$280+ Cheap flights from La Crosse to Denver (LSE - DEN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — DEN
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Find cheap flights from La Crosse to Denver with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to Denver
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Best
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One-way
Cheapest flights from La Crosse to DenverExplore the most affordable flight options available from La Crosse to Denver. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from La Crosse to Denver. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:22 pm -
1 stop7h 55m
Sat 9/126:01 pm -
1 stop5h 19m
Deal found 9/2![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:26 pm -
2 stops11h 08m
Tue 10/61:07 pm -
2 stops9h 52m
Deal found 8/31![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:53 am -
1 stop5h 09m
Sat 9/268:18 am -
1 stop7h 34m
Deal found 9/2![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:22 pm -
1 stop7h 55m
Tue 10/66:09 pm -
1 stop4h 50m
Deal found 9/2![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:24 pm -
2 stops10h 51m
Tue 9/153:13 pm -
2 stops8h 07m
Deal found 8/31![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:55 pm -
1 stop6h 41m
Wed 10/2111:59 pm -
2 stops10h 54m
Deal found 9/4![American Airlines logo]()
$364
Best flights from La Crosse to DenverDiscover carefully curated flight deals from La Crosse to Denver that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from La Crosse to Denver that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:26 pm -
2 stops11h 08m
Tue 10/61:07 pm -
2 stops9h 52m
Deal found 8/31![American Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:08 pm -
1 stop14h 02m
Thu 10/1510:44 pm -
1 stop19h 32m
Deal found 8/31![Multiple Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:22 pm -
1 stop7h 55m
Wed 9/306:01 pm -
1 stop5h 19m
Deal found 9/3![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:22 pm -
1 stop7h 55m
Tue 9/226:01 pm -
1 stop5h 19m
Deal found 8/31![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:53 am -
1 stop5h 09m
Sat 9/268:18 am -
1 stop7h 34m
Deal found 9/2![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:55 pm -
1 stop6h 41m
Wed 10/216:09 pm -
1 stop4h 50m
Deal found 9/4![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:22 pm -
1 stop7h 55m
Tue 10/61:07 pm -
2 stops9h 52m
Deal found 8/31![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:17 pm -
1 stop6h 05m
Tue 1/125:30 am -
2 stops13h 06m
Deal found 9/1![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:55 pm -
1 stop5h 03m
Mon 10/196:09 pm -
1 stop4h 50m
Deal found 9/4![American Airlines logo]()
$430
Last-minute flights from La Crosse to DenverDiscover last-minute flight deals from La Crosse to Denver. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to Denver. Data last updated September 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:24 pm -
2 stops10h 51m
Tue 9/153:13 pm -
2 stops8h 07m
Deal found 8/31![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:22 pm -
1 stop7h 55m
Sat 9/126:01 pm -
1 stop5h 19m
Deal found 9/2![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:53 am -
1 stop5h 09m
Sat 9/268:18 am -
1 stop7h 34m
Deal found 9/2![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:22 pm -
1 stop7h 55m
Tue 10/66:09 pm -
1 stop4h 50m
Deal found 9/2![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:26 pm -
2 stops11h 08m
Tue 10/61:07 pm -
2 stops9h 52m
Deal found 8/31![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:55 pm -
1 stop6h 41m
Wed 10/2111:59 pm -
2 stops10h 54m
Deal found 9/4![American Airlines logo]()
$364
One-way flights from La Crosse to DenverSearch for one-way flight options from La Crosse to Denver. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
Search for one-way flight options from La Crosse to Denver. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:53 am -
1 stop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![American Airlines logo]()
$494
Find flight deals from La Crosse to Denver
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Denver (DEN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $280 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Denver that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from La Crosse to Denver that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Sat 10/3
12:26 pm-10:34 pm
2 stops11h 08m
Denver Intl
Tue 10/6
1:07 pm-11:59 pm
2 stops9h 52m
$291
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Tue 9/22
5:22 pm-12:17 am
1 stop7h 55m
Denver Intl
Wed 9/30
6:01 pm-12:20 am
1 stop5h 19m
$352
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Sat 9/19
5:22 pm-12:17 am
1 stop7h 55m
Denver Intl
Tue 9/22
6:01 pm-12:20 am
1 stop5h 19m
$352
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Tue 9/22
5:53 am-10:02 am
1 stop5h 09m
Denver Intl
Sat 9/26
8:18 am-4:52 pm
1 stop7h 34m
$352
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Thu 10/15
6:55 pm-12:36 am
1 stop6h 41m
Denver Intl
Wed 10/21
6:09 pm-11:59 pm
1 stop4h 50m
$355
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Fri 10/2
5:22 pm-12:17 am
1 stop7h 55m
Denver Intl
Tue 10/6
1:07 pm-11:59 pm
2 stops9h 52m
$361
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Fri 1/8
12:17 pm-5:22 pm
1 stop6h 05m
Denver Intl
Tue 1/12
5:30 am-7:36 pm
2 stops13h 06m
$361
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Mon 10/12
8:08 pm-9:10 am
1 stop14h 02m
Denver Intl
Thu 10/15
10:44 pm-7:16 pm
1 stop19h 32m
$397
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Thu 10/15
6:55 pm-10:58 pm
1 stop5h 03m
Denver Intl
Mon 10/19
6:09 pm-11:59 pm
1 stop4h 50m
$430
Quickest round-trip
La CrosseDenver
LSE La Crosse - DEN Denver Intl
LSEDEN
La Crosse
Sat 9/12
5:53 am-11:35 am
1 stop6h 42m
Denver Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$494
Sorted by cheapest first
Compare providers for flights from La Crosse to Denver
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to Denver in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on La Crosse-Denver flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Denver flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Denver flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-Denver flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Denver flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to Denver
Have a flexible travel schedule? Discover the best time to fly to Denver from La Crosse with our price prediction graph.
LSE-DEN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Denver
Get insights into the airlines that provide service to Denver. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Denver. Reviews last updated September 5, 2026.
Get a feel of what it's like to fly with American Airlines from La Crosse to Denver by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Crew
7.9
Food
6.4
Comfort
7.2
Boarding
7.5
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Crew
7.9
Food
6.4
Comfort
7.2
Boarding
7.5
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Denver. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Denver?
Book flights to Denver if you plan to visit one of these locationsThornton
Westminster
Lakewood
Black Hawk
Centennial
Broomfield
Golden
Wheat Ridge
Silverthorne
Central City
Fort Morgan
Greeley
Cripple Creek
Winter Park
Limon
Manitou Springs
Frisco
Englewood
Glendale
Evergreen
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Denver
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La Crosse and Denver flights
Browse other La Crosse and Denver flight options. Last updated on September 5, 2026.
Other flights from La Crosse
Browse through other flights departing from La Crosse. Flights are based on user searches made on Cheapflights and were last updated on September 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from La Crosse to Denver
Discover the top airline that operate flights from La Crosse to Denver. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$316 | Average$508 | FlexibilityNo cancel fee | On-time71% |