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Durham

Cheap flights from La Crosse (LSE) to Durham, NC

LSE — RDU
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Find flight deals from La Crosse to Durham

Keep the following information in mind while searching for La Crosse to Durham flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Popular in

June

Cheapest in

August

Average price

$507
Provider with most accurate pricing for La Crosse-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for La Crosse-Raleigh-Durham flights.
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Highest demand for flights based on searches. 31% potential increase in price ($276 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($65 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Insights

Everything you need to know about your flight from La Crosse to Durham

What is the cheapest month to book a flight from La Crosse to Durham?

Currently, May is the cheapest month in which you can book a flight from La Crosse to Durham (average of $228). Flying from La Crosse to Durham in February is currently the most expensive (average of $1,629). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated December 18, 2025.
See what other customers who have flown with American Airlines from La Crosse to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,055 reviews

Overall

7.2

Boarding

7.5

Crew

8.0

Comfort

7.2

Food

6.5

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,055 reviews
American Airlines
7.2
Good
11,055 reviews

Overall

7.2

Boarding

7.5

Crew

8.0

Comfort

7.2

Food

6.5

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to Durham?

    Located just 5.4 mi from the city center, La Crosse is the airport most travelers will use when flying to Durham from La Crosse. Booking flights from La Crosse (LSE) to Durham should be relatively easy as there are 0 daily outbound flights to Durham from 1 airline.

  • Can I find deals for flights from La Crosse to Durham that include hotel bookings?

    Yes. In addition to deals on La Crosse to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Durham.

  • Can I find deals for business class flights from La Crosse to Durham?

    Yes. Cheapflights offers flight deals from La Crosse to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to Durham?

    Currently, May is the cheapest month in which you can book a flight from La Crosse to Durham (average of $228). Flying from La Crosse to Durham in February is currently the most expensive (average of $1,629). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from La Crosse to Durham

Discover the top airline that operate flights from La Crosse to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$410Average$507FlexibilityNo cancel feeOn-time71%

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