$115+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Aug 5 — Aug 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in September or August, booked 33 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.
This CheapOair deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/5![Allegiant Air logo]()
$188
This Booking.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:16 pm
PDX
- DSM
1 stop18h 18m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$219
This Gotogate deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:20 pm
PDX
- DSM
1 stop23h 14m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$254
This CheapOair deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:42 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/3![Allegiant Air logo]()
$267
This Cheapflightsfares deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/49:00 am
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 8/93:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/4![Allegiant Air logo]()
$282
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:42 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 8/163:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$285
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Thu 7/163:06 pm
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$287
This Gotogate deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Wed 8/52:19 pm
DSM
- PDX
1 stop28h 32m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:16 pm
PDX
- DSM
1 stop18h 18m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$301
This Mytrip deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Mon 7/202:19 pm
DSM
- PDX
1 stop28h 12m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$303
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 6, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 6, 2026.
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
PDX
- DSM
1 stop6h 04m
Delta
Thu 8/272:45 pm
DSM
- PDX
1 stop7h 32m
Delta
Deal found 7/1![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:40 am
PDX
- DSM
1 stop5h 39m
United Airlines
Mon 8/315:21 pm
DSM
- PDX
2 stops9h 16m
United Airlines
Deal found 7/1![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:45 am
PDX
- DSM
2 stops11h 00m
Southwest
Wed 8/56:40 pm
DSM
- PDX
1 stop5h 35m
Southwest
Deal found 7/1![Southwest logo]()
$436
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:00 am
PDX
- DSM
2 stops11h 00m
Southwest
Tue 8/256:40 pm
DSM
- PDX
1 stop5h 35m
Southwest
Deal found 7/5![Southwest logo]()
$452
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:07 pm
PDX
- DSM
1 stop5h 37m
United Airlines
Sun 9/66:00 am
DSM
- PDX
2 stops11h 03m
United Airlines
Deal found 7/5![United Airlines logo]()
$492
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:35 am
PDX
- DSM
2 stops9h 10m
Southwest
Tue 8/182:40 pm
DSM
- PDX
2 stops9h 35m
Southwest
Deal found 7/5![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:35 am
PDX
- DSM
2 stops7h 25m
Southwest
Tue 8/182:40 pm
DSM
- PDX
2 stops9h 15m
Southwest
Deal found 7/4![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:35 am
PDX
- DSM
1 stop8h 48m
United Airlines
Sun 8/305:45 am
DSM
- PDX
2 stops11h 02m
United Airlines
Deal found 7/5![United Airlines logo]()
$542
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:50 am
PDX
- DSM
1 stop5h 00m
Southwest
Fri 8/73:50 pm
DSM
- PDX
2 stops9h 25m
Southwest
Deal found 7/2![Southwest logo]()
$498
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:00 am
PDX
- DSM
1 stop5h 32m
United Airlines
Sat 8/298:00 am
DSM
- PDX
2 stops11h 50m
United Airlines
Deal found 7/1![United Airlines logo]()
$548
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:40 am
PDX
- DSM
2 stops9h 05m
Southwest
Tue 8/112:40 pm
DSM
- PDX
2 stops9h 15m
Southwest
Deal found 7/4![Southwest logo]()
$503
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated July 6, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated July 6, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Thu 7/163:06 pm
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$287
This Gotogate deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Wed 8/52:19 pm
DSM
- PDX
1 stop28h 32m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$296
This Mytrip deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Multiple Airlines
Mon 7/202:19 pm
DSM
- PDX
1 stop28h 12m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$303
This Cheapflightsfares deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/49:00 am
DSM
- PDX
Nonstop3h 39m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$274
This CheapOair deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/5![Allegiant Air logo]()
$188
This Booking.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:16 pm
PDX
- DSM
1 stop18h 18m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 8/93:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/4![Allegiant Air logo]()
$282
This Gotogate deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:20 pm
PDX
- DSM
1 stop23h 14m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$254
This CheapOair deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:42 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/3![Allegiant Air logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:16 pm
PDX
- DSM
1 stop18h 18m
Multiple Airlines
Tue 8/189:00 am
DSM
- PDX
Nonstop3h 44m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$301
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:42 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Sun 8/163:08 pm
DSM
- PDX
Nonstop3h 44m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$285
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 6, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 6, 2026.
This Super.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$115
This Booking.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:16 pm
PDX
- DSM
1 stop18h 18m
Frontier
Deal found 7/1![Frontier logo]()
$131
This Super.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:29 am
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 7/2![Allegiant Air logo]()
$146
This Mytrip deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:22 pm
PDX
- DSM
1 stop20h 34m
Frontier
Deal found 7/5![Frontier logo]()
$155
This Super.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:16 pm
PDX
- DSM
1 stop18h 18m
Frontier
Deal found 7/6![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 pm
PDX
- DSM
Nonstop3h 21m
Allegiant Air
Deal found 7/2![Allegiant Air logo]()
$168
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:35 am
PDX
- DSM
1 stop7h 43m
Delta
Deal found 7/2![Delta logo]()
$174
This Booking.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:20 pm
PDX
- DSM
1 stop23h 14m
Frontier
Deal found 7/2![Frontier logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 pm
PDX
- DSM
2 stops15h 27m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:49 pm
PDX
- DSM
2 stops26h 25m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$185
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $188 (CheapOair) |
One-way from | $115 (Super.com) |
Popular in | March |
Cheapest in | September |
Average price | $302 |
Good round-trip deal | $221 or less |
Good one-way deal | $158 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 8/24
6:00 am-2:04 pm
1 stop6h 04m
Des Moines
Thu 8/27
2:45 pm-8:17 pm
1 stop7h 32m
$375
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Mon 8/24
8:40 am-4:19 pm
1 stop5h 39m
Des Moines
Mon 8/31
5:21 pm-12:37 am
2 stops9h 16m
$380
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 7/29
8:45 am-9:45 pm
2 stops11h 00m
Des Moines
Wed 8/5
6:40 pm-10:15 pm
1 stop5h 35m
$436
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 8/19
8:00 am-9:00 pm
2 stops11h 00m
Des Moines
Tue 8/25
6:40 pm-10:15 pm
1 stop5h 35m
$452
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 8/4
6:35 am-5:45 pm
2 stops9h 10m
Des Moines
Tue 8/18
2:40 pm-10:15 pm
2 stops9h 35m
$457
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Tue 8/11
11:35 am-9:00 pm
2 stops7h 25m
Des Moines
Tue 8/18
2:40 pm-9:55 pm
2 stops9h 15m
$457
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 9/3
4:07 pm-11:44 pm
1 stop5h 37m
Des Moines
Sun 9/6
6:00 am-3:03 pm
2 stops11h 03m
$492
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Fri 7/31
5:50 am-12:50 pm
1 stop5h 00m
Des Moines
Fri 8/7
3:50 pm-11:15 pm
2 stops9h 25m
$498
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Wed 7/29
10:40 am-9:45 pm
2 stops9h 05m
Des Moines
Tue 8/11
2:40 pm-9:55 pm
2 stops9h 15m
$503
PortlandDes Moines
PDX - DSM
PDXDSM
Portland
Thu 8/27
10:35 am-9:23 pm
1 stop8h 48m
Des Moines
Sun 8/30
5:45 am-2:47 pm
2 stops11h 02m
$542
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 32 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, September is the cheapest month in which you can book a flight from Portland to Des Moines (average of $168). Flying from Portland to Des Moines in March is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 6, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Portland
Popular flights
Alternative routes for Portland to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 6, 2026.
Search flights from Portland to Des Moines by cabin class
Find flights from Portland to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Des Moines flights
Browse other Portland and Des Moines flight options. Last updated on July 6, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on July 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Portland to Des Moines
Discover the top 5 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$233 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$218 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$251 | Average$478 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$495 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$422 | Average$496 | FlexibilityNo cancel fee | On-time63% |