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$289+ Cheap flights from Florence, SC to Detroit (FLO - DTT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTT
Apr 3 — Apr 101
Fri 4/3
Fri 4/10
1 adult, Economy
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Cheap flight deals from Florence to Detroit

Cheapest flights from Florence to Detroit
Explore the most affordable flight options available from Florence to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.

This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:20 pm
FLO
-
DTW
1 stop4h 43m
American Airlines
Wed 3/117:55 pm
DTW
-
FLO
1 stop4h 02m
American Airlines
Deal found 3/4$402
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:16 am
FLO
-
DTW
1 stop5h 38m
American Airlines
Mon 3/2311:55 am
DTW
-
FLO
1 stop5h 55m
American Airlines
Deal found 3/3$429
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
FLO
-
DTW
1 stop4h 02m
American Airlines
Thu 3/1911:55 am
DTW
-
FLO
1 stop5h 55m
American Airlines
Deal found 3/4$881

Find flight deals from Florence to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Detroit (DTT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 4, 2026.

Round-trip from

$429
(American Airlines)

One-way from

$289
(American Airlines)
From Florence to Detroit (DTT)
Search Deals
One-way flight from Florence to Detroit (DTT)
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
Use the filters below to find and compare flights from Florence to Detroit that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 3/19

5:16 am-10:54 am

1 stop5h 38m

Detroit Metropolitan Wayne County

Mon 3/23

11:55 am-5:50 pm

1 stop5h 55m

$429

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Tue 3/17

6:15 am-10:17 am

1 stop4h 02m

Detroit Metropolitan Wayne County

Thu 3/19

11:55 am-5:50 pm

1 stop5h 55m

$881

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Sat 3/28

5:16 am-9:26 pm

2 stops16h 10m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/27

Sorted by cheapest first

Best time to book a flight from Florence to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Detroit

What is the cheapest month to book a flight from Florence, South Carolina to Detroit?

Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit (average of $71). Flying from Florence, South Carolina to Detroit in December is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Detroit?

    Departing from Florence, South Carolina to Detroit will take you 5h 38m. Florence, South Carolina and Detroit are separated by a distance of 589 mi.

  • Can I find deals for flights from Florence to Detroit that include hotel bookings?

    Yes. In addition to deals on Florence to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Detroit.

  • Can I find deals for business class flights from Florence to Detroit?

    Yes. Cheapflights offers flight deals from Florence to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Detroit?

    Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit (average of $71). Flying from Florence, South Carolina to Detroit in December is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Roseville
Port Huron

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