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Des Moines

$595+ Cheap flights from Bruxelles-National (BRU) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Bruxelles-National to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$702
(American Airlines)

One-way from

$595
(Kiwi.com)
From Brussels Bruxelles-National to Des Moines
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One-way flight from Brussels Bruxelles-National to Des Moines
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Find flight deals from Bruxelles-National to Des Moines

Cheapest flights from Bruxelles-National to Des Moines
Explore the most affordable flight options available from Bruxelles-National to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:45 amBRU - DSM
2 stops17h 55mAmerican Airlines
Tue 9/306:12 pmDSM - BRU
2 stops19h 13mAmerican Airlines
Deal found 9/11$702
This Finnair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:05 pmBRU - DSM
2 stops30h 32mMultiple Airlines
Tue 10/149:30 amDSM - BRU
2 stops21h 55mMultiple Airlines
Deal found 9/9$752
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:45 amBRU - DSM
1 stop18h 52mKLM
Tue 9/302:05 pmDSM - BRU
1 stop11h 35mKLM
Deal found 9/11$764
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:45 amBRU - DSM
1 stop18h 52mDelta
Tue 9/306:00 amDSM - BRU
2 stops18h 30mDelta
Deal found 9/11$766
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/410:15 amBRU - DSM
1 stop14h 09mUnited Airlines
Tue 10/143:25 pmDSM - BRU
1 stop10h 35mUnited Airlines
Deal found 9/9$777
This Air Canada deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/42:25 pmBRU - DSM
3 stops28h 54mAir Canada
Tue 10/1411:31 amDSM - BRU
3 stops15h 14mAir Canada
Deal found 9/9$1,285
This Air Canada deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:00 amBRU - DSM
2 stops31h 32mMultiple Airlines
Tue 9/3011:31 amDSM - BRU
3 stops15h 14mMultiple Airlines
Deal found 9/11$1,405
This Flysmarter deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:00 amBRU - DSM
3 stops17h 24mAir Canada
Tue 9/308:00 amDSM - BRU
3 stops17h 05mAir Canada
Deal found 9/11$1,520

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Des Moines that are best for you.

Fly from

Bruxelles-National

Fly to

Des Moines

Route

Depart

Return

Price

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Fri 9/26

10:45 am-9:40 pm

2 stops17h 55m

Des Moines

Tue 9/30

6:12 pm-8:25 pm

2 stops19h 13m

$702

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sat 10/4

7:05 pm-6:37 pm

2 stops30h 32m

Des Moines

Tue 10/14

9:30 am-2:25 pm

2 stops21h 55m

$752

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Fri 9/26

10:45 am-10:37 pm

1 stop18h 52m

Des Moines

Tue 9/30

2:05 pm-8:40 am

1 stop11h 35m

$764

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Fri 9/26

10:45 am-10:37 pm

1 stop18h 52m

Des Moines

Tue 9/30

6:00 am-7:30 am

2 stops18h 30m

$766

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sat 10/4

10:45 am-10:37 pm

2 stops18h 52m

Des Moines

Tue 10/14

2:13 pm-8:40 am

1 stop11h 27m

$766

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sat 10/4

10:15 am-5:24 pm

1 stop14h 09m

Des Moines

Tue 10/14

3:25 pm-9:00 am

1 stop10h 35m

$777

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sat 10/4

2:25 pm-12:19 pm

3 stops28h 54m

Des Moines

Tue 10/14

11:31 am-9:45 am

3 stops15h 14m

$1,285

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Fri 9/26

10:00 am-10:32 am

2 stops31h 32m

Des Moines

Tue 9/30

11:31 am-9:45 am

3 stops15h 14m

$1,405

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Fri 9/26

7:00 am-5:24 pm

3 stops17h 24m

Des Moines

Tue 9/30

8:00 am-8:05 am

3 stops17h 05m

$1,520

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 9/17

10:15 pm-2:40 pm

3 stops47h 25m

$620

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results
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Best time to book a flight from Bruxelles-National to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Brussels Bruxelles-National?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Brussels Bruxelles-National to Des Moines. 0 airlines have flights to Des Moines from Brussels Bruxelles-National on a regular basis. Booking flights from Brussels Bruxelles-National to Des Moines should not be difficult; the airport handles an average of 0 inbound flights from Brussels Bruxelles-National per day.

  • How long is the flight from Brussels Bruxelles-National Airport to Des Moines?

    Departing from Brussels Bruxelles-National Airport to Des Moines will take you 17h 55m. Airlines will cover a distance of 4377 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Bruxelles-National to Des Moines that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Des Moines.

  • Can I find deals for business class flights from Bruxelles-National to Des Moines?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Des Moines (average of $336). Flying from Brussels Bruxelles-National Airport to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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