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Cuzco

$635+ Cheap flights from Missouri to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Aug 7 — Aug 141
Thu 8/7
Thu 8/14
1 adult, Economy
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Cheap flight deals from Missouri to Cuzco

Keep the following information in mind while searching for Missouri to Cuzco flight deals. Data was last updated August 2, 2025.

Round-trip from

$635
(Mytrip)

Popular in

October

Cheapest in

February

Average price

$1,586
From Missouri to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($100 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($52 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
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Find flight deals from Missouri to Cuzco

Cheapest flights from Missouri to Cuzco
Explore the most affordable flight options available from Missouri to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2810:37 amSTL - CUZ
3 stops34h 27mMultiple Airlines
Wed 9/108:02 amCUZ - STL
3 stops25h 38mMultiple Airlines
Deal found 7/30$635
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2511:44 amMCI - CUZ
3 stops19h 40mMultiple Airlines
Tue 9/99:47 pmCUZ - MCI
3 stops25h 20mMultiple Airlines
Deal found 7/30$680
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/281:30 pmSTL - CUZ
2 stops21h 10mDelta
Wed 9/107:00 pmCUZ - STL
2 stops19h 35mDelta
Deal found 7/30$718
This LATAM Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:00 amSTL - CUZ
2 stops23h 15mLATAM Airlines
Thu 11/136:20 pmCUZ - STL
2 stops24h 42mLATAM Airlines
Deal found 7/31$777
This Flysmarter deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/253:00 pmMCI - CUZ
3 stops16h 24mBritish Airways
Tue 9/98:57 pmCUZ - MCI
2 stops27h 02mBritish Airways
Deal found 7/30$1,077
This LATAM Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/84:15 pmMCI - CUZ
2 stops25h 10mLATAM Airlines
Wed 12/102:40 pmCUZ - MCI
2 stops19h 53mLATAM Airlines
Deal found 7/30$1,168
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:00 amMCI - CUZ
2 stops25h 26mAmerican Airlines
Wed 12/1011:02 amCUZ - MCI
2 stops37h 31mAmerican Airlines
Deal found 7/31$1,175
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/164:25 pmSTL - CUZ
3 stops14h 54mAmerican Airlines
Tue 10/2810:02 pmCUZ - STL
2 stops25h 54mAmerican Airlines
Deal found 7/30$2,029

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Missouri to Cusco that are best for you.

Fly from

Missouri

Fly to

Cuzco

Route

Depart

Return

Price

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Thu 8/28

10:37 am-9:04 pm

3 stops34h 27m

Cusco Velazco Astete

Wed 9/10

8:02 am-9:40 am

3 stops25h 38m

$635

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Mon 8/25

11:44 am-7:24 am

3 stops19h 40m

Cusco Velazco Astete

Tue 9/9

9:47 pm-11:07 pm

3 stops25h 20m

$680

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Thu 8/28

1:30 pm-10:40 am

2 stops21h 10m

Cusco Velazco Astete

Wed 9/10

7:00 pm-2:35 pm

2 stops19h 35m

$718

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 11/9

6:00 am-6:15 am

2 stops23h 15m

Cusco Velazco Astete

Thu 11/13

6:20 pm-6:02 pm

2 stops24h 42m

$777

Kansas CityCusco

MCI - CUZ

MCICUZ

Kansas City

Mon 8/25

3:00 pm-7:24 am

3 stops16h 24m

Cusco Velazco Astete

Tue 9/9

8:57 pm-11:59 pm

2 stops27h 02m

$1,077

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Thu 10/16

6:08 pm-7:19 am

2 stops13h 11m

Cusco Velazco Astete

Tue 10/28

4:37 pm-12:06 pm

3 stops19h 29m

$2,029

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Missouri to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Cusco

What is the cheapest month to book a flight from Missouri to Cusco?

Currently, February is the cheapest month in which you can book a flight from Missouri to Cusco (average of $789). Flying from Missouri to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CUZ?

Find hourly flight availability from Missouri to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cusco as you normally would.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated August 2, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Missouri to Cusco have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,823 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
British Airways
6.6
Okay
7,224 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cusco from Missouri?

    If you book a flight to Cusco from Missouri, you will be flying to Velazco Astete, which is the city’s only airport. Cusco Velazco Astete (CUZ) is located 1.7 mi from the center of Cusco.

  • Can I find deals for flights from Missouri to Cuzco that include hotel bookings?

    Yes. In addition to deals on Missouri to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cuzco.

  • Can I find deals for business class flights from Missouri to Cuzco?

    Yes. Cheapflights offers flight deals from Missouri to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Cusco?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Cusco (average of $789). Flying from Missouri to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Cuzco

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Top airline flying from Missouri to Cuzco

Discover the top airline that operate flights from Missouri to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$776Average$985FlexibilityNo cancel feeOn-time81%

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