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Ecuador

$171+ Cheap flights from Panama City (PTY) to Ecuador

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — UIO
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Panama City to Ecuador

Keep the following information in mind while searching for Panama City to Ecuador flight deals. Data was last updated September 17, 2025.

Round-trip from

$275
(Avianca)

One-way from

$171
(Priceline)

Popular in

March

Cheapest in

February

Average price

$317

Good round-trip deal

$347 or less
From Panama City Tocumen Intl to Ecuador
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One-way flight from Panama City Tocumen Intl to Ecuador
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Highest demand for flights based on searches. 3% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Ecuador.
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Find flight deals from Panama City to Ecuador

Cheapest flights from Panama City to Ecuador
Explore the most affordable flight options available from Panama City to Ecuador. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/183:20 amPTY - UIO
2 stops10h 00mAvianca
Sun 9/213:55 pmUIO - PTY
2 stops8h 15mAvianca
Deal found 9/15$302
This Priceline deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:55 amPTY - GYE
1 stop11h 30mAvianca
Thu 11/139:05 amGYE - PTY
1 stop4h 55mAvianca
Deal found 9/17$330
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:20 amPTY - GYE
1 stop5h 15mAvianca
Wed 10/13:35 amGYE - PTY
1 stop5h 20mAvianca
Deal found 9/17$332
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/13:20 amPTY - UIO
1 stop29h 15mAvianca
Sun 10/53:55 pmUIO - PTY
2 stops8h 15mAvianca
Deal found 9/17$347
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:19 amPTY - GYE
Nonstop2h 17mCopa Airlines
Wed 11/56:02 amGYE - PTY
Nonstop2h 10mCopa Airlines
Deal found 9/17$348
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:20 amPTY - GYE
2 stops9h 05mAvianca
Thu 10/99:45 amGYE - PTY
1 stop11h 25mAvianca
Deal found 9/17$350
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/219:55 amPTY - GYE
2 stops7h 45mAvianca
Mon 11/33:30 amGYE - PTY
1 stop5h 20mAvianca
Deal found 9/16$351
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/162:55 amPTY - UIO
1 stop10h 15mAvianca
Mon 11/173:55 pmUIO - PTY
2 stops8h 45mAvianca
Deal found 9/17$353
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:27 pmPTY - GYE
Nonstop2h 16mCopa Airlines
Thu 1/14:33 amGYE - PTY
Nonstop2h 08mCopa Airlines
Deal found 9/16$355
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:55 amPTY - UIO
1 stop10h 15mAvianca
Wed 12/244:40 pmUIO - PTY
2 stops8h 00mAvianca
Deal found 9/15$357
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:40 pmPTY - GYE
Nonstop2h 13mCopa Airlines
Sun 11/94:31 amGYE - PTY
Nonstop2h 08mCopa Airlines
Deal found 9/16$373
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:27 pmPTY - GYE
Nonstop2h 16mCopa Airlines
Thu 1/812:20 pmGYE - PTY
Nonstop2h 08mCopa Airlines
Deal found 9/17$375

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Ecuador that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama City to Ecuador that are best for you.

Fly from

Panama City

Fly to

Ecuador

Route

Depart

Return

Price

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Tue 11/11

2:55 am-2:25 pm

1 stop11h 30m

Guayaquil Jose Joaquin de Olmedo

Thu 11/13

9:05 am-2:00 pm

1 stop4h 55m

$330

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Wed 10/1

11:00 am-5:20 pm

1 stop6h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 10/1

3:35 am-8:55 am

1 stop5h 20m

$332

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sat 11/1

6:27 pm-8:43 pm

Nonstop2h 16m

Guayaquil Jose Joaquin de Olmedo

Wed 11/5

6:02 am-8:12 am

Nonstop2h 10m

$348

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Mon 12/22

9:40 pm-11:57 pm

Nonstop2h 17m

Guayaquil Jose Joaquin de Olmedo

Mon 12/29

12:20 pm-2:32 pm

Nonstop2h 12m

$348

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Thu 10/16

11:31 am-1:46 pm

Nonstop2h 15m

Guayaquil Jose Joaquin de Olmedo

Thu 10/23

2:54 pm-5:05 pm

Nonstop2h 11m

$348

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sat 11/1

11:19 am-1:36 pm

Nonstop2h 17m

Guayaquil Jose Joaquin de Olmedo

Sun 11/16

12:21 pm-2:32 pm

Nonstop2h 11m

$348

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Thu 12/18

9:40 pm-11:57 pm

Nonstop2h 17m

Guayaquil Jose Joaquin de Olmedo

Fri 1/16

4:33 am-6:41 am

Nonstop2h 08m

$348

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Wed 1/7

11:17 am-1:34 pm

Nonstop2h 17m

Guayaquil Jose Joaquin de Olmedo

Sat 1/17

12:20 pm-2:28 pm

Nonstop2h 08m

$348

Panama CityQuito

PTY - UIO

PTYUIO

Panama City Tocumen Intl

Sun 11/16

2:55 am-1:10 pm

1 stop10h 15m

Quito Mariscal Sucr

Mon 11/17

3:55 pm-12:40 am

2 stops8h 45m

$353

Panama CityQuito

PTY - UIO

PTYUIO

Panama City Tocumen Intl

Sun 12/21

2:55 am-1:10 pm

1 stop10h 15m

Quito Mariscal Sucr

Wed 12/24

4:40 pm-12:40 am

2 stops8h 00m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 39 results
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Best time to book a flight from Panama City to Ecuador

Have a flexible travel schedule? Discover the best time to fly to Ecuador from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Ecuador

What is the cheapest month to book a flight from Panama City to Ecuador?

Currently, April is the cheapest month in which you can book a flight from Panama City to Ecuador (average of $463). Flying from Panama City to Ecuador in December is currently the most expensive (average of $791). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to EC?

Find hourly flight availability from Panama City to Ecuador. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s typically best to fly out from Panama City to Ecuador in the morning. Doing so could potentially save you 13% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Panama City to Ecuador

Explore weekly flight availability from Panama City to Ecuador. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from PTY to EC0 are scheduled on a Monday (10 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (9 on average).

Reviews of airlines servicing Ecuador

Get insights into the airlines that provide service to Ecuador. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ecuador. Reviews last updated September 17, 2025.
See what other customers who have flown with Copa Airlines and Avianca from Panama City to Ecuador have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Comfort

7.4

Overall

7.6

Crew

8.1

Boarding

7.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,533 reviews
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Comfort

7.4

Overall

7.6

Crew

8.1

Boarding

7.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Comfort

7.4

Overall

7.6

Crew

8.1

Boarding

7.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama City to Ecuador. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Ecuador?

    For a flight from Panama City to Ecuador, you will be flying from Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • How long is the flight from Panama City to Ecuador?

    For as low as $389, Avianca can have you in Ecuador from Panama City in 2h 03m. Panama City and Ecuador are separated by a distance of 639 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City to Ecuador?

    Most travelers choose Panama City Tocumen Intl - Quito Mariscal Sucr, Panama City Tocumen Intl - Guayaquil Jose Joaquin de Olmedo or Panama City Tocumen Intl - Baltra when deciding on the best route from Panama City to Ecuador.

  • What are the most reliable airlines from Panama City to Ecuador?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama City to Ecuador on time: Air France (88%), KLM (88%), Turkish Airlines (87%).

  • What are the cheapest flights from Panama City to Ecuador?

    On average you can expect to pay $421 for a flight from Panama City to Ecuador. The cheapest flight overall is $421 while the most popular route, (Panama City Tocumen Intl - Quito Mariscal Sucr) is currently priced at $439.

  • Can I find deals for flights from Panama City to Ecuador that include hotel bookings?

    Yes. In addition to deals on Panama City to Ecuador flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Ecuador?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Ecuador.

  • Can I find deals for business class flights from Panama City to Ecuador?

    Yes. Cheapflights offers flight deals from Panama City to Ecuador by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Ecuador?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Ecuador (average of $463). Flying from Panama City to Ecuador in December is currently the most expensive (average of $791). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Ecuador

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Ecuador

Discover the top 2 airlines that operate flights from Panama City to Ecuador. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$232Average$325FlexibilityNo cancel feeOn-time70%
AviancaCheapest$232Average$333FlexibilityNo cancel feeOn-time71%

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