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Des Moines

$258+ Cheap flights from Mexico to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Mexico to Des Moines

Cheapest flights from Mexico to Des Moines
Explore the most affordable flight options available from Mexico to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Aeromexico deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:01 am
CUN
-
DSM
2 stops11h 26m
Aeromexico
Mon 3/25:24 am
DSM
-
CUN
1 stop14h 47m
Aeromexico
Deal found 1/19$411
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:55 pm
CUN
-
DSM
2 stops28h 46m
United Airlines
Mon 3/29:04 am
DSM
-
CUN
2 stops31h 46m
United Airlines
Deal found 1/20$415
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:08 pm
PVR
-
DSM
1 stop28h 59m
United Airlines
Mon 3/26:55 pm
DSM
-
PVR
1 stop18h 40m
United Airlines
Deal found 1/21$440
This Booking.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:10 am
MEX
-
DSM
1 stop11h 06m
Frontier
Sat 3/148:21 pm
DSM
-
MEX
1 stop21h 44m
Frontier
Deal found 1/21$462
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:55 am
BJX
-
DSM
2 stops15h 46m
United Airlines
Sun 3/16:55 pm
DSM
-
BJX
2 stops16h 59m
United Airlines
Deal found 1/19$513
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:35 pm
GDL
-
DSM
2 stops32h 06m
United Airlines
Sun 3/17:52 am
DSM
-
GDL
1 stop28h 44m
United Airlines
Deal found 1/19$527
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:50 am
MEX
-
DSM
1 stop6h 27m
United Airlines
Sun 3/16:55 pm
DSM
-
MEX
1 stop18h 40m
United Airlines
Deal found 1/20$528
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/710:05 am
MEX
-
DSM
2 stops26h 18m
United Airlines
Sat 3/146:49 pm
DSM
-
MEX
2 stops19h 31m
United Airlines
Deal found 1/21$559
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:30 pm
GDL
-
DSM
1 stop9h 15m
United Airlines
Thu 5/218:00 am
DSM
-
GDL
2 stops30h 34m
United Airlines
Deal found 1/20$569
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:40 pm
PVR
-
DSM
1 stop6h 40m
United Airlines
Fri 2/205:30 am
DSM
-
PVR
1 stop7h 02m
United Airlines
Deal found 1/20$599
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:08 am
CUN
-
DSM
1 stop9h 08m
Multiple Airlines
Fri 3/138:32 pm
DSM
-
CUN
2 stops35h 40m
Multiple Airlines
Deal found 1/20$633
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:36 am
GDL
-
DSM
1 stop11h 59m
American Airlines
Thu 5/214:37 pm
DSM
-
GDL
1 stop19h 19m
American Airlines
Deal found 1/20$658

Find flight deals from Mexico to Des Moines

Keep the following information in mind while searching for Mexico to Des Moines flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$411
(Aeromexico)

One-way from

$258
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$506
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico to Des Moines
Search Deals
One-way flight from Mexico to Des Moines
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Mexico to Des Moines that are best for you.

Fly from

Mexico

Fly to

Des Moines

Route

Depart

Return

Price

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Thu 2/26

6:01 am-4:27 pm

2 stops11h 26m

Des Moines

Mon 3/2

5:24 am-9:11 pm

1 stop14h 47m

$411

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

Thu 2/26

5:55 pm-9:41 pm

2 stops28h 46m

Des Moines

Mon 3/2

9:04 am-5:50 pm

2 stops31h 46m

$415

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

Thu 2/26

3:40 pm-9:41 pm

2 stops30h 01m

Des Moines

Mon 3/2

9:04 am-2:06 pm

1 stop29h 02m

$440

LeónDes Moines

BJX - DSM

BJXDSM

León Del Bajio

Wed 2/25

5:55 am-2:17 pm

1 stop8h 22m

Des Moines

Sun 3/1

2:59 pm-11:54 am

1 stop20h 55m

$513

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Thu 2/26

1:35 pm-9:41 pm

2 stops32h 06m

Des Moines

Sun 3/1

7:52 am-12:36 pm

1 stop28h 44m

$527

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 2/25

3:20 pm-10:20 pm

1 stop7h 00m

Des Moines

Sun 3/1

6:55 pm-1:35 pm

1 stop18h 40m

$528

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 3/7

7:55 pm-6:16 pm

2 stops46h 21m

Des Moines

Sat 3/14

8:21 pm-5:05 pm

1 stop21h 44m

$532

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 3/7

10:05 am-12:23 pm

2 stops26h 18m

Des Moines

Sat 3/14

6:49 pm-1:20 pm

2 stops19h 31m

$559

GuadalajaraDes Moines

GDL - DSM

GDLDSM

Guadalajara Miguel Hidal

Sat 5/2

12:30 pm-10:45 pm

1 stop9h 15m

Des Moines

Thu 5/21

8:00 am-1:34 pm

2 stops30h 34m

$569

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

Fri 2/13

3:40 pm-10:20 pm

1 stop6h 40m

Des Moines

Fri 2/20

5:30 am-12:32 pm

1 stop7h 02m

$599

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 27 results
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Best time to book a flight from Mexico to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Des Moines

What is the cheapest month to book a flight from Mexico to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $402). Flying from Mexico to Des Moines in November is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico?

    If you book a flight to Des Moines from Mexico, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Mexico to Des Moines?

    Airlines like Aeromexico and United Airlines fly from Mexico to Des Moines in about 11h 26m. The time it takes to get you to your destination can typically vary by up to 17h 20m. The distance between Mexico and Des Moines is about 1470 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mexico to Des Moines one-way?

    The cheapest airlines for a one-way flight from Mexico to Des Moines are United Airlines ($203), American Airlines ($217), and Delta ($257).

  • What are the most popular routes from Mexico to Des Moines?

    The most popular flight routes from Mexico to Des Moines are Mexico City Benito Juarez - Des Moines, Cancun - Des Moines and Guadalajara Miguel Hidal - Des Moines.

  • Can I find deals for flights from Mexico to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Des Moines.

  • Can I find deals for business class flights from Mexico to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $402). Flying from Mexico to Des Moines in November is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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