$101+ Cheap flights from Houston to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — DSM
Apr 9 — Apr 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Houston to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Houston to Des Moines are usually found in May or July, booked 59 days in advance, depart on a Monday or Tuesday and return on a Wednesday
Cheap flight deals from Houston to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Houston to Des MoinesExplore the most affordable flight options available from Houston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Houston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:10 am
HOU
- DSM
Nonstop2h 12m
Allegiant Air
Mon 6/226:00 am
DSM
- HOU
Nonstop2h 20m
Allegiant Air
Deal found 3/5![Allegiant Air logo]()
$163
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/229:10 am
HOU
- DSM
Nonstop2h 12m
Allegiant Air
Fri 6/266:00 am
DSM
- HOU
Nonstop2h 20m
Allegiant Air
Deal found 3/6![Allegiant Air logo]()
$166
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
IAH
- DSM
1 stop5h 26m
American Airlines
Mon 4/135:01 pm
DSM
- IAH
1 stop6h 47m
American Airlines
Deal found 3/9![American Airlines logo]()
$169
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:45 am
IAH
- DSM
1 stop6h 44m
Frontier
Mon 5/112:20 pm
DSM
- IAH
1 stop10h 28m
Frontier
Deal found 3/6![Frontier logo]()
$181
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
IAH
- DSM
1 stop4h 34m
American Airlines
Wed 4/11:52 pm
DSM
- IAH
1 stop6h 50m
American Airlines
Deal found 3/8![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:05 pm
HOU
- DSM
1 stop5h 50m
Southwest
Mon 5/117:10 pm
DSM
- HOU
1 stop5h 15m
Southwest
Deal found 3/6![Southwest logo]()
$209
This Trip.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:56 pm
IAH
- DSM
1 stop20h 20m
Frontier
Sat 3/288:21 pm
DSM
- IAH
1 stop28h 18m
Frontier
Deal found 3/9![Frontier logo]()
$222
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
HOU
- DSM
1 stop4h 34m
American Airlines
Wed 4/17:27 pm
DSM
- HOU
1 stop4h 31m
American Airlines
Deal found 3/8![American Airlines logo]()
$224
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
IAH
- DSM
1 stop4h 34m
American Airlines
Sun 4/125:01 pm
DSM
- IAH
1 stop6h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:32 am
IAH
- DSM
1 stop10h 34m
Multiple Airlines
Mon 4/138:14 pm
DSM
- IAH
1 stop18h 53m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$227
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:17 pm
IAH
- DSM
Nonstop2h 27m
United Airlines
Sun 3/298:20 am
DSM
- IAH
Nonstop2h 35m
United Airlines
Deal found 3/5![United Airlines logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:15 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Sun 5/178:25 pm
DSM
- IAH
1 stop5h 34m
United Airlines
Deal found 3/6![United Airlines logo]()
$239
Best flights from Houston to Des MoinesDiscover carefully curated flight deals from Houston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Houston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:05 pm
HOU
- DSM
1 stop5h 50m
Southwest
Mon 5/117:10 pm
DSM
- HOU
1 stop5h 15m
Southwest
Deal found 3/6![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:01 am
HOU
- DSM
1 stop5h 25m
American Airlines
Sat 4/117:05 pm
DSM
- HOU
1 stop4h 42m
American Airlines
Deal found 3/9![American Airlines logo]()
$223
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:17 pm
IAH
- DSM
Nonstop2h 27m
United Airlines
Sun 3/298:20 am
DSM
- IAH
Nonstop2h 35m
United Airlines
Deal found 3/5![United Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:05 am
IAH
- DSM
1 stop5h 50m
Delta
Sat 4/2512:01 pm
DSM
- IAH
2 stops8h 17m
Delta
Deal found 3/6![Delta logo]()
$254
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:12 pm
IAH
- DSM
Nonstop2h 23m
United Airlines
Sun 6/76:20 am
DSM
- IAH
Nonstop2h 28m
United Airlines
Deal found 3/6![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:00 am
HOU
- DSM
1 stop4h 30m
Southwest
Tue 4/283:15 pm
DSM
- HOU
1 stop4h 40m
Southwest
Deal found 3/5![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:24 am
IAH
- DSM
1 stop5h 41m
Delta
Sat 5/94:15 pm
DSM
- IAH
2 stops7h 39m
Delta
Deal found 3/7![Delta logo]()
$254
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:04 am
IAH
- DSM
1 stop5h 23m
United Airlines
Sun 6/146:20 am
DSM
- IAH
Nonstop2h 28m
United Airlines
Deal found 3/6![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:40 am
HOU
- DSM
1 stop7h 25m
Southwest
Sun 5/178:40 pm
DSM
- HOU
1 stop8h 10m
Southwest
Deal found 3/9![Southwest logo]()
$249
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
HOU
- DSM
1 stop5h 05m
Delta
Sat 5/912:29 pm
DSM
- HOU
2 stops9h 57m
Delta
Deal found 3/7![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:00 am
HOU
- DSM
1 stop5h 40m
Southwest
Sun 4/56:45 am
DSM
- HOU
2 stops8h 40m
Southwest
Deal found 3/6![Southwest logo]()
$254
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:15 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Sun 5/178:25 pm
DSM
- IAH
1 stop5h 34m
United Airlines
Deal found 3/9![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:05 pm
HOU
- DSM
1 stop6h 30m
Southwest
Sat 4/256:40 am
DSM
- HOU
2 stops8h 30m
Southwest
Deal found 3/9![Southwest logo]()
$254
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 am
IAH
- DSM
1 stop5h 09m
United Airlines
Mon 4/138:20 am
DSM
- IAH
Nonstop2h 36m
United Airlines
Deal found 3/9![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
HOU
- DSM
2 stops7h 15m
Southwest
Wed 4/85:30 am
DSM
- HOU
2 stops10h 00m
Southwest
Deal found 3/5![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:23 am
IAH
- DSM
1 stop5h 00m
United Airlines
Sun 3/298:20 am
DSM
- IAH
Nonstop2h 35m
United Airlines
Deal found 3/6![United Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:23 am
IAH
- DSM
1 stop6h 01m
United Airlines
Sat 3/282:59 pm
DSM
- IAH
Nonstop2h 38m
United Airlines
Deal found 3/6![United Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Sun 4/128:20 am
DSM
- IAH
Nonstop2h 35m
United Airlines
Deal found 3/8![United Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:10 am
HOU
- DSM
1 stop7h 30m
Southwest
Sun 3/294:40 pm
DSM
- HOU
2 stops7h 55m
Southwest
Deal found 3/6![Southwest logo]()
$293
Last-minute flights from Houston to Des MoinesDiscover last-minute flight deals from Houston to Des Moines. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Des Moines. Data last updated March 10, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:56 pm
IAH
- DSM
1 stop20h 20m
Frontier
Sat 3/288:21 pm
DSM
- IAH
1 stop28h 18m
Frontier
Deal found 3/9![Frontier logo]()
$222
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
IAH
- DSM
1 stop4h 34m
American Airlines
Wed 4/11:52 pm
DSM
- IAH
1 stop6h 50m
American Airlines
Deal found 3/8![American Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
HOU
- DSM
1 stop4h 34m
American Airlines
Wed 4/17:27 pm
DSM
- HOU
1 stop4h 31m
American Airlines
Deal found 3/8![American Airlines logo]()
$224
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:17 pm
IAH
- DSM
Nonstop2h 27m
United Airlines
Sun 3/298:20 am
DSM
- IAH
Nonstop2h 35m
United Airlines
Deal found 3/6![United Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:17 pm
IAH
- DSM
Nonstop2h 27m
United Airlines
Sun 3/298:20 am
DSM
- IAH
Nonstop2h 35m
United Airlines
Deal found 3/5![United Airlines logo]()
$229
This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:45 am
IAH
- DSM
1 stop12h 31m
Frontier
Sat 3/288:21 pm
DSM
- IAH
1 stop12h 37m
Frontier
Deal found 3/7![Frontier logo]()
$240
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
HOU
- DSM
1 stop4h 34m
American Airlines
Wed 4/87:05 pm
DSM
- HOU
1 stop4h 42m
American Airlines
Deal found 3/5![American Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
IAH
- DSM
1 stop4h 34m
American Airlines
Sun 4/125:01 pm
DSM
- IAH
1 stop6h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$224
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
IAH
- DSM
1 stop5h 26m
American Airlines
Mon 4/135:01 pm
DSM
- IAH
1 stop6h 47m
American Airlines
Deal found 3/9![American Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:32 am
IAH
- DSM
1 stop10h 34m
Multiple Airlines
Mon 4/138:14 pm
DSM
- IAH
1 stop18h 53m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:25 pm
HOU
- DSM
1 stop7h 45m
Southwest
Tue 4/283:15 pm
DSM
- HOU
1 stop4h 40m
Southwest
Deal found 3/6![Southwest logo]()
$244
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:01 am
HOU
- DSM
1 stop5h 25m
American Airlines
Sat 4/257:05 pm
DSM
- HOU
1 stop4h 42m
American Airlines
Deal found 3/9![American Airlines logo]()
$243
One-way flights from Houston to Des MoinesSearch for one-way flight options from Houston to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Houston to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Priceline deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:45 am
IAH
- DSM
1 stop6h 44m
Frontier
Deal found 3/8![Frontier logo]()
$101
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:50 am
HOU
- DSM
1 stop9h 05m
Southwest
Deal found 3/5![Southwest logo]()
$105
This Super.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:56 pm
IAH
- DSM
1 stop20h 20m
Frontier
Deal found 3/7![Frontier logo]()
$113
This Expedia deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:45 am
IAH
- DSM
1 stop12h 31m
Frontier
Deal found 3/6![Frontier logo]()
$121
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:59 pm
IAH
- DSM
1 stop4h 00m
American Airlines
Deal found 3/8![American Airlines logo]()
$124
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:20 am
HOU
- DSM
1 stop9h 25m
Southwest
Deal found 3/6![Southwest logo]()
$125
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:05 am
HOU
- DSM
1 stop7h 35m
Southwest
Deal found 3/9![Southwest logo]()
$145
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:00 am
IAH
- DSM
1 stop5h 34m
American Airlines
Deal found 3/9![American Airlines logo]()
$164
This Expedia deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/148:24 am
IAH
- DSM
1 stop9h 37m
Frontier
Deal found 3/6![Frontier logo]()
$170
This Super.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:15 pm
IAH
- DSM
1 stop12h 15m
Frontier
Deal found 3/8![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:37 pm
IAH
- DSM
2 stops29h 24m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:15 pm
IAH
- DSM
2 stops44h 46m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$186
Find flight deals from Houston to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Round-trip from | $163 (Kiwi.com) |
|---|---|
One-way from | $101 (Priceline) |
Popular in | February |
Cheapest in | May |
Average price | $414 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Houston to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonDes Moines
HOU - DSM
HOUDSM
Houston Hobby
Fri 5/8
4:05 pm-9:55 pm
1 stop5h 50m
Des Moines
Mon 5/11
7:10 pm-12:25 am
1 stop5h 15m
$209
HoustonDes Moines
HOU - DSM
HOUDSM
Houston Hobby
Thu 4/9
6:01 am-11:26 am
1 stop5h 25m
Des Moines
Sat 4/11
7:05 pm-11:47 pm
1 stop4h 42m
$223
HoustonDes Moines
IAH - DSM
IAHDSM
Houston George Bush Intcntl
Fri 3/27
8:17 pm-10:44 pm
Nonstop2h 27m
Des Moines
Sun 3/29
8:20 am-10:55 am
Nonstop2h 35m
$229
Quickest round-trip
HoustonDes Moines
IAH - DSM
IAHDSM
Houston George Bush Intcntl
Fri 6/5
8:12 pm-10:35 pm
Nonstop2h 23m
Des Moines
Sun 6/7
6:20 am-8:48 am
Nonstop2h 28m
$229
HoustonDes Moines
IAH - DSM
IAHDSM
Houston George Bush Intcntl
Thu 6/11
5:04 am-10:27 am
1 stop5h 23m
Des Moines
Sun 6/14
6:20 am-8:48 am
Nonstop2h 28m
$239
HoustonDes Moines
HOU - DSM
HOUDSM
Houston Hobby
Sat 4/25
7:00 am-11:30 am
1 stop4h 30m
Des Moines
Tue 4/28
3:15 pm-7:55 pm
1 stop4h 40m
$244
HoustonDes Moines
HOU - DSM
HOUDSM
Houston Hobby
Wed 5/13
6:40 am-2:05 pm
1 stop7h 25m
Des Moines
Sun 5/17
8:40 pm-4:50 am
1 stop8h 10m
$249
HoustonDes Moines
IAH - DSM
IAHDSM
Houston George Bush Intcntl
Fri 4/17
8:05 am-1:55 pm
1 stop5h 50m
Des Moines
Sat 4/25
12:01 pm-8:18 pm
2 stops8h 17m
$254
HoustonDes Moines
IAH - DSM
IAHDSM
Houston George Bush Intcntl
Thu 4/30
5:24 am-11:05 am
1 stop5h 41m
Des Moines
Sat 5/9
4:15 pm-11:54 pm
2 stops7h 39m
$254
HoustonDes Moines
HOU - DSM
HOUDSM
Houston Hobby
Thu 4/2
8:00 am-1:40 pm
1 stop5h 40m
Des Moines
Sun 4/5
6:45 am-3:25 pm
2 stops8h 40m
$254
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Houston to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Houston with our price prediction graph.
HO1-DSM
HOU-DSM
IAH-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Des Moines
HO1-DSM
HOU-DSM
IAH-DSM
How far ahead should I book a flight from Houston to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from Houston to Des Moines. Price data was last updated on March 6, 2026.
Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from Houston to Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Houston to Des Moines?
Currently, May is the cheapest month in which you can book a flight from Houston to Des Moines (average of $45). Flying from Houston to Des Moines in January is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from HOU to DSM?
Find hourly flight availability from Houston to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 28% on flights from Houston to Des Moines by exploring options for tickets at noon.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 10, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAllegiant Air from Houston to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Houston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Popular flights
Alternative routes for Houston to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
Search flights from Houston to Des Moines by cabin class
Find flights from Houston to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Des Moines flights
Browse other Houston and Des Moines flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Houston to Des Moines
Discover the top 4 airlines that operate flights from Houston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$44 | Average$83 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$203 | Average$331 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$214 | Average$387 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$216 | Average$317 | FlexibilityNo cancel fee | On-time71% |