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Des Moines

$28+ Cheap flights from Wyoming to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAC — DSM
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Wyoming to Des Moines

Keep the following information in mind while searching for Wyoming to Des Moines flight deals. Data was last updated January 15, 2026.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$57
(Kiwi.com)

One-way from

$28
(Kiwi.com)
Provider with most accurate pricing for Jackson Hole-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Jackson Hole-Des Moines flights.
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From Wyoming to Des Moines
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One-way flight from Wyoming to Des Moines
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Find flight deals from Wyoming to Des Moines

Cheapest flights from Wyoming to Des Moines
Explore the most affordable flight options available from Wyoming to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:36 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Mon 2/167:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/15$57
This Frontier deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:36 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Sun 2/157:27 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/12$58
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:30 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Mon 3/98:21 pm
DSM
-
DEN
Nonstop2h 05m
Frontier
Deal found 1/13$65
This Super.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:59 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Sun 3/17:27 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/12$79
This Frontier deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:18 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Mon 3/27:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/14$87
This Frontier deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/124:01 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Sun 2/157:27 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/15$96
This Super.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:36 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Fri 2/207:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/14$113
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/124:01 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Mon 2/167:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/15$114
This Frontier deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:49 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Mon 3/27:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/13$119
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:36 pm
DEN
-
DSM
Nonstop1h 43m
Multiple Airlines
Sun 2/159:00 am
DSM
-
DEN
1 stop24h 11m
Multiple Airlines
Deal found 1/15$125
This Frontier deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/129:49 pm
SLC
-
DSM
1 stop19h 30m
Frontier
Thu 2/197:32 pm
DSM
-
SLC
1 stop14h 12m
Frontier
Deal found 1/14$160
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1910:37 pm
SLC
-
DSM
2 stops18h 42m
Frontier
Sun 2/227:45 pm
DSM
-
SLC
1 stop13h 59m
Frontier
Deal found 1/14$218

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wyoming to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Wyoming to Des Moines that are best for you.

Fly from

Wyoming

Fly to

Des Moines

Route

Depart

Return

Price

Salt Lake CityDes Moines

SLC - DSM

SLCDSM

Salt Lake City

Thu 2/12

9:49 pm-6:19 pm

1 stop19h 30m

Des Moines

Thu 2/19

7:32 pm-8:44 am

1 stop14h 12m

$160

Salt Lake CityDes Moines

SLC - DSM

SLCDSM

Salt Lake City

Thu 2/19

10:37 pm-6:19 pm

2 stops18h 42m

Des Moines

Sun 2/22

7:45 pm-8:44 am

1 stop13h 59m

$218

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/13

5:15 pm-11:35 pm

1 stop5h 20m

Des Moines

Fri 2/20

6:10 am-7:15 am

Nonstop2h 05m

$247

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Sat 4/18

5:55 pm-8:55 pm

Nonstop2h 00m

Des Moines

Mon 4/20

5:25 am-12:50 pm

2 stops8h 25m

$271

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/6

6:40 pm-9:20 pm

Nonstop1h 40m

Des Moines

Mon 2/9

4:40 pm-8:00 pm

1 stop4h 20m

$278

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Tue 5/19

12:55 am-10:15 am

2 stops8h 20m

Des Moines

Mon 5/25

2:35 pm-7:58 pm

1 stop6h 23m

$280

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 4/23

7:10 pm-9:55 pm

Nonstop1h 45m

Des Moines

Mon 4/27

5:25 am-12:35 pm

2 stops8h 10m

$281

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 4/17

12:35 am-10:18 am

2 stops8h 43m

Des Moines

Mon 4/20

4:24 pm-12:26 am

2 stops9h 02m

$286

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Sat 5/30

5:55 pm-8:55 pm

Nonstop2h 00m

Des Moines

Sun 5/31

8:40 pm-8:25 am

1 stop12h 45m

$288

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 5/22

1:39 pm-4:14 pm

Nonstop1h 35m

Des Moines

Sun 5/24

5:03 pm-6:01 pm

Nonstop1h 58m

$290

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 39 results
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Best time to book a flight from Wyoming to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wyoming with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wyoming to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Wyoming to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Wyoming?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Des Moines from Wyoming.

  • How long is the flight from Wyoming to Des Moines?

    A quick flight from Wyoming to Des Moines can take about 5h 20m. Frontier provides one of the quickest options available for as low as $247. The distance between Wyoming and Des Moines is about 588 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Wyoming to Des Moines?

    Most travelers choose Denver Intl - Des Moines, Salt Lake City - Des Moines or Jackson Hole - Des Moines when deciding on the best route from Wyoming to Des Moines.

  • Can I find deals for flights from Wyoming to Des Moines that include hotel bookings?

    Yes. In addition to deals on Wyoming to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wyoming to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wyoming to Des Moines.

  • Can I find deals for business class flights from Wyoming to Des Moines?

    Yes. Cheapflights offers flight deals from Wyoming to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Wyoming to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Wyoming to Des Moines

Discover the top airline that operate flights from Wyoming to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$276Average$367FlexibilityNo cancel feeOn-time69%

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