$147+ Cheap flights from Portland to Des Moines (PDX - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — DSM
Nov 12 — Nov 191
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Des Moines are usually found in July or June, booked 42 days in advance, depart on a Wednesday or Tuesday and return on a Thursday
Cheap flight deals from Portland to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Des MoinesExplore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:30 pm -
1 stop9h 03m
Wed 12/163:31 pm -
1 stop8h 30m
Deal found 10/8![American Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 am -
2 stops9h 20m
Wed 12/166:30 pm -
1 stop5h 45m
Deal found 10/8![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:47 am -
1 stop9h 08m
Wed 11/115:30 am -
1 stop6h 06m
Deal found 10/12![United Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 08m
Wed 11/187:55 pm -
1 stop5h 51m
Deal found 10/12![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:34 pm -
1 stop6h 25m
Tue 11/105:30 am -
2 stops8h 52m
Deal found 10/9![United Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
2 stops23h 03m
Mon 11/239:31 pm -
1 stop22h 03m
Deal found 10/12![Multiple Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:35 am -
1 stop7h 44m
Thu 11/262:48 pm -
1 stop7h 11m
Deal found 10/12![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:00 am -
2 stops11h 35m
Tue 11/107:00 am -
2 stops10h 35m
Deal found 10/9![Southwest logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:31 pm -
1 stop7h 25m
Mon 11/239:31 pm -
1 stop22h 03m
Deal found 10/12![Multiple Airlines logo]()
$399
Best flights from Portland to Des MoinesDiscover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
Discover carefully curated flight deals from Portland to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 am -
2 stops9h 20m
Wed 12/167:00 am -
2 stops8h 25m
Deal found 10/8![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:35 am -
1 stop7h 44m
Tue 11/246:45 am -
1 stop19h 01m
Deal found 10/12![Delta logo]()
$520
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:00 am -
1 stop10h 15m
Fri 1/17:00 am -
2 stops8h 25m
Deal found 10/11![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:20 am -
2 stops8h 40m
Sat 1/25:55 pm -
2 stops9h 25m
Deal found 10/12![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop10h 00m
Fri 11/277:15 pm -
2 stops8h 10m
Deal found 10/13![Southwest logo]()
$523
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:15 pm -
2 stops12h 35m
Fri 11/277:15 pm -
2 stops8h 10m
Deal found 10/12![Southwest logo]()
$545
Last-minute flights from Portland to Des MoinesDiscover last-minute flight deals from Portland to Des Moines. Data last updated October 13, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Des Moines. Data last updated October 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:34 pm -
1 stop6h 25m
Tue 11/105:30 am -
2 stops8h 52m
Deal found 10/9![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:00 am -
2 stops11h 35m
Tue 11/107:00 am -
2 stops10h 35m
Deal found 10/9![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:47 am -
1 stop9h 08m
Wed 11/115:30 am -
1 stop6h 06m
Deal found 10/12![United Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:20 am -
2 stops11h 30m
Wed 11/117:00 am -
2 stops10h 35m
Deal found 10/12![Southwest logo]()
$416
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 08m
Wed 11/187:55 pm -
1 stop5h 51m
Deal found 10/12![Delta logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
2 stops23h 03m
Mon 11/239:31 pm -
1 stop22h 03m
Deal found 10/12![Multiple Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
2 stops23h 03m
Fri 11/209:31 pm -
1 stop14h 01m
Deal found 10/12![Multiple Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:58 am -
1 stop5h 17m
Fri 11/202:48 pm -
1 stop7h 16m
Deal found 10/12![Delta logo]()
$406
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:31 pm -
1 stop7h 25m
Mon 11/239:31 pm -
1 stop22h 03m
Deal found 10/12![Multiple Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 am -
1 stop11h 25m
Sat 11/215:55 pm -
2 stops9h 30m
Deal found 10/12![Southwest logo]()
$417
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:35 am -
1 stop7h 44m
Thu 11/262:48 pm -
1 stop7h 11m
Deal found 10/12![Delta logo]()
$372
One-way flights from Portland to Des MoinesSearch for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
Search for one-way flight options from Portland to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:58 am -
1 stop5h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Delta logo]()
$147
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:09 pm -
1 stop7h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![American Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:02 pm -
2 stops30h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:15 am -
1 stop6h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![American Airlines logo]()
$180
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:00 am -
2 stops10h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:06 am -
2 stops30h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Frontier logo]()
$191
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:47 am -
1 stop9h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![United Airlines logo]()
$195
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 am -
2 stops10h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![United Airlines logo]()
$198
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
2 stops11h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Southwest logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:31 pm -
1 stop6h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$206
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:50 am -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Southwest logo]()
$215
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:35 pm -
2 stops12h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Delta logo]()
$223
Find flight deals from Portland to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (American Airlines) |
One-way from | $147 (Delta) |
Popular in | March |
Cheapest in | July |
Average price | $369 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 11/19
11:58 am-7:17 pm
1 stop5h 19m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$147
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 11/27
5:15 am-1:39 pm
1 stop6h 24m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 11/26
6:00 am-2:08 pm
1 stop6h 08m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 11/12
11:09 pm-8:46 am
1 stop7h 37m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Thu 11/19
12:02 pm-8:41 pm
2 stops30h 39m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$179
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Wed 11/18
9:00 am-9:55 pm
2 stops10h 55m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$183
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sat 10/31
10:47 am-9:55 pm
1 stop9h 08m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$195
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Wed 12/2
6:30 am-5:50 pm
2 stops9h 20m
Des Moines
Wed 12/16
7:00 am-1:25 pm
2 stops8h 25m
$303
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Sat 12/19
5:00 am-5:15 pm
1 stop10h 15m
Des Moines
Fri 1/1
7:00 am-1:25 pm
2 stops8h 25m
$447
PortlandDes Moines
PDX Portland - DSM Des Moines
PDXDSM
Portland
Fri 12/18
6:20 am-5:00 pm
2 stops8h 40m
Des Moines
Sat 1/2
5:55 pm-1:20 am
2 stops9h 25m
$487
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Portland to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
PDX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Des Moines
How far ahead should I book a flight from Portland to Des Moines?
The price you pay for your flight from Portland to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 41 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland to Des Moines?
Currently, July is the cheapest month in which you can book a flight from Portland to Des Moines (average of $337). Flying from Portland to Des Moines in March is currently the most expensive (average of $729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Des Moines?
Airfare is typical for this route at the moment.
Portland to Des Moines flights typically cost between $245 and $444 in December.The cheapest round-trip price found within the last 5 days was $293 on American Airlines (Dec 2-Dec 16).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 13, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Alternative routes for Portland to Des Moines
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 13, 2026.
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Portland and Des Moines flights
Browse other Portland and Des Moines flight options. Last updated on October 13, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on October 13, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Portland to Des Moines
Discover the top 5 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$283 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$238 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$301 | Average$510 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$478 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$482 | FlexibilityNo cancel fee | On-time63% |