HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cuzco

$285+ Cheap flights from Panama City (PTY) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CUZ
Jul 12 — Jul 191
Sat 7/12
Sat 7/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Cuzco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 7, 2025.

Round-trip from

$391
(Avianca)

One-way from

$285

Popular in

August

Cheapest in

February

Average price

$417
From Panama City Tocumen Intl to Cusco Velazco Astete
Search Deals
One-way flight from Panama City Tocumen Intl to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Panama City to Cuzco

Cheapest flights from Panama City to Cuzco
Explore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2025.

This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:55 pmPTY - CUZ
1 stop16h 20mAvianca
Sun 11/23:25 pmCUZ - PTY
1 stop8h 55mAvianca
Deal found 7/7$386
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/173:20 amPTY - CUZ
1 stop7h 40mMultiple Airlines
Sat 8/2311:27 pmCUZ - PTY
2 stops10h 43mMultiple Airlines
Deal found 7/6$502

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Panama City

Fly to

Cuzco

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 10/30

9:55 pm-2:15 pm

1 stop16h 20m

Cusco Velazco Astete

Sun 11/2

3:25 pm-12:20 am

1 stop8h 55m

$386

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 8/17

3:20 am-11:00 am

1 stop7h 40m

Cusco Velazco Astete

Sat 8/23

11:27 pm-10:10 am

2 stops10h 43m

$502

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 8/26

3:20 am-11:00 am

1 stop7h 40m

$285

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/5

Best time to book a flight from Panama City to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cusco

How far ahead should I book a flight from Panama City to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Cuzco. Price data was last updated on June 27, 2025.

Booking 67 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Cusco?

Currently, February is the cheapest month in which you can book a flight from Panama City to Cusco (average of $789). Flying from Panama City to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated July 7, 2025.
Read through reviews of airlines operating flights from Panama City to Cusco, such as Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.7
Okay
2,369 reviews

Comfort

6.3

Boarding

7.0

Crew

7.2

Food

5.1

Entertainment

5.4

Overall

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

GYE - GPS

We could not take this flight… Avianca did not bring us to Guayaquil on time to take it Very bad company
Avianca
6.7
Okay
2,369 reviews
Avianca
6.7
Okay
2,369 reviews

Comfort

6.3

Boarding

7.0

Crew

7.2

Food

5.1

Entertainment

5.4

Overall

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

GYE - GPS

We could not take this flight… Avianca did not bring us to Guayaquil on time to take it Very bad company

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Panama City to Cusco round-trip?

    Currently priced at $391, Avianca will fly you from Panama City to Cusco and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Avianca is currently priced 1% below the average price you’ll pay for this route.

  • Can I find deals for flights from Panama City to Cuzco that include hotel bookings?

    Yes. In addition to deals on Panama City to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cuzco.

  • Can I find deals for business class flights from Panama City to Cuzco?

    Yes. Cheapflights offers flight deals from Panama City to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cusco?

    Currently, February is the cheapest month in which you can book a flight from Panama City to Cusco (average of $789). Flying from Panama City to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Lima flights

Top airline flying from Panama City to Cuzco

Discover the top airline that operate flights from Panama City to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$358Average$436FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.