PTY to EC0 are scheduled on a Thursday (10 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (5 on average).

Reviews of airlines servicing Ecuador

Get insights into the airlines that provide service to Ecuador. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ecuador. Reviews last updated October 23, 2025.
See what other customers who have flown with Copa Airlines and Avianca from Panama City to Ecuador have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,560 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Crew

8.1

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,560 reviews
Copa Airlines
7.6
Good
1,560 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Crew

8.1

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,460 reviews
Copa Airlines
7.6
Good
1,560 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Crew

8.1

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama City to Ecuador. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Ecuador?

    For a flight from Panama City to Ecuador, you will be flying from Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • How long is the flight from Panama City to Ecuador?

    For as low as $393, Avianca can have you in Ecuador from Panama City in 2h 04m. Panama City and Ecuador are separated by a distance of 639 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City to Ecuador?

    Most travelers choose Panama City Tocumen Intl - Guayaquil Jose Joaquin de Olmedo, Panama City Tocumen Intl - Quito Mariscal Sucr or Panama City Tocumen Intl - Baltra when deciding on the best route from Panama City to Ecuador.

  • What are the most reliable airlines from Panama City to Ecuador?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama City to Ecuador on time: Copa Airlines (90%), Turkish Airlines (88%), Air France (87%).

  • What are the cheapest flights from Panama City to Ecuador?

    On average you can expect to pay $448 for a flight from Panama City to Ecuador. The cheapest flight overall is $393 while the most popular route, (Panama City Tocumen Intl - Guayaquil Jose Joaquin de Olmedo) is currently priced at $339.

  • Can I find deals for flights from Panama City to Ecuador that include hotel bookings?

    Yes. In addition to deals on Panama City to Ecuador flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Ecuador?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Ecuador.

  • Can I find deals for business class flights from Panama City to Ecuador?

    Yes. Cheapflights offers flight deals from Panama City to Ecuador by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Ecuador?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Ecuador (average of $122). Flying from Panama City to Ecuador in January is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Ecuador

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Ecuador

Discover the top 2 airlines that operate flights from Panama City to Ecuador. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$232Average$335FlexibilityNo cancel feeOn-time70%
AviancaCheapest$232Average$337FlexibilityNo cancel feeOn-time71%

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