How long is the flight from Missouri to Cusco?

For as low as $953, American Airlines can have you in Cusco from Missouri in 18h 45m. The distance between Missouri and Cusco is about 3801 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Cusco ranges from 0.0 - 5.5 inches per month. January is typically the wettest month, when rainfall can reach 5.5 in. May is typically the driest time to visit Cusco when rainfall is around 0.0 in.

If weather is an important factor for your trip to Cusco, use this chart to help with planning. For those seeking warmer temperatures, October is the ideal time of year to visit, when temperatures reach an average of 55.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

What is the cheapest time of day to fly from MO to CUZ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cusco as you normally would.

What airport do you fly into for flights to Cusco from Missouri?

If you book a flight to Cusco from Missouri, you will be flying to Velazco Astete, which is the city’s only airport. Cusco Velazco Astete (CUZ) is located 1.7 mi from the center of Cusco.

Can I find deals for flights from Missouri to Cuzco that include hotel bookings?

Yes. In addition to deals on Missouri to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Cuzco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cuzco.

Can I find deals for business class flights from Missouri to Cuzco?

Yes. Cheapflights offers flight deals from Missouri to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$324+ Flights from Missouri to Cusco

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Cheap flight deals from Missouri to Cuzco

Cheapest flights from Missouri to Cuzco
Explore the most affordable flight options available from Missouri to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Fri 12/198:09 amMCI - CUZ

2 stops21h 21mMultiple Airlines

Sun 1/47:05 amCUZ - MCI

3 stops27h 13mMultiple Airlines

Deal found 12/13

$3,826

Fri 12/1910:24 amMCI - CUZ

2 stops13h 16mLATAM Airlines

Sun 1/411:15 pmCUZ - MCI

2 stops24h 36mLATAM Airlines

Deal found 12/13

$3,902

Best flights from Missouri to Cuzco
Discover carefully curated flight deals from Missouri to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 15, 2025.

Mon 1/1911:26 amMCI - CUZ

2 stops17h 59mMultiple Airlines

Wed 2/46:35 pmCUZ - MCI

2 stops16h 56mMultiple Airlines

Deal found 12/13

$448

Mon 4/135:14 amMCI - CUZ

2 stops25h 10mAmerican Airlines

Mon 4/2010:22 pmCUZ - MCI

2 stops25h 01mAmerican Airlines

Deal found 12/13

$935

Tue 3/246:00 amSTL - CUZ

2 stops18h 45mLATAM Airlines

Fri 4/36:50 amCUZ - STL

2 stops16h 52mLATAM Airlines

Deal found 12/13

$953

Mon 1/197:00 amMCI - CUZ

3 stops23h 26mBritish Airways

Wed 2/48:57 pmCUZ - MCI

3 stops20h 17mBritish Airways

Deal found 12/13

$1,176

Tue 3/2411:22 amSTL - CUZ

2 stops19h 04mAmerican Airlines

Fri 4/38:57 pmCUZ - STL

2 stops20h 43mAmerican Airlines

Deal found 12/15

$961

Wed 5/2710:35 amMCI - CUZ

2 stops22h 20mLATAM Airlines

Thu 6/48:25 amCUZ - MCI

2 stops15h 30mLATAM Airlines

Deal found 12/12

$986

Sat 3/287:10 amSTL - CUZ

2 stops24h 10mLATAM Airlines

Wed 4/89:20 pmCUZ - STL

2 stops26h 22mLATAM Airlines

Deal found 12/13

$1,014

Sun 5/3111:12 amMCI - CUZ

2 stops20h 12mAmerican Airlines

Sun 6/710:22 pmCUZ - MCI

2 stops24h 55mAmerican Airlines

Deal found 12/14

$1,061

Sun 2/155:00 pmSTL - CUZ

2 stops16h 45mLATAM Airlines

Wed 2/187:00 pmCUZ - STL

2 stops17h 02mLATAM Airlines

Deal found 12/14

$1,102

Sat 3/74:05 pmSTL - CUZ

2 stops18h 15mMultiple Airlines

Fri 3/137:02 amCUZ - STL

3 stops32h 27mMultiple Airlines

Deal found 12/13

$1,494

Sat 3/75:00 pmSTL - CUZ

2 stops30h 45mLATAM Airlines

Fri 3/1311:20 pmCUZ - STL

2 stops24h 22mLATAM Airlines

Deal found 12/13

$1,289

Fri 3/136:20 pmSTL - CUZ

2 stops13h 06mAmerican Airlines

Fri 3/204:57 pmCUZ - STL

2 stops17h 39mAmerican Airlines

Deal found 12/13

$1,432

Fri 3/134:05 pmSTL - CUZ

2 stops25h 10mMultiple Airlines

Fri 3/206:50 amCUZ - STL

3 stops32h 39mMultiple Airlines

Deal found 12/13

$2,068

Wed 5/272:31 pmMCI - CUZ

3 stops16h 53mAmerican Airlines

Thu 6/411:47 amCUZ - MCI

2 stops23h 07mAmerican Airlines

Deal found 12/12

$2,033

Last-minute flights from Missouri to Cuzco
Discover last-minute flight deals from Missouri to Cuzco. Data last updated December 15, 2025 and is based on user searches.

Fri 12/198:09 amMCI - CUZ

2 stops21h 21mMultiple Airlines

Sun 1/47:05 amCUZ - MCI

3 stops27h 13mMultiple Airlines

Deal found 12/13

$3,826

Fri 12/1910:24 amMCI - CUZ

2 stops13h 16mLATAM Airlines

Sun 1/411:15 pmCUZ - MCI

2 stops24h 36mLATAM Airlines

Deal found 12/13

$3,902

Mon 1/1911:26 amMCI - CUZ

2 stops17h 59mMultiple Airlines

Wed 2/46:35 pmCUZ - MCI

2 stops16h 56mMultiple Airlines

Deal found 12/13

$448

Mon 1/197:00 amMCI - CUZ

3 stops23h 26mBritish Airways

Wed 2/48:57 pmCUZ - MCI

3 stops20h 17mBritish Airways

Deal found 12/13

$1,176

Wed 1/281:22 pmMCI - CUZ

2 stops20h 53mLATAM Airlines

Wed 2/47:00 pmCUZ - MCI

2 stops15h 39mLATAM Airlines

Deal found 12/14

$1,167

Thu 1/299:59 amSTL - CUZ

2 stops13h 46mLATAM Airlines

Thu 2/57:35 amCUZ - STL

2 stops17h 02mLATAM Airlines

Deal found 12/15

$972

Thu 1/294:05 pmSTL - CUZ

2 stops18h 15mMultiple Airlines

Thu 2/55:00 amCUZ - STL

3 stops35h 29mMultiple Airlines

Deal found 12/15

$1,477

One-way flights from Missouri to Cuzco
Search for one-way flight options from Missouri to Cuzco. Find affordable one-way fares based on user searches. Data last updated December 15, 2025.

Mon 1/198:39 amSTL - CUZ

3 stops37h 51mMultiple Airlines

Deal found 12/15

$324

Tue 3/3111:21 amSTL - CUZ

3 stops59h 04mMultiple Airlines

Deal found 12/15

$394

Mon 1/196:02 pmSTL - CUZ

2 stops26h 24mAmerican Airlines

Deal found 12/15

$599

Thu 1/155:50 amMCI - CUZ

2 stops28h 50mLATAM Airlines

Deal found 12/13

$774

Find flight deals from Missouri to Cuzco

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$448 (flugladen.de)
One-way from	$324 (Kiwi.com)
Popular in	November
Cheapest in	December
Average price	$885

Provider with most accurate pricing for Lambert-St Louis-Cusco Velazco Astete flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Cusco Velazco Astete flights.

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From Missouri to Cusco Velazco Astete

Search Deals

One-way flight from Missouri to Cusco Velazco Astete

Search Deals

Highest demand for flights based on searches. 1% potential increase in price ($18 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($28 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Mon 1/19

11:26 am-6:25 am

2 stops17h 59m

Cusco Velazco Astete

Wed 2/4

6:35 pm-10:31 am

2 stops16h 56m

$448

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Mon 4/13

5:14 am-6:24 am

2 stops25h 10m

Cusco Velazco Astete

Mon 4/20

10:22 pm-11:23 pm

2 stops25h 01m

$935

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 3/24

6:00 am-12:45 am

2 stops18h 45m

Cusco Velazco Astete

Fri 4/3

6:50 am-11:42 pm

2 stops16h 52m

$953

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 3/24

11:22 am-6:26 am

2 stops19h 04m

Cusco Velazco Astete

Fri 4/3

8:57 pm-5:40 pm

2 stops20h 43m

$961

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Wed 5/27

10:35 am-8:55 am

2 stops22h 20m

Cusco Velazco Astete

Thu 6/4

8:25 am-11:55 pm

2 stops15h 30m

$986

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 3/28

7:10 am-7:20 am

2 stops24h 10m

Cusco Velazco Astete

Wed 4/8

9:20 pm-11:42 pm

2 stops26h 22m

$1,014

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Sun 5/31

11:12 am-7:24 am

2 stops20h 12m

Cusco Velazco Astete

Sun 6/7

10:22 pm-11:17 pm

2 stops24h 55m

$1,061

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 2/15

5:00 pm-10:45 am

2 stops16h 45m

Cusco Velazco Astete

Wed 2/18

7:00 pm-11:02 am

2 stops17h 02m

$1,102

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Mon 1/19

7:00 am-7:26 am

3 stops23h 26m

Cusco Velazco Astete

Wed 2/4

8:57 pm-4:14 pm

3 stops20h 17m

$1,176

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 3/7

5:00 pm-12:45 am

2 stops30h 45m

Cusco Velazco Astete

Fri 3/13

11:20 pm-11:42 pm

2 stops24h 22m

$1,289

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 18 results

Best time to book a flight from Missouri to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Cusco

What is the cheapest month to book a flight from Missouri to Cusco?

Currently, December is the cheapest month in which you can book a flight from Missouri to Cusco (average of $748). Flying from Missouri to Cusco in August is currently the most expensive (average of $1,351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

What airport do you fly into for flights to Cusco from Missouri?
If you book a flight to Cusco from Missouri, you will be flying to Velazco Astete, which is the city’s only airport. Cusco Velazco Astete (CUZ) is located 1.7 mi from the center of Cusco.
How long is the flight from Missouri to Cusco?
For as low as $953, American Airlines can have you in Cusco from Missouri in 18h 45m. The distance between Missouri and Cusco is about 3801 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Missouri to Cuzco that include hotel bookings?
Yes. In addition to deals on Missouri to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Cuzco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cuzco.
Can I find deals for business class flights from Missouri to Cuzco?
Yes. Cheapflights offers flight deals from Missouri to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Cusco?
Currently, December is the cheapest month in which you can book a flight from Missouri to Cusco (average of $748). Flying from Missouri to Cusco in August is currently the most expensive (average of $1,351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Missouri to Cuzco

Airline	Cheapest	Average	Flexibility	On-time
LATAM Airlines	Cheapest$798	Average$1,187	FlexibilityNo cancel fee	On-time81%

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$324+ Cheap flights from Missouri to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Cuzco with Cheapflights

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Cheap flight deals from Missouri to Cuzco

Cheapest flights from Missouri to CuzcoExplore the most affordable flight options available from Missouri to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Explore the most affordable flight options available from Missouri to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Find flight deals from Missouri to Cuzco

Keep the following information in mind while searching for Missouri to Cuzco flight deals. Data was last updated December 15, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Cusco that are best for you.

Best time to book a flight from Missouri to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Cusco

What is the cheapest month to book a flight from Missouri to Cusco?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Cusco from Missouri?

How long is the flight from Missouri to Cusco?

Can I find deals for flights from Missouri to Cuzco that include hotel bookings?

How can I find direct flights from Missouri to Cuzco?

Can I find deals for business class flights from Missouri to Cuzco?

What is the cheapest month to book a flight from Missouri to Cusco?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Cuzco

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Top airline flying from Missouri to Cuzco

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Cheapest flights from Missouri to Cuzco
Explore the most affordable flight options available from Missouri to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.