$147+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Oct 18 — Oct 251
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in October or July, booked 42 days in advance, depart on a Wednesday or Tuesday and return on a Thursday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:44 pm -
1 stop5h 16m
Tue 10/206:55 am -
1 stop7h 43m
Deal found 9/15![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:00 am -
1 stop5h 28m
Sat 12/126:15 am -
2 stops9h 01m
Deal found 9/15![United Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:40 am -
2 stops8h 20m
Sat 12/127:00 am -
2 stops9h 35m
Deal found 9/15![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:27 pm -
1 stop7h 08m
Mon 10/195:22 pm -
1 stop7h 31m
Deal found 9/17![United Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:02 pm -
2 stops18h 23m
Mon 11/28:30 pm -
1 stop16h 37m
Deal found 9/15![Multiple Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:00 am -
1 stop5h 31m
Tue 10/201:27 pm -
2 stops9h 33m
Deal found 9/15![United Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:55 pm -
1 stop8h 01m
Tue 10/204:12 pm -
1 stop9h 27m
Deal found 9/15![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:44 pm -
1 stop5h 16m
Thu 10/296:55 am -
1 stop7h 43m
Deal found 9/15![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:15 am -
2 stops10h 05m
Mon 11/27:15 pm -
2 stops8h 05m
Deal found 9/15![Southwest logo]()
$346
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:44 pm -
1 stop5h 16m
Fri 10/303:46 pm -
1 stop6h 16m
Deal found 9/15![Delta logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:31 pm -
1 stop6h 39m
Mon 11/28:30 pm -
1 stop16h 37m
Deal found 9/15![Multiple Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:00 am -
2 stops11h 35m
Fri 11/61:50 pm -
1 stop9h 10m
Deal found 9/17![Southwest logo]()
$360
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:00 am -
1 stop5h 31m
Tue 10/201:27 pm -
2 stops9h 33m
Deal found 9/15![United Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:30 am -
2 stops8h 20m
Tue 10/206:35 pm -
1 stop5h 40m
Deal found 9/13![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:40 am -
1 stop5h 41m
Tue 10/65:45 am -
2 stops8h 20m
Deal found 9/17![United Airlines logo]()
$450
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:10 pm -
2 stops8h 00m
Sun 10/252:15 pm -
1 stop13h 20m
Deal found 9/17![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:05 pm -
1 stop5h 43m
Sun 10/115:45 am -
2 stops8h 20m
Deal found 9/15![United Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop7h 35m
Mon 11/307:15 pm -
1 stop6h 55m
Deal found 9/13![Southwest logo]()
$530
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:29 pm -
2 stops13h 02m
Sun 10/185:45 am -
2 stops10h 42m
Deal found 9/16![United Airlines logo]()
$516
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:05 am -
2 stops8h 30m
Fri 10/92:00 pm -
1 stop13h 25m
Deal found 9/14![Southwest logo]()
$536
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am -
2 stops8h 20m
Thu 10/152:00 pm -
2 stops9h 15m
Deal found 9/15![Southwest logo]()
$543
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:51 am -
2 stops10h 44m
Mon 10/53:11 pm -
1 stop9h 12m
Deal found 9/17![United Airlines logo]()
$555
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated September 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:55 pm -
1 stop8h 01m
Thu 10/156:29 pm -
1 stop7h 26m
Deal found 9/15![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:44 pm -
1 stop5h 16m
Tue 10/206:55 am -
1 stop7h 43m
Deal found 9/15![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:00 am -
1 stop5h 31m
Tue 10/201:27 pm -
2 stops9h 33m
Deal found 9/15![United Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:50 am -
1 stop7h 40m
Tue 10/206:35 pm -
1 stop5h 40m
Deal found 9/13![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:55 pm -
1 stop8h 01m
Tue 10/204:12 pm -
1 stop9h 27m
Deal found 9/15![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:27 pm -
1 stop7h 08m
Mon 10/195:22 pm -
1 stop7h 31m
Deal found 9/17![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:44 pm -
1 stop5h 16m
Thu 10/296:55 am -
1 stop7h 43m
Deal found 9/15![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:44 pm -
1 stop5h 16m
Fri 10/303:46 pm -
1 stop6h 16m
Deal found 9/15![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:51 am -
1 stop7h 09m
Fri 10/303:46 pm -
1 stop6h 16m
Deal found 9/15![Delta logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:02 pm -
2 stops18h 23m
Mon 11/28:30 pm -
1 stop16h 37m
Deal found 9/15![Multiple Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:15 am -
2 stops10h 05m
Mon 11/27:15 pm -
2 stops8h 05m
Deal found 9/15![Southwest logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:31 pm -
1 stop6h 39m
Mon 11/28:30 pm -
1 stop16h 37m
Deal found 9/15![Multiple Airlines logo]()
$359
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/197:30 am -
1 stop8h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$147
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:51 am -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$168
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:15 am -
2 stops10h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$173
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:19 pm -
1 stop9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$176
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:30 pm -
1 stop9h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:30 am -
2 stops9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$193
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1811:49 pm -
1 stop7h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:00 am -
2 stops10h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![United Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:38 pm -
2 stops17h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$220
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:30 pm -
1 stop9h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$226
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:55 pm -
1 stop8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$229
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Delta) |
One-way from | $147 (American Airlines) |
Popular in | March |
Cheapest in | October |
Average price | $415 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 10/29
10:15 am-10:20 pm
2 stops10h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$173
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 11/13
10:30 am-10:05 pm
2 stops9h 35m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Mon 10/12
11:30 pm-10:31 am
1 stop9h 01m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$226
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sun 10/25
10:55 pm-8:56 am
1 stop8h 01m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$229
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 10/23
12:10 pm-10:10 pm
2 stops8h 00m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$234
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Tue 1/19
10:55 am-8:40 pm
2 stops7h 45m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$234
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Mon 1/18
10:35 am-9:20 pm
2 stops8h 45m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$234
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sun 10/11
6:00 am-2:25 pm
1 stop6h 25m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$249
Quickest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sat 1/2
4:28 pm-11:59 pm
1 stop5h 31m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$257
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 9/24
12:38 pm-9:09 am
2 stops18h 31m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$269
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 41 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, October is the cheapest month in which you can book a flight from Portland to Des Moines (average of $323). Flying from Portland to Des Moines in March is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Airfare is typical for this route at the moment.
Portland to Des Moines flights typically cost between $202 and $474 in October.The cheapest round-trip price found within the last 5 days was $293 on Delta (Oct 13-Oct 20).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 18, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
West Des Moines
Boone
Norwalk
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
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Portland and Des Moines flights
Browse other Portland and Des Moines flight options. Last updated on September 18, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Portland to Des Moines
Discover the top 5 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$266 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$238 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$251 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$301 | Average$507 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$346 | Average$482 | FlexibilityNo cancel fee | On-time63% |