HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$336+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Manchester to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$411
(American Airlines)

Popular in

March

Cheapest in

May

Average price

$406
Provider with most accurate pricing for Manchester-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Des Moines flights.
Search Deals
From Manchester to Des Moines
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($98 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Manchester to Des Moines

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:41 amMHT - DSM
1 stop8h 52mAmerican Airlines
Sun 12/144:07 pmDSM - MHT
1 stop5h 41mAmerican Airlines
Deal found 11/25$412
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:44 amMHT - DSM
1 stop8h 35mAmerican Airlines
Wed 12/175:05 pmDSM - MHT
1 stop5h 46mAmerican Airlines
Deal found 11/25$416
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:32 pmMHT - DSM
2 stops8h 05mUnited Airlines
Wed 12/179:00 amDSM - MHT
2 stops8h 49mUnited Airlines
Deal found 11/24$426
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:32 pmMHT - DSM
2 stops10h 12mUnited Airlines
Sun 12/145:45 amDSM - MHT
2 stops12h 04mUnited Airlines
Deal found 11/25$466
This Southwest deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:50 pmMHT - DSM
2 stops9h 05mSouthwest
Tue 12/236:50 pmDSM - MHT
2 stops12h 20mSouthwest
Deal found 11/26$533
This United Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:32 pmMHT - DSM
2 stops10h 12mUnited Airlines
Mon 12/155:45 amDSM - MHT
2 stops12h 04mUnited Airlines
Deal found 11/26$577
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:32 pmMHT - DSM
2 stops8h 05mUnited Airlines
Sat 12/133:17 pmDSM - MHT
2 stops21h 40mUnited Airlines
Deal found 11/23$689

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Manchester

Fly to

Des Moines

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 1/10

5:30 am-12:46 pm

1 stop8h 16m

Des Moines

Tue 1/13

4:25 pm-11:46 pm

1 stop6h 21m

$336

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 1/10

5:45 am-2:55 pm

2 stops10h 10m

Des Moines

Tue 1/13

8:35 am-8:35 pm

2 stops11h 00m

$346

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 1/9

5:01 pm-10:11 pm

1 stop6h 10m

Des Moines

Sun 1/11

6:00 am-11:35 am

1 stop4h 35m

$407

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 12/13

5:44 am-1:19 pm

1 stop8h 35m

Des Moines

Wed 12/17

5:05 pm-11:51 pm

1 stop5h 46m

$416

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 1/9

2:17 pm-11:44 pm

2 stops10h 27m

Des Moines

Sun 1/11

8:00 am-6:51 pm

2 stops9h 51m

$417

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Wed 2/11

2:17 pm-9:50 pm

2 stops8h 33m

Des Moines

Wed 2/25

8:00 am-6:53 pm

2 stops9h 53m

$425

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 12/13

2:32 pm-9:37 pm

2 stops8h 05m

Des Moines

Wed 12/17

9:00 am-6:49 pm

2 stops8h 49m

$426

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Wed 2/11

2:17 pm-9:50 pm

2 stops8h 33m

Des Moines

Thu 2/26

8:00 am-6:53 pm

2 stops9h 53m

$437

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 2/13

5:20 am-1:09 pm

1 stop8h 49m

Des Moines

Tue 2/24

2:00 pm-11:06 pm

1 stop8h 06m

$451

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 2/12

5:20 am-1:09 pm

1 stop8h 49m

Des Moines

Wed 2/25

2:00 pm-11:06 pm

1 stop8h 06m

$451

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/26

Showing 1-10 of 11 results
1
2

Compare providers for flights from Manchester to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

Currently, November is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $95). Flying from Manchester, New Hampshire to Des Moines in January is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to DSM?

Find hourly flight availability from Manchester to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

One of the essential ways to save on airfare from Manchester, New Hampshire to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 36% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 26, 2025.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Entertainment

6.9

Comfort

7.2

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Entertainment

6.9

Comfort

7.2

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Des Moines?

    American Airlines, Southwest, and United Airlines can get you from Manchester, New Hampshire to Des Moines in just under 8h 16m. Your travel time can differ by up to 2h 11m. Manchester, New Hampshire and Des Moines are separated by a distance of 1137 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Manchester, New Hampshire to Des Moines round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Des Moines round-trip from $316. American Airlines is currently priced 32% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

    Currently, November is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $95). Flying from Manchester, New Hampshire to Des Moines in January is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Manchester to Des Moines

Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$466FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.