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Des Moines

$280+ Cheap flights from Santa Rosa to Des Moines (STS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
STS — DSM
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Santa Rosa to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Santa Rosa (STS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$569
(American Airlines)

One-way from

$280
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$319
From Santa Rosa Sonoma County to Des Moines
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One-way flight from Santa Rosa Sonoma County to Des Moines
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Highest demand for flights based on searches. 10% potential increase in price ($52 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santa Rosa to Des Moines

Cheapest flights from Santa Rosa to Des Moines
Explore the most affordable flight options available from Santa Rosa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:18 pmSTS - DSM
1 stop7h 41mAmerican Airlines
Sat 11/155:00 amDSM - STS
1 stop9h 07mAmerican Airlines
Deal found 9/13$569
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/261:18 pmSTS - DSM
1 stop7h 35mAmerican Airlines
Mon 12/15:10 amDSM - STS
1 stop9h 38mAmerican Airlines
Deal found 9/14$614
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:18 pmSTS - DSM
1 stop7h 35mAmerican Airlines
Tue 12/25:10 amDSM - STS
1 stop9h 38mAmerican Airlines
Deal found 9/14$639
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/294:19 pmSTS - DSM
1 stop5h 59mAmerican Airlines
Fri 10/38:16 amDSM - STS
1 stop6h 13mAmerican Airlines
Deal found 9/14$719
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2712:37 pmSTS - DSM
1 stop26h 54mAmerican Airlines
Mon 12/15:10 amDSM - STS
1 stop9h 38mAmerican Airlines
Deal found 9/14$741

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Rosa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santa Rosa to Des Moines that are best for you.

Fly from

Santa Rosa

Fly to

Des Moines

Route

Depart

Return

Price

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Tue 11/11

12:37 pm-10:59 pm

2 stops8h 22m

Des Moines

Sat 11/15

5:10 am-12:48 pm

1 stop9h 38m

$574

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Wed 11/26

1:18 pm-10:53 pm

1 stop7h 35m

Des Moines

Mon 12/1

5:10 am-12:48 pm

1 stop9h 38m

$614

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Fri 11/28

1:18 pm-10:53 pm

1 stop7h 35m

Des Moines

Tue 12/2

5:10 am-12:48 pm

1 stop9h 38m

$639

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Mon 9/29

12:25 pm-11:13 pm

1 stop8h 48m

Des Moines

Fri 10/3

7:08 am-3:48 pm

2 stops10h 40m

$724

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Thu 11/27

12:37 pm-2:53 pm

2 stops24h 16m

Des Moines

Mon 12/1

5:10 am-12:48 pm

1 stop9h 38m

$746

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Thu 11/27

11:56 am-5:31 pm

2 stops27h 35m

Des Moines

Mon 12/1

1:53 pm-1:29 pm

2 stops25h 36m

$794

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Wed 10/29

12:53 pm-11:16 pm

2 stops8h 23m

$285

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Wed 10/29

2:22 pm-10:37 pm

3 stops54h 15m

$352

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Sun 9/21

4:19 pm-12:18 am

1 stop5h 59m

$480

Santa RosaDes Moines

STS - DSM

STSDSM

Santa Rosa Sonoma County

Sun 9/21

7:00 am-8:21 pm

2 stops11h 21m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
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Best time to book a flight from Santa Rosa to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Rosa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Rosa to Des Moines

What is the cheapest month to book a flight from Santa Rosa to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Santa Rosa to Des Moines (average of $336). Flying from Santa Rosa to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Rosa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Rosa to Des Moines?

    There are many flights that can get you from Santa Rosa to Des Moines in 8h 22m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 1548 mi.

  • Can I find deals for flights from Santa Rosa to Des Moines that include hotel bookings?

    Yes. In addition to deals on Santa Rosa to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Rosa to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Rosa to Des Moines.

  • Can I find deals for business class flights from Santa Rosa to Des Moines?

    Yes. Cheapflights offers flight deals from Santa Rosa to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Rosa to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Santa Rosa to Des Moines (average of $336). Flying from Santa Rosa to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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