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Des Moines

$146+ Cheap flights from Rochester to Des Moines (ROC - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Rochester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$291
(American Airlines)

One-way from

$146
(American Airlines)

Popular in

March

Cheapest in

February

Average price

$496
From Rochester Greater Rochester Intl to Des Moines
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One-way flight from Rochester Greater Rochester Intl to Des Moines
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Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Rochester to Des Moines

Cheapest flights from Rochester to Des Moines
Explore the most affordable flight options available from Rochester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/172:49 pmROC - DSM
1 stop6h 22mAmerican Airlines
Mon 10/206:22 pmDSM - ROC
1 stop4h 55mAmerican Airlines
Deal found 9/10$291
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:32 pmROC - DSM
1 stop4h 35mAmerican Airlines
Sun 12/286:40 pmDSM - ROC
1 stop4h 35mAmerican Airlines
Deal found 9/10$353
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/171:45 pmROC - DSM
2 stops10h 45mSouthwest
Mon 10/205:35 amDSM - ROC
2 stops10h 40mSouthwest
Deal found 9/10$437
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2412:40 pmROC - DSM
1 stop7h 34mDelta
Sat 9/275:12 pmDSM - ROC
1 stop5h 41mDelta
Deal found 9/9$447
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:55 amROC - DSM
2 stops16h 40mSouthwest
Sun 12/285:30 amDSM - ROC
2 stops7h 25mSouthwest
Deal found 9/10$448
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:53 amROC - DSM
2 stops9h 27mUnited Airlines
Sat 9/278:00 amDSM - ROC
1 stop4h 29mUnited Airlines
Deal found 9/9$452
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:00 amROC - DSM
2 stops6h 25mSouthwest
Sat 9/278:35 amDSM - ROC
2 stops9h 45mSouthwest
Deal found 9/9$463
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:45 pmROC - DSM
2 stops25h 45mUnited Airlines
Sun 12/283:14 pmDSM - ROC
1 stop5h 01mUnited Airlines
Deal found 9/10$486
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:32 pmROC - DSM
1 stop4h 35mAmerican Airlines
Mon 12/296:40 pmDSM - ROC
1 stop4h 35mAmerican Airlines
Deal found 9/9$547
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:15 amROC - DSM
1 stop4h 33mDelta
Sun 12/286:15 amDSM - ROC
1 stop4h 09mDelta
Deal found 9/8$582
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:55 pmROC - DSM
2 stops15h 37mUnited Airlines
Mon 10/206:36 pmDSM - ROC
1 stop14h 43mUnited Airlines
Deal found 9/10$609

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Rochester to Des Moines that are best for you.

Fly from

Rochester

Fly to

Des Moines

Route

Depart

Return

Price

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Fri 10/17

2:49 pm-8:11 pm

1 stop6h 22m

Des Moines

Mon 10/20

6:22 pm-12:17 am

1 stop4h 55m

$291

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 12/24

2:32 pm-6:07 pm

1 stop4h 35m

Des Moines

Sun 12/28

6:40 pm-12:15 am

1 stop4h 35m

$353

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Fri 10/17

1:45 pm-11:30 pm

2 stops10h 45m

Des Moines

Mon 10/20

5:35 am-5:15 pm

2 stops10h 40m

$437

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 9/24

12:40 pm-7:14 pm

1 stop7h 34m

Des Moines

Sat 9/27

5:12 pm-11:53 pm

1 stop5h 41m

$447

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 9/24

5:49 pm-11:45 pm

1 stop6h 56m

Des Moines

Sat 9/27

6:00 am-12:41 pm

1 stop5h 41m

$447

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 12/24

5:55 am-9:35 pm

2 stops16h 40m

Des Moines

Sun 12/28

5:30 am-1:55 pm

2 stops7h 25m

$448

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 9/24

5:53 am-2:20 pm

2 stops9h 27m

Des Moines

Sat 9/27

8:00 am-1:29 pm

1 stop4h 29m

$452

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 9/24

6:00 am-11:25 am

2 stops6h 25m

Des Moines

Sat 9/27

8:35 am-7:20 pm

2 stops9h 45m

$463

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Wed 12/24

7:45 pm-8:30 pm

2 stops25h 45m

Des Moines

Sun 12/28

3:14 pm-9:15 pm

1 stop5h 01m

$486

RochesterDes Moines

ROC - DSM

ROCDSM

Rochester Greater Rochester Intl

Fri 12/26

2:32 pm-6:07 pm

1 stop4h 35m

Des Moines

Mon 12/29

6:40 pm-12:15 am

1 stop4h 35m

$547

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 16 results
1
2

Best time to book a flight from Rochester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Des Moines

What is the cheapest month to book a flight from Rochester to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Rochester to Des Moines (average of $336). Flying from Rochester to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROC to DSM?

Find hourly flight availability from Rochester to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Rochester to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 6% versus a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Rochester to Des Moines by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester to Des Moines?

    For as low as $291, American Airlines can have you in Des Moines from Rochester in 6h 22m. The distance from Rochester to Des Moines is about 822 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Rochester to Des Moines round-trip?

    Delta, at $244, was found to be the cheapest airline from Rochester to Des Moines.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 42% lower than the current average price 3 months from now.

  • Can I find deals for flights from Rochester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Rochester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Des Moines.

  • Can I find deals for business class flights from Rochester to Des Moines?

    Yes. Cheapflights offers flight deals from Rochester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Rochester to Des Moines (average of $336). Flying from Rochester to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Rochester to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Rochester to Des Moines

Discover the top 3 airlines that operate flights from Rochester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$244Average$386FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$291Average$386FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$316Average$412FlexibilityNo cancel feeOn-time71%

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