$246+ Cheap flights from Florence, SC to Detroit (FLO - DTT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTT
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from Florence to Detroit with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Detroit
Cheapest
Best
Last-minute
One-way
Cheapest flights from Florence to DetroitExplore the most affordable flight options available from Florence to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from Florence to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:22 pm -
1 stop4h 22m
Mon 9/76:43 pm -
1 stop4h 16m
Deal found 8/5![American Airlines logo]()
$558
Best flights from Florence to DetroitDiscover carefully curated flight deals from Florence to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from Florence to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:22 pm -
1 stop4h 22m
Mon 9/76:43 pm -
1 stop4h 16m
Deal found 8/5![American Airlines logo]()
$558
Last-minute flights from Florence to DetroitDiscover last-minute flight deals from Florence to Detroit. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Detroit. Data last updated August 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:22 pm -
1 stop4h 22m
Mon 9/76:43 pm -
1 stop4h 16m
Deal found 8/5![American Airlines logo]()
$558
One-way flights from Florence to DetroitSearch for one-way flight options from Florence to Detroit. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from Florence to Detroit. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am -
1 stop3h 47m
Deal found 8/3![American Airlines logo]()
$246
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:24 am -
2 stops12h 39m
Deal found 8/3![American Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
2 stops12h 33m
Deal found 8/3![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:22 am -
2 stops13h 58m
Deal found 8/3![American Airlines logo]()
$458
Find flight deals from Florence to Detroit
Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Detroit (DTT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $558 (American Airlines) |
One-way from | $246 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Florence to Detroit that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
FlorenceDetroit
FLO Florence - DTW Detroit Metropolitan Wayne County
FLODTW
Florence
Tue 9/1
3:22 pm-7:44 pm
1 stop4h 22m
Detroit Metropolitan Wayne County
Mon 9/7
6:43 pm-10:59 pm
1 stop4h 16m
$558
Cheapest one-way
Quickest one-way
FlorenceDetroit
FLO Florence - DTW Detroit Metropolitan Wayne County
FLODTW
Florence
Sun 9/6
9:00 am-12:47 pm
1 stop3h 47m
$246
FlorenceDetroit
FLO Florence - DTW Detroit Metropolitan Wayne County
FLODTW
Florence
Fri 9/11
6:24 am-7:03 pm
2 stops12h 39m
$283
FlorenceDetroit
FLO Florence - DTW Detroit Metropolitan Wayne County
FLODTW
Florence
Sat 9/5
9:00 am-8:13 pm
2 stops11h 13m
$339
FlorenceDetroit
FLO Florence - DTW Detroit Metropolitan Wayne County
FLODTW
Florence
Fri 9/4
6:22 am-8:20 pm
2 stops13h 58m
$458
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Florence, South Carolina-Detroit flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Detroit flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Detroit flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Florence, South Carolina-Detroit flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Detroit flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Florence to Detroit
Have a flexible travel schedule? Discover the best time to fly to Detroit from Florence with our price prediction graph.
FLO-DTT
FLO-DTW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Detroit
FLO-DTT
FLO-DTW
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Florence to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Detroit?
Book flights to Detroit if you plan to visit one of these locationsRoseville
Port Huron
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