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Des Moines

$270+ Cheap flights from Mexico to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
4月 9 — 4月 161
木 4/9
木 4/16
1 adult, Economy
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Cheap flight deals from Mexico to Des Moines

Cheapest flights from Mexico to Des Moines
Explore the most affordable flight options available from Mexico to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3月 10, 2026.

This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 4/177:51 am
CUN
-
DSM
2 stops15h 26m
United Airlines
月 4/205:30 am
DSM
-
CUN
2 stops8h 48m
United Airlines
Deal found 3/9$386
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 4/2410:25 am
GDL
-
DSM
1 stop9h 59m
Multiple Airlines
金 5/110:14 pm
DSM
-
GDL
1 stop22h 38m
Multiple Airlines
Deal found 3/10$396
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 5/110:25 am
GDL
-
DSM
1 stop9h 59m
Multiple Airlines
日 5/3110:26 pm
DSM
-
GDL
2 stops31h 39m
Multiple Airlines
Deal found 3/8$404
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 4/241:18 pm
PVR
-
DSM
2 stops22h 29m
United Airlines
月 4/277:16 pm
DSM
-
PVR
2 stops16h 54m
United Airlines
Deal found 3/9$451
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/96:20 am
MEX
-
DSM
2 stops14h 46m
Multiple Airlines
月 4/133:32 pm
DSM
-
MEX
1 stop31h 13m
Multiple Airlines
Deal found 3/10$463
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
日 4/198:40 am
MEX
-
DSM
1 stop27h 29m
Multiple Airlines
日 4/267:00 am
DSM
-
MEX
2 stops37h 45m
Multiple Airlines
Deal found 3/6$466
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/238:40 am
MEX
-
DSM
1 stop27h 29m
Multiple Airlines
木 4/302:51 pm
DSM
-
MEX
2 stops27h 39m
Multiple Airlines
Deal found 3/9$500
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
火 5/511:35 am
MEX
-
DSM
1 stop10h 10m
United Airlines
日 5/107:05 pm
DSM
-
MEX
2 stops14h 30m
United Airlines
Deal found 3/8$523
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 8/288:05 am
MEX
-
DSM
1 stop7h 08m
United Airlines
日 8/305:16 pm
DSM
-
MEX
2 stops18h 29m
United Airlines
Deal found 3/9$543
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/168:05 am
MEX
-
DSM
1 stop7h 10m
United Airlines
日 4/193:21 pm
DSM
-
MEX
1 stop22h 24m
United Airlines
Deal found 3/6$548
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/96:40 am
GDL
-
DSM
2 stops16h 02m
United Airlines
月 4/138:20 am
DSM
-
GDL
1 stop6h 14m
United Airlines
Deal found 3/6$556
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
月 4/612:30 pm
GDL
-
DSM
2 stops26h 40m
United Airlines
火 5/122:58 pm
DSM
-
GDL
1 stop7h 36m
United Airlines
Deal found 3/8$558

Find flight deals from Mexico to Des Moines

Keep the following information in mind while searching for Mexico to Des Moines flight deals. Data was last updated 3月 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$386
(United Airlines)

One-way from

$270
(Kiwi.com)

Popular in

April

Cheapest in

February

Average price

$688
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico to Des Moines
Search Deals
One-way flight from Mexico to Des Moines
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($87 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 3月 10, 2026.
Use the filters below to find and compare flights from Mexico to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

金 4/17

3:24 pm-10:43 pm

1 stop7h 19m

Des Moines

月 4/20

8:20 am-7:19 pm

1 stop10h 59m

$386
Quickest round-trip

CancúnDes Moines

CUN - DSM

CUNDSM

Cancun

金 4/17

1:50 pm-10:34 pm

1 stop8h 44m

Des Moines

月 4/20

5:45 am-11:30 am

1 stop5h 45m

$387

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

金 4/24

1:18 pm-10:44 am

2 stops20h 26m

Des Moines

月 4/27

7:16 pm-11:10 am

2 stops16h 54m

$451

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

水 5/6

12:19 pm-9:23 pm

2 stops32h 04m

Des Moines

日 5/10

8:15 am-1:56 pm

1 stop6h 41m

$452

Puerto VallartaDes Moines

PVR - DSM

PVRDSM

Puerto Vallarta Ordaz

火 5/5

12:19 pm-2:24 pm

2 stops25h 05m

Des Moines

日 5/10

5:30 am-12:53 pm

1 stop8h 23m

$452

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

木 4/9

6:20 am-10:06 pm

2 stops14h 46m

Des Moines

月 4/13

3:32 pm-9:45 pm

1 stop31h 13m

$463

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

日 4/19

8:40 am-1:09 pm

1 stop27h 29m

Des Moines

日 4/26

7:00 am-7:45 pm

2 stops37h 45m

$466

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

火 5/5

4:40 pm-10:37 am

2 stops16h 57m

Des Moines

日 5/10

7:05 pm-8:35 am

2 stops14h 30m

$523

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

木 8/27

8:05 am-4:13 pm

1 stop7h 08m

Des Moines

日 8/30

3:24 pm-8:35 am

2 stops18h 11m

$523

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

金 8/28

8:05 am-4:13 pm

1 stop7h 08m

Des Moines

日 8/30

5:16 pm-10:45 am

2 stops18h 29m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Mexico to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Des Moines

What is the cheapest month to book a flight from Mexico to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $402). Flying from Mexico to Des Moines in November is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico?

    If you book a flight to Des Moines from Mexico, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Mexico to Des Moines?

    Airlines like United Airlines, Aeromexico, and American Airlines fly from Mexico to Des Moines in about 7h 19m. The time it takes to get you to your destination can typically vary by up to 20h 50m. The distance between Mexico and Des Moines is about 1470 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mexico to Des Moines one-way?

    The cheapest airlines for a one-way flight from Mexico to Des Moines are United Airlines ($191), American Airlines ($217), and Delta ($356).

  • What are the most popular routes from Mexico to Des Moines?

    The most popular flight routes from Mexico to Des Moines are Mexico City Benito Juarez - Des Moines, León Del Bajio - Des Moines and Guadalajara Miguel Hidal - Des Moines.

  • Can I find deals for flights from Mexico to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Des Moines.

  • Can I find deals for business class flights from Mexico to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Mexico to Des Moines (average of $402). Flying from Mexico to Des Moines in November is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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