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Des Moines

$210+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$333
(Southwest)

One-way from

$234
(American Airlines)

Popular in

March

Cheapest in

May

Average price

$445
From Manchester to Des Moines
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One-way flight from Manchester to Des Moines
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Highest demand for flights based on searches. 15% potential increase in price ($88 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Manchester to Des Moines

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:30 pmMHT - DSM
2 stops12h 05mSouthwest
Tue 12/306:50 pmDSM - MHT
2 stops12h 20mSouthwest
Deal found 9/15$333
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:50 pmMHT - DSM
2 stops9h 05mSouthwest
Tue 12/306:50 pmDSM - MHT
2 stops12h 20mSouthwest
Deal found 9/15$388
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:20 amMHT - DSM
2 stops13h 45mSouthwest
Tue 12/306:50 pmDSM - MHT
2 stops12h 20mSouthwest
Deal found 9/15$393
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:15 pmMHT - DSM
1 stop7h 44mAmerican Airlines
Mon 10/136:07 amDSM - MHT
1 stop5h 15mAmerican Airlines
Deal found 9/16$417
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amMHT - DSM
1 stop7h 24mAmerican Airlines
Mon 11/103:18 pmDSM - MHT
1 stop7h 30mAmerican Airlines
Deal found 9/15$447
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:38 pmMHT - DSM
1 stop6h 52mAmerican Airlines
Sun 10/55:00 amDSM - MHT
1 stop6h 08mAmerican Airlines
Deal found 9/16$467
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:00 amMHT - DSM
2 stops6h 55mSouthwest
Thu 1/16:15 amDSM - MHT
2 stops9h 20mSouthwest
Deal found 9/15$477
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:30 pmMHT - DSM
2 stops10h 25mSouthwest
Mon 12/296:50 pmDSM - MHT
2 stops12h 25mSouthwest
Deal found 9/15$499
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:20 amMHT - DSM
2 stops13h 45mSouthwest
Mon 12/296:50 pmDSM - MHT
2 stops12h 25mSouthwest
Deal found 9/15$504
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:59 pmMHT - DSM
2 stops28h 10mMultiple Airlines
Tue 12/306:41 pmDSM - MHT
1 stop23h 15mMultiple Airlines
Deal found 9/15$514
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:36 pmMHT - DSM
1 stop27h 50mMultiple Airlines
Wed 12/316:15 amDSM - MHT
2 stops34h 04mMultiple Airlines
Deal found 9/15$553
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:36 pmMHT - DSM
1 stop27h 50mMultiple Airlines
Mon 12/298:00 amDSM - MHT
2 stops32h 19mMultiple Airlines
Deal found 9/15$568

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Manchester

Fly to

Des Moines

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 12/18

12:30 pm-11:35 pm

2 stops12h 05m

Des Moines

Tue 12/30

6:50 pm-8:10 am

2 stops12h 20m

$333

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 12/20

5:00 am-10:55 am

2 stops6h 55m

Des Moines

Wed 12/31

6:15 am-7:05 pm

2 stops11h 50m

$388

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 12/20

3:50 pm-11:55 pm

2 stops9h 05m

Des Moines

Tue 12/30

6:50 pm-8:10 am

2 stops12h 20m

$388

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 12/19

11:20 am-12:05 am

2 stops13h 45m

Des Moines

Tue 12/30

6:50 pm-8:10 am

2 stops12h 20m

$393

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 10/10

5:15 pm-11:59 pm

1 stop7h 44m

Des Moines

Mon 10/13

6:07 am-12:22 pm

1 stop5h 15m

$417

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 3/3

2:33 pm-11:43 pm

2 stops10h 10m

Des Moines

Wed 3/4

8:00 am-6:53 pm

2 stops9h 53m

$417

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

6:41 am-2:31 pm

1 stop8h 50m

Des Moines

Mon 11/10

6:00 am-11:39 am

1 stop4h 39m

$417

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Wed 10/1

12:38 pm-6:30 pm

1 stop6h 52m

Des Moines

Sun 10/5

5:00 am-12:08 pm

1 stop6h 08m

$467

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 12/20

7:36 pm-10:26 pm

1 stop27h 50m

$210

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Mon 9/29

3:59 pm-9:40 pm

1 stop6h 41m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 15 results
1
2

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $336). Flying from Manchester, New Hampshire to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to DSM?

Find hourly flight availability from Manchester to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from Manchester, New Hampshire to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 14% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Des Moines?

    Southwest and American Airlines can get you from Manchester, New Hampshire to Des Moines in just under 7h 44m. Your travel time can differ by up to 4h 21m. Manchester, New Hampshire and Des Moines are separated by a distance of 1137 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Manchester, New Hampshire to Des Moines round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Des Moines round-trip from $316. American Airlines is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $336). Flying from Manchester, New Hampshire to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Manchester to Des Moines

Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$466FlexibilityNo cancel feeOn-time71%

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