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Des Moines

$53+ Cheap flights from Wyoming to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAC — DSM
Jun 9 — Jun 161
Tue 6/9
Tue 6/16
1 adult, Economy
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Cheap flight deals from Wyoming to Des Moines

Cheapest flights from Wyoming to Des Moines
Explore the most affordable flight options available from Wyoming to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.

This Super.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:44 am
DEN
-
DSM
Nonstop1h 47m
Frontier
Wed 6/102:16 pm
DSM
-
DEN
Nonstop2h 07m
Frontier
Deal found 5/6$127
This deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:46 am
DEN
-
DSM
Nonstop1h 45m
Frontier
Wed 6/242:16 pm
DSM
-
DEN
Nonstop2h 07m
Frontier
Deal found 5/5$128
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:46 am
DEN
-
DSM
Nonstop1h 45m
Frontier
Mon 8/312:16 pm
DSM
-
DEN
Nonstop2h 07m
Frontier
Deal found 5/7$131
This Super.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:46 am
DEN
-
DSM
Nonstop1h 48m
Frontier
Wed 7/152:19 pm
DSM
-
DEN
Nonstop2h 04m
Frontier
Deal found 5/8$135
This Super.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:46 am
DEN
-
DSM
Nonstop1h 45m
Frontier
Wed 6/172:16 pm
DSM
-
DEN
Nonstop2h 07m
Frontier
Deal found 5/6$141
This Frontier deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:46 am
DEN
-
DSM
Nonstop1h 48m
Frontier
Mon 7/202:19 pm
DSM
-
DEN
Nonstop2h 04m
Frontier
Deal found 5/6$142
This Super.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:46 am
DEN
-
DSM
Nonstop1h 45m
Frontier
Fri 6/192:16 pm
DSM
-
DEN
Nonstop2h 07m
Frontier
Deal found 5/6$151
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:46 am
DEN
-
DSM
Nonstop1h 45m
Frontier
Mon 6/292:26 pm
DSM
-
DEN
Nonstop2h 07m
Frontier
Deal found 5/7$162
This Super.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:46 am
DEN
-
DSM
Nonstop1h 48m
Frontier
Mon 7/132:19 pm
DSM
-
DEN
Nonstop2h 04m
Frontier
Deal found 5/6$164
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:44 am
DEN
-
DSM
Nonstop1h 47m
Frontier
Mon 6/12:16 pm
DSM
-
DEN
Nonstop2h 02m
Frontier
Deal found 5/6$167
This Frontier deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:23 am
SLC
-
DSM
1 stop4h 08m
Frontier
Wed 6/102:16 pm
DSM
-
SLC
1 stop8h 39m
Frontier
Deal found 5/6$210
This Frontier deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:23 am
SLC
-
DSM
1 stop4h 08m
Frontier
Mon 6/82:16 pm
DSM
-
SLC
1 stop8h 43m
Frontier
Deal found 5/7$218

Find flight deals from Wyoming to Des Moines

Keep the following information in mind while searching for Wyoming to Des Moines flight deals. Data was last updated May 10, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$127
(Super.com)

One-way from

$53
(Kiwi.com)
Provider with most accurate pricing for Jackson Hole-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson Hole-Des Moines flights.
Search Deals
From Wyoming to Des Moines
Search Deals
One-way flight from Wyoming to Des Moines
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wyoming to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Wyoming to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 6/10

6:55 pm-9:40 pm

Nonstop1h 45m

Des Moines

Sun 6/14

6:10 am-7:00 am

Nonstop1h 50m

$288

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 10/2

10:30 am-1:10 pm

Nonstop1h 40m

Des Moines

Mon 10/19

5:35 am-10:00 am

1 stop5h 25m

$295

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 6/18

6:00 am-2:05 pm

1 stop7h 05m

Des Moines

Mon 6/22

6:39 pm-12:22 am

1 stop6h 43m

$305
Quickest round-trip

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 10/2

7:55 pm-10:35 pm

Nonstop1h 40m

Des Moines

Sun 10/4

6:35 am-7:25 am

Nonstop1h 50m

$312

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 6/4

7:35 pm-10:20 pm

Nonstop1h 45m

Des Moines

Sat 6/6

5:10 am-8:55 am

1 stop4h 45m

$312

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 8/5

6:00 am-5:11 pm

2 stops10h 11m

Des Moines

Sun 8/9

6:35 pm-12:36 am

1 stop7h 01m

$313

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Mon 6/15

5:35 pm-11:30 pm

1 stop4h 55m

Des Moines

Fri 6/19

4:40 pm-11:05 pm

1 stop7h 25m

$315

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 6/26

5:55 am-11:30 am

1 stop4h 35m

Des Moines

Mon 6/29

4:40 pm-11:40 pm

2 stops8h 00m

$320

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 6/26

7:52 am-10:42 am

Nonstop1h 50m

Des Moines

Sun 6/28

9:14 am-10:20 am

Nonstop2h 06m

$337

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 6/19

5:35 pm-11:30 pm

1 stop4h 55m

Des Moines

Mon 6/22

4:40 pm-11:40 pm

2 stops8h 00m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/10

Showing 1-10 of 49 resultsSorted by cheapest first
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Best time to book a flight from Wyoming to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wyoming with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wyoming to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Wyoming to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Wyoming?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Des Moines from Wyoming.

  • How long is the flight from Wyoming to Des Moines?

    A quick flight from Wyoming to Des Moines can take about 1h 45m. Southwest provides one of the quickest options available for as low as $288. The distance between Wyoming and Des Moines is about 588 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Wyoming to Des Moines?

    Most travelers choose Denver Intl - Des Moines, Salt Lake City - Des Moines or Jackson Hole - Des Moines when deciding on the best route from Wyoming to Des Moines.

  • Can I find deals for flights from Wyoming to Des Moines that include hotel bookings?

    Yes. In addition to deals on Wyoming to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wyoming to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wyoming to Des Moines.

  • Can I find deals for business class flights from Wyoming to Des Moines?

    Yes. Cheapflights offers flight deals from Wyoming to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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Alternative routes for Wyoming to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Reagan-National to Des Moines flights
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