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Des Moines

$28+ Cheap flights from Wyoming to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAC — DSM
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Wyoming to Des Moines

Keep the following information in mind while searching for Wyoming to Des Moines flight deals. Data was last updated November 26, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$91
(Frontier)

One-way from

$28
(Kiwi.com)
Provider with most accurate pricing for Jackson Hole-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Jackson Hole-Des Moines flights.
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From Wyoming to Des Moines
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One-way flight from Wyoming to Des Moines
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Find flight deals from Wyoming to Des Moines

Cheapest flights from Wyoming to Des Moines
Explore the most affordable flight options available from Wyoming to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Frontier deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/84:18 pmDEN - DSM
Nonstop1h 45mFrontier
Mon 12/157:58 pmDSM - DEN
Nonstop2h 11mFrontier
Deal found 11/25$91
This FlightHub deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:18 pmDEN - DSM
Nonstop1h 45mFrontier
Mon 12/157:58 pmDSM - DEN
Nonstop2h 11mFrontier
Deal found 11/24$97
This eDestinos deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:18 pmDEN - DSM
Nonstop1h 45mFrontier
Mon 12/87:58 pmDSM - DEN
Nonstop2h 11mFrontier
Deal found 11/25$110
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:58 pmSLC - DSM
1 stop21h 46mMultiple Airlines
Wed 12/313:00 pmDSM - SLC
1 stop7h 33mMultiple Airlines
Deal found 11/24$272
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:39 amSLC - DSM
2 stops27h 52mMultiple Airlines
Mon 12/87:58 pmDSM - SLC
1 stop16h 39mMultiple Airlines
Deal found 11/23$277
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:20 amSLC - DSM
2 stops30h 34mMultiple Airlines
Sun 12/148:30 amDSM - SLC
1 stop28h 11mMultiple Airlines
Deal found 11/25$284
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:08 pmSLC - DSM
1 stop4h 50mUnited Airlines
Wed 1/75:30 amDSM - SLC
1 stop5h 29mUnited Airlines
Deal found 11/24$301
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:39 amSLC - DSM
1 stop27h 01mMultiple Airlines
Mon 12/87:58 pmDSM - SLC
1 stop16h 39mMultiple Airlines
Deal found 11/23$306
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:32 pmSLC - DSM
1 stop23h 31mMultiple Airlines
Sun 12/147:00 amDSM - SLC
1 stop13h 19mMultiple Airlines
Deal found 11/24$312
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:35 pmSLC - DSM
1 stop10h 03mDelta
Wed 12/1711:01 amDSM - SLC
1 stop6h 39mDelta
Deal found 11/25$317
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:59 amSLC - DSM
2 stops11h 00mAmerican Airlines
Wed 12/175:21 amDSM - SLC
1 stop5h 48mAmerican Airlines
Deal found 11/25$322
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:58 pmSLC - DSM
1 stop15h 42mFrontier
Mon 12/298:29 pmDSM - SLC
1 stop16h 08mFrontier
Deal found 11/23$332

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wyoming to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Wyoming to Des Moines that are best for you.

Fly from

Wyoming

Fly to

Des Moines

Route

Depart

Return

Price

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 1/23

2:30 pm-9:10 pm

1 stop5h 40m

Des Moines

Sun 1/25

6:25 am-7:30 am

Nonstop2h 05m

$215

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 12/10

5:15 pm-7:55 pm

Nonstop1h 40m

Des Moines

Mon 12/15

8:20 am-9:20 am

Nonstop2h 00m

$222

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Sat 12/13

3:14 pm-10:34 pm

1 stop6h 20m

Des Moines

Mon 12/15

6:50 am-12:53 pm

1 stop7h 03m

$241

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Sat 12/13

1:57 pm-9:15 pm

1 stop6h 18m

Des Moines

Wed 12/17

2:59 pm-8:02 pm

1 stop6h 03m

$241

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Sun 12/7

12:50 am-10:38 am

1 stop8h 48m

Des Moines

Tue 12/16

6:50 am-10:07 am

1 stop4h 17m

$242

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Tue 12/9

5:45 am-1:31 pm

1 stop6h 46m

Des Moines

Tue 12/16

11:01 am-3:39 pm

1 stop5h 38m

$242

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Sun 12/7

12:50 am-10:38 am

1 stop8h 48m

Des Moines

Mon 12/15

2:59 pm-7:42 pm

1 stop5h 43m

$242

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Tue 12/9

10:34 am-5:47 pm

1 stop6h 13m

Des Moines

Thu 12/18

6:17 am-2:12 pm

1 stop8h 55m

$284

JacksonDes Moines

JAC - DSM

JACDSM

Jackson Hole

Fri 1/30

4:29 pm-11:44 pm

1 stop6h 15m

Des Moines

Tue 2/3

5:09 pm-8:42 pm

1 stop4h 33m

$299

Salt Lake CityDes Moines

SLC - DSM

SLCDSM

Salt Lake City

Wed 12/31

6:08 pm-11:58 pm

1 stop4h 50m

Des Moines

Wed 1/7

5:30 am-9:59 am

1 stop5h 29m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Showing 1-10 of 40 results
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Best time to book a flight from Wyoming to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wyoming with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wyoming to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Wyoming to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Wyoming?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Des Moines from Wyoming.

  • How long is the flight from Wyoming to Des Moines?

    A quick flight from Wyoming to Des Moines can take about 5h 40m. Southwest provides one of the quickest options available for as low as $215. The distance between Wyoming and Des Moines is about 588 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Wyoming to Des Moines one-way?

    $61 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $63 and $145, respectively.

  • What are the most popular routes from Wyoming to Des Moines?

    Most travelers choose Denver Intl - Des Moines, Salt Lake City - Des Moines or Jackson Hole - Des Moines when deciding on the best route from Wyoming to Des Moines.

  • Can I find deals for flights from Wyoming to Des Moines that include hotel bookings?

    Yes. In addition to deals on Wyoming to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wyoming to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wyoming to Des Moines.

  • Can I find deals for business class flights from Wyoming to Des Moines?

    Yes. Cheapflights offers flight deals from Wyoming to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Wyoming to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Wyoming to Des Moines

Discover the top airline that operate flights from Wyoming to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$276Average$367FlexibilityNo cancel feeOn-time69%

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