$81+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Jul 29 — Aug 51
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in September or August, booked 39 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.
This Super.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 7/193:06 pm
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$196
This Cheapflightsfares deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:42 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:42 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 8/163:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 6/29![Allegiant Air logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:49 pm
PDX
- DSM
2 stops26h 25m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:20 pm
PDX
- DSM
1 stop23h 14m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:16 pm
PDX
- DSM
1 stop18h 18m
Multiple Airlines
Sun 8/163:08 pm
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:20 pm
PDX
- DSM
1 stop23h 14m
Multiple Airlines
Sun 8/163:08 pm
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$295
This CheapOair deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Thu 8/133:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$304
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 29, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 29, 2026.
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:17 am
PDX
- DSM
1 stop7h 01m
United Airlines
Thu 9/31:21 pm
DSM
- PDX
1 stop7h 32m
United Airlines
Deal found 6/28![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:33 am
PDX
- DSM
1 stop7h 40m
Delta
Thu 8/132:45 pm
DSM
- PDX
1 stop7h 32m
Delta
Deal found 6/28![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:00 am
PDX
- DSM
2 stops9h 55m
Southwest
Thu 10/291:50 pm
DSM
- PDX
1 stop7h 10m
Southwest
Deal found 6/25![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
PDX
- DSM
1 stop6h 04m
Delta
Thu 8/2710:59 am
DSM
- PDX
1 stop8h 35m
Delta
Deal found 6/24![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:07 pm
PDX
- DSM
1 stop5h 37m
United Airlines
Mon 9/71:21 pm
DSM
- PDX
1 stop7h 32m
United Airlines
Deal found 6/27![United Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:15 am
PDX
- DSM
2 stops9h 35m
Southwest
Tue 8/182:40 pm
DSM
- PDX
2 stops9h 40m
Southwest
Deal found 6/25![Southwest logo]()
$474
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:02 pm
PDX
- DSM
1 stop9h 24m
United Airlines
Thu 8/271:21 pm
DSM
- PDX
2 stops13h 09m
United Airlines
Deal found 6/24![United Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:00 am
PDX
- DSM
2 stops9h 45m
Southwest
Sun 8/165:40 am
DSM
- PDX
2 stops10h 25m
Southwest
Deal found 6/28![Southwest logo]()
$505
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:02 pm
PDX
- DSM
1 stop9h 24m
United Airlines
Sun 9/61:21 pm
DSM
- PDX
2 stops11h 24m
United Airlines
Deal found 6/28![United Airlines logo]()
$489
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:15 pm
PDX
- DSM
2 stops8h 10m
Southwest
Fri 7/3112:05 pm
DSM
- PDX
2 stops9h 30m
Southwest
Deal found 6/28![Southwest logo]()
$530
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated June 29, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated June 29, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 7/79:00 am
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$333
This Super.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 7/193:06 pm
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:35 pm
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Sun 7/199:33 pm
DSM
- PDX
1 stop21h 21m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:41 pm
PDX
- DSM
1 stop7h 30m
American Airlines
Wed 7/294:48 pm
DSM
- PDX
1 stop10h 07m
American Airlines
Deal found 6/25![American Airlines logo]()
$347
This Booking.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 pm
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Mon 7/272:19 pm
DSM
- PDX
1 stop28h 12m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$315
This Booking.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:20 pm
PDX
- DSM
1 stop23h 14m
Frontier
Mon 7/272:19 pm
DSM
- PDX
1 stop28h 12m
Frontier
Deal found 6/29![Frontier logo]()
$332
This Mytrip deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 pm
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Wed 7/292:19 pm
DSM
- PDX
1 stop28h 32m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$344
This CheapOair deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Thu 8/133:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$304
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 29, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 29, 2026.
This Super.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 6/24![Allegiant Air logo]()
$81
This Super.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$114
This Super.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$134
This CheapOair deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:34 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 6/25![Allegiant Air logo]()
$144
This Super.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:34 pm
PDX
- DSM
1 stop22h 44m
Frontier
Deal found 6/28![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 6/26![Allegiant Air logo]()
$157
This Super.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:16 pm
PDX
- DSM
1 stop18h 18m
Frontier
Deal found 6/25![Frontier logo]()
$158
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:25 pm
PDX
- DSM
1 stop5h 35m
Southwest
Deal found 6/25![Southwest logo]()
$171
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:35 am
PDX
- DSM
1 stop7h 43m
Delta
Deal found 6/26![Delta logo]()
$174
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $196 (Super.com) |
One-way from | $81 (Super.com) |
Popular in | March |
Cheapest in | September |
Average price | $357 |
Good round-trip deal | $178 or less |
Good one-way deal | $151 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 9/1
8:17 am-5:18 pm
1 stop7h 01m
Des Moines
Thu 9/3
1:21 pm-6:53 pm
1 stop7h 32m
$341
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 7/27
12:33 am-10:13 am
1 stop7h 40m
Des Moines
Thu 8/13
2:45 pm-8:17 pm
1 stop7h 32m
$344
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 10/27
9:00 am-8:55 pm
2 stops9h 55m
Des Moines
Thu 10/29
1:50 pm-7:00 pm
1 stop7h 10m
$366
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 8/24
6:00 am-2:04 pm
1 stop6h 04m
Des Moines
Thu 8/27
10:59 am-5:34 pm
1 stop8h 35m
$375
Quickest round-trip
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 9/4
4:07 pm-11:44 pm
1 stop5h 37m
Des Moines
Mon 9/7
1:21 pm-6:53 pm
1 stop7h 32m
$447
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 8/24
11:02 pm-10:26 am
1 stop9h 24m
Des Moines
Thu 8/27
1:21 pm-12:30 am
2 stops13h 09m
$470
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Sun 8/16
11:15 am-10:50 pm
2 stops9h 35m
Des Moines
Tue 8/18
2:40 pm-10:20 pm
2 stops9h 40m
$474
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 9/3
11:02 pm-10:26 am
1 stop9h 24m
Des Moines
Sun 9/6
1:21 pm-10:45 pm
2 stops11h 24m
$489
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Sat 8/8
9:00 am-8:45 pm
2 stops9h 45m
Des Moines
Sun 8/16
5:40 am-2:05 pm
2 stops10h 25m
$505
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 7/23
12:15 pm-10:25 pm
2 stops8h 10m
Des Moines
Fri 7/31
12:05 pm-7:35 pm
2 stops9h 30m
$530
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 38 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, September is the cheapest month in which you can book a flight from Portland to Des Moines (average of $165). Flying from Portland to Des Moines in March is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 29, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Top 5 airlines flying from Portland to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$225 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$218 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$478 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$499 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$422 | Average$496 | FlexibilityNo cancel fee | On-time63% |