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Des Moines

$206+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Mar 29 — Apr 51
Sun 3/29
Sun 4/5
1 adult, Economy
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Cheap flight deals from Manchester to Des Moines

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.

This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:46 am
MHT
-
DSM
1 stop5h 44m
American Airlines
Mon 4/132:16 pm
DSM
-
MHT
1 stop7h 35m
American Airlines
Deal found 2/25$335
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:46 am
MHT
-
DSM
1 stop5h 44m
American Airlines
Mon 5/45:01 pm
DSM
-
MHT
1 stop4h 50m
American Airlines
Deal found 2/23$371
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:00 pm
MHT
-
DSM
1 stop7h 10m
American Airlines
Thu 4/911:09 am
DSM
-
MHT
1 stop5h 02m
American Airlines
Deal found 2/26$380
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:20 am
MHT
-
DSM
1 stop5h 50m
Southwest
Thu 4/95:25 am
DSM
-
MHT
2 stops8h 15m
Southwest
Deal found 2/25$400
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:40 pm
MHT
-
DSM
2 stops7h 25m
Southwest
Mon 5/47:10 pm
DSM
-
MHT
2 stops11h 55m
Southwest
Deal found 2/23$405
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:42 am
MHT
-
DSM
1 stop8h 14m
American Airlines
Mon 7/131:41 pm
DSM
-
MHT
1 stop8h 10m
American Airlines
Deal found 2/23$426
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:00 am
MHT
-
DSM
1 stop6h 54m
American Airlines
Tue 3/316:00 am
DSM
-
MHT
1 stop4h 35m
American Airlines
Deal found 2/26$427
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:00 am
MHT
-
DSM
1 stop6h 54m
American Airlines
Thu 4/27:00 am
DSM
-
MHT
1 stop7h 29m
American Airlines
Deal found 2/26$439
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:00 pm
MHT
-
DSM
1 stop6h 51m
American Airlines
Mon 3/306:00 am
DSM
-
MHT
1 stop4h 35m
American Airlines
Deal found 2/26$461

Find flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$335
(American Airlines)

One-way from

$206
(Kiwi.com)

Popular in

January

Cheapest in

May

Average price

$905
Provider with most accurate pricing for Manchester-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Des Moines flights.
Search Deals
From Manchester to Des Moines
Search Deals
One-way flight from Manchester to Des Moines
Search Deals
Highest demand for flights based on searches. 45% potential increase in price ($507 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($80 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 4/9

12:12 pm-7:33 pm

1 stop8h 21m

Des Moines

Mon 4/13

11:09 am-5:11 pm

1 stop5h 02m

$359

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Mon 4/6

4:00 pm-10:10 pm

1 stop7h 10m

Des Moines

Thu 4/9

11:09 am-5:11 pm

1 stop5h 02m

$383

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 5/1

7:25 am-11:45 am

1 stop5h 20m

Des Moines

Mon 5/4

7:10 pm-8:05 am

2 stops11h 55m

$400

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Mon 4/6

7:20 am-12:10 pm

1 stop5h 50m

Des Moines

Thu 4/9

5:25 am-2:40 pm

2 stops8h 15m

$400

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 7/9

5:42 am-12:56 pm

1 stop8h 14m

Des Moines

Mon 7/13

1:41 pm-10:51 pm

1 stop8h 10m

$426

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Mon 4/6

7:31 pm-2:25 pm

2 stops19h 54m

Des Moines

Thu 4/9

8:04 am-6:56 pm

2 stops9h 52m

$522

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 4/9

7:31 pm-2:15 pm

2 stops19h 44m

Des Moines

Mon 4/13

8:04 am-6:56 pm

2 stops9h 52m

$548

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Wed 3/18

7:25 am-11:40 am

1 stop5h 15m

Des Moines

Sat 3/21

4:35 pm-9:50 pm

1 stop4h 15m

$575

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 3/12

11:23 am-9:36 am

2 stops23h 13m

$206

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 3/12

6:00 am-1:18 pm

1 stop8h 18m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/25

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Manchester to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $92). Flying from Manchester, New Hampshire to Des Moines in February is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 27, 2026.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,357 reviews

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,357 reviews
American Airlines
7.2
Good
11,357 reviews

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Des Moines?

    American Airlines and Southwest can get you from Manchester, New Hampshire to Des Moines in just under 5h 20m. Your travel time can differ by up to 3h 01m. Manchester, New Hampshire and Des Moines are separated by a distance of 1137 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Manchester, New Hampshire to Des Moines round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Des Moines round-trip from $308. American Airlines is currently priced 49% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $92). Flying from Manchester, New Hampshire to Des Moines in February is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Boone
Ames
Clive
West Des Moines

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Manchester to Des Moines

Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$308Average$466FlexibilityNo cancel feeOn-time71%

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