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Des Moines

$32+ Cheap flights from Wyoming to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
JAC — DSM
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from Wyoming to Des Moines

Keep the following information in mind while searching for Wyoming to Des Moines flight deals. Data was last updated October 14, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$83
(Kiwi.com)

One-way from

$32
(Kiwi.com)
Provider with most accurate pricing for Jackson Hole-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Jackson Hole-Des Moines flights.
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From Wyoming to Des Moines
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One-way flight from Wyoming to Des Moines
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Find flight deals from Wyoming to Des Moines

Cheapest flights from Wyoming to Des Moines
Explore the most affordable flight options available from Wyoming to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This Priceline deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:10 amDEN - DSM
Nonstop1h 46mFrontier
Mon 11/102:32 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/14$85
This Frontier deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:03 amDEN - DSM
Nonstop1h 46mFrontier
Sun 11/162:32 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/12$98
This Frontier deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:01 amDEN - DSM
Nonstop1h 46mFrontier
Sun 11/22:32 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/12$111
This Frontier deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:01 amDEN - DSM
Nonstop1h 46mFrontier
Mon 11/32:32 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/12$112
This Frontier deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:23 pmDEN - DSM
Nonstop1h 45mFrontier
Fri 12/128:15 pmDSM - DEN
Nonstop2h 12mFrontier
Deal found 10/13$122
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1911:06 amDEN - DSM
Nonstop1h 46mFrontier
Mon 10/202:39 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/12$123
This Priceline deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1711:06 amDEN - DSM
Nonstop1h 46mFrontier
Mon 10/202:39 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/13$124
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2711:06 amDEN - DSM
Nonstop1h 46mFrontier
Fri 10/312:32 pmDSM - DEN
Nonstop2h 07mFrontier
Deal found 10/12$134
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:04 amDEN - DSM
1 stop23h 11mMultiple Airlines
Sun 11/22:32 pmDSM - DEN
Nonstop2h 07mMultiple Airlines
Deal found 10/12$139
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:10 pmSLC - DSM
1 stop23h 46mFrontier
Sun 11/162:32 pmDSM - SLC
1 stop18h 00mFrontier
Deal found 10/14$144
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:10 pmSLC - DSM
1 stop23h 46mFrontier
Fri 11/142:34 pmDSM - SLC
1 stop10h 27mFrontier
Deal found 10/14$152
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:10 pmSLC - DSM
1 stop16h 39mFrontier
Sun 11/162:32 pmDSM - SLC
1 stop18h 00mFrontier
Deal found 10/13$167

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wyoming to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Wyoming to Des Moines that are best for you.

Fly from

Wyoming

Fly to

Des Moines

Route

Depart

Return

Price

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 10/31

11:01 am-1:47 pm

Nonstop1h 46m

Des Moines

Mon 11/3

2:32 pm-3:39 pm

Nonstop2h 07m

$136

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 11/6

6:47 am-3:33 pm

1 stop7h 46m

Des Moines

Mon 11/10

3:18 pm-9:08 pm

1 stop6h 50m

$177

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 12/5

3:55 pm-9:35 pm

1 stop4h 40m

Des Moines

Fri 12/12

4:10 pm-9:30 pm

1 stop6h 20m

$177

Salt Lake CityDes Moines

SLC - DSM

SLCDSM

Salt Lake City

Thu 11/13

8:10 pm-1:49 pm

1 stop16h 39m

Des Moines

Mon 11/17

2:32 pm-11:40 am

1 stop22h 08m

$184

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Mon 11/10

12:50 am-10:42 am

1 stop8h 52m

Des Moines

Sat 11/15

2:17 pm-8:38 pm

1 stop7h 21m

$197

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 12/4

12:50 am-10:38 am

1 stop8h 48m

Des Moines

Fri 12/12

6:33 pm-12:17 am

1 stop6h 44m

$197

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 11/12

3:14 pm-10:33 pm

1 stop6h 19m

Des Moines

Sat 11/15

6:17 am-3:27 pm

2 stops10h 10m

$202

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Mon 11/10

7:05 am-5:12 pm

2 stops9h 07m

Des Moines

Sat 11/15

11:00 am-3:27 pm

1 stop5h 27m

$202

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 11/5

6:05 am-1:59 pm

1 stop6h 54m

Des Moines

Sat 11/15

11:00 am-7:00 pm

2 stops9h 00m

$202

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 11/6

6:05 am-1:59 pm

1 stop6h 54m

Des Moines

Sat 11/15

11:00 am-7:00 pm

2 stops9h 00m

$202

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 43 results
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Best time to book a flight from Wyoming to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wyoming with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wyoming to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Wyoming to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Wyoming?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Des Moines from Wyoming.

  • How long is the flight from Wyoming to Des Moines?

    A quick flight from Wyoming to Des Moines can take about 1h 46m. Frontier provides one of the quickest options available for as low as $136. The distance between Wyoming and Des Moines is about 588 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Wyoming to Des Moines one-way?

    $79 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Frontier and Delta, with prices starting from $150 and $157, respectively.

  • What are the most popular routes from Wyoming to Des Moines?

    Most travelers choose Denver Intl - Des Moines, Salt Lake City - Des Moines or Jackson Hole - Des Moines when deciding on the best route from Wyoming to Des Moines.

  • Can I find deals for flights from Wyoming to Des Moines that include hotel bookings?

    Yes. In addition to deals on Wyoming to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wyoming to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wyoming to Des Moines.

  • Can I find deals for business class flights from Wyoming to Des Moines?

    Yes. Cheapflights offers flight deals from Wyoming to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Wyoming to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Wyoming to Des Moines

Discover the top airline that operate flights from Wyoming to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$276Average$367FlexibilityNo cancel feeOn-time69%

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