$71+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Mar 15 — Mar 221
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in September or August, booked 68 days in advance, depart on a Tuesday or Monday and return on a Saturday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:41 pm
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Sun 6/73:11 pm
DSM
- PDX
Nonstop3h 43m
Allegiant Air
Deal found 2/12![Allegiant Air logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:04 pm
PDX
- DSM
1 stop29h 12m
Frontier
Sat 3/218:21 pm
DSM
- PDX
1 stop16h 48m
Frontier
Deal found 2/12![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
- DSM
1 stop29h 12m
Frontier
Mon 3/98:21 pm
DSM
- PDX
2 stops38h 37m
Frontier
Deal found 2/12![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Sun 5/313:06 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 2/12![Allegiant Air logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:41 pm
PDX
- DSM
Nonstop3h 14m
Multiple Airlines
Sun 6/79:31 pm
DSM
- PDX
1 stop25h 38m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Wed 5/278:05 pm
DSM
- PDX
1 stop24h 22m
Allegiant Air
Deal found 2/12![Allegiant Air logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
PDX
- DSM
Nonstop3h 18m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- PDX
1 stop24h 43m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:48 am
PDX
- DSM
1 stop23h 41m
Multiple Airlines
Sun 5/1011:00 am
DSM
- PDX
1 stop23h 59m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:48 pm
PDX
- DSM
2 stops30h 43m
Multiple Airlines
Wed 5/278:05 pm
DSM
- PDX
1 stop24h 22m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$343
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
PDX
- DSM
Nonstop3h 18m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- PDX
1 stop24h 43m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:04 pm
PDX
- DSM
2 stops20h 01m
Frontier
Sat 3/218:21 pm
DSM
- PDX
1 stop16h 48m
Frontier
Deal found 2/12![Frontier logo]()
$341
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:30 am
PDX
- DSM
1 stop7h 39m
Delta
Wed 3/254:25 pm
DSM
- PDX
1 stop6h 00m
Delta
Deal found 2/10![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:04 pm
PDX
- DSM
1 stop9h 38m
American Airlines
Thu 4/92:02 pm
DSM
- PDX
1 stop9h 01m
American Airlines
Deal found 2/13![American Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:48 pm
PDX
- DSM
2 stops30h 43m
Multiple Airlines
Wed 5/278:05 pm
DSM
- PDX
1 stop24h 22m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:30 am
PDX
- DSM
1 stop7h 39m
Delta
Wed 3/254:25 pm
DSM
- PDX
1 stop6h 00m
Delta
Deal found 2/10![Delta logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
PDX
- DSM
2 stops22h 37m
Multiple Airlines
Sun 5/1011:00 am
DSM
- PDX
1 stop23h 59m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:15 pm
PDX
- DSM
1 stop8h 31m
Delta
Sat 3/214:25 pm
DSM
- PDX
1 stop6h 00m
Delta
Deal found 2/12![Delta logo]()
$389
This Expedia deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
- DSM
1 stop5h 12m
Multiple Airlines
Mon 3/92:28 pm
DSM
- PDX
1 stop8h 13m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:30 pm
PDX
- DSM
1 stop10h 18m
Delta
Thu 3/1911:33 am
DSM
- PDX
1 stop9h 27m
Delta
Deal found 2/12![Delta logo]()
$402
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:30 pm
PDX
- DSM
1 stop10h 18m
Delta
Sat 3/214:25 pm
DSM
- PDX
1 stop6h 00m
Delta
Deal found 2/12![Delta logo]()
$402
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated February 13, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated February 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:57 pm
PDX
- DSM
1 stop7h 23m
United Airlines
Wed 3/255:30 am
DSM
- PDX
1 stop6h 24m
United Airlines
Deal found 2/10![United Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
- DSM
1 stop29h 12m
Frontier
Mon 3/98:21 pm
DSM
- PDX
2 stops38h 37m
Frontier
Deal found 2/12![Frontier logo]()
$261
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:30 am
PDX
- DSM
1 stop5h 51m
United Airlines
Tue 3/245:30 am
DSM
- PDX
1 stop6h 24m
United Airlines
Deal found 2/11![United Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:04 pm
PDX
- DSM
1 stop29h 12m
Multiple Airlines
Thu 3/193:59 pm
DSM
- PDX
2 stops45h 53m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:04 pm
PDX
- DSM
1 stop29h 12m
Frontier
Sat 3/218:21 pm
DSM
- PDX
1 stop16h 48m
Frontier
Deal found 2/12![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:04 pm
PDX
- DSM
1 stop29h 12m
Multiple Airlines
Fri 3/207:00 am
DSM
- PDX
2 stops28h 28m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:30 am
PDX
- DSM
1 stop7h 39m
Delta
Wed 3/254:25 pm
DSM
- PDX
1 stop6h 00m
Delta
Deal found 2/10![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:46 am
PDX
- DSM
1 stop8h 49m
American Airlines
Thu 4/96:26 pm
DSM
- PDX
1 stop6h 37m
American Airlines
Deal found 2/12![American Airlines logo]()
$370
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Deal found 2/11![Allegiant Air logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:04 pm
PDX
- DSM
1 stop29h 12m
Frontier
Deal found 2/9![Frontier logo]()
$113
This Frontier deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1312:04 pm
PDX
- DSM
1 stop5h 12m
Frontier
Deal found 2/9![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:04 pm
PDX
- DSM
2 stops20h 01m
Frontier
Deal found 2/9![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 2/12![Allegiant Air logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:53 am
PDX
- DSM
2 stops26h 39m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$165
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:15 pm
PDX
- DSM
1 stop8h 31m
Delta
Deal found 2/9![Delta logo]()
$181
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:04 pm
PDX
- DSM
1 stop9h 44m
American Airlines
Deal found 2/10![American Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:56 pm
PDX
- DSM
2 stops21h 20m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:30 am
PDX
- DSM
2 stops11h 10m
United Airlines
Deal found 2/10![United Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/139:53 am
PDX
- DSM
2 stops23h 00m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2912:52 pm
PDX
- DSM
2 stops28h 24m
Frontier
Deal found 2/11![Frontier logo]()
$196
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $189 (Kiwi.com) |
One-way from | $71 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $421 |
Good round-trip deal | $285 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Portland
Fly to
Des Moines
Route
Depart
Return
Price
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 5/28
5:40 pm-10:58 pm
Nonstop3h 18m
Des Moines
Sun 5/31
10:26 pm-9:09 pm
1 stop24h 43m
$324
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Sun 3/15
12:04 pm-10:05 am
2 stops20h 01m
Des Moines
Sat 3/21
8:21 pm-11:09 am
1 stop16h 48m
$341
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 5/20
1:48 pm-10:31 pm
2 stops30h 43m
Des Moines
Wed 5/27
8:05 pm-6:27 pm
1 stop24h 22m
$343
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 3/23
12:30 am-10:09 am
1 stop7h 39m
Des Moines
Wed 3/25
4:25 pm-8:25 pm
1 stop6h 00m
$361
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 3/24
12:30 am-10:09 am
1 stop7h 39m
Des Moines
Wed 3/25
4:25 pm-8:25 pm
1 stop6h 00m
$361
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 3/31
12:04 pm-11:42 pm
1 stop9h 38m
Des Moines
Thu 4/9
2:02 pm-9:03 pm
1 stop9h 01m
$364
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 5/7
12:52 pm-1:29 pm
2 stops22h 37m
Des Moines
Sun 5/10
11:00 am-8:59 am
1 stop23h 59m
$385
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 3/17
11:15 pm-9:46 am
1 stop8h 31m
Des Moines
Sat 3/21
4:25 pm-8:25 pm
1 stop6h 00m
$389
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 3/6
12:04 pm-7:16 pm
1 stop5h 12m
Des Moines
Mon 3/9
2:28 pm-8:41 pm
1 stop8h 13m
$394
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 3/16
10:30 pm-10:48 am
1 stop10h 18m
Des Moines
Thu 3/19
11:33 am-7:00 pm
1 stop9h 27m
$402
Showing 1-10 of 23 results
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Des Moines. Price data was last updated on February 6, 2026.
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 67 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, September is the cheapest month in which you can book a flight from Portland to Des Moines (average of $71). Flying from Portland to Des Moines in November is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 13, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Portland
Popular flights
Alternative routes for Portland to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 13, 2026.
Search flights from Portland to Des Moines by cabin class
Find flights from Portland to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Des Moines flights
Browse other Portland and Des Moines flight options. Last updated on February 13, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on February 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 6 airlines flying from Portland to Des Moines
Discover the top 6 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$81 | Average$193 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$140 | Average$238 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$143 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$251 | Average$474 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$261 | Average$410 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$364 | Average$522 | FlexibilityNo cancel fee | On-time63% |