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$491+ Cheap flights from Florence, SC to Detroit (FLO - DTT)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTT
ago. 25 — sep. 11
lun. 8/25
lun. 9/1
1 adult, Economy
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Cheap flight deals from Florence to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Detroit (DTT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 20, 2025.

Round-trip from

$491
(American Airlines)
From Florence to Detroit (DTT)
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Find flight deals from Florence to Detroit

Cheapest flights from Florence to Detroit
Explore the most affordable flight options available from Florence to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/73:19 pmFLO - DTW
1 stop6h 09mAmerican Airlines
sáb. 10/116:00 amDTW - FLO
1 stop4h 46mAmerican Airlines
Deal found 8/17$491
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/76:14 amFLO - DTW
1 stop4h 35mAmerican Airlines
dom. 10/127:26 pmDTW - FLO
1 stop4h 37mAmerican Airlines
Deal found 8/17$518
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/95:14 amFLO - DTW
1 stop3h 58mAmerican Airlines
lun. 10/137:10 amDTW - FLO
1 stop6h 54mAmerican Airlines
Deal found 8/17$545
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/95:14 amFLO - DTW
1 stop3h 58mAmerican Airlines
dom. 10/127:00 amDTW - FLO
2 stops7h 04mAmerican Airlines
Deal found 8/17$550
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/115:14 amFLO - DTW
1 stop6h 04mAmerican Airlines
sáb. 10/116:04 pmDTW - FLO
2 stops20h 00mAmerican Airlines
Deal found 8/17$602
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/265:15 amFLO - DTW
1 stop4h 33mAmerican Airlines
dom. 11/307:35 pmDTW - FLO
1 stop4h 28mAmerican Airlines
Deal found 8/18$648

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
Use the filters below to find and compare flights from Florence to Detroit that are best for you.

Fly from

Florence

Fly to

Detroit

Route

Depart

Return

Price

FlorenceDetroit

FLO - DTW

FLODTW

Florence

mié. 10/8

6:14 am-12:07 pm

1 stop5h 53m

Detroit Metropolitan Wayne County

sáb. 10/11

6:00 am-10:46 am

1 stop4h 46m

$491

FlorenceDetroit

FLO - DTW

FLODTW

Florence

mar. 10/7

3:19 pm-9:28 pm

1 stop6h 09m

Detroit Metropolitan Wayne County

sáb. 10/11

6:00 am-10:46 am

1 stop4h 46m

$491

FlorenceDetroit

FLO - DTW

FLODTW

Florence

mar. 10/7

6:14 am-10:49 am

1 stop4h 35m

Detroit Metropolitan Wayne County

lun. 10/13

7:10 am-2:04 pm

1 stop6h 54m

$518

FlorenceDetroit

FLO - DTW

FLODTW

Florence

jue. 10/9

5:14 am-9:12 am

1 stop3h 58m

Detroit Metropolitan Wayne County

sáb. 10/11

6:00 am-10:46 am

1 stop4h 46m

$518

FlorenceDetroit

FLO - DTW

FLODTW

Florence

mié. 10/8

6:14 am-10:43 am

1 stop4h 29m

Detroit Metropolitan Wayne County

dom. 10/12

6:00 am-10:46 am

1 stop4h 46m

$518

FlorenceDetroit

FLO - DTW

FLODTW

Florence

sáb. 10/11

5:14 am-11:18 am

1 stop6h 04m

Detroit Metropolitan Wayne County

lun. 10/13

6:00 am-10:46 am

1 stop4h 46m

$518

FlorenceDetroit

FLO - DTW

FLODTW

Florence

vie. 10/10

11:11 am-3:19 pm

1 stop4h 08m

Detroit Metropolitan Wayne County

sáb. 10/11

7:10 am-2:04 pm

1 stop6h 54m

$518

FlorenceDetroit

FLO - DTW

FLODTW

Florence

mié. 10/8

6:14 am-12:07 pm

1 stop5h 53m

Detroit Metropolitan Wayne County

lun. 10/13

7:10 am-2:04 pm

1 stop6h 54m

$518

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Florence to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Detroit

What is the cheapest month to book a flight from Florence, South Carolina to Detroit?

Currently, April is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit (average of $257). Flying from Florence, South Carolina to Detroit in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Detroit?

    Departing from Florence, South Carolina to Detroit will take you 5h 53m. Florence, South Carolina and Detroit are separated by a distance of 589 mi.

  • Can I find deals for flights from Florence to Detroit that include hotel bookings?

    Yes. In addition to deals on Florence to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Detroit.

  • Can I find deals for business class flights from Florence to Detroit?

    Yes. Cheapflights offers flight deals from Florence to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Detroit?

    Currently, April is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit (average of $257). Flying from Florence, South Carolina to Detroit in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Roseville
Port Huron

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