HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$289+ Cheap flights from Missoula to Des Moines (MSO - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missoula to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missoula to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$289
(American Airlines)

Popular in

November

Cheapest in

April

Average price

$388
From Missoula Johnson-Bell Field to Des Moines
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($127 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($63 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Missoula to Des Moines

Cheapest flights from Missoula to Des Moines
Explore the most affordable flight options available from Missoula to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/251:50 pmMSO - DSM
1 stop8h 40mAmerican Airlines
Mon 9/295:10 amDSM - MSO
1 stop8h 50mAmerican Airlines
Deal found 9/10$289
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:33 pmMSO - DSM
1 stop4h 28mDelta
Sun 9/1410:55 amDSM - MSO
1 stop4h 43mDelta
Deal found 9/10$389
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:30 amMSO - DSM
2 stops9h 44mUnited Airlines
Sun 9/1411:34 amDSM - MSO
1 stop5h 35mUnited Airlines
Deal found 9/10$394
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:00 amMSO - DSM
1 stop12h 03mDelta
Mon 10/205:32 pmDSM - MSO
1 stop5h 40mDelta
Deal found 9/10$413
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/139:04 pmMSO - DSM
2 stops39h 48mMultiple Airlines
Mon 10/2012:34 pmDSM - MSO
1 stop23h 35mMultiple Airlines
Deal found 9/10$432
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:20 amMSO - DSM
2 stops10h 16mDelta
Mon 1/54:00 pmDSM - MSO
1 stop5h 17mDelta
Deal found 9/11$464
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:15 pmMSO - DSM
1 stop5h 43mUnited Airlines
Mon 1/55:06 pmDSM - MSO
1 stop5h 35mUnited Airlines
Deal found 9/10$484
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1411:59 amMSO - DSM
1 stop26h 37mAllegiant Air
Mon 10/2012:34 pmDSM - MSO
1 stop23h 35mAllegiant Air
Deal found 9/10$492
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:33 pmMSO - DSM
2 stops22h 50mUnited Airlines
Mon 9/295:13 pmDSM - MSO
1 stop5h 12mUnited Airlines
Deal found 9/10$498

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missoula to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Missoula to Des Moines that are best for you.

Fly from

Missoula

Fly to

Des Moines

Route

Depart

Return

Price

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Thu 9/25

1:50 pm-11:30 pm

1 stop8h 40m

Des Moines

Mon 9/29

5:10 am-1:00 pm

1 stop8h 50m

$289

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Wed 10/15

8:00 am-9:03 pm

1 stop12h 03m

Des Moines

Mon 10/20

5:32 pm-10:12 pm

1 stop5h 40m

$413

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Mon 10/13

9:04 pm-1:52 pm

2 stops39h 48m

Des Moines

Mon 10/20

12:34 pm-11:09 am

1 stop23h 35m

$432

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Tue 12/30

5:20 am-4:36 pm

2 stops10h 16m

Des Moines

Mon 1/5

4:00 pm-8:17 pm

1 stop5h 17m

$464

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Tue 12/30

5:15 pm-11:58 pm

1 stop5h 43m

Des Moines

Mon 1/5

5:06 pm-9:41 pm

1 stop5h 35m

$484

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Tue 10/14

11:59 am-3:36 pm

1 stop26h 37m

Des Moines

Mon 10/20

12:34 pm-11:09 am

1 stop23h 35m

$492

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Thu 9/25

2:33 pm-2:23 pm

2 stops22h 50m

Des Moines

Mon 9/29

5:13 pm-9:25 pm

1 stop5h 12m

$498

MissoulaDes Moines

MSO - DSM

MSODSM

Missoula Johnson-Bell Field

Thu 12/25

1:18 pm-11:30 pm

1 stop9h 12m

Des Moines

Wed 12/31

6:40 pm-12:48 pm

1 stop19h 08m

$538

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Missoula to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to Des Moines

How much does it cost to fly round-trip from Missoula to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2025.
See what other customers who have flown with United Airlines from Missoula to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Missoula to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missoula to Des Moines?

    Airlines like American Airlines and Delta fly from Missoula to Des Moines in about 8h 40m. The time it takes to get you to your destination can typically vary by up to 3h 23m. The distance from Missoula to Des Moines is about 1073 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Missoula to Des Moines round-trip?

    Currently priced at $278, United Airlines will fly you from Missoula to Des Moines and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 44% lower than the current average price 3 months from now.

  • Can I find deals for flights from Missoula to Des Moines that include hotel bookings?

    Yes. In addition to deals on Missoula to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to Des Moines.

  • Can I find deals for business class flights from Missoula to Des Moines?

    Yes. Cheapflights offers flight deals from Missoula to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missoula to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Missoula to Des Moines (average of $336). Flying from Missoula to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missoula to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Missoula to Omaha flights
Bozeman to Cedar Rapids flights
Bozeman to Des Moines flights
Billings to Omaha flights
Missoula to Cedar Rapids flights
Bozeman to Omaha flights
Billings to Des Moines flights
Helena to Omaha flights
Great Falls to Des Moines flights
Bozeman to Moline flights
Billings to Cedar Rapids flights
Kalispell to Cedar Rapids flights
Billings to Moline flights
Kalispell to Omaha flights
Great Falls to Cedar Rapids flights
Missoula to Moline flights
Helena to Moline flights
Helena to Des Moines flights
Helena to Cedar Rapids flights
Great Falls to Omaha flights
Kalispell to Moline flights
Cody to Cedar Rapids flights
Bozeman to Dubuque flights
Kalispell to La Crosse flights
Missoula to Dubuque flights
Missoula to La Crosse flights
Bozeman to La Crosse flights
Bozeman to Waterloo flights

Top airline flying from Missoula to Des Moines

Discover the top airline that operate flights from Missoula to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$459FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.