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$138+ Cheap flights from Cusco (CUZ) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
CUZ — SCL
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheapflights Tip: The best prices from Cusco Velazco Astete to Santiago Arturo Merino Benitez are usually found in October or December, booked 16 days in advance, depart on a Monday or Friday and return on a Saturday

Cheap flight deals from Cuzco to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cuzco (CUZ) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 1, 2025.

Round-trip from

$301
(Sky Airline)

One-way from

$138
(FlightHub)

Popular in

June

Cheapest in

October

Average price

$333

Good one-way deal

$148 or less
From Cusco Velazco Astete to Santiago Arturo Merino Benitez
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One-way flight from Cusco Velazco Astete to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 13% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a one-way flight from Cusco Velazco Astete to Santiago Arturo Merino Benitez.
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Find flight deals from Cuzco to Santiago

Cheapest flights from Cuzco to Santiago
Explore the most affordable flight options available from Cuzco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Sky Airline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/137:25 amCUZ - SCL
1 stop12h 50mSky Airline
Sat 10/2511:05 pmSCL - CUZ
2 stops12h 10mSky Airline
Deal found 6/30$301
This LATAM Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:40 pmCUZ - SCL
2 stops13h 31mLATAM Airlines
Tue 8/52:40 pmSCL - CUZ
Nonstop3h 35mLATAM Airlines
Deal found 6/30$338
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2910:10 amCUZ - SCL
1 stop9h 47mMultiple Airlines
Mon 8/412:45 amSCL - CUZ
2 stops17h 20mMultiple Airlines
Deal found 7/1$352
This Booking.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:40 pmCUZ - SCL
2 stops12h 25mAerolineas Argentinas
Fri 8/88:55 amSCL - CUZ
2 stops15h 25mAerolineas Argentinas
Deal found 6/30$1,217
This Avianca deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/112:15 pmCUZ - SCL
1 stop15h 00mAvianca
Thu 8/711:55 pmSCL - CUZ
1 stop12h 05mAvianca
Deal found 6/30$1,473

Cheapflights Fare Finder

Customize your flight search to find flights from Cuzco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Cuzco

Fly to

Santiago

Route

Depart

Return

Price

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sat 9/13

7:25 am-10:15 pm

1 stop12h 50m

Santiago Arturo Merino Benitez

Sat 10/25

11:05 pm-9:15 am

2 stops12h 10m

$301

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 8/4

6:40 pm-9:11 am

2 stops13h 31m

Santiago Arturo Merino Benitez

Tue 8/5

2:40 pm-5:15 pm

Nonstop3h 35m

$338

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Tue 7/29

10:10 am-8:57 pm

1 stop9h 47m

Santiago Arturo Merino Benitez

Mon 8/4

12:45 am-5:05 pm

2 stops17h 20m

$352

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 7/25

6:40 pm-8:05 am

2 stops12h 25m

Santiago Arturo Merino Benitez

Fri 8/8

8:55 am-11:20 pm

2 stops15h 25m

$1,217

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 8/1

12:15 pm-4:15 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Thu 8/7

11:55 pm-11:00 am

1 stop12h 05m

$1,473

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Wed 9/24

7:25 am-12:00 pm

2 stops26h 35m

$138

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sat 10/18

6:50 am-9:55 pm

1 stop13h 05m

$150

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 9/26

8:57 pm-5:01 am

1 stop6h 04m

$164

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 9/25

9:57 pm-12:00 pm

2 stops12h 03m

$178

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Cuzco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cuzco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cusco to Santiago

How far ahead should I book a flight from Cusco to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cuzco to Santiago. Price data was last updated on June 27, 2025.

To ensure you get the cheapest price possible for a flight from Cusco to Santiago, you should look to book at least 16 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cusco to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cusco to Santiago (average of $752). Flying from Cusco to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUZ to SCL?

Find hourly flight availability from Cuzco to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

When flying from Cusco to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 12% versus a flight at noon.

Weekly flight availability from Cusco to Santiago

Explore weekly flight availability from Cuzco to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 1, 2025.

The most flights from CUZ to SCL are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Cusco to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 1, 2025.
Read through reviews of airlines operating flights from Cusco to Santiago, such as Aerolineas Argentinas, LATAM Airlines, and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.1
Very good
889 reviews

Boarding

8.0

Entertainment

5.7

Comfort

7.5

Food

6.4

Crew

8.3

Overall

8.1

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Aerolineas Argentinas
8.1
Very good
889 reviews
Aerolineas Argentinas
8.1
Very good
889 reviews

Boarding

8.0

Entertainment

5.7

Comfort

7.5

Food

6.4

Crew

8.3

Overall

8.1

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
LATAM Airlines
7.5
Good
1,801 reviews
Aerolineas Argentinas
8.1
Very good
889 reviews

Boarding

8.0

Entertainment

5.7

Comfort

7.5

Food

6.4

Crew

8.3

Overall

8.1

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Avianca
6.7
Okay
2,362 reviews
Aerolineas Argentinas
8.1
Very good
889 reviews

Boarding

8.0

Entertainment

5.7

Comfort

7.5

Food

6.4

Crew

8.3

Overall

8.1

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
JetSMART
6.6
Okay
201 reviews
Aerolineas Argentinas
8.1
Very good
889 reviews

Boarding

8.0

Entertainment

5.7

Comfort

7.5

Food

6.4

Crew

8.3

Overall

8.1

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.

Related info for your journey

Find useful and relevant information for your journey from Cuzco to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Cusco to Santiago?

    Booking a flight from Cusco Velazco Astete (CUZ) to Santiago Arturo Merino Benitez (SCL) is your only option if you wish to fly from Cusco to Santiago. On a typical day, there is 1 flight from Velazco Astete to Arturo Merino Benitez, all of which are around 3h 20m for a nonstop flight. You can also purchase a plane ticket from 1 airline when you book a flight from Velazco Astete to Santiago.

  • What are the cheapest airlines flying from Cusco to Santiago round-trip?

    Flying on Sky Airline is currently your cheapest option to Santiago, with prices starting at $301. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and Aerolineas Argentinas, with the lowest prices starting at $338 and $1,217, respectively. Users have found that Sky Airline is 4% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Cusco to Santiago one-way?

    To fly one-way, consider booking your trip with Sky Airline, which is currently one of the cheapest options available, starting at $138. LATAM Airlines flights start at $150 while deals on JetSMART start at $154 one-way.

  • What are the cheapest flights from Cusco to Santiago?

    While on average a flight from Cusco to Santiago is generally $257, our data shows the cheapest flight currently is $146. When looking at the most popular route, (Cusco Velazco Astete - Santiago Arturo Merino Benitez), you can expect to pay $349 for that flight.

  • Can I find deals for flights from Cuzco to Santiago that include hotel bookings?

    Yes. In addition to deals on Cuzco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cuzco to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to Santiago.

  • Can I find deals for business class flights from Cuzco to Santiago?

    Yes. Cheapflights offers flight deals from Cuzco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cusco to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cusco to Santiago (average of $752). Flying from Cusco to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Cuzco to Santiago

Discover the top airline that operate flights from Cuzco to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$275Average$414FlexibilityNo cancel feeOn-time81%

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