$891+ Cheap flights from the Czech Republic to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — DSM
Jan 22 — Jan 291
1 adult, Economy
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Best flights from Czech Republic to Des MoinesDiscover carefully curated flight deals from Czech Republic to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.
Discover carefully curated flight deals from Czech Republic to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:10 amPRG - DSM
2 stops22h 30mAmerican Airlines
Mon 4/206:19 pmDSM - PRG
2 stops15h 41mAmerican Airlines
Deal found 12/20![American Airlines logo]()
$891
Find flight deals from Czech Republic to Des Moines
Keep the following information in mind while searching for Czech Republic to Des Moines flight deals. Data was last updated December 23, 2025.
Most accurate provider | Expedia 2 stars |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $891 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Czech Republic to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from the Czech Republic to Des Moines that are best for you.
Fly from
Czech Republic
Fly to
Des Moines
Route
Depart
Return
Price
PragueDes Moines
PRG - DSM
PRGDSM
Václav Havel Prague
Thu 4/16
7:10 am-10:40 pm
2 stops22h 30m
Des Moines
Mon 4/20
6:19 pm-5:00 pm
2 stops15h 41m
$891
Best time to book a flight from Czech Republic to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Czech Republic with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the Czech Republic to Des Moines
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