$153+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in July or June, booked 42 days in advance, depart on a Wednesday or Tuesday and return on a Thursday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:49 pm -
1 stop7h 18m
Tue 11/173:31 pm -
1 stop8h 39m
Deal found 10/19![American Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:50 pm -
1 stop5h 00m
Thu 12/106:30 pm -
1 stop5h 50m
Deal found 10/19![Southwest logo]()
$306
This WAYA deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:31 pm -
1 stop7h 04m
Mon 11/98:30 pm -
1 stop16h 37m
Deal found 10/15![Multiple Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:34 pm -
1 stop6h 25m
Tue 11/175:30 am -
2 stops8h 52m
Deal found 10/19![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:35 am -
1 stop9h 00m
Wed 12/167:00 am -
1 stop5h 40m
Deal found 10/18![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:35 am -
1 stop7h 44m
Thu 11/262:48 pm -
1 stop7h 11m
Deal found 10/16![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:20 am -
2 stops8h 15m
Sat 12/195:55 pm -
2 stops9h 05m
Deal found 10/19![Southwest logo]()
$402
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:34 pm -
1 stop6h 56m
Thu 11/121:58 pm -
1 stop7h 49m
Deal found 10/15![American Airlines logo]()
$409
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:50 pm -
1 stop5h 00m
Thu 12/106:30 pm -
1 stop5h 50m
Deal found 10/19![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:34 pm -
1 stop6h 25m
Tue 11/175:30 am -
2 stops8h 52m
Deal found 10/19![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:02 pm -
1 stop7h 50m
Wed 12/235:00 am -
1 stop10h 12m
Deal found 10/19![American Airlines logo]()
$456
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1211:55 am -
1 stop7h 29m
Mon 2/157:00 am -
1 stop5h 49m
Deal found 10/18![Delta logo]()
$477
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:15 am -
2 stops8h 30m
Mon 12/143:30 pm -
1 stop9h 50m
Deal found 10/15![Southwest logo]()
$414
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:34 pm -
1 stop6h 25m
Mon 11/95:09 pm -
2 stops9h 45m
Deal found 10/15![United Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:15 am -
1 stop6h 28m
Sat 12/127:14 am -
1 stop7h 23m
Deal found 10/18![American Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:00 am -
1 stop10h 15m
Fri 1/17:00 am -
2 stops8h 25m
Deal found 10/15![Southwest logo]()
$455
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:00 am -
1 stop10h 00m
Fri 1/17:00 am -
2 stops8h 25m
Deal found 10/16![Southwest logo]()
$465
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:40 am -
1 stop7h 10m
Mon 11/237:15 pm -
2 stops8h 10m
Deal found 10/17![Southwest logo]()
$482
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated October 20, 2026 and is based on user searches.
This WAYA deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:31 pm -
1 stop7h 04m
Mon 11/98:30 pm -
1 stop16h 37m
Deal found 10/15![Multiple Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:34 pm -
1 stop6h 25m
Mon 11/95:09 pm -
2 stops9h 45m
Deal found 10/15![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:20 am -
2 stops8h 45m
Mon 11/97:15 pm -
2 stops8h 10m
Deal found 10/15![Southwest logo]()
$464
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:34 pm -
1 stop6h 56m
Thu 11/121:58 pm -
1 stop7h 49m
Deal found 10/15![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:00 am -
1 stop5h 07m
Thu 11/125:09 pm -
2 stops9h 45m
Deal found 10/15![United Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:49 pm -
1 stop7h 18m
Tue 11/173:31 pm -
1 stop8h 39m
Deal found 10/19![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:34 pm -
1 stop6h 25m
Tue 11/175:30 am -
2 stops8h 52m
Deal found 10/19![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:15 am -
2 stops8h 35m
Tue 11/173:30 pm -
2 stops8h 50m
Deal found 10/19![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:40 am -
1 stop7h 10m
Mon 11/237:15 pm -
2 stops8h 10m
Deal found 10/17![Southwest logo]()
$482
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:35 am -
1 stop7h 44m
Thu 11/262:48 pm -
1 stop7h 11m
Deal found 10/16![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop5h 31m
Tue 11/245:09 pm -
1 stop8h 00m
Deal found 10/18![United Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:24 pm -
1 stop7h 12m
Tue 12/15:13 am -
1 stop7h 54m
Deal found 10/18![American Airlines logo]()
$479
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:09 pm -
1 stop7h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:02 pm -
1 stop29h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Frontier logo]()
$155
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 am -
2 stops9h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$158
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:28 pm -
1 stop5h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![United Airlines logo]()
$195
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:00 am -
1 stop10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Southwest logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:25 pm -
1 stop23h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$214
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:00 pm -
2 stops12h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Southwest logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/155:10 pm -
2 stops41h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:10 am -
1 stop11h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![American Airlines logo]()
$232
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:34 pm -
1 stop6h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![United Airlines logo]()
$239
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $305 (American Airlines) |
One-way from | $153 (American Airlines) |
Popular in | March |
Cheapest in | July |
Average price | $596 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 11/12
11:09 pm-8:46 am
1 stop7h 37m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$153
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Wed 11/18
6:30 am-5:50 pm
2 stops9h 20m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$158
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 12/18
5:00 am-5:00 pm
1 stop10h 00m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$210
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Mon 11/16
11:40 am-10:05 pm
2 stops8h 25m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$210
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Tue 12/15
6:10 am-7:10 pm
1 stop11h 00m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$232
Quickest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 11/20
2:34 pm-10:59 pm
1 stop6h 25m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$239
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 12/10
11:20 am-10:05 pm
1 stop8h 45m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$239
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 12/3
1:50 pm-8:50 pm
1 stop5h 00m
Des Moines
Thu 12/10
6:30 pm-10:20 pm
1 stop5h 50m
$306
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Mon 11/16
2:34 pm-10:59 pm
1 stop6h 25m
Des Moines
Tue 11/17
5:30 am-12:22 pm
2 stops8h 52m
$348
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 12/10
10:15 am-8:45 pm
2 stops8h 30m
Des Moines
Mon 12/14
3:30 pm-11:20 pm
1 stop9h 50m
$414
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 41 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, July is the cheapest month in which you can book a flight from Portland to Des Moines (average of $337). Flying from Portland to Des Moines in March is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Airfare is below average for this route at the moment.
Portland to Des Moines flights typically cost between $368 and $590 in November.The cheapest round-trip price found within the last 5 days was $305 on American Airlines (Nov 16-Nov 17).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 20, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Entertainment
7.4
Boarding
8.1
Overall
7.9
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Food
7.0
Entertainment
7.4
Boarding
8.1
Overall
7.9
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Food
7.0
Entertainment
7.4
Boarding
8.1
Overall
7.9
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Food
7.0
Entertainment
7.4
Boarding
8.1
Overall
7.9
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Food
7.0
Entertainment
7.4
Boarding
8.1
Overall
7.9
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Food
7.0
Entertainment
7.4
Boarding
8.1
Overall
7.9
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Top 5 airlines flying from Portland to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$283 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$238 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$317 | Average$509 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$524 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$346 | Average$496 | FlexibilityNo cancel fee | On-time63% |