$137+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in September or October, booked 19 days in advance, depart on a Wednesday or Tuesday and return on a Thursday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:34 am -
Nonstop3h 21m
Tue 8/189:00 am -
Nonstop3h 44m
Deal found 8/7![Allegiant Air logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:49 pm -
2 stops26h 25m
Tue 8/189:00 am -
Nonstop3h 44m
Deal found 8/9![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:34 pm -
1 stop11h 23m
Mon 10/122:31 pm -
1 stop28h 04m
Deal found 8/6![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:47 pm -
1 stop27h 01m
Mon 8/318:54 pm -
2 stops22h 17m
Deal found 8/6![Multiple Airlines logo]()
$297
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:16 pm -
1 stop18h 18m
Tue 8/189:00 am -
Nonstop3h 44m
Deal found 8/7![Multiple Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:35 pm -
1 stop9h 55m
Mon 10/192:00 pm -
1 stop13h 20m
Deal found 8/9![Southwest logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:34 pm -
1 stop11h 23m
Sun 10/1110:09 pm -
2 stops15h 30m
Deal found 8/6![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:34 pm -
1 stop11h 23m
Sun 10/1810:09 pm -
2 stops15h 30m
Deal found 8/9![Multiple Airlines logo]()
$324
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:25 am -
1 stop6h 45m
Thu 9/173:50 pm -
1 stop9h 20m
Deal found 8/8![Southwest logo]()
$385
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:02 am -
1 stop8h 26m
Mon 9/75:45 am -
1 stop5h 47m
Deal found 8/6![United Airlines logo]()
$403
This KAYAK deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:00 pm -
1 stop6h 59m
Tue 9/154:14 pm -
1 stop9h 09m
Deal found 8/7![American Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:35 pm -
1 stop9h 55m
Mon 10/194:30 pm -
2 stops10h 50m
Deal found 8/9![Southwest logo]()
$387
This KAYAK deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:00 pm -
1 stop6h 59m
Mon 9/146:22 pm -
1 stop7h 01m
Deal found 8/7![American Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:05 am -
1 stop10h 25m
Tue 9/112:30 pm -
1 stop7h 20m
Deal found 8/9![Southwest logo]()
$413
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 am -
2 stops10h 28m
Sun 9/65:45 am -
2 stops8h 15m
Deal found 8/7![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:00 am -
1 stop5h 32m
Sun 9/66:00 am -
2 stops10h 47m
Deal found 8/7![United Airlines logo]()
$465
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:00 am -
2 stops12h 15m
Mon 9/283:50 pm -
1 stop9h 20m
Deal found 8/7![Southwest logo]()
$436
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:25 pm -
1 stop5h 40m
Sun 10/46:45 am -
2 stops9h 50m
Deal found 8/5![Southwest logo]()
$436
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:15 am -
2 stops7h 55m
Fri 9/113:50 pm -
2 stops9h 30m
Deal found 8/5![Southwest logo]()
$463
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated August 10, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:34 am -
Nonstop3h 21m
Tue 8/189:00 am -
Nonstop3h 44m
Deal found 8/7![Allegiant Air logo]()
$247
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:16 pm -
1 stop18h 18m
Tue 8/189:00 am -
Nonstop3h 44m
Deal found 8/7![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:49 pm -
2 stops26h 25m
Tue 8/189:00 am -
Nonstop3h 44m
Deal found 8/9![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:47 pm -
1 stop27h 01m
Mon 8/318:54 pm -
2 stops22h 17m
Deal found 8/6![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:20 pm -
2 stops28h 28m
Sun 8/309:50 pm -
1 stop21h 31m
Deal found 8/9![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:56 pm -
2 stops36h 53m
Sun 9/69:56 pm -
1 stop14h 52m
Deal found 8/8![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:38 pm -
2 stops30h 03m
Thu 9/1711:29 am -
1 stop26h 14m
Deal found 8/8![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:38 pm -
1 stop28h 55m
Sun 9/209:56 pm -
1 stop15h 58m
Deal found 8/8![Multiple Airlines logo]()
$335
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:47 pm -
2 stops20h 11m
Deal found 8/9![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:47 pm -
1 stop20h 09m
Deal found 8/9![Frontier logo]()
$140
This Super.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:20 pm -
1 stop23h 14m
Deal found 8/6![Frontier logo]()
$188
This Super.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2312:20 pm -
1 stop23h 14m
Deal found 8/7![Frontier logo]()
$189
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:58 am -
1 stop9h 27m
Deal found 8/7![American Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:15 am -
2 stops10h 29m
Deal found 8/6![United Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:49 pm -
2 stops26h 25m
Deal found 8/8![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:56 pm -
3 stops36h 42m
Deal found 8/9![Multiple Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:55 pm -
1 stop7h 35m
Deal found 8/7![United Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:24 pm -
1 stop30h 17m
Deal found 8/9![Multiple Airlines logo]()
$214
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (Kiwi.com) |
One-way from | $137 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $354 |
Good round-trip deal | $337 or less |
Good one-way deal | $228 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 9/10
6:25 am-3:10 pm
1 stop6h 45m
Des Moines
Thu 9/17
3:50 pm-11:10 pm
1 stop9h 20m
$385
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Mon 10/12
11:35 pm-11:30 am
1 stop9h 55m
Des Moines
Mon 10/19
4:30 pm-1:20 am
2 stops10h 50m
$387
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 9/4
7:02 am-5:28 pm
1 stop8h 26m
Des Moines
Mon 9/7
5:45 am-9:32 am
1 stop5h 47m
$403
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sun 8/30
6:05 am-6:30 pm
1 stop10h 25m
Des Moines
Tue 9/1
12:30 pm-5:50 pm
1 stop7h 20m
$413
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sun 9/13
3:00 pm-11:59 pm
1 stop6h 59m
Des Moines
Tue 9/15
4:14 pm-11:23 pm
1 stop9h 09m
$419
Quickest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sun 9/13
3:00 pm-11:59 pm
1 stop6h 59m
Des Moines
Mon 9/14
6:22 pm-11:23 pm
1 stop7h 01m
$419
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 9/25
8:00 am-10:15 pm
2 stops12h 15m
Des Moines
Mon 9/28
3:50 pm-11:10 pm
1 stop9h 20m
$436
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Wed 9/30
1:25 pm-9:05 pm
1 stop5h 40m
Des Moines
Sun 10/4
6:45 am-2:35 pm
2 stops9h 50m
$436
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sat 9/5
5:00 am-5:28 pm
2 stops10h 28m
Des Moines
Sun 9/6
5:45 am-12:00 pm
2 stops8h 15m
$456
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 9/4
5:15 am-3:10 pm
2 stops7h 55m
Des Moines
Fri 9/11
3:50 pm-11:20 pm
2 stops9h 30m
$463
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 18 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, September is the cheapest month in which you can book a flight from Portland to Des Moines (average of $270). Flying from Portland to Des Moines in March is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Airfare is typical for this route at the moment.
Portland to Des Moines flights typically cost between $260 and $477 in October.The cheapest round-trip price found within the last 5 days was $291 on Multiple Airlines (Oct 8-Oct 12).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 10, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
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Portland and Des Moines flights
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Top 5 airlines flying from Portland to Des Moines
Discover the top 5 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$242 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$238 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$346 | Average$482 | FlexibilityNo cancel fee | On-time63% |