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Des Moines

$490+ Cheap flights from Bruxelles-National (BRU) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — DSM
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Bruxelles-National to Des Moines

Cheapest flights from Bruxelles-National to Des Moines
Explore the most affordable flight options available from Bruxelles-National to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This KLM deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:45 am
BRU
-
DSM
2 stops17h 04m
KLM
Mon 3/210:57 am
DSM
-
BRU
2 stops16h 13m
KLM
Deal found 1/26$705
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:00 am
BRU
-
DSM
2 stops19h 26m
American Airlines
Sun 9/63:41 pm
DSM
-
BRU
2 stops15h 29m
American Airlines
Deal found 1/25$714
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:15 am
BRU
-
DSM
2 stops18h 19m
American Airlines
Thu 3/1911:17 am
DSM
-
BRU
2 stops17h 33m
American Airlines
Deal found 1/26$717
This KLM deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:00 am
BRU
-
DSM
1 stop18h 38m
KLM
Thu 3/195:20 pm
DSM
-
BRU
1 stop32h 40m
KLM
Deal found 1/26$718
This KLM deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/118:05 am
BRU
-
DSM
2 stops15h 23m
KLM
Sun 2/1510:57 am
DSM
-
BRU
2 stops16h 13m
KLM
Deal found 1/27$722
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:10 pm
BRU
-
DSM
2 stops37h 09m
Iberia
Sun 2/151:38 pm
DSM
-
BRU
2 stops18h 07m
Iberia
Deal found 1/27$806
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:30 am
BRU
-
DSM
2 stops18h 11m
United Airlines
Mon 3/23:24 pm
DSM
-
BRU
1 stop10h 31m
United Airlines
Deal found 1/26$817
This Flightnetwork deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:00 am
BRU
-
DSM
2 stops19h 41m
Lufthansa
Mon 3/211:30 am
DSM
-
BRU
1 stop14h 25m
Lufthansa
Deal found 1/26$823

Find flight deals from Bruxelles-National to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$705
(KLM)

One-way from

$490
(Finnair)
Provider with most accurate pricing for Brussels Bruxelles-National-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Brussels Bruxelles-National-Des Moines flights.
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From Brussels Bruxelles-National to Des Moines
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One-way flight from Brussels Bruxelles-National to Des Moines
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Des Moines that are best for you.

Fly from

Bruxelles-National

Fly to

Des Moines

Route

Depart

Return

Price

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Mon 2/23

10:45 am-8:49 pm

2 stops17h 04m

Des Moines

Mon 3/2

10:57 am-10:10 am

2 stops16h 13m

$705

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Thu 3/12

10:15 am-10:34 pm

2 stops18h 19m

Des Moines

Thu 3/19

11:17 am-10:50 am

2 stops17h 33m

$717

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Thu 3/12

10:00 am-10:38 pm

1 stop18h 38m

Des Moines

Thu 3/19

5:20 pm-8:00 am

1 stop32h 40m

$718

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 2/11

8:05 am-4:28 pm

2 stops15h 23m

Des Moines

Sun 2/15

10:57 am-10:10 am

2 stops16h 13m

$722

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Wed 2/11

12:10 pm-6:19 pm

2 stops37h 09m

Des Moines

Sun 2/15

1:38 pm-2:45 pm

2 stops18h 07m

$806

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Mon 2/23

10:30 am-9:41 pm

2 stops18h 11m

Des Moines

Mon 3/2

3:24 pm-8:55 am

1 stop10h 31m

$817

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Mon 2/23

9:00 am-9:41 pm

2 stops19h 41m

Des Moines

Mon 3/2

11:30 am-8:55 am

1 stop14h 25m

$823

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Thu 3/12

10:00 am-1:23 pm

2 stops33h 23m

Des Moines

Thu 3/19

8:00 am-7:50 am

3 stops17h 50m

$1,027

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Thu 3/12

7:00 am-9:40 pm

3 stops20h 40m

Des Moines

Thu 3/19

8:00 am-7:50 am

3 stops17h 50m

$1,259

BrusselsDes Moines

BRU - DSM

BRUDSM

Brussels Bruxelles-National

Sat 5/2

9:35 pm-1:29 pm

3 stops46h 54m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 14 results
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  • Most accurate provider: When it comes to deals on Brussels Bruxelles-National Airport-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Brussels Bruxelles-National Airport-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Brussels Bruxelles-National Airport-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Brussels Bruxelles-National Airport-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Brussels Bruxelles-National Airport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Bruxelles-National to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Brussels Bruxelles-National?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Brussels Bruxelles-National to Des Moines. 0 airlines have flights to Des Moines from Brussels Bruxelles-National on a regular basis. Booking flights from Brussels Bruxelles-National to Des Moines should not be difficult; the airport handles an average of 0 inbound flights from Brussels Bruxelles-National per day.

  • How long is the flight from Brussels Bruxelles-National Airport to Des Moines?

    Departing from Brussels Bruxelles-National Airport to Des Moines will take you 17h 04m. Airlines will cover a distance of 4377 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Bruxelles-National to Des Moines that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Des Moines.

  • Can I find deals for business class flights from Bruxelles-National to Des Moines?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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