$41+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
May 10 — May 171
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in September or August, booked 39 days in advance, depart on a Tuesday or Monday and return on a Friday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 7/289:00 am
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 4/6![Allegiant Air logo]()
$171
This Cheapflightsfares deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:41 pm
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Tue 6/99:00 am
DSM
- PDX
Nonstop3h 43m
Allegiant Air
Deal found 4/7![Allegiant Air logo]()
$195
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Sun 5/313:06 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 4/6![Allegiant Air logo]()
$205
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:44 pm
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Thu 6/113:08 pm
DSM
- PDX
Nonstop3h 43m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$221
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 7/123:06 pm
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$229
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:41 pm
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Sun 6/283:11 pm
DSM
- PDX
Nonstop3h 43m
Allegiant Air
Deal found 4/6![Allegiant Air logo]()
$256
This Booking.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:33 am
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Sun 6/283:11 pm
DSM
- PDX
Nonstop3h 43m
Allegiant Air
Deal found 4/7![Allegiant Air logo]()
$257
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
PDX
- DSM
1 stop22h 56m
Frontier
Mon 6/12:16 pm
DSM
- PDX
1 stop28h 45m
Frontier
Deal found 4/8![Frontier logo]()
$261
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:15 am
PDX
- DSM
2 stops8h 00m
Southwest
Sat 5/165:35 am
DSM
- PDX
1 stop9h 00m
Southwest
Deal found 4/5![Southwest logo]()
$387
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:12 pm
PDX
- DSM
1 stop8h 34m
Delta
Thu 5/2111:57 am
DSM
- PDX
1 stop8h 41m
Delta
Deal found 4/5![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:40 pm
PDX
- DSM
1 stop8h 47m
United Airlines
Sun 6/215:50 am
DSM
- PDX
1 stop5h 58m
United Airlines
Deal found 4/8![United Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:15 am
PDX
- DSM
2 stops8h 55m
Southwest
Wed 5/133:15 pm
DSM
- PDX
2 stops9h 45m
Southwest
Deal found 4/8![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:45 am
PDX
- DSM
2 stops9h 10m
Southwest
Tue 5/56:55 am
DSM
- PDX
2 stops8h 45m
Southwest
Deal found 4/5![Southwest logo]()
$437
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:45 pm
PDX
- DSM
2 stops12h 52m
United Airlines
Mon 5/117:05 pm
DSM
- PDX
1 stop6h 50m
United Airlines
Deal found 4/9![United Airlines logo]()
$481
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:30 pm
PDX
- DSM
1 stop10h 00m
Southwest
Sun 6/286:10 pm
DSM
- PDX
2 stops8h 50m
Southwest
Deal found 4/6![Southwest logo]()
$458
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1912:25 pm
PDX
- DSM
2 stops7h 55m
Southwest
Mon 6/224:40 pm
DSM
- PDX
1 stop9h 15m
Southwest
Deal found 4/9![Southwest logo]()
$482
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:00 am
PDX
- DSM
2 stops10h 20m
Southwest
Sun 6/146:10 pm
DSM
- PDX
2 stops8h 50m
Southwest
Deal found 4/6![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:00 am
PDX
- DSM
2 stops10h 20m
Southwest
Fri 7/36:10 am
DSM
- PDX
2 stops7h 25m
Southwest
Deal found 4/7![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:25 pm
PDX
- DSM
2 stops7h 55m
Southwest
Sun 7/126:10 pm
DSM
- PDX
2 stops8h 50m
Southwest
Deal found 4/8![Southwest logo]()
$487
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated April 10, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:48 am
PDX
- DSM
1 stop23h 21m
Frontier
Mon 4/272:04 pm
DSM
- PDX
1 stop23h 48m
Frontier
Deal found 4/8![Frontier logo]()
$317
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:30 am
PDX
- DSM
1 stop7h 46m
Delta
Tue 5/121:04 pm
DSM
- PDX
1 stop6h 11m
Delta
Deal found 4/6![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:52 pm
PDX
- DSM
1 stop8h 07m
American Airlines
Wed 5/135:01 pm
DSM
- PDX
1 stop7h 46m
American Airlines
Deal found 4/8![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:15 pm
PDX
- DSM
1 stop5h 29m
United Airlines
Wed 5/135:30 am
DSM
- PDX
2 stops9h 05m
United Airlines
Deal found 4/8![United Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:47 pm
PDX
- DSM
1 stop6h 39m
American Airlines
Sat 5/1612:03 pm
DSM
- PDX
1 stop6h 56m
American Airlines
Deal found 4/5![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:52 pm
PDX
- DSM
1 stop8h 07m
American Airlines
Mon 5/116:26 pm
DSM
- PDX
1 stop6h 37m
American Airlines
Deal found 4/6![American Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:31 pm
PDX
- DSM
2 stops18h 00m
Multiple Airlines
Thu 5/1411:00 am
DSM
- PDX
1 stop11h 51m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$388
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Sun 5/313:06 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 4/6![Allegiant Air logo]()
$205
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
PDX
- DSM
1 stop22h 56m
Frontier
Mon 6/12:16 pm
DSM
- PDX
1 stop28h 45m
Frontier
Deal found 4/8![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
PDX
- DSM
1 stop22h 56m
Multiple Airlines
Sun 5/313:06 pm
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$301
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$41
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:40 pm
PDX
- DSM
Nonstop3h 18m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$94
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:35 pm
PDX
- DSM
1 stop22h 56m
Frontier
Deal found 4/8![Frontier logo]()
$117
This Booking.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:35 pm
PDX
- DSM
1 stop22h 56m
Frontier
Deal found 4/9![Frontier logo]()
$131
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:48 am
PDX
- DSM
1 stop23h 21m
Frontier
Deal found 4/6![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$139
This Cheapflightsfares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:33 am
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$148
This Booking.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:35 pm
PDX
- DSM
1 stop22h 56m
Frontier
Deal found 4/8![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:44 pm
PDX
- DSM
Nonstop3h 14m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$156
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:26 pm
PDX
- DSM
1 stop23h 05m
Frontier
Deal found 4/6![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:35 pm
PDX
- DSM
2 stops31h 56m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$167
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $171 (Cheapflightsfares) |
One-way from | $41 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $467 |
Good round-trip deal | $194 or less |
Good one-way deal | $85 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 5/6
11:15 am-9:15 pm
2 stops8h 00m
Des Moines
Sat 5/16
5:35 am-12:35 pm
1 stop9h 00m
$387
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 5/6
11:15 am-10:10 pm
2 stops8h 55m
Des Moines
Wed 5/13
3:15 pm-11:00 pm
2 stops9h 45m
$392
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 5/18
11:12 pm-9:46 am
1 stop8h 34m
Des Moines
Thu 5/21
11:57 am-6:38 pm
1 stop8h 41m
$425
Quickest round-trip
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 6/17
11:40 pm-10:27 am
1 stop8h 47m
Des Moines
Sun 6/21
5:50 am-9:48 am
1 stop5h 58m
$429
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 5/1
10:45 am-9:55 pm
2 stops9h 10m
Des Moines
Tue 5/5
6:55 am-1:40 pm
2 stops8h 45m
$437
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 6/25
11:30 pm-11:30 am
1 stop10h 00m
Des Moines
Sun 6/28
6:10 pm-1:00 am
2 stops8h 50m
$458
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 5/6
7:45 pm-10:37 am
2 stops12h 52m
Des Moines
Mon 5/11
7:05 pm-11:55 pm
1 stop6h 50m
$481
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 6/19
12:25 pm-10:20 pm
2 stops7h 55m
Des Moines
Mon 6/22
4:40 pm-11:55 pm
1 stop9h 15m
$482
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 6/12
10:00 am-10:20 pm
2 stops10h 20m
Des Moines
Sun 6/14
6:10 pm-1:00 am
2 stops8h 50m
$487
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 6/26
10:00 am-10:20 pm
2 stops10h 20m
Des Moines
Fri 7/3
6:10 am-11:35 am
2 stops7h 25m
$487
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Des Moines. Price data was last updated on April 3, 2026.
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, September is the cheapest month in which you can book a flight from Portland to Des Moines (average of $71). Flying from Portland to Des Moines in November is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 10, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Ankeny
Boone
West Des Moines
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
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Portland and Des Moines flights
Browse other Portland and Des Moines flight options. Last updated on April 10, 2026.
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Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 6 airlines flying from Portland to Des Moines
Discover the top 6 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$258 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$81 | Average$192 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$143 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$168 | Average$506 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$251 | Average$487 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$261 | Average$447 | FlexibilityNo cancel fee | On-time71% |